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Minshall" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "J Allergy Clin Immunol" "fecha" => "2000" "volumen" => "105" "paginaInicial" => "20" "paginaFinal" => "36" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10629448" "web" => "Medline" ] ] ] ] ] ] ] ] 2 => array:3 [ "identificador" => "bib0015" "etiqueta" => "3." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Animal models of asthma" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "K.F. Chung" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Eur Respir Rev" "fecha" => "1995" "volumen" => "5" "paginaInicial" => "184" "paginaFinal" => "187" ] ] ] ] ] ] 3 => array:3 [ "identificador" => "bib0020" "etiqueta" => "4." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Effects of inhaled glaucine on pulmonary responses to antigen in sensitized guinea-pigs" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "R. Pons" 1 => "P. Santamaría" 2 => "J. Suchankova" 3 => "J. Cortijo" 4 => "E. Morcillo" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Eur J Pharmacol" "fecha" => "2000" "volumen" => "397" "paginaInicial" => "187" "paginaFinal" => "195" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10844113" "web" => "Medline" ] ] ] ] ] ] ] ] 4 => array:3 [ "identificador" => "bib0025" "etiqueta" => "5." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Measurement of airflow obstruction in animals" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "N.B. Pride" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Eur Respir Rev" "fecha" => "1995" "volumen" => "5" "paginaInicial" => "188" "paginaFinal" => "194" ] ] ] ] ] ] 5 => array:3 [ "identificador" => "bib0030" "etiqueta" => "6." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "State of art: late asthmatic responses" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "P.M. O'Byrne" 1 => "J. Dolovich" 2 => "F.E. Hargreave" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1164/ajrccm/136.3.740" "Revista" => array:6 [ "tituloSerie" => "Am Rev Respir Dis" "fecha" => "1987" "volumen" => "136" "paginaInicial" => "740" "paginaFinal" => "751" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/3115156" "web" => "Medline" ] ] ] ] ] ] ] ] 6 => array:3 [ "identificador" => "bib0035" "etiqueta" => "7." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Animal models of late responses" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "W.M. Abraham" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Eur Respir Rev" "fecha" => "1995" "volumen" => "5" "paginaInicial" => "211" "paginaFinal" => "217" ] ] ] ] ] ] 7 => array:3 [ "identificador" => "bib0040" "etiqueta" => "8." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "A small-molecule, tight-binding inhibitor of the integrin alfa(4) beta(1) blocks antige-induced airway responses and inflammation in experimental asthma in sheep" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "W.M. Abraham" 1 => "A. Gill" 2 => "A. Ahmed" 3 => "N.M. Sielczak" 4 => "I.T. Lauredo" 5 => "Y. Botinnikova" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1164/ajrccm.162.2.9911061" "Revista" => array:6 [ "tituloSerie" => "Am J Respir Crit Care Med" "fecha" => "2000" "volumen" => "162" "paginaInicial" => "603" "paginaFinal" => "611" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10934094" "web" => "Medline" ] ] ] ] ] ] ] ] 8 => array:3 [ "identificador" => "bib0045" "etiqueta" => "9." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Effects of taurine on pulmonary responses to antigen in sensitized Brown-norway rats" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "J. Cortijo" 1 => "S. Blesa" 2 => "M. Martínez-Losa" 3 => "M. Mata" 4 => "E. Seda" 5 => "F. Santangelo" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Eur J Pharmacol" "fecha" => "2001" "volumen" => "431" "paginaInicial" => "111" "paginaFinal" => "117" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11716849" "web" => "Medline" ] ] ] ] ] ] ] ] 9 => array:3 [ "identificador" => "bib0050" "etiqueta" => "10." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Bronchodilator and antiinflamtory activities of SCA40: studies in human isolated bronchus, human eosinophils, and in the guinea-pig in vivo" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "J. Cortijo" 1 => "R. Pons" 2 => "P. Dasí" 3 => "N. Marín" 4 => "M. Martínez-Losa" 5 => "C. Advenier" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Naunyn-Schmiedeberg's Archives Pharmacol" "fecha" => "1997" "volumen" => "356" "paginaInicial" => "806" "paginaFinal" => "814" ] ] ] ] ] ] 10 => array:3 [ "identificador" => "bib0055" "etiqueta" => "11." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "acute airway hyperreactivity in the guinea-pig" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "J. Morley" 1 => "I.D. Chapman" 2 => "K. Hoshiko" 3 => "L. Mazzoni" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Eur Respir Rev" "fecha" => "1995" "volumen" => "5" "paginaInicial" => "202" "paginaFinal" => "210" ] ] ] ] ] ] 11 => array:3 [ "identificador" => "bib0060" "etiqueta" => "12." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Chronic models of airway hyperresponsiveness" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "C.D. Wegner" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Eur Respir Rev" "fecha" => "1995" "volumen" => "5" "paginaInicial" => "218" "paginaFinal" => "223" ] ] ] ] ] ] 12 => array:3 [ "identificador" => "bib0065" "etiqueta" => "13." