Journal Information
Vol. 27. Issue 4.
Pages 162-165 (May 1991)
Share
Share
Download PDF
More article options
Vol. 27. Issue 4.
Pages 162-165 (May 1991)
Full text access
Cancer broncopulmonar, tipo bronquioloalveolar. Estudio de once casos y revision de la literatura
Bronchopulmonary cancer of bronchioalveolar type. Report of 11 cases and review of the literature
Visits
3794
I. García-Talavera, F. García Río, M. Vázquez, J.F. Francés, S. Díaz Lobato, J.M. Pino, C. Villasante
Servicios de Neumología. Hospital La Paz. Universidad Autónoma. Madrid
B. García Rubio*
* Anatomía Patológica. Hospital La Paz. Universidad Autónoma. Madrid
This item has received
Article information
Abstract
Bibliography
Download PDF
Statistics

Estudiamos 11 pacientes diagnosticados de carcinoma bronquioloalveolar en los últimos 12 años. Analizamos la presentación clínica y radiológica, las pruebas diagnósticas y el estadio clínico. La edad media de presentación fue de 58,5 años. Predominaron mujeres sobre hombres (2,6:1). En dos pacientes existían antecedentes de tabaquismo y sólo en un caso se comprobó fibrosis previa en el área de la neoplasia. El síntoma más frecuente fue la tos (54,5%) y no hubo evidencia de hemoptisis en ningún paciente. Casi un 30% fueron asintomáticos en el momento del diagnóstico. El patrón radiológico más destacado fue el alveolar (72,7%) y en segundo lugar el de nodulo o masa (27,3%), en contra de otras series. La prueba diagnóstica de rutina más sensible (45,5%) fue la citología del broncoaspirado (BAS), mientras que la de esputo aportó escasa información. Casi la mitad estaban en un estadio inicial (estadio I) en el momento del diagnóstico.

We studied 11 patients with bronchioalveolar carcinoma during the last 12 years. We analyze the clinical picture, the radiologic data, the diagnostic procedures, and the clinical stage. The mean age of presentation of the illnes was 58.5 years. There was a predominance of females (ratio 2.6:1). Two patients were smokers. In one case there was previous fibrosis on the neoplasic area. Cough was the most frequent symptom (54.5%). No patient had evidence of hemoptysis. Nearly 30% of the cases were asymptomatic when the diagnosis was made. The most revelant radiologic pattern was of alveolar type (72.7%) in contrast with the presence of a mass or a nodule (27.3%) which in other series was more commonly seen. The most sensitive routine diagnostic procedure (45.5%) was cytologic examination of the bronchio aspirate. Sputum examination offered scanty information. Nearly 50% of patients were in a initial stage (stage I) of tumor growing when the diagnosis was established.

