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        "resumen" => "<span class="elsevierStyleSectionTitle">Objective</span><p class="elsevierStyleSimplePara elsevierViewall">TO investigate the changes in lung cancer incidence&#44; histological type&#44; and survival in patients in the north of the province of Castell&#243;n&#44; Spain&#44; during a follow-up period of 10 years&#44; and to compare the findings with other national and international studies&#46;</p> <span class="elsevierStyleSectionTitle">Patients and Method</span><p class="elsevierStyleSimplePara elsevierViewall">All patients diagnosed with lung cancer between January 1&#44; 1993 and December 31&#44; 2002 were included in this prospective&#44; observational study&#46; Disease was confirmed by biopsy or suspected from clinical&#44; radiological&#44; and&#47;or bronchoscopic findings&#46;</p> <span class="elsevierStyleSectionTitle">Results</span><p class="elsevierStyleSimplePara elsevierViewall">In the study period&#44; 271 patients were diagnosed with lung cancer &#40;239 men and 32 women&#41;&#44; with a mean &#40;SD&#41; age of 66&#46;8 &#40;11&#46;8&#41; years&#46; The age-adjusted incidence rate standardized to the world population was 20&#46;42 cases per 100&#8200;000 population&#46; Smokers or ex-smokers comprised 88&#46;1&#37; of the study population&#44; and 72&#46;6&#37; of patients were over 60 years old&#46; Biopsy confirmation was obtained in 262 cases &#40;96&#46;7&#37;&#41;&#46; Squamous cell carcinoma predominated &#40;46&#46;5&#37;&#41; but the proportion of adenocarcinoma increased &#40;23&#46;6&#37;&#41;&#46; Surgery was possible in only 22&#37; of the patients&#46; Mean overall 5-year survival was 15&#46;7 months&#46;</p> <span class="elsevierStyleSectionTitle">Conclusions</span><p class="elsevierStyleSimplePara elsevierViewall">In the north of the province of Castell&#243;n&#44; the incidence of lung cancer continues to increase in men but has decreased slightly in women&#46; Squamous cell carcinoma is the most common type&#44; but the incidence of adenocarcinoma has clearly increased&#46; Overall&#44; survival did not improve during the 10 years of follow up despite advances in treatment&#46;</p>"
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        "resumen" => "<span class="elsevierStyleSectionTitle">Objetivo</span><p class="elsevierStyleSimplePara elsevierViewall">Conocer la evoluci&#243;n de la incidencia&#44; tipos histol&#243;gicos y supervivencia del carcinoma broncog&#233;nico en el norte de la provincia de Castell&#243;n&#44; en un per&#237;odo de segui-miento de 10 a&#241;os&#44; y comparar los resultados con los de otros estudios nacionales e internacionales&#46;</p> <span class="elsevierStyleSectionTitle">Pacientes Y M&#233;todo</span><p class="elsevierStyleSimplePara elsevierViewall">Se ha realizado un estudio prospec-tivo y observacional&#44; en el que se incluy&#243; a todos los pacientes diagnosticados de carcinoma broncog&#233;nico desde el 1 de enero de 1993 hasta el 31 de diciembre de 2002&#46; Se exigi&#243; la confirmaci&#243;n citohistol&#243;gica o la sospecha basada en datos cl&#237;nicos&#44; radiol&#243;gicos y&#47;o broncosc&#243;picos&#46;</p> <span class="elsevierStyleSectionTitle">Resultados</span><p class="elsevierStyleSimplePara elsevierViewall">En el per&#237;odo estudiado se diagnostic&#243; de carcinoma broncog&#233;nico a 271 pacientes &#40;239 varones y 32 muje-res&#41;&#44; con una edad media &#40;&#177; desviaci&#243;n est&#225;ndar&#41; de 66&#44;8 &#177; 11&#44;8 a&#241;os&#46; La tasa de incidencia ajustada a la poblaci&#243;n mun-dial fue de 20&#44;42 casos por 100&#46;000 habitantes&#46; El 88&#44;1&#37; eran fumadores o ex fumadores&#44; y el 72&#44;6&#37; de los pacientes ten&#237;a m&#225;s de 60 a&#241;os&#46; Se obtuvo confirmaci&#243;n citohistol&#243;gica en 262 &#40;96&#44;7&#37;&#41; casos&#46; Predomin&#243; el tipo epidermoide &#40;46&#44;5&#37;&#41; pero con un ascenso del adenocarcinoma &#40;23&#44;6&#37;&#41;&#44; y s&#243;lo se pudo realizar tratamiento con cirug&#237;a en el 22&#37; de los casos&#46; La supervivencia media global a los 5 a&#241;os ha sido de 15&#44;7 meses&#46;</p> <span class="elsevierStyleSectionTitle">Conclusiones</span><p class="elsevierStyleSimplePara elsevierViewall">En el norte de la provincia de Castell&#243;n la incidencia de carcinoma broncog&#233;nico sigue aumentando en los varones y ha disminuido ligeramente en las mujeres&#46; Predomina el carcinoma epidermoide pero con un ascenso claro del adenocarcinoma&#46; A pesar de los avances del tratamiento&#44; desde una visi&#243;n global&#44; la supervivencia no ha me-j or ado en los 10 a&#241;os de seguimiento&#46;</p>"
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Vol. 40. Issue 12.
Pages 553-557 (December 2004)
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Vol. 40. Issue 12.
Pages 553-557 (December 2004)
Original Articles
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Evolution of Lung Cancer in the North of the Province of Castellón, Spain, 1993-2002
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L. Miraveta,
Corresponding author
miravet_lui@gva.es