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Animal models of asthma and chronic bronchitis" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "J.M. Drazen" 1 => "T. Takebayashi" 2 => "N.C. Long" 3 => "G.T. DeSanctis" 4 => "S.A. Shore" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Clin Exp Allergy" "fecha" => "1999" "volumen" => "29" "paginaInicial" => "37" "paginaFinal" => "47" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10444210" "web" => "Medline" ] ] ] ] ] ] ] ] 13 => array:3 [ "identificador" => "bib0070" "etiqueta" => "14." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Noninvasive measurement of airway responsiveness in allergic mice using barometric plethysmography" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "E. Hamelmann" 1 => "J. Schrarze" 2 => "K. Takeda" 3 => "A. Osihiba" 4 => "G.L. Larse" 5 => "C.G. Irvin" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1164/ajrccm.156.3.9606031" "Revista" => array:6 [ "tituloSerie" => "Am J Respir Crit Care Med" "fecha" => "1997" "volumen" => "156" "paginaInicial" => "766" "paginaFinal" => "775" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9309991" "web" => "Medline" ] ] ] ] ] ] ] ] 14 => array:3 [ "identificador" => "bib0075" "etiqueta" => "15." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Utility of murine systems to study asthma pathogenesis" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "G.L. Y-p Tu" 1 => "C.G. Larsen" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Eur Respir Rev" "fecha" => "1995" "volumen" => "5" "paginaInicial" => "224" "paginaFinal" => "230" ] ] ] ] ] ] 15 => array:3 [ "identificador" => "bib0080" "etiqueta" => "16." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Murine model of chronic human asthma" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "R.K. Kumar" 1 => "P.S. Foster" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1046/j.1440-1711.2001.00981.x" "Revista" => array:6 [ "tituloSerie" => "Immunol Cell Biol" "fecha" => "2001" "volumen" => "79" "paginaInicial" => "141" "paginaFinal" => "144" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11264707" "web" => "Medline" ] ] ] ] ] ] ] ] 16 => array:3 [ "identificador" => "bib0085" "etiqueta" => "17." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Understanding the phathogenesis of allergic asthma using mouse models" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "K.P. Leong" 1 => "D.P. Huston" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/S1081-1206(10)62201-6" "Revista" => array:6 [ "tituloSerie" => "Ann Allergy Asthma Immunol" "fecha" => "2001" "volumen" => "87" "paginaInicial" => "96" "paginaFinal" => "109" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11527255" "web" => "Medline" ] ] ] ] ] ] ] ] 17 => array:3 [ "identificador" => "bib0090" "etiqueta" => "18." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Murine models of asthma in understanding immune dysregulation in human asthma" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "M. Wills-Karp" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Immunopharmacology" "fecha" => "2000" "volumen" => "48" "paginaInicial" => "263" "paginaFinal" => "268" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10960667" "web" => "Medline" ] ] ] ] ] ] ] ] 18 => array:3 [ "identificador" => "bib0095" "etiqueta" => "19." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "New insihgts into the role of cytokines in astma" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "J.C. Renauld" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "J Clin Pathol" "fecha" => "2001" "volumen" => "54" "paginaInicial" => "577" "paginaFinal" => "589" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11477111" "web" => "Medline" ] ] ] ] ] ] ] ] 19 => array:3 [ "identificador" => "bib0100" "etiqueta" => "20." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Passive sensitization of human airways increases responsiveness to LTC4" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "D. Schmidt" 1 => "E. Ruehlmann" 2 => "D. Branscheid" 3 => "H. Magnusesen" 4 => "K.F. Raben" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Eur Respi J" "fecha" => "1999" "volumen" => "14" "paginaInicial" => "315" "paginaFinal" => "319" ] ] ] ] ] ] 20 => array:3 [ "identificador" => "bib0105" "etiqueta" => "21." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Effects of selective phosphodiesterase inhibitors on allergen-induced contraction and hyperreactivity in passvely sensitized human airways in vitro" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "J. Cortijo" 1 => "E.J. Morcillo" 2 => "B. Sarria" 3 => "P. Santamaría" 4 => "P. Ferlanga" 5 => "F. Marchini" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:4 [ "tituloSerie" => "Am J Respi Crit Care Med" "fecha" => "2001" "volumen" => "163" "paginaInicial" => "A432" ] ] ] ] ] ] ] ] ] ] ] "idiomaDefecto" => "es" "url" => "/03002896/0000003900000002/v1_201307081521/S0300289603753228/v1_201307081521/es/main.assets" "Apartado" => array:4 [ "identificador" => "14517" "tipo" => "SECCION" "es" => array:2 [ "titulo" => "Editorials / Editoriales" "idiomaDefecto" => true ] "idiomaDefecto" => "es" ] "PDF" => "https://static.elsevier.es/multimedia/03002896/0000003900000002/v1_201307081521/S0300289603753228/v1_201307081521/es/main.pdf?idApp=UINPBA00003Z&text.app=https://archbronconeumol.org/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0300289603753228?idApp=UINPBA00003Z" ]
Journal Information
Vol. 39. Issue 2.
Pages 54-56 (February 2003)
Vol. 39. Issue 2.
