Valor pronóstico de la citología positiva hallada en el lavado pleural de pacientes con cáncer de pulmón. Estudio prospectivo
Prognostic value of positive findings of pleural lavage cytology in lung cancer patients. A prospective study
Servicios de Cirugía Torácica, Hospital General Universitario de Valencia
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"apellidos" => "Cantó Armengod" ] 2 => array:2 [ "nombre" => "E." "apellidos" => "Martín Díaz" ] ] "afiliaciones" => array:1 [ 0 => array:2 [ "entidad" => "Servicios de Cirugía Torácica, Hospital General Universitario de Valencia" "identificador" => "aff0005" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "1" "correspondencia" => "Correspondencia: Servicio de Cirugía Torácica. Hospital General Universitario de Valencia. Avda. de las Tres Cruces, s/n. 46014 Valencia." ] ] ] 1 => array:3 [ "autoresLista" => "R. Navarro Ibáñez, M. Ramón Capilla, R. García Aguado, M. Martorell Cebollada" "autores" => array:4 [ 0 => array:3 [ "nombre" => "R." "apellidos" => "Navarro Ibáñez" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">*</span>" "identificador" => "aff0010" ] ] ] 1 => array:3 [ "nombre" => "M." "apellidos" => "Ramón Capilla" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">*</span>" "identificador" => "aff0010" ] ] ] 2 => array:3 [ "nombre" => "R." "apellidos" => "García Aguado" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">**</span>" "identificador" => "aff0015" ] ] ] 3 => array:3 [ "nombre" => "M." "apellidos" => "Martorell Cebollada" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">***</span>" "identificador" => "aff0020" ] ] ] ] "afiliaciones" => array:3 [ 0 => array:3 [ "entidad" => "Servicios de Neumología, Hospital General Universitario de Valencia" "etiqueta" => "*" "identificador" => "aff0010" ] 1 => array:3 [ "entidad" => "Servicios de Ancstesia y Reanimación, Hospital General Universitario de Valencia" "etiqueta" => "**" "identificador" => "aff0015" ] 2 => array:3 [ "entidad" => "Servicios de Anatomía Patológica. Hospital General Universitario de Valencia" "etiqueta" => "***" "identificador" => "aff0020" ] ] ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Prognostic value of positive findings of pleural lavage cytology in lung cancer patients. A prospective study" ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "1995-06-15" "fechaAceptado" => "1996-01-30" "PalabrasClave" => array:2 [ "es" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palabras clave" "identificador" => "xpalclavsec546160" "palabras" => array:3 [ 0 => "Cáncer de pulmón" 1 => "Lavados pleurales" 2 => "Citología pleural" ] ] ] "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Key words" "identificador" => "xpalclavsec546161" "palabras" => array:3 [ 0 => "Lung cancer" 1 => "Pleural lavage" 2 => "Pleural cytology" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "es" => array:1 [ "resumen" => "<span id="abst0005" class="elsevierStyleSection elsevierViewall"><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Existe la posibilidad de que las neoplasias pulmonares puedan emitir células malignas a la cavidad pleural por distintos mecanismos. Esta posibilidad depende no sólo del tipo histológico, sino también del estadio clínico.</p><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Se analiza si la citología maligna hallada en el lavado pleural influye en la supervivencia y aparición de metástasis pleurales en su evolución postoperatoria.</p><p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">Presentamos una serie de 200 pacientes intervenidos quirúrgicamente en el Hospital General Universitario de Valencia desde el 1 de febrero de 1990 al 30 de marzo de 1993.</p><p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">Consta de dos grupos: el grupo primero está formado por 150 pacientes diagnosticados de cáncer de pulmón (CP), ninguno de los cuales tuvo derrame pleural previo ni sufrió punción transtorácica durante su estudio preoperatorio. Se excluyen de este grupo los pacientes tratados con quimioterapia (QT) o radioterapia (RT) neoadyuvantes, con el fin de evitar falsos positivos, y el grupo segundo o grupo testigo estaba formado por 50 pacientes sin patología tumoral a los que se realizó toracotomía por otras circunstancias.