Journal Information
Vol. 11. Issue 4.
Pages 128-133 (October - December 1975)
Share
Share
Download PDF
More article options
Vol. 11. Issue 4.
Pages 128-133 (October - December 1975)
Full text access
Volumenes pulmonares y gasometria arterial en el enfisema pulmonar
Pulmonary volumes and arterial gasometry in pulmonary emphysema
Visits
5434
J. Martínez González del Río, J. Pérez Guerrero, F. Lahoz Navarro, A. Sastre Castillo, F. Marín Núñez, E. Alvarez Cuesta, A. López Encuentra, M. Lorenzo Cruz
Departamento de Alergologia y Terapéutica Respiratoria. Fundación Jiménez Díaz. Madrid
This item has received
Article information
Abstract
Bibliography
Download PDF
Statistics
Resumen y conclusiones

Hemos analizado 36 enfermos de enfisema clínico, de los cuales 14 eran puros (tipo A) y 22 tenían bronquitis asociada (tipo A + B).

De las diferentes determinaciones practicadas, resaltamos las siguientes conclusiones.

1. Acusada obstrucción bronquial con insuflación pulmonar intensa, sin diferencia significativa entre ambos grupos con descenso de la C.V. al 70%.

2. Muy escasa reversibilidad de la obstrucción bronquial tras la inhalación de broncolíticos, algo más mani los casos, discretamente mayor en el grupo A + B.

3. Moderada hipoxernia en todos fiesta en el groupo A + B.

4. Objetivamente hipercapnia significativa (PaCO2< 50mm de Hg) en el 30% de nuestra casuística, siendo más frecuente en el grupo A + B.

5. Con excepción de un caso, todos nuestros enfermos presentaban un pH normal o ligeramente elevado, sin diferencias entre ambos grupos.

6. Tras el esfuerzo: 1) PaO2 ascendió en más de la mitad de los enfermos de ambos grupos; 2) PaCO2 se incrementó con mayor frecuencia e intensidad en el tipo A + B; 3) En la tercera parte de nuestra casuística se elevan simultáneamente ambos parámetros gasométricos.

Summary

The authors have analyzed 3 5 patients with clinical emphysema; 14 with pure emphysema (tipe A) and 22 with associated bronchitis (type A+B).

Of the different determinations carried out, the authors emphasize the following conclusions.

1. Accused bronchial obstruction with intense pulmonary insufflation, with no significant difference be- tween both groups and with decrease of the Vital Capacity to 70%.

2. Very scarce reversibility of the bronchial obstruction after inhalation of broncholithics, somewhat more manifest in the group A + B.

3. Moderate hypoxemia in all the cases, discreetly greater in the group A+B.

4. The authors found significant hypercapnia (PaCO2 50mm g) in 30% of their cases, being more frequent in the group A+B.

5. With the exception ofone case, all the patients had a normal or slightiy elevated pH, with no differences between both groups.

6. After effort: 1) PaO2 increased in more than half of the patients of both groups; 2) PaCO2 increased with greater frequency and intensity in the type A+B; 3) In one third of the cases both gasometric parameters were elevated simultaneouisy.