Correspondence: Dr. L. Miravet. Unidad de Neumología. Servicio de Medicina Interna. Hospital Comarcal de Vinaroz. Avda. Gil de Atrocillo, s/n. 12500 Vinaroz. Castellón. España
, A. Paradísb, S. Peláezb, M. Arnalc, F. Cabadésc
a Unidad de Neumología, Servicio de Medicina Interna, Hospital Comarcal de Vinaroz, Vinaroz, Castellón, Spain
b Servicio de Anatomía Patológica, Hospital Comarcal de Vinaroz, Vinaroz, Castellón, Spain
c Servicio de Medicina Interna, Hospital Comarcal de Vinaroz, Vinaroz, Castellón, Spain
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Objective

TO investigate the changes in lung cancer incidence, histological type, and survival in patients in the north of the province of Castellón, Spain, during a follow-up period of 10 years, and to compare the findings with other national and international studies.

Patients and Method

All patients diagnosed with lung cancer between January 1, 1993 and December 31, 2002 were included in this prospective, observational study. Disease was confirmed by biopsy or suspected from clinical, radiological, and/or bronchoscopic findings.

Results

In the study period, 271 patients were diagnosed with lung cancer (239 men and 32 women), with a mean (SD) age of 66.8 (11.8) years. The age-adjusted incidence rate standardized to the world population was 20.42 cases per 100 000 population. Smokers or ex-smokers comprised 88.1% of the study population, and 72.6% of patients were over 60 years old. Biopsy confirmation was obtained in 262 cases (96.7%). Squamous cell carcinoma predominated (46.5%) but the proportion of adenocarcinoma increased (23.6%). Surgery was possible in only 22% of the patients. Mean overall 5-year survival was 15.7 months.

Conclusions

In the north of the province of Castellón, the incidence of lung cancer continues to increase in men but has decreased slightly in women. Squamous cell carcinoma is the most common type, but the incidence of adenocarcinoma has clearly increased. Overall, survival did not improve during the 10 years of follow up despite advances in treatment.

Key Words:
Lung cancer
Incidence
Treatment
Survival
Objetivo

Conocer la evolución de la incidencia, tipos histológicos y supervivencia del carcinoma broncogénico en el norte de la provincia de Castellón, en un período de segui-miento de 10 años, y comparar los resultados con los de otros estudios nacionales e internacionales.

Pacientes Y Método

Se ha realizado un estudio prospec-tivo y observacional, en el que se incluyó a todos los pacientes diagnosticados de carcinoma broncogénico desde el 1 de enero de 1993 hasta el 31 de diciembre de 2002. Se exigió la confirmación citohistológica o la sospecha basada en datos clínicos, radiológicos y/o broncoscópicos.

Resultados

En el período estudiado se diagnosticó de carcinoma broncogénico a 271 pacientes (239 varones y 32 muje-res), con una edad media (± desviación estándar) de 66,8 ± 11,8 años. La tasa de incidencia ajustada a la población mun-dial fue de 20,42 casos por 100.000 habitantes. El 88,1% eran fumadores o ex fumadores, y el 72,6% de los pacientes tenía más de 60 años. Se obtuvo confirmación citohistológica en 262 (96,7%) casos. Predominó el tipo epidermoide (46,5%) pero con un ascenso del adenocarcinoma (23,6%), y sólo se pudo realizar tratamiento con cirugía en el 22% de los casos. La supervivencia media global a los 5 años ha sido de 15,7 meses.

Conclusiones

En el norte de la provincia de Castellón la incidencia de carcinoma broncogénico sigue aumentando en los varones y ha disminuido ligeramente en las mujeres. Predomina el carcinoma epidermoide pero con un ascenso claro del adenocarcinoma. A pesar de los avances del tratamiento, desde una visión global, la supervivencia no ha me-j or ado en los 10 años de seguimiento.

Palabras clave:
Carcinoma broncogénico
Incidencia
Tratamiento
Supervivencia
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