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Vol. 47. Issue S8.
III Foro de Neumólogos en Formación
Pages 32-36 (December 2011)
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Vol. 47. Issue S8.
III Foro de Neumólogos en Formación
Pages 32-36 (December 2011)
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Mediastinitis
Mediastinitis
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122027
Primitivo Martínez Vallinaa,
Corresponding author
p.martinezv@ono.com

Autor para correspondencia.
, Dionisio Espinosa Jiménezb, Lucía Hernández Pérezc, Ana Triviño Ramírezd
a Servicio Cirugía Torácica de Aragón, Hospital Universitario Miguel Servet, Zaragoza, España
b Servicio Cirugía Torácica, Hospital Universitario Reina Sofía, Córdoba, España
c Servicio Cirugía Torácica, Hospital de Cruces, Barakaldo, Bizkaia, España
d Servicio Cirugía Torácica, Hospital Universitario Virgen de la Macarena, Sevilla, España
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Resumen

La mediastinitis se define como la inflamación aguda o crónica de las estructuras mediastínicas. Se presenta con una baja incidencia en general. La causa aguda más frecuente es la postesternotomía derivada de la cirugía cardíaca de revascularización con ambas arterias mamarias internas, con una incidencia del 0,4-5% y una mortalidad del 16,5 al 47%, siendo el vector más frecuente el Staphylococcus aureus. La perforación esofágica normalmente iatrogénica es la segunda causa de mediastinitis aguda, vehiculizada por flora orofaríngea común, con una mortalidad del 20 al 60%, dependiendo del momento del diagnóstico. La mediastinitis necrotizante descendente es la tercera causa, siendo el foco odontógeno en un 60% el origen y el Streptococcus β-hemolítico el microorganismo causante en el 71,5%. La tomografía computarizada es la herramienta diagnóstica de imagen más adecuada. El tratamiento es prácticamente siempre quirúrgico y su precocidad determina la supervivencia de estos pacientes. El choque séptico es el factor de peor pronóstico posquirúrgico.

Palabras clave:
Mediastinitis aguda
Mediastinitis necrotizante descendente
Mediastinitis postesternotomía
Perforación esofágica
Abstract

Mediastinitis is defined as acute or chronic inflammation of the mediastinal structures and generally has a low incidence. The most frequent acute cause is sternotomy following cardiac revascularization surgery with both internal mammary arteries, with an incidence of 0.4% to 5% and a mortality of 16.5% to 47%. The most frequent vector is Staphylococcus aureus. Esophageal perforation, usually iatrogenic, is the second most frequent cause of acute mediastinitis, produced by common oropharyngeal flora, with a mortality rate of 20% to 60%, depending on the time of diagnosis. The third most frequent cause is descending necrotizing mediastinitis, the origin being an odontogenous focus in 60% and beta-hemolytic streptococcus the causative agent in 71.5% of cases. The most accurate diagnostic imaging technique is computed tomography. Treatment is almost always surgical and survival depends on its early performance. The worst postsurgical prognostic factor is septic shock.