Full text is only aviable in PDF
Bibliografia
[1.]
Ciba guest report symposium.
Terminology Definitions and classifications of chronic pulmonary emphysema and related conditions.
Thorax, 14 (1959), pp. 286
[2.]
D.V. Bates, P.T. Macklem, R.V. Christie.
Respiratory Function in disease.
2.a Ed, W.B. Saunders. Co, (1971),
[3.]
B. Burrows, C.M. Fletgher, B.E. Heard, N.L. Jones, J.S. Wootliff.
The emphisematous and bronchial types of chronic airways obstruction: A clinicopathological study of patients in London and Chicago.
Lancet, 1 (1966), pp. 830
[4.]
J.C. Leopold, J. Gouh.
The centrilobular form of hypertrophic emphysema and its relations to chronic bronchitis.
Thorax, 12 (1957), pp. 219
[5.]
G. Simon.
Radiology of Emphysema.
Clin. Radiol, 15 (1964), pp. 293
[6.]
R. Nairn, F.J. Prime, G. Simons.
Association between radiológical findings and total and regional function in emphysema.
Thorax, 24 (1969), pp. 218
[7.]
Thurlbeck, W.M., Fraser, R.G. y Bates, D.V. Progress in Research in Emphysema and chronic bronchitis. Vol. 2.º Edit. Mitchel.
[8.]
E.S. Nash, W.A. Briscoe, A. Cournand.
The relation ship between clinical and Physiological findings in chronic obstructive disease of the lungs.
Med. Thorac, 22 (1965), pp. 305
[9.]
R.C. Kory, R. Callahan, H.G. Boren, J.C. Syner.
The veterans Administracion army cooperative study of pulmonary function I. Clinical spirometry in normal men.
Am. J. Med, 30 (1961), pp. 243
[10.]
J.B. Cotes, J. Meade.
Lung function: Assessment and Aplication in Medicine.
2.a ed, Blackwell Scientific Publications, Ltd, (1968),
[11.]
R.E. Forster, J.E. Cohn, W.A. Briscon, W.S. Blaskemore, R.L. Riley.
A modification of the Krogh carbon monoxide Breath Holding technique for estimating the diffusing capacity of the lung. A comparison with three other methods.
J. Clin. Invest, 34 (1955), pp. 1.417
[12.]
A. Krogh, M. Krogh.
On the rate of diffusion of carbonic oxide into the lungs of man.
Scand. Arch. F. Physiol, 23 (1909), pp. 236
[13.]
C.A. Ogilvie, R.E. Forster, W.S. Blakemore, J.W. Morton.
A standard died breath holding techique for the clinical measurement of the difussing capacity of the lung for carbon monoxide.
J. Clin. Invest, 361 (1957), pp. 1
[14.]
W.F. Van Ganse, B.G. Farris Jr., J.E. Cotes.
Cigarette smoking and Pulmonary diffussing Capacity.
Am. Rev. Resp Dis, 105 (1972), pp. 30
[15.]
P. Astrup, K. Jorgensen, O. Slggaard Andersen, K. Engel.
Acilbase metabolism. A. new approach.
[16.]
A. Sorbini, V. Grassi, E. Solinas, G. Muiesan.
Arterial oxygen tension in relation tocage in healthy subjects.
Respiration, 25 (1968), pp. 3
[17.]
P.F. Scholander.
Analyzer for accurate estimation of respiratory gases in one half cubic centimeter.
J. Biol Chem, 167 (1947), pp. 235
[18.]
K. Mellemgaard.
Alveolar-arterial oxygen difference: size and components in normal man.
Acta. Physiol. Scad, 67 (1966), pp. 10
[19.]
G. Simón, N.B. Pride, N.L. Jones, A.C. Ralmond.
Relations between Abnormalities in the Chest Radiograph and Changes in Pulmonary Function in Chronic Bronchitis and Enphysema.
Thorax, 28 (1973), pp. 15
[20.]
G.W. Snedecor, W.G. Cochran.
Statistical Methods.
6.a Ed, lowe State Univ. Press, (1967),
[21.]
R.A. Fisher, E. Yates.
Statistical tables for Biological.
Agricultural and Medical Research Oliverand Boyd. Edinburgo, (1967),
[22.]
D.V. Bates, J.M.S. Knott, R.V. Christie.
Respiratory function in emphysema in relation to prognosis.
Quart J Med, 25 (1956), pp. 137
[23.]
E de F. Baldwin, A. Cournand, D.W. Richards Jr..
Pulmonary insufficiency: III a Study of 122 cases of pulmonary emphysema.
