Journal Information
Vol. 44. Issue 3.
Pages 170-172 (January 2008)
Share
Share
Download PDF
More article options
Vol. 44. Issue 3.
Pages 170-172 (January 2008)
Case Reports
Full text access
Severe Pulmonary Hypertension and Takayasu Arteritis
Visits
6242
Ignasi Garcia-Olivé
Corresponding author
38826igo@comb.es

Correspondence: Dr I. García Olivé Servei de Pneumologia, Hospital Germans Trias i Pujol Ctra. del Canyet, s/n 08916 Badalona, Barcelona, Spain
, Maria Sol Prats Bardají, Susana Calvo Pascual, Dan Sánchez Berenguer, Eduard Valverde Forcada, Joan Ruiz-Manzano
Servei de Pneumologia, Hospital Germans Trias i Pujol, Badalona, Barcelona, Spain
This item has received
Article information
Abstract
Bibliography
Download PDF
Statistics

Takayasu arteritis is an inflammatory disease that affects large vessels, especially the aorta and its branches. The clinical features of the disease depend on which arteries are affected. Although pulmonary artery involvement is common, only rarely is this the main clinical manifestation. We describe the case of a young woman with dyspnea who had severe pulmonary hypertension secondary to Takayasu arteritis of the pulmonary artery. She was administered corticosteroid (methylprednisolone) and immunosuppressant (azathioprine)therapy and a stent was implanted in the left pulmonary artery. Both hemodynamic and clinical signs improved.

Key words:
Takayasu arteritis
Pulmonary hypertension
Stent

La enfermedad de Takayasu es una enfermedad inflamatoria que afecta a los grandes vasos, especialmente la aorta y sus ramas. La clínica de la enfermedad depende de la distribución de las arterias afectadas. A pesar de que la arteria pulmonar se afecta de manera habitual, rara vez es ésta la principal manifestación clínica de la enfermedad. Se describe el caso de una paciente joven con clínica de disnea que presentaba hipertensión pulmonar grave secundaria a la afectación de la arteria pulmonar, que se trató con corticoides (metilprednisolona), inmunodepresores (azatioprina) y la implantación de un stent en la arteria pulmonar izquierda, tras lo cual presentó una notable mejoría tanto hemodinámica como clínica.

Palabras clave:
Enfermedad de Takayasu
Hipertensión pulmonar
Full text is only aviable in PDF
References
[1]
SL Johnston, RJ Lock, MM Gompels.
Takayasu arteritis: a review.
J Clin Pathol, 5 (2002), pp. 481-486
[2]
WP Arend, BA Michel, DA Bloch, GG Hunder, LH Calabrese, SM Edworthy, et al.
The American College of Rheumatology 1990 criteria for the classification of Takayasu arteritis.
Arthritis Rheum, 33 (1990), pp. 1129-1134
[3]
R Moriwaki, M Noda, M Yajima, BK Sharma, F Numano.
Clinical manifestations of Takayasu arteritis in India and Japan – new classification of angiographic finding.
Angiology, 48 (1997), pp. 369-379
[4]
K Ishikawa.
Natural history and classification of occlusive thromboaortopathy (Takayasu's disease).
Circulation, 57 (1978), pp. 27-35
[5]
R Subramanyan, J Joy, KG Balakrishnan.
Natural history of aortoarteritis (Takayasu's disease).
Circulation, 80 (1989), pp. 429-437
[6]
P Liang, GS Hoffman.
Advances in the medical and surgical treatment of Takayasu arteritis.
Curr Opin Rheumatol, 17 (2005), pp. 16-24
[7]
E Lupi, G Sánchez, S Horwitz, E Gutierrez.
Pulmonary artery involvement in Takayasu's arteritis.
Chest, 67 (1997), pp. 69-74
[8]
O Brugiere, H Mal, C Sleiman, O Groussard, F Mellot, M Fournier.
Isolated pulmonary arteries involvement in a patient with Takayasu's arteritis.
Eur Respir J, 11 (1998), pp. 767-770
[9]
S Elsasser, M Soler, CT Bolliger, K Jager, U Sterger, AP Perruchoud.
Takayasu disease with predominant pulmonary involvement.
Respiration, 67 (2000), pp. 213-215
[10]
S Koyabu, N Isaka, T Yada, T Konishi, T Nakano, et al.
Severe respiratory failure caused by recurrent hemorrhage in Takayasu's arteritis.
Chest, 104 (1993), pp. 1905-1906
[11]
I Yamada, H Shibuya, O Matsubara, Y Umehara, T Makino, F Numano, et al.
Pulmonary artery disease in Takayasu's arteritis: angiographic findings.
AJR Am J Roentgenol, 159 (1992), pp. 263-269
[12]
M Castellani, M Vanoli, G Cali, GM Bacchiani, CM Origgi, EM Reschini, et al.
Ventilation-perfusion lung scan for the detection of pulmonary involvement in Takayasu's arteritis.
Eur J Nuclear Med, 28 (2001), pp. 1801-1805
[13]
B Neidhart, Kosek, LM Bachmann, C Stey.
tExertional dyspnea as initial manifestation of Takayasu's arteritis – a case report and literature review.
BMC Pulm Med, 1 (2001), pp. 3
[14]
H Shikata, S Sakamoto, Y Ueda, S Tsuchishima, T Matsubara, H Nizhizawa, et al.
Reconstruction of bilateral branch pulmonary artery stenosis caused by Takayasu's aortitis.
Circ J, 68 (2004), pp. 791-794
[15]
S Tyagi, V Mehta, R Kashyap, UA Kaul.
Endovascular stent implantation for severe pulmonary artery stenosis in aortoarteritis (Takayasu's arteritis).
Catheter Cardiovasc Interv, 61 (2004), pp. 281-285
Copyright © 2008. Sociedad Española de Neumología y Cirugía Torácica (SEPAR)
Archivos de Bronconeumología
Article options
Tools

Are you a health professional able to prescribe or dispense drugs?