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=> array:2 [ "doi" => "10.1164/ajrccm.161.supplement_3.ats600" "Revista" => array:6 [ "tituloSerie" => "Am J Respir Crit Care Med" "fecha" => "2000" "volumen" => "161" "paginaInicial" => "S221" "paginaFinal" => "SS47" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10764341" "web" => "Medline" ] ] ] ] ] ] ] ] 2 => array:3 [ "identificador" => "bib3" "etiqueta" => "3" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "New insights on the nature of latent tuberculosis infection and its treatment" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "PJ Cardona" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Inflamm Allergy Drug Targets" "fecha" => "2007" "volumen" => "6" "paginaInicial" => "27" "paginaFinal" => "39" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/17352686" "web" => "Medline" ] ] ] ] ] ] ] ] 3 => array:3 [ "identificador" => "bib4" "etiqueta" => "4" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Dormancy of <span class="elsevierStyleItalic">Mycobacterium tuberculosis</span> and latency of disease" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "LG Wayne" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Eur J Clin Microbiol Infect Dis" "fecha" => "1994" "volumen" => "13" "paginaInicial" => "908" "paginaFinal" => "914" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/7698116" "web" => "Medline" ] ] ] ] ] ] ] ] 4 => array:3 [ "identificador" => "bib5" "etiqueta" => "5" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Immunophysiology and immunopathology of tuberculosis" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "JM Grange" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "LibroEditado" => array:4 [ "titulo" => "Clinical tuberculosis" "paginaInicial" => "113" "paginaFinal" => "127" "serieFecha" => "1998" ] ] ] ] ] ] 5 => array:3 [ "identificador" => "bib6" "etiqueta" => "6" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "New insights into the function of granulomas in human tuberculosis" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "T Ulrichs" 1 => "SH Kaufmann" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1002/path.1906" "Revista" => array:7 [ "tituloSerie" => "J Pathol" "fecha" => "2006" "volumen" => "208" "paginaInicial" => "261" "paginaFinal" => "269" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16362982" "web" => "Medline" ] ] "itemHostRev" => array:3 [ "pii" => "S0001731011001396" "estado" => "S300" "issn" => "00017310" ] ] ] ] ] ] ] 6 => array:3 [ "identificador" => "bib7" "etiqueta" => "7" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Preclinical candidates and targets for tuberculosis therapy" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "CE Barry III" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Curr Opin Investig Drugs" "fecha" => "2001" "volumen" => "2" "paginaInicial" => "198" "paginaFinal" => "201" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11816829" "web" => "Medline" ] ] ] ] ] ] ] ] 7 => array:3 [ "identificador" => "bib8" "etiqueta" => "8" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Periodontal disease as a specific, albeit chronic, infection: diagnosis and treatment" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "WJ Loesche" 1 => "NS Grossman" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1128/CMR.14.4.727-752.2001" "Revista" => array:6 [ "tituloSerie" => "Clin Microbiol Rev" "fecha" => "2001" "volumen" => "14" "paginaInicial" => "727" "paginaFinal" => "752" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11585783" "web" => "Medline" ] ] ] ] ] ] ] ] 8 => array:3 [ "identificador" => "bib9" "etiqueta" => "9" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Host-bacterial mutualism in the human intestine" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "F Backhed" 1 => "RE Ley" 2 => "JL Sonnenburg" 3 => "DA Peterson" 4 => "JI Gordon" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1126/science.1104816" "Revista" => array:6 [ "tituloSerie" => "Science" "fecha" => "2005" "volumen" => "307" "paginaInicial" => "1915" "paginaFinal" => "1920" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15790844" "web" => "Medline" ] ] ] ] ] ] ] ] 9 => array:3 [ "identificador" => "bib10" "etiqueta" => "10" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Formation and resuscitation of “nonculturable” cells of