Morfología de la vertiente espiratoria de la curva de flujo-volumen en sujetos sanos, fumadores y no fumadores

Carrizo, S.J.; Marín, J.M.

doi:10.1016/S0300-2896(15)31168-6

Archivos de Bronconeumología

ISSN: 0300-2896

Archivos de Bronconeumologia is an international journal that publishes original studies whose content is based upon results of research initiatives dealing with several aspects of respiratory medicine including epidemiology, respiratory physiology, pathophysiology of respiratory diseases, clinical management, thoracic surgery, pediatric lung diseases, respiratory critical care, respiratory allergy and translational research. Other types of articles such as editorials, reviews, and different types of letters are also published in the journal. Additionally, the journal expresses the voice of the following scientific societies: the Spanish Respiratory Society of Pneumology and Thoracic Surgery (SEPAR; https://www.separ.es/), the Latin American Thoracic Society (ALAT; https://alatorax.org/), and the Iberian American Association of Thoracic Surgery (AIACT; http://www.aiatorax.com/).

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Vol. 29. Issue 8.

Pages 391-396 (November - December 1993)

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Pages 391-396 (November - December 1993)

DOI: 10.1016/S0300-2896(15)31168-6

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Morfología de la vertiente espiratoria de la curva de flujo-volumen en sujetos sanos, fumadores y no fumadores

Shape of the maximal expiratory flow-volume curve in healthy subjects, smokers and non smokers

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S.J. Carrizo*, J.M. Marín

Sección de Neumología. Hospital Miguel Servet. Zaragoza

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Para caracterizar las implicaciones de los cambios de la morfología de la curva flujo-volumen en su vertiente espiratoria sobre sujetos sanos, se han estudiado prospectivamente 150 personas: edad 32±12; varones/mujeres 67/83; fumadores (F)/no fumadores (NF) 63/87. Ningún sujeto padecía enfermedad crónica incluyendo neumopatías. Tras historia y exploración clínica detalladas, incluyendo cuestionario epidemiológico de semiología respiratoria, se practicó espirometría con curva de flujo-volumen y se determinó en ésta la morfología de la vertiente espiratoria de la curva de flujo-volumen (MEFV) mediante el cálculo del ángulo beta. Los valores medios de función pulmonar fueron similares en ambos grupos (F y NF). Los NF no demuestran ningún parámetro anormal, mientras que 4 F asintomáticos (11%) y 8 F (15%) con algún síntoma respiratorio presentan algún parámetro fuera del rango de normalidad. El ángulo beta fue inferior a 180° (LIN) en 3 F asintomáticos (8,6%) y en 41 F sintomáticos (79%). La cantidad acumulada de consumo de tabaco se relacionó inversamente con el valor de beta. Se concluye que la determinación de la MEFV presenta un valor discriminativo mayor que cualquier parámetro aislado de función pulmonar para evaluar el efecto del tabaco sobre la mecánica del vaciado pulmonar.

To determine the implications of changes in the maximal expiratory flow-volume (MEFV) curve in healthy subjects, 150 people were studied prospectively [32±12 yr; 67 men, 83 women; 63 smokers (S), 87 non smokers (NS)[. None suffered chronic or lung disease. Following physical examination and taking of a patient history that included an epidemiological questionnaire on respiratory symptoms, spirometry was carried out and a flow-volume curve plotted to determine MEFV by calculation of p angles. Means of pulmonary function were similar in both S and NS groups. No abnormal parameters were found in NS, while 4 (11%) asymptomatic S and 8 (15%) S with some respiratory symptoms presented some paremeters outside the normal range. The p angle was smaller than 180° (lower limit of normal) in 3 (8.6%) asymptomatic S and in 41 (79%) symptomatic S. Accumulated tobacco consumption was inversely correlated with the p angle. We conclude that MEFV discriminates more accurately than any other single pulmonary function parameter in assessing the effect of tobacco on the mechanics of lung emptying.

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