Journal Information
Vol. 61. Issue 5.
Pages 274-281 (May 2025)
Share
Download PDF
More article options
Vol. 61. Issue 5.
Pages 274-281 (May 2025)
Original Article
Regional Disparities and Trends in Venous Thromboembolism Mortality in Spain (1999–2022)
Visits
1718
Lucia Cayuelaa, Anna Michela Gaetab,
Corresponding author
annamichelagaeta@hotmail.it

Corresponding author.
, Remedios Oteroc,d,e, Luis Jara-Palomaresc,d,e, Isabel Mendo Pedrajasa, Aurelio Cayuelaf
a Department of Internal Medicine, Hospital Universitario Severo Ochoa, Leganés, Spain
b Pulmonology Department, Hospital Universitario Severo Ochoa, Leganés, Spain
c Medical Surgical Unit of Respiratory Diseases, Hospital Universitario Virgen del Rocío, Seville, Spain
d Instituto de Biomedicina de Sevilla (IBiS), Consejo Superior de Investigaciones Cientificas (CSIC), Universidad de Sevilla, Sevilla, Spain
e Centro de Investigación Biomédica en Red de Enfermedades Respiratorias (CIBERES), Instituto de Salud Carlos III, Madrid, Spain
f Unit of Public Health, Prevention and Health Promotion, South Seville Health Management Area, Seville, Spain
This item has received
Article information
Abstract
Full Text
Bibliography
Download PDF
Statistics
Figures (3)
Show moreShow less
Tables (4)
Table 1. Age-Standardised Mortality Rates (ASMR) for Venous Thromboembolism by Sex and Age, Across Autonomous Communities in Spain (1999 and 2022).
Tables
Table 2. Joinpoint Analysis Results for Venous Thromboembolism Mortality in Spain (1999–2022) by Sex and Age Groups (All Ages), Across Autonomous Communities.
Tables
Table 3. Joinpoint Analysis Results for Venous Thromboembolism Mortality in Spain (1999–2022) by Sex and Age Group (<65), Across Autonomous Communities.
Tables
Table 4. Joinpoint Analysis Results for Venous Thromboembolism Mortality in Spain (1999–2022) by Sex and Age Group (65+), Across Autonomous Communities.
Tables
Show moreShow less
Abstract
Aim

This study aims to analyze trends in venous thromboembolism (VTE) mortality in the Spanish Autonomous Communities (ACs) from 1999 to 2022, with a focus on identifying regional disparities and informing targeted public health interventions.

Methods

Age-standardized mortality rates (ASMRs) were calculated using the European standard population as a reference. Joinpoint regression analysis was employed to identify significant changes in mortality trends, and geographical analysis was conducted using Bayesian inference to assess regional variations in mortality risk.

Results

From 1999 to 2022, Spain recorded 59,515 VTE-related deaths, with a higher proportion in women (59.4%) compared to men (40.6%). On a nationwide scale, VTE ASMRs showed a general decline for both men and women, with rates decreasing from 11.0 to 5.1 per 100,000 in men and from 9.2 to 4.4 per 100,000 in women. However, this decline was not uniform across all regions or demographic groups. Notably, mortality rates among younger individuals, particularly men, increased during the study period, highlighting the need for targeted interventions. Analysis revealed significant regional disparities, with higher mortality risks observed in Extremadura, Aragon, Navarre, and Andalusia, particularly for women.

Conclusions

This study provides valuable insights into the complex landscape of VTE mortality in Spain. While the overall decline in mortality is encouraging, persistent regional disparities and rising rates among younger individuals underscore the need for ongoing surveillance and targeted interventions.

Keywords:
Venous thromboembolism
Deep vein thrombosis
Pulmonary embolism
Mortality trends
Spain
Regional disparities
Public health
Graphical abstract

Article

These are the options to access the full texts of the publication Archivos de Bronconeumología
Member
If you are a member of SEPAR:
  • Go to >>>SEPAR<<< website and sign in.
Subscriber
Subscriber

If you already have your login data, please click here .

If you have forgotten your password you can you can recover it by clicking here and selecting the option “I have forgotten my password”
Purchase
Purchase article

Purchasing article the PDF version will be downloaded

Purchase now
Contact
Phone for subscriptions and reporting of errors
From Monday to Friday from 9 a.m. to 6 p.m. (GMT + 1) except for the months of July and August which will be from 9 a.m. to 3 p.m.
Calls from Spain
932 415 960
Calls from outside Spain
+34 932 415 960
Email
Archivos de Bronconeumología
Article options
Tools

Are you a health professional able to prescribe or dispense drugs?