Rhodococcus rhodochrous and <span class="elsevierStyleItalic">Mycobacterium tuberculosis</span> in prolonged stationary phase" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "MO Shleeva" 1 => "K Bagramyan" 2 => "MV Telkov" 3 => "GV Mukamolova" 4 => "M Young" 5 => "DB Kell" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1099/00221287-148-5-1581" "Revista" => array:6 [ "tituloSerie" => "Microbiology" "fecha" => "2002" "volumen" => "148" "paginaInicial" => "1581" "paginaFinal" => "1591" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11988533" "web" => "Medline" ] ] ] ] ] ] ] ] 10 => array:3 [ "identificador" => "bib11" "etiqueta" => "11" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Molecular and cellular processing of lung surfactant" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "SA Rooney" 1 => "SL Young" 2 => "CR Mendelson" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Faseb J" "fecha" => "1994" "volumen" => "8" "paginaInicial" => "957" "paginaFinal" => "967" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8088461" "web" => "Medline" ] ] ] ] ] ] ] ] 11 => array:3 [ "identificador" => "bib12" "etiqueta" => "12" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Survival of <span class="elsevierStyleItalic">Mycobacterium avium</span> and <span class="elsevierStyleItalic">Mycobacterium tuberculosis</span> in acidified vacuoles of murine macrophages" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "MS Gomes" 1 => "S Paul" 2 => "AL Moreira" 3 => "R Appelberg" 4 => "M Rabinovitch" 5 => "G Kaplan" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Infect Immun" "fecha" => "1999" "volumen" => "67" "paginaInicial" => "3199" "paginaFinal" => "3206" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10377091" "web" => "Medline" ] ] ] ] ] ] ] ] 12 => array:3 [ "identificador" => "bib13" "etiqueta" => "13" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The cellular immunological aspects of the granulomatous response" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "DL Boros" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "LibroEditado" => array:5 [ "paginaInicial" => "1" "paginaFinal" => "20" "serieVolumen" => "Vol. 1" "serieTitulo" => "Granulomatous infections and inflammations. Cellular and molecular mechanisms" "serieFecha" => "2003" ] ] ] ] ] ] 13 => array:3 [ "identificador" => "bib14" "etiqueta" => "14" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "<span class="elsevierStyleItalic">Mycobacterium bovis</span> bacillus Calmette-Guerin induces TLR2-mediated formation of lipid bodies: intracellular domains for eicosanoid synthesis in vivo" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "H D'Avila" 1 => "RC Melo" 2 => "GG Parreira" 3 => "E Werneck-Barroso" 4 => "HC Castro-Faria-Neto" 5 => "PT Bozza" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "J Immunol" "fecha" => "2006" "volumen" => "176" "paginaInicial" => "3087" "paginaFinal" => "3097" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16493068" "web" => "Medline" ] ] ] ] ] ] ] ] 14 => array:3 [ "identificador" => "bib15" "etiqueta" => "15" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Host responses and antigens involved in protective immunity to <span class="elsevierStyleItalic">Mycobacterium tuberculosis</span>" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "P Andersen" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Scand J Immunol" "fecha" => "1997" "volumen" => "45" "paginaInicial" => "115" "paginaFinal" => "131" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9042423" "web" => "Medline" ] ] ] ] ] ] ] ] 15 => array:3 [ "identificador" => "bib16" "etiqueta" => "16" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Widespread bronchogenic dissemination makes DBA/2 mice more susceptible than C57BL/6 mice to experimental aerosol infection with <span class="elsevierStyleItalic">Mycobacterium tuberculosis.