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Vol. 45. Issue 9.
Pages 466-468 (September 2009)
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Vol. 45. Issue 9.
Pages 466-468 (September 2009)
Case Reports
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Pulmonary Epithelioid Hemangioendothelioma
Hemangioendotelioma epitelioide pulmonar
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Leire Azcárate Pereaa,
Corresponding author
leiazpe@hotmail.com

Corresponding author.
, Eduardo Oliveros Acebesb, Nicolás Moreno Mataa, Roberto Salomón Pérezb, Encarnación Vilalta Castelb, Federico González Aragonesesa
a Servicio de Cirugía Torácica, Hospital General Universitario Gregorio Marañon, Madrid, Spain
b Servicio de Medicina Interna, Hospital General Universitario Gregorio Marañon, Madrid, Spain
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Abstract

Epithelioid hemangioendothelioma is a multifocal tumor that rarely metastasizes. It is difficult to diagnose and is most often an incidental finding in young asymptomatic women. It has a heterogeneous radiologic pattern. The most important diagnostic information is histologic confirmation of Weibel-Palade bodies or immunohistochemistry based on specific tumor markers such as factor VIII and CD34. We report the case of a 73-year-old woman in whom multiple pulmonary nodules detected by chance in a radiograph were subsequently diagnosed as epithelioid hemangioendothelioma.

Keywords:
Pulmonary epithelioid hemangioendothelioma
Weibel-Palade bodies
CD34
Resumen

El hemangioendotelioma epitelioide es una enfermedad de difícil diagnóstico, descrita como un tumor multicéntrico y de escasa actividad metastásica, que aparece con mayor frecuencia en mujeres jóvenes asintomáticas y como un hallazgo casual. El patrón radiológico es heterogéneo. El dato más importante para su diagnóstico es la confirmación histológica de cuerpos de Weibel-Palade, o bien la inmunohistoquímica, con marcadores tumorales específicos como el factor VIII y CD34. Presentamos el caso de una mujer de 73 años en quien de forma casual se detectaron, en una imagen radiológica, nódulos pulmonares múltiples que posteriormente se diagnosticaron como esta entidad tumoral.

Palabras clave:
Hemangioendotelioma epitelioide
Cuerpos de Weibel-Palade
CD34
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