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Vol. 23. Issue 5.
Pages 245-252 (September - October 1987)
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Vol. 23. Issue 5.
Pages 245-252 (September - October 1987)
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Patogenia del enfisema pulmonar
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V. Marco
Servicio de Neumología. Hospital La Fe. Valencia
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Bibliografia
[1.]
P. Gross, M.A. Babyak, E. Tolker, M. Kaschac.
Enzymatically produced pulmonary emphysema. A preliminary report.
J Occup Med, 6 (1964), pp. 481-484
[2.]
V. Marco, D.R. Meranze, M. Yoshyda, P. Kimbel.
Papain-induced experimental emphysema in the dog.
J Appl Physiol, 33 (1972), pp. 293-299
[3.]
S. Eriksson.
Pulmonary emphysema and alpha l-antitrypsin deficiency.
Acta Med Scand, 175 (1964), pp. 197-205
[4.]
V. Marco, B. Mass, D.R. Meranze, G. Weinbaum, P. Kimbel.
Induction of experimental emphysema in dogs using leukocyte homogenates.
Am Rev Respir Dis, 104 (1971), pp. 595-598
[5.]
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Experimental emphysema induced with purifíed human neutrophil elastase Tissue localization of the instilled protease.
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[6.]
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The. size of the pool of alveolar neutrophils in normal rabbit lungs.
J Appl Physiol: Respirat Environ Exercise Physiol, 47 (1979), pp. 440-444
[7.]
V. Marco, J. Marco, G. Ocio.
Lung sequestration of polymorphonuclear leukocytes and proteolysis Influence of tobacco.
Am Rev Respir Dis, 123 (1981), pp. 220
[8.]
J.H. Dijkman, C. Franken, J.A. Kramps, C.J.L.M. Meijer.
Enzymes and enzyme-inhibitors in the small airways.
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The oxidative inactivation of human alpha 1-proteinase inhibitor: further evidence for methionine at the reactive center.
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The concentration of leukocyte elastase-alpha 1-proteinase inhibitor complex in alveolar lavage fluids from healthy human subjects.
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Levels of elastase activity in bronchoalveolar lavage fluids of healthy smokers and nonsmokers.
Am Rev Respir Dis, 127 (1983), pp. 540-544
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J.E. Gadek, G.W. Hunninghake, G.A. Fells, et al.
Validation of the alpha 1-antitrypsin hypothesis: recovery of active, connective tissue-specific proteases from the lung of PiZ patients and reversal with alpha 1-antitrypsin replacement therapy (abstract).
Clin Res, 49 (1981), pp. 550
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Familial variation of leukocyte lysosomal protease and serum alpha 1-antitrypsin as determinants in chronic obstructive pulmonary disease.
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Smoking habitats laboratory tests..
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The relationship of the peripheral leukocyte count and cigarette smoking to pulmonary function among adult men.
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Über den Einfluss des Nicotins auf das leukocytare Blutbild des Menschen.
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[18.]
P. Winkel, B.E. Statland.
The acute effect of cigarette smoking on the concentrations of blood leukocyte types in healthy young women.
Am J Clin Pathol, 75 (1981), pp. 781-785
[19.]
V. Marco, D. Nauffal, J. Gil, et al.
Polymorphonuclear leukocytes do not rise acutely in response to cigarette smoke inhaladon.
Am Rev Respir Dis, 131 (1985), pp. A213
[20.]
D. Nauffal, J. Gil, V. Marco.
Elevated blood leukocytes in smokers do not decrease in the days following stopping smoking.
Eur J Respir Dis, 69 (1986), pp. Al17
[21.]
V. Marco, F. Amaga, J. Gil, et al.
Bone-marrow germinal cells are stimulated in smokers: a possible mechanism of leukocyte elevation.
Am Rev Respir Dis, 133 (1986), pp. A54
[22.]
G. Hunninghake, J. Gadek, R. Crytal.
Human alveolar macrophage neutrophil chemotactic factor: stimuli and partial characterization.
