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Evolution of Lung Cancer in the North of the Province of Castellón, Spain, 1993-2002
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Martínez-Moragón, L. García Ferrer, B. Serra Sanchos, E. Fernández Fabrellas, A. Gómez Belda, R. Julve Pardo" "autores" => array:6 [ 0 => array:2 [ "nombre" => "E." "apellidos" => "Martínez-Moragón" ] 1 => array:3 [ "preGrado" => "Dra" "nombre" => "L." "apellidos" => "García Ferrer" ] 2 => array:2 [ "nombre" => "B." "apellidos" => "Serra Sanchos" ] 3 => array:2 [ "nombre" => "E." "apellidos" => "Fernández Fabrellas" ] 4 => array:2 [ "nombre" => "A." "apellidos" => "Gómez Belda" ] 5 => array:2 [ "nombre" => "R." "apellidos" => "Julve Pardo" ] ] ] ] ] "idiomaDefecto" => "en" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S157921290660373X?idApp=UINPBA00003Z" "url" => "/15792129/0000004000000012/v1_201305141825/S157921290660373X/v1_201305141825/en/main.assets" ] "en" => array:14 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Original Articles</span>" "titulo" => "Evolution of Lung Cancer in the North of the Province of Castellón, Spain, 1993-2002" "tieneTextoCompleto" => 0 "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "553" "paginaFinal" => "557" ] ] "autores" => array:1 [ 0 => array:4 [ "autoresLista" => "L. Miravet, A. Paradís, S. Peláez, M. Arnal, F. Cabadés" "autores" => array:5 [ 0 => array:5 [ "preGrado" => "Dr." "nombre" => "L." "apellidos" => "Miravet" "email" => array:1 [ 0 => "miravet_lui@gva.es" ] "referencia" => array:2 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff1" ] 1 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">*</span>" "identificador" => "cor1" ] ] ] 1 => array:3 [ "nombre" => "A." "apellidos" => "Paradís" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff2" ] ] ] 2 => array:3 [ "nombre" => "S." "apellidos" => "Peláez" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff2" ] ] ] 3 => array:3 [ "nombre" => "M." "apellidos" => "Arnal" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">c</span>" "identificador" => "aff3" ] ] ] 4 => array:3 [ "nombre" => "F." "apellidos" => "Cabadés" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">c</span>" "identificador" => "aff3" ] ] ] ] "afiliaciones" => array:3 [ 0 => array:3 [ "entidad" => "Unidad de Neumología, Servicio de Medicina Interna, Hospital Comarcal de Vinaroz, Vinaroz, Castellón, Spain" "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff1" ] 1 => array:3 [ "entidad" => "Servicio de Anatomía Patológica, Hospital Comarcal de Vinaroz, Vinaroz, Castellón, Spain" "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff2" ] 2 => array:3 [ "entidad" => "Servicio de Medicina Interna, Hospital Comarcal de Vinaroz, Vinaroz, Castellón, Spain" "etiqueta" => "<span class="elsevierStyleSup">c</span>" "identificador" => "aff3" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor1" "etiqueta" => "*" "correspondencia" => "Correspondence: Dr. L. Miravet. Unidad de Neumología. Servicio de Medicina Interna. Hospital Comarcal de Vinaroz. Avda. Gil de Atrocillo, s/n. 12500 Vinaroz. Castellón. España" ] ] ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "2004-01-12" "fechaAceptado" => "2004-03-09" "PalabrasClave" => array:2 [ "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Key Words" "identificador" => "xpalclavsec153217" "palabras" => array:4 [ 0 => "Lung cancer" 1 => "Incidence" 2 => "Treatment" 3 => "Survival" ] ] ] "es" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palabras clave" "identificador" => "xpalclavsec153218" "palabras" => array:4 [ 0 => "Carcinoma broncogénico" 1 => "Incidencia" 2 => "Tratamiento" 3 => "Supervivencia" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "en" => array:1 [ "resumen" => "<span class="elsevierStyleSectionTitle">Objective</span><p class="elsevierStyleSimplePara elsevierViewall">TO investigate the changes in lung cancer incidence, histological type, and survival in patients in the north of the province of Castellón, Spain, during a follow-up period of 10 years, and to compare the findings with other national and international studies.