</p><p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">A todos ellos se les practicó lavados pleurales con suero fisiológico antes y después de las maniobras destinadas a la exéresis pulmonar.</p><p id="spar0030" class="elsevierStyleSimplePara elsevierViewall">Encontramos un 26,6% (40/150) de citologías positivas en la totalidad de lavados pre y posquirúrgicos del grupo primero. No encontramos citologías positivas en el grupo testigo.</p></span>" ] "en" => array:1 [ "resumen" => "<span id="abst0010" class="elsevierStyleSection elsevierViewall"><p id="spar0035" class="elsevierStyleSimplePara elsevierViewall">Pulmonary neoplasms can deposit malignant cells in the pleural cavity by a variety of mechanisms, depending not only on histological type but also on clinical stage.</p><p id="spar0040" class="elsevierStyleSimplePara elsevierViewall">We investigated the effect on survival rate of a finding of malignant cells in pleural lavage. We also investigated the effect of the presence of pleural metastasis on postoperative course of disease.</p><p id="spar0045" class="elsevierStyleSimplePara elsevierViewall">Two hundred surgical patients at Hospital General Universitario in Valencia between 1 February 1990 and 30 March 1993 were studied.</p><p id="spar0050" class="elsevierStyleSimplePara elsevierViewall">Two groups were formed. Group one: 150 patients with lung cancer, none of whom had had pleural effusion prior to suffering transthoracic puncture during the preoperative study. Patients treated with parallel chemotherapy or radiotherapy were excluded in order to circumvent false positives. Group two: 50 patients with no tumors who underwent thoracotomy for reasons other than lung cancer.</p><p id="spar0055" class="elsevierStyleSimplePara elsevierViewall">All patients underwent pleural lavage with saline before and after lung exeresis.</p><p id="spar0060" class="elsevierStyleSimplePara elsevierViewall">We found 26.6% (40/150) positive cytologies in the pre and postoperative lavages in the first group. None were found in the control group.</p></span>" ] ] "bibliografia" => array:2 [ "titulo" => "Bibliografía" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:13 [ 0 => array:3 [ "identificador" => "bib0005" "etiqueta" => "1." 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| 2020 June | 17 | 16 | 33 |
| 2020 May | 34 | 16 | 50 |
| 2020 April | 27 | 10 | 37 |
| 2020 March | 24 | 22 | 46 |
| 2020 February | 22 | 19 | 41 |
| 2020 January | 52 | 16 | 68 |
| 2019 December | 37 | 26 | 63 |
| 2019 November | 18 | 8 | 26 |
| 2019 October | 34 | 17 | 51 |
| 2019 September | 45 | 18 | 63 |
| 2019 August | 28 | 9 | 37 |
| 2019 July | 31 | 33 | 64 |
| 2019 June | 28 | 14 | 42 |
| 2019 May | 60 | 27 | 87 |
| 2019 April | 74 | 39 | 113 |
| 2019 March | 54 | 17 | 71 |
| 2019 February | 32 | 12 | 44 |
| 2019 January | 23 | 7 | 30 |
| 2018 December | 16 | 13 | 29 |
| 2018 November | 15 | 21 | 36 |
| 2018 October | 35 | 11 | 46 |
| 2018 September | 15 | 6 | 21 |
| 2018 May | 3 | 1 | 4 |
| 2018 April | 10 | 8 | 18 |
| 2018 March | 12 | 7 | 19 |
| 2018 February | 8 | 10 | 18 |
| 2018 January | 8 | 8 | 16 |
| 2017 December | 12 | 9 | 21 |
| 2017 November | 5 | 13 | 18 |
| 2017 October | 9 | 7 | 16 |
| 2017 September | 4 | 9 | 13 |
| 2017 August | 10 | 14 | 24 |
| 2017 July | 5 | 4 | 9 |
| 2017 June | 8 | 8 | 16 |
| 2017 May | 11 | 13 | 24 |
| 2017 April | 8 | 4 | 12 |
| 2017 March | 4 | 9 | 13 |
| 2017 February | 5 | 7 | 12 |
| 2017 January | 2 | 8 | 10 |
| 2016 December | 7 | 6 | 13 |
| 2016 November | 22 | 10 | 32 |
| 2016 October | 18 | 19 | 37 |
| 2016 September | 21 | 10 | 31 |
| 2016 August | 13 | 5 | 18 |
| 2016 July | 25 | 11 | 36 |
| 2016 June | 14 | 5 | 19 |
| 2016 May | 18 | 2 | 20 |
| 2016 April | 6 | 0 | 6 |
| 2016 March | 10 | 0 | 10 |
| 2016 February | 7 | 1 | 8 |
| 2016 January | 17 | 8 | 25 |
| 2015 December | 23 | 7 | 30 |
| 2015 November | 27 | 6 | 33 |
| 2015 October | 8 | 1 | 9 |
| 2015 September | 1 | 0 | 1 |
| 2015 June | 1 | 0 | 1 |
Show all
