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                          "autores" => array:2 [
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                        "paginaInicial" => "990"
                        "paginaFinal" => "992"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/7247607"
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                            2 => "J&#46; Rees"
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                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Br Med J"
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                        "paginaInicial" => "1&#46;605"
                        "paginaFinal" => "1&#46;606"
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                    ]
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                      "titulo" => "Computerized tomography in obstructive sleep apnea"
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                            3 => "R&#46;P&#46; Alien"
                            4 => "S&#46;M&#46; Goldman"
                            5 => "E&#46;R&#46; Bleecker"
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                    0 => array:2 [
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                        "tituloSerie" => "Am Rev Respir Dis"
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                        "paginaInicial" => "221"
                        "paginaFinal" => "226"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/6830039"
                            "web" => "Medline"
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                          "autores" => array:5 [
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                        "paginaInicial" => "487"
                        "paginaFinal" => "492"
                        "link" => array:1 [
                          0 => array:2 [
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                        "link" => array:1 [
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Vol. 32. Issue 10.
Pages 547-549 (December 1996)
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Vol. 32. Issue 10.
Pages 547-549 (December 1996)
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Síndrome de apneas obstructivas durante el sueño (SAOS) secundario a un linfoma faríngeo. Mejoría con tratamiento con presión continua de la vía aérea superior (CPAP)
Obstructive sleep apnea syndromes (OSAS) secondary to pharyngeal lymphoma
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G. Espinosa, A. Morelló
Hospital Clínic i Provincial. Facultad de Medicina. Universidad de Barcelona
A. Alarcón*, I. Vilaseca**, J.R. Ayuso***, J.M. Montserrat*,1
* Servicios de Neumología y Alergia Respiratoria, Hospital Clínic i Provincial. Facultad de Medicina. Universidad de Barcelona
** Servicios de Otorrinolaringología, Hospital Clínic i Provincial. Facultad de Medicina. Universidad de Barcelona
*** Servicios de Radiodiagnóstico. Hospital Clínic i Provincial. Facultad de Medicina. Universidad de Barcelona
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La apnea obstructiva del sueño (SAOS) es un síndrome caracterizado por la presencia de múltiples episodios de obstrucción de las vías aéreas superiores (VAS) durante el sueño. Durante el día, los pacientes aquejan hipersomnia, embotamiento y falta de concentración que se acompañan, característicamente, de ronquidos nocturnos.

Se presenta el caso de un paciente afectado de linfoma de Hodgkin sin remisión completa y recidiva faríngea que provocaba un SAOS. Clínicamente, presentaba somnolencia diurna muy acusada, acompañada de trastornos de conducta. Entre las exploraciones complementarias destacaban unas asas de flujo-volumen, indicativas de inestabilidad de la VAS. Una TAC cervical mostró una masa prevertebral linfomatosa faríngea, que producía una reducción acusada del área de la VAS. Ésta aumentó considerablemente de tamaño tras la aplicación de presión continua positiva (CPAP) en la VAS, lo que normalizó el sueño y provocó una mejoría importante de la clínica del paciente. Posteriormente y tras la quimioterapia, desapareció el SAOS y el paciente pudo abandonar el tratamiento con CPAP.

Palabras clave:
Síndrome de apneas obstructivas del sueño (SAOS)
Linfoma faríngeo
Presión positiva continua de la vía aérea (CPAP)

Obstructive sleep apnea syndrome (OSAS) is characterized by multiple episodes of upper airway (UA) obstruction during sleep. Patients experience daytime hypersomnia, sluggishness and inability to concentrate; snoring at night is common.

We report the case of a man with Hodgkin's lymphoma without full remission and with pharyngeal recidivism leading to OSAS. He experienced marked diurnal hypersomnia accompanied by behavior disorders. Examination revealed flow-volume OSAS, suggesting UA instability. Cervical computed tomography showed a prevertebral lymphomatous mass in the pharynx causing significant UA compression. UA size increased considerably after use of continuous positive airway pressure (CPAP), which normalized sleep and produced significant relief of symptoms. Later, after chemotherapy, OSAS resolved and the patient was able to abandon CPAP treatment.