</p> <span class="elsevierStyleSectionTitle">Patients and Method</span><p class="elsevierStyleSimplePara elsevierViewall">All patients diagnosed with lung cancer between January 1, 1993 and December 31, 2002 were included in this prospective, observational study. Disease was confirmed by biopsy or suspected from clinical, radiological, and/or bronchoscopic findings.</p> <span class="elsevierStyleSectionTitle">Results</span><p class="elsevierStyleSimplePara elsevierViewall">In the study period, 271 patients were diagnosed with lung cancer (239 men and 32 women), with a mean (SD) age of 66.8 (11.8) years. The age-adjusted incidence rate standardized to the world population was 20.42 cases per 100 000 population. Smokers or ex-smokers comprised 88.1% of the study population, and 72.6% of patients were over 60 years old. Biopsy confirmation was obtained in 262 cases (96.7%). Squamous cell carcinoma predominated (46.5%) but the proportion of adenocarcinoma increased (23.6%). Surgery was possible in only 22% of the patients. Mean overall 5-year survival was 15.7 months.</p> <span class="elsevierStyleSectionTitle">Conclusions</span><p class="elsevierStyleSimplePara elsevierViewall">In the north of the province of Castellón, the incidence of lung cancer continues to increase in men but has decreased slightly in women. Squamous cell carcinoma is the most common type, but the incidence of adenocarcinoma has clearly increased. Overall, survival did not improve during the 10 years of follow up despite advances in treatment.</p>" ] "es" => array:1 [ "resumen" => "<span class="elsevierStyleSectionTitle">Objetivo</span><p class="elsevierStyleSimplePara elsevierViewall">Conocer la evolución de la incidencia, tipos histológicos y supervivencia del carcinoma broncogénico en el norte de la provincia de Castellón, en un período de segui-miento de 10 años, y comparar los resultados con los de otros estudios nacionales e internacionales.</p> <span class="elsevierStyleSectionTitle">Pacientes Y Método</span><p class="elsevierStyleSimplePara elsevierViewall">Se ha realizado un estudio prospec-tivo y observacional, en el que se incluyó a todos los pacientes diagnosticados de carcinoma broncogénico desde el 1 de enero de 1993 hasta el 31 de diciembre de 2002. Se exigió la confirmación citohistológica o la sospecha basada en datos clínicos, radiológicos y/o broncoscópicos.</p> <span class="elsevierStyleSectionTitle">Resultados</span><p class="elsevierStyleSimplePara elsevierViewall">En el período estudiado se diagnosticó de carcinoma broncogénico a 271 pacientes (239 varones y 32 muje-res), con una edad media (± desviación estándar) de 66,8 ± 11,8 años. La tasa de incidencia ajustada a la población mun-dial fue de 20,42 casos por 100.000 habitantes. El 88,1% eran fumadores o ex fumadores, y el 72,6% de los pacientes tenía más de 60 años. Se obtuvo confirmación citohistológica en 262 (96,7%) casos. Predominó el tipo epidermoide (46,5%) pero con un ascenso del adenocarcinoma (23,6%), y sólo se pudo realizar tratamiento con cirugía en el 22% de los casos. La supervivencia media global a los 5 años ha sido de 15,7 meses.</p> <span class="elsevierStyleSectionTitle">Conclusiones</span><p class="elsevierStyleSimplePara elsevierViewall">En el norte de la provincia de Castellón la incidencia de carcinoma broncogénico sigue aumentando en los varones y ha disminuido ligeramente en las mujeres. Predomina el carcinoma epidermoide pero con un ascenso claro del adenocarcinoma. A pesar de los avances del tratamiento, desde una visión global, la supervivencia no ha me-j or ado en los 10 años de seguimiento.</p>" ] ] "bibliografia" => array:2 [ "titulo" => "REFERENCES" "seccion" => array:1 [ 0 => array:1 [ "bibliografiaReferencia" => array:23 [ 0 => array:3 [ "identificador" => "bib1" "etiqueta" => "1" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Cancer statistics" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "RT Greenlee" 1 => "MB Hill-Harmon" 2 => "T Murray" 3 => "M Thum" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "CA Cancer J Clin" "fecha" => "2001" "volumen" => "51" "paginaInicial" => "15" "paginaFinal" => "36" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11577478" "web" => "Medline" ] ] ] ] ] ] ] ] 1 => array:3 [ "identificador" => "bib2" "etiqueta" => "2" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Mortalidad por cáncer de pulmón: inicio del declive en los varones de Barcelona" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "JR Villalbí" 1 => "MI Pasarin" 2 => "M Nebot" 3 => "C Borrell" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Med Clin (Barc)" "fecha" => "2001" "volumen" => "117" "paginaInicial" => "727" "paginaFinal" => "731" ] ] ] ] ] ] 2 => array:3 [ "identificador" => "bib3" "etiqueta" => "3" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "El cáncer de pulmón en España. 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| Year/Month | Html | Total | |