Medicine, 28 (1949), pp. 201
[24.]
M.H. Williams Jr., L.R. Zohman.
Cardiopulmonary function in chronic obstructive emphysema.
Am Rev. Resp. Dis, 80 (1959), pp. 689
[25.]
S. Watanabe, M. Mitchel, A.D. Benzetti.
Correlation of structure and function in chronic pulmonary emphysema.
Am Rev. Resp. Dis, 92 (1965), pp. 221
[26.]
W.M. Thurlbeck, J.A. Henderson, R.C. Fraser, D.V. Bates.
Chronic obstructive lung disease: a comparison between clinical Roentgenologic, functional and morphologic criteria in chronic bronchitis emphysema, asthma and bronchiectasis.
Medicine, 49 (1970), pp. 81
[27.]
D.E. Jenjins, D. Greenberg, S.F. Boushy, J.I. Schweppe, R.M. O’Neal.
Correlation of morphologic emphysema with pulmonary function parameters.
Trans. Assoc. Amer. Physicians, 78 (1965), pp. 218
[28.]
B. Burrows, D.H. Midrn, C.M. Fletcher, N.L. Jones.
Clinical types of chronic obstructive lung disease in London and Chicago. A study of 100 patients.
Am. Rev. Resp. Dis, 90 (1964), pp. 14
[29.]
T.L. Petty, R. Meircort, S. Ryan, T. Vincent, G.S. Filley, R.S. Mitchel.
The functional and bronchographic evaluation of postmorten human lung: Clinical physiologic, roentgenologic and pathologic correlations in normal subjects and patients with emphysema and chronic bronchitis.
Am Rev. Resp. Dis, 92 (1965), pp. 450
[30.]
E. León, F. Galland, V.M. Alastrine.
Evolución de las alteraciones anatomofuncionales del enfisema pulmonar obstructivo.
Arch. Inst. Card. Mex, 41 (1971), pp. 161
[31.]
R.G. Fraser, J.A.P. Pare.
Diagnosis of diseases of the chest 2a.
W.B. Saunders Co, (1970),
[32.]
A. Hurtado, N.L. Kaltreiderr, W.W. Fray, W.D. Brooks, A. Mccann.
Studies of total pulmonary capacity and its subdivisions VI observations on cases of obstructive pulmonary emphysema.
J. Clin. Invest, 13 (1934), pp. 1.027
[33.]
H.C. Sweet, J.P. Wyatt, P.W. Kinsella.
Correlations of lungs macrosections with pulmonary emphysema.
Am. J. Med, 29 (1960), pp. 277
[34.]
H.C. Sweet, J.P. Wyatt, Fritsch, P.W. Kinsella.
Panlobular and centrilobular emphysema Correlation of clinical finding with pathological patterns.
Ann. Intern.Med, 55 (1961), pp. 565
[35.]
G.C. Leiner, S. Abramowitz, M.J. Small.
The vital capacity in pulmonary emphysema.
Ann. Intern. Med, 60 (1964), pp. 61
[36.]
P.C. Pratt, G.A. Klugh.
A technique for the study of ventilatory capacity compliance, and residual volume of excised lungs and for fixation, drying and serial sectionings in the inflated state.
Am. Rev. Resp. Dis, 83 (1961), pp. 690
[37.]
R.D. Miller, W.S. Fowler, H.F. Helmhole.
Relative volume and venilation of the two lungs with change to the lateral decubitus position.
J. Lab Clin. Med, 47 (1956), pp. 297
[38.]
N.L. Jones.
Pulmonary gas exchange exercise in patients with chronic air way obstruction.
Clin. Sci, 4 (1966), pp. 39
[39.]
G.E. Enmanuel, F. Moreno.
Distribution of ventilation and blood now during excercise in emphysema.
J. Appl. Physiol, 21 (1966), pp. 1.532
[40.]
J.E. Cohn, H.D. Donoso.
Excercise and intrapulmonary ventilation perfusion relationships in chronic obstructive airway disease.
Am. Rev. Resp. Dis, 95 (1967), pp. 1.015
[41.]
P.H. Rossier, A.D. Buhlmann, K. Wissinger.
Respiration: Physiologic principles and their clinical applications.
C.V. Mosby Co, (1960),
[42.]
G.F. Filley.
Pulmonary ventilation and the oxygen cost of exercise in emphysema..
Trans. Amer, Clin. Climat. A, 70 (1958), pp. 113
Copyright © 1975. Sociedad Española de Neumología y Cirugía Torácica
Archivos de Bronconeumología
Article options
Tools

Are you a health professional able to prescribe or dispense drugs?