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        "resumen" => "<span class="elsevierStyleSectionTitle">OBJECTIVE</span><p class="elsevierStyleSimplePara elsevierViewall">The aim of this study was to assess the results of smoking cessation therapy in a specialist unit by calculating the probability of continued abstinence at 6-month follow-up and analyzing differences according to the characteristics of the individuals&#46;</p> <span class="elsevierStyleSectionTitle">PATIENTS AND METHODS</span><p class="elsevierStyleSimplePara elsevierViewall">A prospective longitudinal study was undertaken in smokers who received multicomponent smoking-cessation therapy over a period of 3 months&#46; Continued abstinence was assessed on the basis of self-report by participants and confirmed by measurement of exhaled carbon monoxide levels&#46; Kaplan-Meier survival analysis was performed to assess the probability of continued abstinence&#46; Log-rank tests were used to analyze differences in continued abstinence according to different qualitative variables&#46;</p> <span class="elsevierStyleSectionTitle">RESULTS</span><p class="elsevierStyleSimplePara elsevierViewall">The 1120 patients who participated in the study &#40;56&#37;men and 44&#37;women&#41; had a mean &#40;SD&#41; age of 44&#46;1 &#40;9&#46;5&#41; years&#46; The mean score on the Fagerstr&#246;m test was 6&#46;3 &#40;2&#46;1&#41;&#46;Nicotine replacement therapy was provided in 70&#46;8&#37;of patients while 29&#46;2&#37;received bupropion&#46; The probability of continued abstinence at 6 months was 62&#46;2&#37;&#46; Individuals with a high dependence had a lower probability of continued abstinence at 6 months&#44; as did those in whom treatment adherence was poor&#46; No differences were observed in the probability of abstinence according to sex or type of pharmacological treatment&#46;</p> <span class="elsevierStyleSectionTitle">CONCLUSIONS</span><p class="elsevierStyleSimplePara elsevierViewall">Individuals with a high nicotine dependence can benefit from intensive smoking-cessation treatment in a specialist unit to achieve continued abstinence&#46;</p>"
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        "resumen" => "<span class="elsevierStyleSectionTitle">OBJETIVO</span><p class="elsevierStyleSimplePara elsevierViewall">Valorar los resultados del tratamiento del tabaquismo en una unidad especializada&#44; mediante el c&#225;lculo de la probabilidad de permanecer abstinente a los 6 meses del seguimiento&#44; y analizar las diferencias existentes seg&#250;n las caracter&#237;sticas de los individuos&#46;</p> <span class="elsevierStyleSectionTitle">PACIENTES Y M&#201;TODOS</span><p class="elsevierStyleSimplePara elsevierViewall">Se ha realizado un estudio anal&#237;tico prospectivo y longitudinal entre los fumadores que recibieron tratamiento multicomponente durante 3 meses&#46; Se consider&#243; la abstinencia continuada mediante la declaraci&#243;n de los propios participantes&#44; confirmada con cooximetr&#237;a&#46; Se realiz&#243; un an&#225;lisis de supervivencia por el m&#233;todo de Kaplan-Meier&#46; Se aplicaron contrastes de rangos logar&#237;tmicos para estudiar las diferencias en la abstinencia continuada de los pacientes para las distintas categor&#237;as de las variables cualitativas&#46;</p> <span class="elsevierStyleSectionTitle">RESULTADOS</span><p class="elsevierStyleSimplePara elsevierViewall">Se estudi&#243; a 1&#46;120 pacientes &#40;un 56&#37;varones y el 44&#37;mujeres&#41;&#44; con una edad media &#40;&#177;desviaci&#243;n est&#225;ndar de 44&#44;1 &#177;9&#44;5 a&#241;os&#46; La puntuaci&#243;n del test de Fagerstr&#246;m fue de 6&#44;3 &#177;2&#44;1 puntos&#46; El 70&#44;8&#37;recibi&#243; tratamiento sustitutivo con nicotina y el 29&#44;2&#37;con bupropi&#243;n&#46; La probabilidad de mantenerse abstinente a los 6 meses fue del 62&#44;2&#37;&#46;Los individuos con alta dependencia presentaron menos probabilidad de permanecer abstinentes a los 6 meses&#44; as&#237; como aqu&#233;llos con mal cumplimiento terap&#233;utico&#46; No se encontraron diferencias en la probabilidad de abstinencia seg&#250;n el sexo y el tratamiento farmacol&#243;gico utilizado&#46;</p> <span class="elsevierStyleSectionTitle">CONCLUSIONES</span><p class="elsevierStyleSimplePara elsevierViewall">Los individuos con dependencia alta a la nicotina pueden beneficiarse del tratamiento intensivo en una unidad especializada de tabaquismo para conseguir la abstinencia mantenida&#46;</p>"
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Vol. 43. Issue 12.
Pages 669-673 (January 2007)
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Vol. 43. Issue 12.
Pages 669-673 (January 2007)
ORIGINAL ARTICLES
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Results of Smoking Cessation Therapy in a Specialist Unit
Visits
3574
Isabel Nerína,
Corresponding author
isabelne@unizar.es