|---|---|---|---|
| 2024 November | 2 | 3 | 5 |
| 2024 October | 30 | 16 | 46 |
| 2024 September | 32 | 21 | 53 |
| 2024 August | 41 | 45 | 86 |
| 2024 July | 29 | 22 | 51 |
| 2024 June | 30 | 21 | 51 |
| 2024 May | 35 | 28 | 63 |
| 2024 April | 20 | 20 | 40 |
| 2024 March | 21 | 16 | 37 |
| 2024 February | 16 | 21 | 37 |
| 2023 March | 3 | 2 | 5 |
| 2023 February | 15 | 22 | 37 |
| 2023 January | 14 | 24 | 38 |
| 2022 December | 18 | 33 | 51 |
| 2022 November | 20 | 26 | 46 |
| 2022 October | 17 | 27 | 44 |
| 2022 September | 13 | 29 | 42 |
| 2022 August | 23 | 28 | 51 |
| 2022 July | 18 | 40 | 58 |
| 2022 June | 16 | 36 | 52 |
| 2022 May | 31 | 32 | 63 |
| 2022 April | 20 | 25 | 45 |
| 2022 March | 19 | 29 | 48 |
| 2022 February | 24 | 29 | 53 |
| 2022 January | 15 | 36 | 51 |
| 2021 December | 17 | 38 | 55 |
| 2021 November | 13 | 33 | 46 |
| 2021 October | 19 | 39 | 58 |
| 2021 September | 19 | 39 | 58 |
| 2021 August | 8 | 29 | 37 |
| 2021 July | 13 | 33 | 46 |
| 2021 June | 9 | 32 | 41 |
| 2021 May | 14 | 19 | 33 |
| 2021 April | 21 | 46 | 67 |
| 2021 March | 17 | 11 | 28 |
| 2021 February | 10 | 13 | 23 |
| 2021 January | 7 | 14 | 21 |
| 2020 December | 6 | 11 | 17 |
| 2020 November | 10 | 9 | 19 |
| 2020 October | 10 | 11 | 21 |
| 2020 September | 3 | 3 | 6 |
| 2020 August | 6 | 10 | 16 |
| 2020 July | 10 | 13 | 23 |
| 2020 June | 9 | 5 | 14 |
| 2020 May | 25 | 10 | 35 |
| 2020 April | 13 | 9 | 22 |
| 2020 March | 11 | 14 | 25 |
| 2020 February | 9 | 9 | 18 |
| 2020 January | 15 | 13 | 28 |
| 2019 December | 23 | 14 | 37 |
| 2019 November | 18 | 11 | 29 |
| 2019 October | 9 | 6 | 15 |
| 2019 September | 10 | 6 | 16 |
| 2019 August | 16 | 8 | 24 |
| 2019 July | 9 | 14 | 23 |
| 2019 June | 10 | 4 | 14 |
| 2019 May | 15 | 15 | 30 |
| 2019 April | 12 | 14 | 26 |
| 2019 March | 21 | 13 | 34 |
| 2019 February | 12 | 13 | 25 |
| 2019 January | 12 | 10 | 22 |
| 2018 December | 6 | 11 | 17 |
| 2018 November | 30 | 10 | 40 |
| 2018 October | 19 | 13 | 32 |
| 2018 September | 9 | 8 | 17 |
| 2018 May | 6 | 0 | 6 |
| 2018 April | 3 | 7 | 10 |
| 2018 March | 5 | 5 | 10 |
| 2018 February | 7 | 11 | 18 |
| 2018 January | 4 | 16 | 20 |
| 2017 December | 6 | 7 | 13 |
| 2017 November | 6 | 8 | 14 |
| 2017 October | 4 | 9 | 13 |
| 2017 September | 3 | 4 | 7 |
| 2017 August | 6 | 6 | 12 |
| 2017 July | 1 | 3 | 4 |
| 2017 June | 8 | 22 | 30 |
| 2017 May | 8 | 8 | 16 |
| 2017 April | 4 | 3 | 7 |
| 2017 March | 1 | 5 | 6 |
| 2017 January | 3 | 5 | 8 |
| 2016 December | 11 | 5 | 16 |
| 2016 November | 14 | 7 | 21 |
| 2016 October | 15 | 4 | 19 |
| 2016 September | 15 | 6 | 21 |
| 2016 August | 10 | 6 | 16 |
| 2016 July | 6 | 0 | 6 |
| 2016 March | 3 | 0 | 3 |
| 2015 December | 2 | 0 | 2 |
| 2015 October | 28 | 1 | 29 |
| 2015 September | 30 | 9 | 39 |
| 2015 August | 25 | 8 | 33 |
| 2015 July | 21 | 7 | 28 |
| 2015 June | 19 | 7 | 26 |
| 2015 May | 32 | 4 | 36 |
| 2015 April | 20 | 6 | 26 |
| 2015 March | 23 | 6 | 29 |
| 2015 February | 15 | 1 | 16 |
| 2015 January | 16 | 4 | 20 |
| 2014 December | 13 | 4 | 17 |
| 2014 November | 13 | 5 | 18 |
| 2014 October | 29 | 9 | 38 |
| 2014 September | 28 | 6 | 34 |
| 2014 August | 20 | 6 | 26 |
| 2014 July | 16 | 5 | 21 |
| 2014 June | 27 | 8 | 35 |
| 2014 May | 38 | 8 | 46 |
| 2014 April | 33 | 5 | 38 |
| 2014 March | 52 | 8 | 60 |
| 2014 February | 47 | 11 | 58 |
| 2014 January | 25 | 8 | 33 |
| 2013 December | 28 | 12 | 40 |
| 2013 November | 19 | 7 | 26 |
| 2013 October | 23 | 8 | 31 |
| 2013 September | 23 | 10 | 33 |
| 2013 August | 26 | 5 | 31 |
| 2013 July | 41 | 15 | 56 |
| 2013 June | 30 | 7 | 37 |
| 2013 May | 25 | 4 | 29 |
| 2013 April | 24 | 4 | 28 |
| 2013 March | 6 | 1 | 7 |
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