Journal Information
Vol. 60. Issue 5.
Pages 269-278 (May 2024)
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Vol. 60. Issue 5.
Pages 269-278 (May 2024)
Original Article
N-acetylcysteine Treatment in Chronic Obstructive Pulmonary Disease (COPD) and Chronic Bronchitis/Pre-COPD: Distinct Meta-analyses
Alberto Papi, Franco Alfano, Tommaso Bigoni, Lorenzo Mancini, Amal Mawass, Federico Baraldi, Cristina Aljama, Marco Contoli, Marc Miravitlles
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Abstract
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Highlights

  • Treatment effects on PROs in chronic bronchitis (CB) with/out COPD are scarcely known.

  • N-acetylcysteine (NAC) improve symptoms and/or QoL in studies conducted in CB.

  • NAC reduce exacerbations in studies conducted in subjects with CB.

  • Similarly, NAC reduce exacerbations and improve symptoms and/or QoL in COPD studies.

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