Key words:
Obstructive sleep apnea syndrome (OSAS)
Pharyngeal lymphoma
Continuous positive airway pressure (CPAP)
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Bibliografía
[1.]
C. Guilleminault, W.C. Dement.
Sleep apnea syndromes.
Nueva York: Alan Liss Inc., (1978),
[2.]
V. Hoffstein, N. Zamel, E.A. Phillipson.
Long volumes dependence of pharyngeal cross-sectorial area in patients with obstructive sleep apnea.
Am Rev Respir Dis, 130 (1984), pp. 175-178
[3.]
I.G. Brown, T.D. Bradley, E.A. Phillipson, N. Zamel, V. Hoffstein.
Pharyngeal compliance in snoring subjects with and without obstructive sleep apnea.
Am Rev Res Dis, 132 (1988), pp. 211-215
[4.]
I.B. Brown, P.A. McClean, R. Broucher, N. Zamel, V. Hoffstein.
Changes in pharyngeal cross-sectional area with posture and application of continuous positive airway pressure in patients with obstructive sleep apnea.
Am Rev Respir Dis, 136 (1987), pp. 628-663
[5.]
B. Langevin, F. Sukkar, P. Leger, A. Guez, D. Robert.
Sleep apnea syndrome (SAS) of specific etiology: review and incidence from a sleep laboratory.
Sleep, 15 (1992), pp. 25-32
[6.]
C.E. Sullivan, F.G. Issa, M. Berthon-Jones, L. Eves.
Reversal of obstructive sleep apnea by continuous positive airway pressure through the nares.
Lancet, 1 (1981), pp. 862-865
[7.]
C.E. Sullivan, F.G. Issa, M. Berthon-Jones, V.B. McCauley, L.V.J. Costas.
Home treatment of obstructive sleep apnea with continuous positive airway pressure applied through a nose-mask.
Buil Eur Physiopathol Respir, 20 (1984), pp. 49-54
[8.]
J. He, M.H. Kryger, F.J. Zorick, W. Conway, T. Roth.
Mortality and apnea Índex in obstructive sleep apnea: experience in 385 male patients.
Chest, 94 (1988), pp. 9-14
[9.]
C.M. Carr.
Non-Hodgkin's lymphoma presenting initially as a sleep-apnea syndrome.
Ala Med Jul, 57 (1987), pp. 28-29
[10.]
F. Zorick, T. Roth, M. Kramer, H. Flessa.
Exacerbation of upper-airway sleep apnea by lymphocytic lymphoma.
Chest, 77 (1988), pp. 689-690
[11.]
W.C. Orr, R.J. Martin.
Obstructive sleep apnea associated with tonsillar hypertrophy in adults.
Arch Intern Med, 141 (1981), pp. 990-992
[12.]
M. King, M. Gleeson, J. Rees.
Obstructive sleep apnea and tonsillar lymphoma.
Br Med J, 294 (1987), pp. 1.605-1.606
[13.]
E.F. Haponik, P.L. Smith, M.E. Bohlman, R.P. Alien, S.M. Goldman, E.R. Bleecker.
Computerized tomography in obstructive sleep apnea.
Am Rev Respir Dis, 127 (1983), pp. 221-226
[14.]
P.M. Surratt, P. Dee, R.L. Atkinson, P. Armstrong, S.C. Nilhoit.
Fluoroscopic and computed tomographic features of the pharyngeal airway in obstructive sleep apnea.
Am Rev Respir Dis, 127 (1983), pp. 487-492
[15.]
S.T. Kuna, D.G. Bedi, C. Ryckman.
Effect of nasal airway positive pressure on upper airway size and configuration.
Am Rev Respir Dis, 138 (1988), pp. 969-997
Copyright © 1996. Sociedad Española de Neumología y Cirugía Torácica
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