</span>" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "PJ Cardona" 1 => "S Gordillo" 2 => "J Díaz" 3 => "G Tapia" 4 => "I Amat" 5 => "A Pallarés" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Infect Immun" "fecha" => "2003" "volumen" => "71" "paginaInicial" => "5845" "paginaFinal" => "5854" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/14500506" "web" => "Medline" ] ] ] ] ] ] ] ] 16 => array:3 [ "identificador" => "bib17" "etiqueta" => "17" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Low concentrations of nitric oxide exert a hormetic effect on <span class="elsevierStyleItalic">Mycobacterium tuberculosis</span> in vitro" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "WB Brugmann" 1 => "MA Firmani" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1128/JCM.43.9.4844-4846.2005" "Revista" => array:6 [ "tituloSerie" => "J Clin Microbiol" "fecha" => "2005" "volumen" => "43" "paginaInicial" => "4844" "paginaFinal" => "4846" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16145155" "web" => "Medline" ] ] ] ] ] ] ] ] 17 => array:3 [ "identificador" => "bib18" "etiqueta" => "18" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Regulation of T-cell activation in the lung: alveolar macrophages induce reversible T-cell anergy in vitro associated with inhibition of interleukin-2 receptor signal transduction" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "D Strickland" 1 => "UR Kees" 2 => "PG Holt" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Immunology" "fecha" => "1996" "volumen" => "87" "paginaInicial" => "250" "paginaFinal" => "258" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8698387" "web" => "Medline" ] ] ] ] ] ] ] ] 18 => array:3 [ "identificador" => "bib19" "etiqueta" => "19" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Evaluation of human monocyte function in vitro" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "P Roth" 1 => "A Celada" 2 => "A Cruchaud" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Ann Immunol (Paris)" "fecha" => "1979" "volumen" => "130C" "paginaInicial" => "611" "paginaFinal" => "620" ] ] ] ] ] ] 19 => array:3 [ "identificador" => "bib20" "etiqueta" => "20" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Foamy macrophages within lung granulomas of mice infected with Mycobacterium tuberculosis express molecules characteristic of dendritic cells and antiapoptotic markers of the TNF receptor-associated factor family" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "D Ordway" 1 => "M Henao-Tamayo" 2 => "IM Orme" 3 => "M González-Juarrero" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "J Immunol" "fecha" => "2005" "volumen" => "175" "paginaInicial" => "3873" "paginaFinal" => "3881" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16148133" "web" => "Medline" ] ] ] ] ] ] ] ] 20 => array:3 [ "identificador" => "bib21" "etiqueta" => "21" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The heat resistance of tubercle bacilli in the lungs of infected mice" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "JG Wallace" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1164/arrd.1961.83.6.866" "Revista" => array:7 [ "tituloSerie" => "Am Rev Respir Dis" "fecha" => "1961" "volumen" => "83" "paginaInicial" => "866" "paginaFinal" => "871" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/13782801" "web" => "Medline" ] ] "itemHostRev" => array:3 [ "pii" => "S0735109707037771" "estado" => "S300" "issn" => "07351097" ] ] ] ] ] ] ] 21 => array:3 [ "identificador" => "bib22" "etiqueta" => "22" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Modeling bronchial circulation with application to soluble gas exchange: description and sensitivity analysis" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "TD Bui" 1 => "D Dabdub" 2 => "SC George" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "J Appl Physiol" "fecha" => "1998" "volumen" => "84" "paginaInicial" => "2070" "paginaFinal" => "2088" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9609803" "web" => "Medline" ] ] ] ] ] ] ] ] 22 => array:3 [ "identificador" => "bib23" "etiqueta" => "23" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:1 [ "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "HL Rieder" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Libro" => array:4 [ "titulo" => "Epidemiologic basis of tuberculosis control" "fecha" => "1999" "editorial" => "International Union Against Tuberculosis and Lund Disease" "editorialLocalizacion" => "Paris" ] ] ] ] ] ] 23 => array:3 [ "identificador" => "bib24" "etiqueta" => "24" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Intracellular lipophilic inclusions of mycobacteria in vitro and in sputum" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "NJ Garton" 1 => "H Christensen" 2 => "DE Minnikin" 3 => "RA Adegbola" 4 => "MR