Keywords:
Acute mediastinitis
Mediastinitis following cervical suppuration
Oesophageal perforation
Post-sternotomy mediastinitis
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Bibliografía
[1.]
H.E. Pearse.
Mediastinitis following cervical suppuration.
Ann Surg, 108 (1938), pp. 580-611
[2.]
H.C. Urschel Jr., A.N. Patel, M.A. Razzuk, S.J. Hoover, L.M. Razzuk, R. Montano.
Chronic mediastinitis.
3a ed, pp. 1529-1536
[3.]
H. Neuhof.
Acute infection of the mediastinum with special reference to mediastinal suppuration.
J Thorac Cardiovasc Surg, 6 (1936), pp. 184
[4.]
S. Endo, F. Murayama, T. Hasegawa, S. Yamamoto, T. Yamaguchi, Y. Sohara, et al.
Guideline of surgical management based on diffusion of descending necrotizing mediastinitis.
Jpn J Thorac Cardiovasc Surg, 47 (1999), pp. 14-19
[5.]
R.M. El Oakley, J.E. Wright.
Postoperative mediastinitis: Classification and management.
Ann Thorac Surg, 61 (1996), pp. 1030-1036
[6.]
A.J. Mangram, T.C. Horan, M.L. Pearson, L.C. Silver, W.R. Jarvis.
Guideline for prevention of surgical site infection, 1999. Centers for Disease Control and Prevention (CDC) Hospital Infection Control Practices Advisory Committee.
Am J Infect Control, 27 (1999), pp. 97-132
[7.]
D. Lepelletier, S. Perron, P. Bizouarn, J. Caillon, H. Drugeon, J.L. Michaud, et al.
Surgicalsitie infection after cardiac surgery: incidence, microbiology and risk factors.
Infect Control Hosp Epidemiol, 26 (2005), pp. 466-472
[8.]
M.P. Sá, D.O. Silva, E.N. Lima, R. Lima, C. de, F.P. Silva, F.G. Rueda, et al.
Postoperative mediastinitis in cardiovascular surgery postoperation. Analysis of 1038 consecutive surgeries.
Rev Bras Cir Cardiovasc, 25 (2010), pp. 19-24
[9.]
S.B. Johnson.
Esophageal trauma.
Semin Thorac Cardiovasc Surg, 20 (2008), pp. 46-51
[10.]
A.S. Estrera, M.J. Lanay, J.M. Grisham, D.P. Sinn, M.R. Platt.
Descending necrotizing mediastinitis.
Surg Gynecol Obstet, 157 (1983), pp. 545-552
[11.]
L.M. Cirino, F.M. Elias, J.L. Almeida.
Descending mediastinitis: a review.
Sao Paulo Med J, 124 (2006), pp. 285-290
[12.]
G.J. Ridder, W. Maier, S. Kinzer, C. Teszler, C. Boedeker, J. Pfeiffer.
Descending necrotizing mediastinitis. Conttemporary trends in etiology, diagnosis, management and outcome.
Ann Surg, 251 (2010), pp. 528-534
[13.]
I. Brook, E.H. Frazier.
Microbiology of mediastinitis.
Arch Intern Med, 156 (1996), pp. 333-336
[14.]
M. Deu-Martín, M. Saez-Barba, I. López-Sanz, R. Alcaraz-Peñarrocha, L. Romero-Vielva, J. Solé-Montserrat.
Factores de riesgo de mortalidad en la mediastinitis necrosante descendente.
Arch Bronconeumol, 46 (2010), pp. 182-187
[15.]
D.N. Exarhos, K. Malagari, E.G. Tsatalou, S.V. Benakis, C. Peppas, A. Kotanidou, et al.
Acute mediastinitis: spectrum of computed tomography findings.
Eur Radiol, 15 (2005), pp. 1569-1574
[16.]
M. Makeieff, N. Gresillon, J.P. Berthet, R. Garrel, L. Crampette, C. Marty-Ane, et al.
Management of descending necrotizing mediastinitis.
Laryngoscope, 114 (2004), pp. 772-785
[17.]
H.B. Schuhmacher, I. Mandelbaum.
Continuous antibiotic irrigation in the treatment of infection.
Arch Surg, 86 (1968), pp. 54-57
[18.]
R. Wettstein, D. Erni, P. Berdat, D. Rothenfluh, A. Banic.
Radical sternectomy and primary musculocutaneous flap reconstruction to control sternal osteitis.
J Thorac Cardiovasc Surg, 123 (2002), pp. 1185-1190
[19.]
J. Quiroga, J. Gualis, B. Gregorio, S. Cabanyes, A. Cilleruelo, J.L. Duque.
Utilidad de la omentoplastia en el tratamiento de la esternomediastinitis secundaria a cirugía de revascularización miocárdica.
Arch Bronconeumol, 44 (2008), pp. 113-115
[20.]
M. De Feo, R. Gregorio, A. Renzulli, G. Ismeno, G.P. Romano, M. Cotrufo.
Treatment of recurrent postoperative mediastinitis with granulated sugar.
J Cardiovasc Surg (Torino), 41 (2000), pp. 715-719
[21.]
J. Sjogren, R. Gustafsson, J. Nilsson, M. Malmsjo, R. Ingemansson.
Clinical outcome after poststernotomy mediastinitis: vacuum-assisted closure versus conventional treatment.
Ann Thorac Surg, 79 (2005), pp. 2049-2055
[22.]
P. Siondalski, L. Keita, Z. Sicko, P. Zelechowski, L. Jaworski, J. Rogowski.
Surgical treatment and adjunct hyperbaric therapy to improve healing of wound infection complications after sterno-mediastinitis.
Pneumonol Alergol Pol, 71 (2003), pp. 12-16
[23.]
S. Larsson, G. Pettersson, V. Lepore.
Esophagocutaneous drainage to treat late and complicated esophageal perforation.
Eur J Cardiothorac Surg, 5 (1991), pp. 579-582
[24.]
L. Kotsis, S. Kostic, K. Zubovits.
Multimodality treatment of esophageal disruptions.
Chest, 112 (1997), pp. 1304-1309
[25.]
P. Mihos, K. Potaris, I. Gakidis, D. Papadakis, G. Rallis.
Management of descending necrotizing mediastinitis.
J Oral Maxillofac Sur, 62 (2004), pp. 966-972
[26.]
K. Shimizu, Y. Otani, T. Nakano, Y. Takayasu, Y. Yasuoka, Y. Morishita.
Successful videoassisted mediastinoscopic drainage of descending necrotizing mediastinitis.
Ann Thorac Surg, 81 (2006), pp. 2279-2281
[27.]
A.D. Sherrick, L.R. Brown, G.F. Harms, J.L. Myers.
The radiographic findings of fibrosing mediastinitis.
Chest, 106 (1994), pp. 484-489
[28.]
S. Bays, C.h. Rajakaruma, E.d. Sheffield, A. Morgan.
Fibrosing mediastinitis as a cause of superior vena cava syndrome.
Eur J Cardiothorac Surg, 26 (2004), pp. 453-455
Copyright © 2011. Sociedad Española de Neumología y Cirugía Torácica
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