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Alveolar macrophage-derived chemotactic factor Kinetics of in vitro production and partial characterization.
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Mechanism for the inflammatory response in primate lungs.
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[25.]
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Cigarette smoke can activate the alternative pathway of complement in vitro by modifying C3.
J Clin Invest, 75 (1985), pp. 1000-1007
[26.]
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Nicotine is chemotactic for neutrophils and enhances neutrophil responsiveness to chemotactic peptides.
Science, 233 (1984), pp. 169-171
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Chemotactic activity of elastin-derived peptides.
J Clin Invest, 66 (1980), pp. 859.862
[28.]
M. Orlowski, J. Orlowski, M. Lesser, K.H. Kilburn.
Proteolitic enzymes in bronchopulmonary lavage fluids: cathepsin B-like activity and prolyl endopeptidase.
J Lab Clin Med, 97 (1981), pp. 467-476
[29.]
A. Janoff, H. Carp.
Possible mechanism of emphysema in cigarette smokers: cigarette smoke condensate supresses proteinase inhibitors «in vitro».
Am Rev Respir Dis, 116 (1977), pp. 65-72
[30.]
A. Cantin, R.G. Crystal.
Oxidant antioxidants and the pathogenesis of emphysema.
Eur J Respir Dis, 66 (1985), pp. 7-17
[31.]
K.J.K. Johnson, J.C. Fantone, J. Kaplan, P.I. Ward.
In vivo damaged rat lungs by oxygen metabolites.
J Clin Invest, 67 (1981), pp. 983-993
[32.]
A. Janoff, H. Carp, D.K. Lee, R.T. Drew.
Cigarette smoke inhalation decreases alpha 1-antitrypsin activity in rat lung.
Science, 206 (1979), pp. 1313-1314
[33.]
J.E. Gadek, G.A. Fells, R.G. Crystal.
Cigarette smoking induces functional antiprotease deficiency in the lower respiratory tract of humans.
Science, 206 (1979), pp. 1315-1316
[34.]
P.J. Stone, J.D. Calore, S.E. McGowan, J. Bernado, G.L. Snider, C. Franzblau.
Functional alpha 1-protease inhibitor in the lower respiratory tract of cigarette smokers is not decreased.
Science, 221 (1983), pp. 1187-1189
[35.]
H. Carp, F. Miller, J. Hoidal, A. Janoff.
Alpha 1-proteinase inhibitor purified from lungs of cigarette smokers contains oxidized methionine and has decreased elastase inhibitory capacity.
Proc Natl Acad Sci USA, 779 (1982), pp. 2041-2045
[36.]
P.W. Ludwig, B.A. Schwartz, J.R. Hoidal, D.E. Niewoehner.
Cigarette smoking causes accumulation of polymorphonuclear leukocytes in alveolar septum.
Am Rev Respir Dis, 131 (1985), pp. 828-830
[37.]
M. Osman, J.O. Cantor, S. Roffman, S. Keller, G.M. Turino, I. Mandl.
Cigarette smoke impairs elastin resynthesis in lungs of hamsters with elastase-induced emphysema.
Am Rev Respir Dis, 132 (1985), pp. 640-643
[38.]
T. Cabezon, M. DeWilde, P. Herion, R. Loriau, A. Bollen.
Expression of human alpha 1-antitrypsin cDNA in the yeast Saccharomyces cerevisiae.
Proc Natl Acad Sci USA, 81 (1984), pp. 6594-6598
[39.]
G.L. Snider.
The pathogenesis of emphysema Twenty years of progress.
Am Rev Respir Dis, 124 (1981), pp. 321-324
[40.]
A.B. Cohen.
Supplement: proteases and antiproteases in the lung.
Am Rev Respir Dis, 127 (1983), pp. S2-S58
[41.]
A. Janoff, emphysema. Elastases.
Current assessment of the protease-antiprotease hypothesis.
Am Rev Respir Dis, 132 (1985), pp. 417-433
Copyright © 1987. Sociedad Española de Neumología y Cirugía Torácica
Archivos de Bronconeumología
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