Correspondence: Dra. I. Nerín. Departamento de Medicina y Psiquiatría. Facultad de Medicina, edificio B. Domingo Miral, s/n.50009 Zaragoza. España
, Pilar Novellaa, Asunción Belmonteb, Pilar Gargallob, Adriana Jiménez-Muroa, Adriana Marquetaa
a Unidad de Tabaquismo FMZ, Departamento de Medicina y Psiquiatría, Facultad de Medicina, Universidad de Zaragoza, Zaragoza, Spain
b Departamento de Métodos Estadísticos, Escuela Universitaria de Estudios Empresariales, Universidad de Zaragoza, Zaragoza, Spain
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OBJECTIVE

The aim of this study was to assess the results of smoking cessation therapy in a specialist unit by calculating the probability of continued abstinence at 6-month follow-up and analyzing differences according to the characteristics of the individuals.

PATIENTS AND METHODS

A prospective longitudinal study was undertaken in smokers who received multicomponent smoking-cessation therapy over a period of 3 months. Continued abstinence was assessed on the basis of self-report by participants and confirmed by measurement of exhaled carbon monoxide levels. Kaplan-Meier survival analysis was performed to assess the probability of continued abstinence. Log-rank tests were used to analyze differences in continued abstinence according to different qualitative variables.

RESULTS

The 1120 patients who participated in the study (56%men and 44%women) had a mean (SD) age of 44.1 (9.5) years. The mean score on the Fagerström test was 6.3 (2.1).Nicotine replacement therapy was provided in 70.8%of patients while 29.2%received bupropion. The probability of continued abstinence at 6 months was 62.2%. Individuals with a high dependence had a lower probability of continued abstinence at 6 months, as did those in whom treatment adherence was poor. No differences were observed in the probability of abstinence according to sex or type of pharmacological treatment.

CONCLUSIONS

Individuals with a high nicotine dependence can benefit from intensive smoking-cessation treatment in a specialist unit to achieve continued abstinence.

Key words:
Smoking
Smoking cessation
Smoking cessationunits
Survival analysis
Continued abstinence
OBJETIVO

Valorar los resultados del tratamiento del tabaquismo en una unidad especializada, mediante el cálculo de la probabilidad de permanecer abstinente a los 6 meses del seguimiento, y analizar las diferencias existentes según las características de los individuos.

PACIENTES Y MÉTODOS

Se ha realizado un estudio analítico prospectivo y longitudinal entre los fumadores que recibieron tratamiento multicomponente durante 3 meses. Se consideró la abstinencia continuada mediante la declaración de los propios participantes, confirmada con cooximetría. Se realizó un análisis de supervivencia por el método de Kaplan-Meier. Se aplicaron contrastes de rangos logarítmicos para estudiar las diferencias en la abstinencia continuada de los pacientes para las distintas categorías de las variables cualitativas.

RESULTADOS

Se estudió a 1.120 pacientes (un 56%varones y el 44%mujeres), con una edad media (±desviación estándar de 44,1 ±9,5 años. La puntuación del test de Fagerström fue de 6,3 ±2,1 puntos. El 70,8%recibió tratamiento sustitutivo con nicotina y el 29,2%con bupropión. La probabilidad de mantenerse abstinente a los 6 meses fue del 62,2%.Los individuos con alta dependencia presentaron menos probabilidad de permanecer abstinentes a los 6 meses, así como aquéllos con mal cumplimiento terapéutico. No se encontraron diferencias en la probabilidad de abstinencia según el sexo y el tratamiento farmacológico utilizado.

CONCLUSIONES

Los individuos con dependencia alta a la nicotina pueden beneficiarse del tratamiento intensivo en una unidad especializada de tabaquismo para conseguir la abstinencia mantenida.

Palabras clave:
Tabaquismo
Deshabituación
Unidades especializadas de tabaquismo
Análisis de supervivencia
Abstinencia contiuada
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Copyright © 2007. Sociedad Española de Neumología y Cirugía Torácica (SEPAR)
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