Valor pronóstico de la citología positiva hallada en el lavado pleural de pacientes con cáncer de pulmón. Estudio prospectivo

Arnau Obrer, A.; Cantó Armengod, A.; Martín Díaz, E.

doi:10.1016/S0300-2896(15)30736-5

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"apellidos" => "Ramón Capilla" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "*" "identificador" => "aff0010" ] ] ] 2 => array:3 [ "nombre" => "R." "apellidos" => "García Aguado" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "**" "identificador" => "aff0015" ] ] ] 3 => array:3 [ "nombre" => "M." "apellidos" => "Martorell Cebollada" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "***" "identificador" => "aff0020" ] ] ] ] "afiliaciones" => array:3 [ 0 => array:3 [ "entidad" => "Servicios de Neumología, Hospital General Universitario de Valencia" "etiqueta" => "*" "identificador" => "aff0010" ] 1 => array:3 [ "entidad" => "Servicios de Ancstesia y Reanimación, Hospital General Universitario de Valencia" "etiqueta" => "**" "identificador" => "aff0015" ] 2 => array:3 [ "entidad" => "Servicios de Anatomía Patológica. Hospital General Universitario de Valencia" "etiqueta" => "***" "identificador" => "aff0020" ] ] ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Prognostic value of positive findings of pleural lavage cytology in lung cancer patients. A prospective study" ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "1995-06-15" "fechaAceptado" => "1996-01-30" "PalabrasClave" => array:2 [ "es" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palabras clave" "identificador" => "xpalclavsec546160" "palabras" => array:3 [ 0 => "Cáncer de pulmón" 1 => "Lavados pleurales" 2 => "Citología pleural" ] ] ] "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Key words" "identificador" => "xpalclavsec546161" "palabras" => array:3 [ 0 => "Lung cancer" 1 => "Pleural lavage" 2 => "Pleural cytology" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "es" => array:1 [ "resumen" => "Existe la posibilidad de que las neoplasias pulmonares puedan emitir células malignas a la cavidad pleural por distintos mecanismos. Esta posibilidad depende no sólo del tipo histológico, sino también del estadio clínico.Se analiza si la citología maligna hallada en el lavado pleural influye en la supervivencia y aparición de metástasis pleurales en su evolución postoperatoria.Presentamos una serie de 200 pacientes intervenidos quirúrgicamente en el Hospital General Universitario de Valencia desde el 1 de febrero de 1990 al 30 de marzo de 1993.Consta de dos grupos: el grupo primero está formado por 150 pacientes diagnosticados de cáncer de pulmón (CP), ninguno de los cuales tuvo derrame pleural previo ni sufrió punción transtorácica durante su estudio preoperatorio. Se excluyen de este grupo los pacientes tratados con quimioterapia (QT) o radioterapia (RT) neoadyuvantes, con el fin de evitar falsos positivos, y el grupo segundo o grupo testigo estaba formado por 50 pacientes sin patología tumoral a los que se realizó toracotomía por otras circunstancias.A todos ellos se les practicó lavados pleurales con suero fisiológico antes y después de las maniobras destinadas a la exéresis pulmonar.Encontramos un 26,6% (40/150) de citologías positivas en la totalidad de lavados pre y posquirúrgicos del grupo primero. No encontramos citologías positivas en el grupo testigo." ] "en" => array:1 [ "resumen" => "Pulmonary neoplasms can deposit malignant cells in the pleural cavity by a variety of mechanisms, depending not only on histological type but also on clinical stage.We investigated the effect on survival rate of a finding of malignant cells in pleural lavage. We also investigated the effect of the presence of pleural metastasis on postoperative course of disease.Two hundred surgical patients at Hospital General Universitario in Valencia between 1 February 1990 and 30 March 1993 were studied.Two groups were formed. Group one: 150 patients with lung cancer, none of whom had had pleural effusion prior to suffering transthoracic puncture during the preoperative study. Patients treated with parallel chemotherapy or radiotherapy were excluded in order to circumvent false positives. Group two: 50 patients with no tumors who underwent thoracotomy for reasons other than lung cancer.All patients underwent pleural lavage with saline before and after lung exeresis.We found 26.6% (40/150) positive cytologies in the pre and postoperative lavages in the first group. None were found in the control group." ] ] "bibliografia" => array:2 [ "titulo" => "Bibliografía" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:13 [ 0 => array:3 [ "identificador" => "bib0005" "etiqueta" => "1." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Actitud quirúrgica en el carcinoma broncopulmonar que se acompaña de un derrame pleural homolateral" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "A. Canto" 1 => "A. Arnau" 2 => "R. Guijarro" 3 => "A. Fernández" 4 => "M. Martorell" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Arch Bronconeumol" "fecha" => "1992" "volumen" => "28" "paginaInicial" => "332" "paginaFinal" => "336" ] ] ] ] ] ] 1 => array:3 [ "identificador" => "bib0010" "etiqueta" => "2." 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Archivos de Bronconeumología

ISSN: 0300-2896

Archivos de Bronconeumologia is an international journal that publishes original studies whose content is based upon results of research initiatives dealing with several aspects of respiratory medicine including epidemiology, respiratory physiology, pathophysiology of respiratory diseases, clinical management, thoracic surgery, pediatric lung diseases, respiratory critical care, respiratory allergy and basic research. Other types of articles such as editorials, reviews, and different types of letters are also published in the journal. Additionally, the journal expresses the voice of the following scientific societies: the Spanish Respiratory Society of Pneumology and Thoracic Surgery (SEPAR; https://www.separ.es/), the Latin American Thoracic Society (ALAT; https://alatorax.org/), and the Iberian American Association of Thoracic Surgery (AIACT; http://www.aiatorax.com/).

It is a monthly journal in which all manuscripts are sent to peer-review and handled by the editor or an associate editor from the team and the final decision is made on the basis of the comments from the expert reviewers and the editors. The journal is published solely in English. All the published data is composed of novel manuscripts not previously published in any other journal and not being in consideration for publication in any other journal..

The journal is indexed at Science Citation Index Expanded, Medline/Pubmed, Embase and SCOPUS. Access to any published article is possible through the journal's web page as well as from Pubmed, ScienceDirect, and other international databases. Furthermore, the journal is also present in X, Facebook and Linkedin. Manuscripts can be submitted electronically using the following web site: https://www.editorialmanager.com/ARBR/.

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Current Contents/Clinical Medicine, JCR SCI-Expanded, Index Medicus/Medline, Excerpta Medica/EMBASE, IBECS, IME, SCOPUS, IBECS

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8.7

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3.5

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0.464

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0.482

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