Pages 54-56 (February 2003)
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Modelos experimentales de asma. Aportaciones y limitaciones
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J. Cortijo Gimeno
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Julio.Cortijo@uv.es
Correspondencia: Departamento de Farmacología. Facultadde Medicina y Odontología. Avda. Blasco Ibáñez, 15. 46010 Valencia. España
Correspondencia: Departamento de Farmacología. Facultadde Medicina y Odontología. Avda. Blasco Ibáñez, 15. 46010 Valencia. España
Departamento de Farmacología. Facultad de Medicina y Odontología. Valencia. España
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Bibliografía
[1.]
W.W. Busse, R.F. Lemanske.
Asthma.
N Engl J Med, 344 (2001), pp. 350-362
[2.]
Q.A. Hamid, E.M. Minshall.
Molecular pathology of allergic disease. I. Lower airway disease.
J Allergy Clin Immunol, 105 (2000), pp. 20-36
[3.]
K.F. Chung.
Animal models of asthma.
Eur Respir Rev, 5 (1995), pp. 184-187
[4.]
R. Pons, P. Santamaría, J. Suchankova, J. Cortijo, E. Morcillo.
Effects of inhaled glaucine on pulmonary responses to antigen in sensitized guinea-pigs.
Eur J Pharmacol, 397 (2000), pp. 187-195
[5.]
N.B. Pride.
Measurement of airflow obstruction in animals.
Eur Respir Rev, 5 (1995), pp. 188-194
[6.]
P.M. O'Byrne, J. Dolovich, F.E. Hargreave.
State of art: late asthmatic responses.
Am Rev Respir Dis, 136 (1987), pp. 740-751
[7.]
W.M. Abraham.
Animal models of late responses.
Eur Respir Rev, 5 (1995), pp. 211-217
[8.]
W.M. Abraham, A. Gill, A. Ahmed, N.M. Sielczak, I.T. Lauredo, Y. Botinnikova, et al.
A small-molecule, tight-binding inhibitor of the integrin alfa(4) beta(1) blocks antige-induced airway responses and inflammation in experimental asthma in sheep.
Am J Respir Crit Care Med, 162 (2000), pp. 603-611
[9.]
J. Cortijo, S. Blesa, M. Martínez-Losa, M. Mata, E. Seda, F. Santangelo, et al.
Effects of taurine on pulmonary responses to antigen in sensitized Brown-norway rats.
Eur J Pharmacol, 431 (2001), pp. 111-117
[10.]
J. Cortijo, R. Pons, P. Dasí, N. Marín, M. Martínez-Losa, C. Advenier, et al.
Bronchodilator and antiinflamtory activities of SCA40: studies in human isolated bronchus, human eosinophils, and in the guinea-pig in vivo.
Naunyn-Schmiedeberg's Archives Pharmacol, 356 (1997), pp. 806-814
[11.]
J. Morley, I.D. Chapman, K. Hoshiko, L. Mazzoni.
acute airway hyperreactivity in the guinea-pig.
Eur Respir Rev, 5 (1995), pp. 202-210
[12.]
C.D. Wegner.
Chronic models of airway hyperresponsiveness.
Eur Respir Rev, 5 (1995), pp. 218-223
[13.]
J.M. Drazen, T. Takebayashi, N.C. Long, G.T. DeSanctis, S.A. Shore.
Animal models of asthma and chronic bronchitis.
Clin Exp Allergy, 29 (1999), pp. 37-47
[14.]
E. Hamelmann, J. Schrarze, K. Takeda, A. Osihiba, G.L. Larse, C.G. Irvin.
Noninvasive measurement of airway responsiveness in allergic mice using barometric plethysmography.
Am J Respir Crit Care Med, 156 (1997), pp. 766-775
[15.]
G.L. Y-p Tu, C.G. Larsen.
Utility of murine systems to study asthma pathogenesis.
Eur Respir Rev, 5 (1995), pp. 224-230
[16.]
R.K. Kumar, P.S. Foster.
Murine model of chronic human asthma.
Immunol Cell Biol, 79 (2001), pp. 141-144
[17.]
K.P. Leong, D.P. Huston.
Understanding the phathogenesis of allergic asthma using mouse models.
Ann Allergy Asthma Immunol, 87 (2001), pp. 96-109
[18.]
M. Wills-Karp.
Murine models of asthma in understanding immune dysregulation in human asthma.
Immunopharmacology, 48 (2000), pp. 263-268
[19.]
J.C. Renauld.
New insihgts into the role of cytokines in astma.
J Clin Pathol, 54 (2001), pp. 577-589
[20.]
D. Schmidt, E. Ruehlmann, D. Branscheid, H. Magnusesen, K.F. Raben.
Passive sensitization of human airways increases responsiveness to LTC4.
Eur Respi J, 14 (1999), pp. 315-319
[21.]
J. Cortijo, E.J. Morcillo, B. Sarria, P. Santamaría, P. Ferlanga, F. Marchini.
Effects of selective phosphodiesterase inhibitors on allergen-induced contraction and hyperreactivity in passvely sensitized human airways in vitro.
Am J Respi Crit Care Med, 163 (2001), pp. A432
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