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Vol. 45. Issue 5.
Pages 212-217 (May 2009)
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Vol. 45. Issue 5.
Pages 212-217 (May 2009)
Original article
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Usefulness of Radial Endobronchial Ultrasound-Guided Transbronchial Needle Aspiration for the Diagnosis of Mediastinal Lymph Nodes
Utilidad de la punción aspirativa transbronquial guiada con ultrasonografía endobronquial (USEB) radial para el diagnóstico de adenopatías mediastínicas
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Albert Sánchez-Fonta,
Corresponding author
ASanchezF@imas.imim.es

Corresponding author.
, Víctor Curulla, Iván Vollmerb, Lara Pijuanc, Ángel Gayeteb, Joaquim Geaa
a Servei de Pneumologia, Hospital del Mar-IMIM, Universitat Autònoma de Barcelona, Universitat Pompeu Fabra, CIBER (Centro de Investigación Biomédica en Red) de Enfermedades Respiratorias (CibeRes), Barcelona, Spain
b Servei de Radiodiagnòstic, Hospital del Mar-IMIM, Universitat Autònoma de Barcelona, Universitat Pompeu Fabra, CIBER (Centro de Investigación Biomédica en Red) de Enfermedades Respiratorias (CibeRes), Barcelona, Spain
c Servei d’Anatomia Patològica, Hospital del Mar-IMIM, Universitat Autònoma de Barcelona, Universitat Pompeu Fabra, CIBER (Centro de Investigación Biomédica en Red) de Enfermedades Respiratorias (CibeRes), Barcelona, Spain
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Abstract
Introduction

Transbronchial needle aspiration (TBNA) is a bronchoscopic technique that has been shown to be useful for sampling mediastinal lymph nodes. The yield of this technique can be increased by using endobronchial ultrasound (EBUS) to guide needle placement. The aim of the present study was to compare the yield of EBUS-guided TBNA to that of conventional TBNA in the analysis of mediastinal lymph nodes.

Patients and Methods

All patients undergoing either EBUS-guided or conventional TBNA for the diagnosis of mediastinal lymph nodes between January 2006 and May 2007 were studied consecutively. Histology results were used as a reference standard in patients treated surgically. In cases in which surgery was not indicated, the results of cytology or of clinical follow-up of at least 6 months duration were used.

Results

TBNA was performed in 117 patients and a total of 143 lymph nodes were punctured (mean shortest [SD] diameter, 17.9 [8] mm). The samples obtained were diagnostic in 58 patients (49.6%) and in 70 lymph nodes (49.0%). For paratracheal and hilar stations, the yield of EBUS-guided TBNA was superior to that of conventional TBNA (59.2% compared to 34.1%, P=.02).

Conclusions

Radial EBUS guidance increases the diagnostic yield of TBNA in paratracheal and hilar lymph node stations.

Keywords:
Endobronchial ultrasound (EBUS)
Transbronchial needle aspiration (TBNA)
Mediastinal lymph nodes
Staging
Lung cancer
Resumen
Introducción

La punción aspirativa transbronquial (PATb) es una técnica broncoscópica que ha demostrado ser de utilidad para la obtención de muestras citohistológicas de adenopatías mediastínicas. La ultrasonografía endobronquial (USEB) permite realizar una punción orientada e incrementar de esta forma el rendimiento de la técnica. El objetivo del presente trabajo ha sido comparar el rendimiento de la PATb guiada con USEB radial con la realizada de forma convencional, en el estudio de adenopatías mediastínicas.

Pacientes y métodos

Se incluyó consecutivamente a todos los pacientes a quienes se realizó PATb para el estudio de adenopatías mediastínicas, fuera de forma convencional o guiada con USEB radial, desde enero de 2006 hasta mayo de 2007. Se utilizó como referencia el resultado histológico en los pacientes intervenidos quirúrgicamente y el resultado de la citología y seguimiento clínico, durante un mínimo de 6 meses, en los casos en que la cirugía no estaba indicada.

Resultados

Se realizó PATb a 117 pacientes, con un total de 143 adenopatías puncionadas (diámetro menor medio ± desviación estándar: 17,9 ± 8 mm). El material obtenido permitió el diagnóstico en 58 pacientes (49,6%) y en 70 ganglios (49,0%). Para las estaciones paratraqueales e hiliares, el rendimiento de la PATb guiada con USEB radial fue superior al de la PATb convencional (un 59,2 frente a un 34,1%; p = 0,02).

Conclusiones

La USEB radial incrementa el rendimiento diagnóstico de la PATb en las estaciones ganglionares paratraqueales e hiliares.

Palabras clave:
Ultrasonografía endobronquial (USEB) radial
Punción aspirativa transbronquial (PATb)
Adenopatías mediastínicas
Estadificación
Cáncer de pulmón
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Copyright © 2009. Sociedad Española de Neumología y Cirugía Torácica
Archivos de Bronconeumología
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