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Journal Information
Vol. 25. Issue 1.
Pages 1-2 (January - February 1989)
Vol. 25. Issue 1.
Pages 1-2 (January - February 1989)
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Activadores de los canales de potasio: ¿una nueva generacion de broncodilatadores?
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J. Cortijo Gimeno
Departamento de Farmacología y Farmacotecnia. Facultad de Medicina. Universidad de Valencia
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Bibliografia
[1.]
J.C. Clapham, C. Wilson.
Anti-spasmogenic and spasmolytic effects of BRL 34915: A comparison with nifedipine and nicorandil.
J Auton Pharmac, 7 (1987), pp. 1-10
[2.]
K.M. Bray, D.T. Newgreen, R.C. Small, J.S. Southertoh, S.G. Taylor, S.W. Weir, A.H. Weston.
Evidence that mechanism of the inhibitory action of pinacidil in rat and guinea-pig smooth muscle differs from that of glyceryl trinitrate.
Br J Pharmac, 91 (1987), pp. 421-429
[3.]
T. Inoue, Y. Kanmura, K. Fujisawa, T. Itoh, H. Kuriyama.
Effects of 2-nicotinamido ethyl nitrate (nicorandil) and its derivates on smooth muscle cells of the canine mesenteric artery.
J Pharmac Exp Ther, 229 (1984), pp. 793-802
[4.]
K. Schmidt, R. Reich, W.R. Kukovetz.
Stimulation of coronary guanylate cyclase by nicorandil as a mechanism of its vasodilating action.
J Cyc Nuc Res, 10 (1985), pp. 43-53
[5.]
S.L. Alien, R.W. Foster, G.P. Morgan, R.C. Small.
The relaxant action of nicorandil in guinea-pig isolated trachealis.
Br J Pharmac, 87 (1986), pp. 117-127
[6.]
S.L. Alien, J.P. Boyle, J. Cortijo, R.W. Foster, G.P. Morgan, R.C. Small.
Electrical and mechanical effects of BRL 34915 in guinea-pig isolated trachealis.
Br J Pharmac, 89 (1986), pp. 395-405
[7.]
J.S. Southerton, S.G. Taylor, S.W. Weir, A.H. Weston.
An investigation into the mechanism of action of pinacidil in rat blood vessels.
Br J Pharmac, 90 (1987), pp. 126P
[8.]
E. Suematsu, M. Hirata, A.H. Kuriya.
Effects of cAMP and cGMP-dependent protein kinase and calmodulin on Ca 2+ uptake by highly purified sarcolemal vesiclers of vascular smooth muscle.
Biochem Biophys Acta, 773 (1984), pp. 83-90
[9.]
S.G. Taylor, J.S. Southerton, A.H. Weston, J.R.J. Baher.
Endothelium dependent effects of acetylcholine on membrane potential, potassium flux and cyclic GMP concentrations in rat aorta: a comparison with sodium nitroprusside and the potassium channel opener, BRL 34915.
Br J Pharmac, 94 (1988), pp. 853-863
[10.]
J. Cortijo, R.W. Foster, R.C. Small.
Differentiation of calcium antagonists with respect to their effects in normal and skinned taenia caeci preparations.
J Pharm Pharmacol, 39 (1987), pp. 283-289
[11.]
J. Cortijo, J.S. Dixon, R.W. Foster, R.C. Small.
Influence of some variables in the Triton X-100 method of skinning the plasmalemmal membrane from guinea pig trachealis muscle.
J Pharmacol Methods, 18 (1987), pp. 253-266
[12.]
S.L. Alien, J. Cortijo, R.W. Foster, G.P. Morgan, R.C. Small, A.H. Weston.
Mechanical and electrical aspects of the relaxant action of aminophylline in guinea pig isolated trachealis.
Br J Pharmac, 88 (1986), pp. 473-483
[13.]
M.J. Vandenburg, S. Arr Woodward, M. Hassein, P. Stewart-Long, T.C.G. Tasker.
Potassium channel activators lower blood pressure; an initial study of BRL 34915 in hypertensive patients.
J Hypert, 4 (1986), pp. S166-S167
[14.]
H. Araki, N. Hayata, J.C. Matsuguchi, M. Nakamura.
Effects of nicorandil on rest and effort angina unresponsive to combination therapy with a calcium antagonist and oral nitrate.
Clin Therap, 9 (1987), pp. 174-182
[15.]
D. Angersbach, C.D. Nicholson.
The effect on the novel antihypertensive agent BRL 34915 on the nutritional blood flow of rat chronically ischaemic muscle.
Naunyn Schiedeberg's Arch Pharmac, 329 (1985), pp. R61
[16.]
D.R. Buckle, J. Bumstead, G.D. Clarke, J.F. Taylor, S.C. Taylor.
Reversal of agonist-induced bronchoconstriction in the guinea-pig by the potassium channel activator BRL 34915.
Br J Pharmac, 92 (1987), pp. 744P
[17.]
A. Baird, T.C. Hamilton, D.H. Richards, T. Tasker, A.J. Williams.
Inhibition of histamine induced bronchoconstriction in normal healthy volunteers by a potassium channel activator BRL 34915.
Br J Clin Pharmac, 25 (1988), pp. 114P
[18.]
B.E. Davies, K.M. Dierdorf, W.H. Eckl, W.H. Greb, G. Mellows, T. Thomsen.
The pharmacokinetics of cromakalim (BRL 34915), a new antihypertensive agent in healthy male subjects.
Br J Clin Pharmac, 25 (1988), pp. 136P
Copyright © 1989. Sociedad Española de Neumología y Cirugía Torácica