Full text is only aviable in PDF
Bibliografía
[1.]
J.W. Bell, K.P. Knudtson.
Observations on the natural history of bronchioalveolar cell carcinoma: Experience with 21 cases.
Am Rev RespirDis, 83 (1961), pp. 660-667
[2.]
C.F. Storey, K.P. Knudtson, B.J. Lawrence.
Bronchiolar (“alveolar cell”) carcinoma of the lung.
J Thorac Surg, 26 (1953), pp. 331-406
[3.]
J.T. Manning, H.J. Spjut, J.A. Tschen.
Bronchoalveolar carcinoma: the significance of two histopathologic types.
Cancer, 54 (1984), pp. 525-534
[4.]
W.F. Grigioni, G. Biagini, S. Garbisa, et al.
Immunohistochemical study of basement membrane antigens in bronchioalveolar carcinoma.
Am J Pathol, 128 (1987), pp. 217-224
[5.]
J.S.T. Thomas, W.M. Tullett, B.H.R. Stack.
Bronchioalveolar cell carcinoma: A 21 year retrospective study of cases at the Western Infirmary, Glasgow.
Br J Dis Chest, 79 (1985), pp. 132-140
[6.]
L.G. Ludington, J.J. Verska, T. Howard, G. Kypridakis, L.A. Brewer.
Bronchiolar carcinoma (alveolar cell) another great imitator. A review of 41 cases.
Chest, 61 (1972), pp. 622-628
[7.]
S.D. Greenberg, M.N. Smith, H.J. Spjut.
Bronchio-alveolar carcinoma-cell of origin.
Am J Clin Pathol, 63 (1975), pp. 153-167
[8.]
C. Kuhn.
Fine structure of bronchioalveolar cell carcinoma.
Cáncer, 30 (1972), pp. 1.107-1.118
[9.]
J.C. Donaldson, D.B. Kaminsky, R.C. Elliot.
Bronchiolar carcinoma Report of 11 cases and review of the literature.
Cancer, 41 (1978), pp. 250-258
[10.]
A.A. Liebow.
Bronchiolo-alveolar carcinoma..
Adv Intern Med, 10 (1960), pp. 329-358
[11.]
D.E. Bennett, W.F. Sasser.
Bronchiolar carcinoma: A valid clinicopathologic entity?. A study of 30 cases.
Cáncer, 24 (1969), pp. 876-888
[12.]
G. Nash, P.C. Langlinais, K.A. Greenawald.
Alveolar cell carcinoma: Does it exist?.
Cancer, 29 (1972), pp. 322-326
[13.]
R.R. Miller, B. Nelems, K.G. Evans, N.L. Muller, D.N. Ostrow.
Glandular neoplasia of the lung. A proposed analogy to colonic tumors.
Cancer, 61 (1988), pp. 1.009-1.014
[14.]
G. Singh, S.L. Katyal, N.G. Ordonez, et al.
Type II. pneumocytes in pulmonary tumors Implications for histogenesis.
Arch Pathol Lab Med, 108 (1984), pp. 44-48
[15.]
J. Jacques, W. Currie.
Bronchio-alveolar carcinoma: A Clara cell tumor?.
Cancer, 40 (1977), pp. 2.171-2.180
[16.]
C.A. Axiotis, T.A. Jennings.
Observations on bronchio-alveolar carcinomas with special emphasis on localized lesions. A clinicopathological ultrastructural and immunohistochemical study of 11 cases.
Am J Surg Pathol, 12 (1988), pp. 918-931
[17.]
W.L. Watson, A. Farpour.
Terminal bronchiolar of “alveolar cell” cancer of the lung: tho hundred sixty five cases.
Cáncer, 19 (1966), pp. 776-780
[18.]
R.D. Montgomery, G.A. Stirling, N.A. Hamer.
Bronchiolar carcinoma in progressive systemic sclerosis.
[19.]
V.U. Lutwyche.
Another presentation of fibrosing alveolitis and alveolar cell carcinoma.
Chest, 70 (1976), pp. 292-293
[20.]
N.C. Delarue, W. Anderson, D. Sanders, J. Star.
Bronchioloalveolar carcinoma: a reappraisal after 24 years.
Cancer, 29 (1972), pp. 90-97
[21.]
C.H. Hill.
A bronchioalveolar carcinoma: a review.
[22.]
O.T. Clagett, T.H. Alien, W.S. Payne, L.B. Woolner.
The surgical treatment of pulmonary neoplasms: a 10-year experience.
J Thorac Cardiovasc Surg, 48 (1964), pp. 391-400
[23.]
D. Schraufnagel, A. Peloquin, J.A.P. Paré, N.S. Wang.
Differentiating bronchioalveolar carcinoma from adenocarcinoma.
Am Rev Respir Dis, 125 (1982), pp. 74-79
[24.]
M.J. Marzano, T. Deschler, R.A. Mintzer.
Alveolar cell carcinoma.
Chest, 86 (1984), pp. 123-128
[25.]
M.B. Rosenblatt, J.R. Lisa, F. Collier.
Primary and metastatic bronchio-alveolar carcinoma.
Dis Chest, 52 (1967), pp. 147-152
[26.]
K.H. Antman.
Current concepts: malignant mesothelioma..
Engl N. J. Med, 303 (1980), pp. 200-202
[27.]
L.C. Tao, N.C. Delarue, D. Sanders, G. Weisbrod.
Bronchioalveolar carcinoma: a correlative clinical and cytologic study.
Cancer, 42 (1978), pp. 2.759-2.767
[28.]
A.I. Spriggs, M. Cole, M.S. Dunnill.
Alveolar-cell carcinoma: a problem in sputum cytodiagnosis.
J Clin Pathol, 35 (1982), pp. 1.370-1.379
[29.]
C.S. Foster.
Mucus-secreting “alveolar cell” tumor of the lung: a histochemical comparison of tumours arising within and outside the lung.
Histopathology, 4 (1980), pp. 567-577
Copyright © 1991. Sociedad Española de Neumología y Cirugía Torácica
Archivos de Bronconeumología
Article options
Tools

Are you a health professional able to prescribe or dispense drugs?