Barer" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1099/00221287-148-10-2951" "Revista" => array:6 [ "tituloSerie" => "Microbiology" "fecha" => "2002" "volumen" => "148" "paginaInicial" => "2951" "paginaFinal" => "2958" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12368428" "web" => "Medline" ] ] ] ] ] ] ] ] 24 => array:3 [ "identificador" => "bib25" "etiqueta" => "25" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "On the nature of <span class="elsevierStyleItalic">Mycobacterium tuberculosis</span>-latent bacilli" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "PJ Cardona" 1 => "J Ruiz-Manzano" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1183/09031936.04.00072604" "Revista" => array:6 [ "tituloSerie" => "Eur Respir J" "fecha" => "2004" "volumen" => "24" "paginaInicial" => "1044" "paginaFinal" => "1051" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15572551" "web" => "Medline" ] ] ] ] ] ] ] ] 25 => array:3 [ "identificador" => "bib26" "etiqueta" => "26" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The impact of altitude on mortality from tuberculosis and pneumonia" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "R Pérez-Padilla" 1 => "F Franco-Marina" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Int J Tuberc Lung Dis" "fecha" => "2004" "volumen" => "8" "paginaInicial" => "1315" "paginaFinal" => "1320" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15581198" "web" => "Medline" ] ] ] ] ] ] ] ] 26 => array:3 [ "identificador" => "bib27" "etiqueta" => "27" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Effect of altitude on the frequency of pulmonary tuberculosis" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "MH Vargas" 1 => "ME Furuya" 2 => "C Pérez-Guzmán" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Int J Tuberc Lung Dis" "fecha" => "2004" "volumen" => "8" "paginaInicial" => "1321" "paginaFinal" => "1324" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15581199" "web" => "Medline" ] ] ] ] ] ] ] ] 27 => array:3 [ "identificador" => "bib28" "etiqueta" => "28" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Production of antibodies against glycolipids from the <span class="elsevierStyleItalic">Mycobacterium tuberculosis</span> cell wall in aerosol murine models of tuberculosis" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "PJ Cardona" 1 => "E Julián" 2 => "X Valles" 3 => "S Gordillo" 4 => "M Muñoz" 5 => "M Luquin" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Scand J Immunol" "fecha" => "2002" "volumen" => "55" "paginaInicial" => "639" "paginaFinal" => "645" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12028568" "web" => "Medline" ] ] ] ] ] ] ] ] 28 => array:3 [ "identificador" => "bib29" "etiqueta" => "29" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Immunotherapy with fragmented <span class="elsevierStyleItalic">Mycobacterium tuberculosis</span> cells increases the effectiveness of chemotherapy against a chronical infection in a murine model of tuberculosis" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "PJ Cardona" 1 => "I Amat" 2 => "S Gordillo" 3 => "V Arcos" 4 => "E Guirado" 5 => "J Díaz" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/j.vaccine.2004.09.008" "Revista" => array:7 [ "tituloSerie" => "Vaccine" "fecha" => "2005" "volumen" => "23" "paginaInicial" => "1393" "paginaFinal" => "1398" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15661388" "web" => "Medline" ] ] "itemHostRev" => array:3 [ "pii" => "S0140673606688454" "estado" => "S300" "issn" => "01406736" ] ] ] ] ] ] ] 29 => array:3 [ "identificador" => "bib30" "etiqueta" => "30" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "RUTI: a new chance to shorten the treatment of latent tuberculosis infection" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "PJ Cardona" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Tuberculosis (Edinb)" "fecha" => "2006" "volumen" => "86" "paginaInicial" => "273" "paginaFinal" => "289" ] ] ] ] ] ] 30 => array:3 [ "identificador" => "bib31" "etiqueta" => "31" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Origen y desarrollo de RUTI, una nueva vacuna terapéutica contra la infección por <span class="elsevierStyleItalic">Mycobacterium tuberculosis</span>" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 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Journal Information
Vol. 43. Issue 11.
