Tratamiento de la agudizacion grave del asma (status asmaticus). Resultados con un tratamiento estandar

Vennera, M.aC.; Xaubet, A.; Montserrat, J.M.; Agusti Vidal, A.

doi:10.1016/S0300-2896(15)32348-6

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Archivos de Bronconeumologia is an international journal that publishes original studies whose content is based upon results of research initiatives dealing with several aspects of respiratory medicine including epidemiology, respiratory physiology, pathophysiology of respiratory diseases, clinical management, thoracic surgery, pediatric lung diseases, respiratory critical care, respiratory allergy and basic research. Other types of articles such as editorials, reviews, and different types of letters are also published in the journal. Additionally, the journal expresses the voice of the following scientific societies: the Spanish Respiratory Society of Pneumology and Thoracic Surgery (SEPAR; https://www.separ.es/), the Latin American Thoracic Society (ALAT; https://alatorax.org/), and the Iberian American Association of Thoracic Surgery (AIACT; http://www.aiatorax.com/).

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Vol. 18. Issue 4.

Pages 175-179 (July - August 1982)

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Pages 175-179 (July - August 1982)

DOI: 10.1016/S0300-2896(15)32348-6

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Tratamiento de la agudizacion grave del asma (status asmaticus). Resultados con un tratamiento estandar

Treatment of acute asthmatic attacks (status asthmaticus): the results obtained with standard treatment

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M.aC. Vennera, A. Xaubet, J.M. Montserrat, A. Agusti Vidal

Servicio de Neumología y Alergia Respiratoria. Hospital Clínico y Provincial. Barcelona

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Resumen

Se analiza la respuesta a un tratamiento estándar realizado con teofilina, salbutamol y corti coides, en un grupo de asmáticos ingresados por agudización grave de su enfermedad (AGA gra do II).

En todos ellos se observó una mejoría clínica y/o funcional, pudiendo ser dados de alta al nove no día del tratamiento. Se observó un período libre entre tres y cinco días hasta que la mejoría comen zaba a ser evidente.

Según las valoraciones de PEF (Peak Expiratory Flow), se obtuvieron tres modelos de recuperación: uno rápido hacia la normalidad (A), otro lento, también hacia la normalidad (B), y un tercero de recuperación incompleta (C).

Estos modelos parecen guardar relación con la edad, siendo los del grupo A significativamente menores que los del B y C.

Las pruebas funcionales efectuadas antes del al ta, demostraron la presencia de un patrón obstruc tivo de mediana intensidad en los pacientes perte necientes al modelo C.

Este diferente comportamiento deberá ser consi derado siempre que se realicen ensayos terapéuti cos en enfermos asmáticos.

Summary

The response obtained with a standard treat ment of the.ophyliine, salbutamol and corti costeroids, was studied in a group of asthmatic patients who were admitted to hospital because of acute stage II asthma attacks.

A favorable clinical or functional response —or both— was obtained in all patients, and they were discharged after the nineth treatment day. There was a stationary period between the third and fifth day before improvement became evident in all patients.

Peak expiratory flow studies showed three different modes of improvement: one with rapid response (A); one a slow response (B) and a third one with incomplete response (C); all seem age related, and the patients in group A were significantly younger than in the other two groups.

Functional tests done before discharging the patients showed those in group C to have a médium intensity pattern of obstruction. These different response patterns must be taken into account when considering the therapeutical management of asthmatic patients.

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Bibliografia

[1.]

J.S. Bodes.

Status asthmaticus.

Med Clin N Am, 54 (1970), pp. 493-509

Medline

[2.]

C. Picado.

Obstrucción reversible de vías aéreas: asma bronquial.

Medicine(2.a serie), 43 (1980), pp. 13-41

[3.]