Journal Information
Vol. 41. Issue 5.
Pages 290-292 (May 2005)
Share
Share
Download PDF
More article options
Vol. 41. Issue 5.
Pages 290-292 (May 2005)
Case Reports
Full text access
Acute Respiratory Distress Syndrome Caused by Pulmonary Nocardiosis in a Patient With Systemic Lupus Erythematosus
Visits
4802
J. Ferreres Francoa,
Corresponding author
jferreres@ono.es

Correspondence: Dr. J. Ferreres Franco. Servicio de Medicina Intensiva. Hospital Clínico Universitario de Valencia. Avda. Blasco Ibáñez, 15. 46010 Valencia. España
, J. Blanquer Olivasa, R. Dosdá Muñozb, N. Carbonell Monleóna, E. Moreno Claria, E. Pérez Sanchoa
a Servicio de Medicina Intensiva, Hospital Clínico Universitario de Valencia, Valencia, Spain
b Servicio de Radiología, Hospital Clínico Universitario de Valencia, Valencia, Spain
This item has received
Article information
Abstract
Bibliography
Download PDF
Statistics

Nocardia is a gram-positive bacillus that infects mainly immunodepressed patients. Its association with lupus erythematosus has been described only occasionally and we have found no reports in the literature of an association between lupus and acute respiratory distress syndrome due to pulmonary nocardiosis. We present such a case and discuss the mechanisms that make this lung infection so virulent as well as its epidemiological and microbiological characteristics, clinical presentation, diagnosis, and treatment.

Key Words:
Nocardia
Pulmonary nocardiosis
Systemic lupus erythematosus
Acute respiratory distress syndrome

Nocardia es una bacilo grampositivo que infecta principalmente a pacientes inmunodeprimidos. Su asociación con el lupus eritematoso sistémico se ha descrito pocas veces, y en la bibliografía médica revisada no hemos encontrado ningún caso asociado al síndrome de distrés respiratorio agudo por una nocardiosis pulmonar. A partir de un caso clínico se realiza una descripción de los mecanismos de virulencia de esta bacteria, así como de las características epidemiológicas, microbiológicas, forma de presentación clínica y procedimientos diagnósticos y terapéuticos de esta entidad.

Palabras clave:
Nocardia
Nocardiosis pulmonar
Lupus eritematoso sistémico
Síndrome de distrés respiratorio agudo
Full text is only aviable in PDF
REFERENCES
[1]
KP Leong, NW Tee, WM Yap, TS Chee, ET Koh.
Nocardiosis in patients with systemic lupus erythematosus. The Singapore Lupus Study Group.
J Rheumatol, 27 (2000), pp. 1306-1312
[2]
CC Mok, KY Yuen, CS Lau.
Nocardiosis in systemic lupus erythematosus.
Semin Arthritis Rheum, 26 (1997), pp. 675-683
[3]
AY Lee, PR Ogershok, ME Weisse.
Persistent pneumonia in a boy with systemic lupus erythematosus.
Clin Pediatr, 41 (2002), pp. 443-446
[4]
P Vachvanichsanong, P Pruekprasert, P Dissaneewate.
Non-fatal septicaemic Nocardia asteroides in a girl with systemic lupus erythematosus.
Eur J Pediatr, 161 (2002), pp. 222-223
[5]
P Mc-Nab, C Fuentealba, F Ballesteros, D Pacheco, M Álvarez, J Dabanch, et al.
Infección de Nocardia asteroides en un paciente con lupus eritematoso sistémico.
Rev Med Chil, 128 (2000), pp. 526-528
[6]
BL Beaman, BeamanL.
Nocardia species: host-parasite relationships.
Clin Microbiol Rev, 7 (1994), pp. 213-264
[7]
I Lerner Philip.
Nocardiosis.
Clin Inf Dis, 22 (1996), pp. 891-905
[8]
GA Filice, DE Niewoehner.
Contribution of neutrophils and cell-mediated immunity to control of Nocardia asteroides in murine lungs.
J Infect Dis, 156 (1987), pp. 113-121
[9]
MJ Unzaga, A Gaafar, R Cisterna.
Infección pulmonar por Nocardia nova.
Arch Bronconeumol, 39 (2003), pp. 478-480
[10]
R Pifarre, B Teixido, M Vila, M Durán, JM García, J Morera.
Nocardiosis pulmonar como causa de imagen radiológica en “sueltade globos”.
Arch Bronconeumol, 37 (2001), pp. 511-512
[11]
PR Georghiou, ZM Blacklock.
Infection with Nocardia species in Queensland. A review of 102 clinical isolates.
Med J Aust, 156 (1992), pp. 692-697
[12]
DL Palmer, RL Harvey, JK Wheeler.
Diagnostic and therapeutic considerations in Nocardia asteroides infection.
Medicine (Baltimore), 53 (1974), pp. 391-401
[13]
DP Kontoyiannis, K Ruoff, DC Hooper.
Nocardia bacteremia. Report of 4 cases and review of the literature.
Medicine (Baltimore), 77 (1998), pp. 255-267
[14]
R Menéndez, PJ Cordero, M Santos, M Gobernado, V Marco.
Pulmonary infection with Nocardia species: a report of 10 cases and review.
Eur Respir J, 10 (1997), pp. 1542-1546
[15]
K Tsushima, T Koizumi, H Aoki, K Furuta, K Fujimoto, K Kubo.
A case of acute respiratory distress syndrome caused by systemic nocardiosis.
Respiration, 67 (2000), pp. 591-592
[16]
L Schulman, Y Enson.
Nocardia pneumonitis and the adult respiratory distress syndrome.
Am J Med Sci, 293 (1987), pp. 315-319
[17]
JJ Marini, L Gattinoni.
Ventilatory management of acute respiratory distress syndrome: a consensus of two.
Crit Care Med, 32 (2004), pp. 250-255
[18]
J Blanquer, J Ferreres, M Blasco.
Distrés respiratorio agudo.
Arch Bronconeumol, 36 (2000), pp. 21-27
Copyright © 2005. Sociedad Española de Neumología y Cirugía Torácica (SEPAR)
Archivos de Bronconeumología
Article options
Tools

Are you a health professional able to prescribe or dispense drugs?