Pages 591-593 (January 2007)
Vol. 43. Issue 11.
Pages 591-593 (January 2007)
Editorial
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Therapeutic Vaccines Against Tuberculosis: A Glowing Future
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Pere-Joan Cardona
Corresponding author
pjcardona.igtp.germanstrias@gencat.net
Correspondence: Dr. P.J. Cardona. Unitat de Tuberculosi Experimental, Institut per a la Investigació en Ciències de la Salut Germans Trias i Pujol. Ctra. del Canyet, s/n. 08916 Badalona. Barcelona. España
Correspondence: Dr. P.J. Cardona. Unitat de Tuberculosi Experimental, Institut per a la Investigació en Ciències de la Salut Germans Trias i Pujol. Ctra. del Canyet, s/n. 08916 Badalona. Barcelona. España
Unitat de Tuberculosi Experimental, Servei de Microbiologia, Fundació Institut per a la Investigació en Ciències de la Salut Germans Trias i Pujol, Universitat Autònoma de Barcelona, Badalona, Barcelona, Spain
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References
[1]
World Health Organization.
Global tuberculosis control: surveillance, planning, financing, WHO, (2006),
[2]
American Thoracic Society and the Centers for Disease Control and Prevention.
Am J Respir Crit Care Med, 161 (2000), pp. S221-SS47
[3]
PJ Cardona.
New insights on the nature of latent tuberculosis infection and its treatment.
Inflamm Allergy Drug Targets, 6 (2007), pp. 27-39
[4]
LG Wayne.
Dormancy of Mycobacterium tuberculosis and latency of disease.
Eur J Clin Microbiol Infect Dis, 13 (1994), pp. 908-914
[5]
JM Grange.
Immunophysiology and immunopathology of tuberculosis.
Clinical tuberculosis, pp. 113-127
[6]
T Ulrichs, SH Kaufmann.
New insights into the function of granulomas in human tuberculosis.
J Pathol, 208 (2006), pp. 261-269
[7]
CE Barry III.
Preclinical candidates and targets for tuberculosis therapy.
Curr Opin Investig Drugs, 2 (2001), pp. 198-201
[8]
WJ Loesche, NS Grossman.
Periodontal disease as a specific, albeit chronic, infection: diagnosis and treatment.
Clin Microbiol Rev, 14 (2001), pp. 727-752
[9]
F Backhed, RE Ley, JL Sonnenburg, DA Peterson, JI Gordon.
Host-bacterial mutualism in the human intestine.
Science, 307 (2005), pp. 1915-1920
[10]
MO Shleeva, K Bagramyan, MV Telkov, GV Mukamolova, M Young, DB Kell, et al.
Formation and resuscitation of “nonculturable” cells of Rhodococcus rhodochrous and Mycobacterium tuberculosis in prolonged stationary phase.
Microbiology, 148 (2002), pp. 1581-1591
[11]
SA Rooney, SL Young, CR Mendelson.
Molecular and cellular processing of lung surfactant.
Faseb J, 8 (1994), pp. 957-967
[12]
MS Gomes, S Paul, AL Moreira, R Appelberg, M Rabinovitch, G Kaplan.
Survival of Mycobacterium avium and Mycobacterium tuberculosis in acidified vacuoles of murine macrophages.
Infect Immun, 67 (1999), pp. 3199-3206
[13]
DL Boros.
The cellular immunological aspects of the granulomatous response.
pp. 1-20
[14]
H D'Avila, RC Melo, GG Parreira, E Werneck-Barroso, HC Castro-Faria-Neto, PT Bozza.
Mycobacterium bovis bacillus Calmette-Guerin induces TLR2-mediated formation of lipid bodies: intracellular domains for eicosanoid synthesis in vivo.
J Immunol, 176 (2006), pp. 3087-3097
[15]
P Andersen.
Host responses and antigens involved in protective immunity to Mycobacterium tuberculosis.
Scand J Immunol, 45 (1997), pp. 115-131
[16]
PJ Cardona, S Gordillo, J Díaz, G Tapia, I Amat, A Pallarés, et al.
Widespread bronchogenic dissemination makes DBA/2 mice more susceptible than C57BL/6 mice to experimental aerosol infection with Mycobacterium tuberculosis..
Infect Immun, 71 (2003), pp. 5845-5854
[17]
WB Brugmann, MA Firmani.
Low concentrations of nitric oxide exert a hormetic effect on Mycobacterium tuberculosis in vitro.
J Clin Microbiol, 43 (2005), pp. 4844-4846
[18]
D Strickland, UR Kees, PG Holt.
Regulation of T-cell activation in the lung: alveolar macrophages induce reversible T-cell anergy in vitro associated with inhibition of interleukin-2 receptor signal transduction.
Immunology, 87 (1996), pp. 250-258
[19]
P Roth, A Celada, A Cruchaud.
Evaluation of human monocyte function in vitro.
Ann Immunol (Paris), 130C (1979), pp. 611-620
[20]
D Ordway, M Henao-Tamayo, IM Orme, M González-Juarrero.
Foamy macrophages within lung granulomas of mice infected with Mycobacterium tuberculosis express molecules characteristic of dendritic cells and antiapoptotic markers of the TNF receptor-associated factor family.
J Immunol, 175 (2005), pp. 3873-3881
[21]
JG Wallace.
The heat resistance of tubercle bacilli in the lungs of infected mice.
Am Rev Respir Dis, 83 (1961), pp. 866-871
[22]
TD Bui, D Dabdub, SC George.
Modeling bronchial circulation with application to soluble gas exchange: description and sensitivity analysis.
J Appl Physiol, 84 (1998), pp. 2070-2088
[23]
HL Rieder.
Epidemiologic basis of tuberculosis control, International Union Against Tuberculosis and Lund Disease, (1999),
[24]
NJ Garton, H Christensen, DE Minnikin, RA Adegbola, MR Barer.
Intracellular lipophilic inclusions of mycobacteria in vitro and in sputum.
Microbiology, 148 (2002), pp. 2951-2958
[25]
PJ Cardona, J Ruiz-Manzano.
On the nature of Mycobacterium tuberculosis-latent bacilli.
Eur Respir J, 24 (2004), pp. 1044-1051
[26]
R Pérez-Padilla, F Franco-Marina.
The impact of altitude on mortality from tuberculosis and pneumonia.
Int J Tuberc Lung Dis, 8 (2004), pp. 1315-1320
[27]
MH Vargas, ME Furuya, C Pérez-Guzmán.
Effect of altitude on the frequency of pulmonary tuberculosis.
Int J Tuberc Lung Dis, 8 (2004), pp. 1321-1324
[28]
PJ Cardona, E Julián, X Valles, S Gordillo, M Muñoz, M Luquin, et al.
Production of antibodies against glycolipids from the Mycobacterium tuberculosis cell wall in aerosol murine models of tuberculosis.
Scand J Immunol, 55 (2002), pp. 639-645
[29]
PJ Cardona, I Amat, S Gordillo, V Arcos, E Guirado, J Díaz, et al.
Immunotherapy with fragmented Mycobacterium tuberculosis cells increases the effectiveness of chemotherapy against a chronical infection in a murine model of tuberculosis.
Vaccine, 23 (2005), pp. 1393-1398
[30]
PJ Cardona.
RUTI: a new chance to shorten the treatment of latent tuberculosis infection.
Tuberculosis (Edinb), 86 (2006), pp. 273-289
[32]
E Guirado, I Amat, O Gil, J Díaz, V Arcos, N Cáceres, et al.
Passive serum therapy with polyclonal antibodies against Mycobacterium tuberculosis protects against post-chemotherapy relapse of tuberculosis infection in SCID mice.
Microbes Infect, 8 (2006), pp. 1252-1259
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