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        "resumen" => "<span class="elsevierStyleSectionTitle">Introduction and Objectives</span><p class="elsevierStyleSimplePara elsevierViewall">Many studies of lung cancer survival are carried out in patients selected for certain features that usually influence prognosis favorably&#46; The objective of this study was to assess the overall survival of unselected patients with a diagnosis of lung cancer in our practice&#46;</p> <span class="elsevierStyleSectionTitle">Patients and Methods</span><p class="elsevierStyleSimplePara elsevierViewall">We studied 610 patients for whom survival information was available&#44; a population comprising 88&#37; of the 694 with lung cancer diagnosed in our hospital from 1991 through 1998&#46; The variables analyzed for their correlation with survival were age&#44; sex&#44; histology&#44; tumor-node-metastasis &#40;TNM&#41; stage&#44; treatment&#44; and time of diagnosis &#40;with patients grouped by 2-year periods&#41;&#46;</p> <span class="elsevierStyleSectionTitle">Results</span><p class="elsevierStyleSimplePara elsevierViewall">The cases of 596 men and 14 women with a mean age of approximately 67 years were studied&#46; Small cell tumors were found in 141&#44; non-small cell tumors in 447&#44; and other tissue types in 22&#46; Surgical excision was carried out on 118 &#40;19&#46;3&#37;&#41;&#44; and treatment was confined to control of symptoms for 6&#46;4&#37; of the patients with small cell tumors and 40&#46;5&#37; of those with non-small cell cancer&#46; Symptomatic treatment alone was more common for patients older than 70 years &#40;52&#46;5&#37;&#41; and less common during the last 2 years of the study period &#40;1997-1998&#58; 19&#37;&#41;&#46; Overall 5-year survival was 7&#46;9&#37; &#40;2&#46;8&#37; in small cell cancer and 9&#46;4&#37; in non-small cell cancer&#41;&#46; Survival rates were lower in patients over 70 years of age&#46; Significant differences in survival were seen for successive TNM stages&#44; with the exception of IIIA and IIIB&#46; The 1997-1998 period saw better survival rates&#44; at 40&#46;8&#37; after 1 year and 11&#46;2&#37; after 5 years&#46;</p> <span class="elsevierStyleSectionTitle">Conclusions</span><p class="elsevierStyleSimplePara elsevierViewall">The survival rates in lung cancer patients in our hospital practice are low because the rate of surgical resections is low owing to the high percentage of cases found in advanced stages&#46; Our observations are similar to those reported from other European countries&#46;</p>"
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        "resumen" => "<span class="elsevierStyleSectionTitle">Introducci&#243;n y Objetivos</span><p class="elsevierStyleSimplePara elsevierViewall">Muchos estudios sobre la supervivencia en el c&#225;ncer de pulm&#243;n se refieren a subgrupos de pacientes seleccionados por diferentes criterios que suelen influir favorablemente en la estimaci&#243;n del pron&#243;stico&#46; El objetivo de este trabajo es conocer la supervivencia global de los pacientes diagnosticados en nuestro medio&#46;</p> <span class="elsevierStyleSectionTitle">Pacientes y m&#233;todos</span><p class="elsevierStyleSimplePara elsevierViewall">De 694 pacientes diagnosticados de c&#225;ncer de pulm&#243;n en nuestro centro en el per&#237;odo 1991-1998&#44; se incluy&#243; en el estudio a 610 &#40;88&#37;&#41; con datos de supervivencia&#46; Se analizaron la edad&#44; el sexo&#44; la estirpe histol&#243;gica&#44; esta-dios&#44; tumor&#44; n&#243;dulos&#44; met&#225;stasis &#40;TNM&#41;&#44; tratamiento aplicado bienio diagn&#243;stico y su relaci&#243;n con la supervivencia&#46;</p> <span class="elsevierStyleSectionTitle">Resultados</span><p class="elsevierStyleSimplePara elsevierViewall">Se incluy&#243; en el estudio a 596 varones y a 14 mujeres&#44; con una mediana de edad de 67 a&#241;os&#46; En cuanto a la estirpe del c&#225;ncer de pulm&#243;n&#44; 141 eran microc&#237;ticos&#44; 447 no microc&#237;ticos y 22 de otra estirpe&#46; Se oper&#243; a 118 pacientes &#40;19&#44;3&#37;&#41;&#46; El 6&#44;4&#37; de los casos de c&#225;ncer de pulm&#243;n microc&#237;-tico y el 40&#44;5&#37; de los no microc&#237;ticos recibieron s&#243;lo tratamiento sintom&#225;tico&#46; &#201;ste fue m&#225;s frecuente en mayores de 70 a&#241;os &#40;52&#44;5&#37;&#41; y menos habitual durante el &#250;ltimo bienio &#40;1997-1998&#59; 19&#37;&#41;&#46; La supervivencia a los 5 a&#241;os del grupo total fue del 7&#44;9&#37; &#40;del 2&#44;8&#37; para los microc&#237;ticos y del 9&#44;4&#37; para los no microc&#237;ticos&#41;&#46; Los mayores de 70 a&#241;os tuvieron peor supervivencia&#46; Hubo diferencias significativas entre los sucesivos estadios TNM cl&#237;nico&#44; salvo entre IIIA y IIIB&#46; Los diagnosticados en el per&#237;odo 1997-1998 tuvieron mejor supervivencia &#40;un 40&#44;8&#37; al a&#241;o y un 11&#44;2&#37; a los 5 a&#241;os&#41;&#46;</p> <span class="elsevierStyleSectionTitle">Conclusions</span><p class="elsevierStyleSimplePara elsevierViewall">La supervivencia observada&#44; similar a la de otros pa&#237;ses europeos&#44; es pobre porque la tasa de resec-ciones quir&#250;rgicas es baja dado el alto porcentaje de estadios avanzados&#46;</p>"
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Vol. 40. Issue 6.
Pages 268-274 (June 2004)
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Vol. 40. Issue 6.
Pages 268-274 (June 2004)
Original Articles
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Overall Long-Term Survival in Lung Cancer Analyzed in 610 Unselected Patients
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J. Sánchez de Cos Escuín
Corresponding author
juli1949@separ.es

Correspondence: Dr. J. Sánchez de Cos Escuín. Isla de Hierro, 2, 3.°C. 10001 Cáceres. España
, C. Disdier Vicente, J. Corral Peñafiel, J.A. Riesco Miranda, M.A. Sojo González, J.F. Masa Jiménez
Hospital San Pedro de Alcántara, Cáceres, Spain
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Abstract
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Introduction and Objectives

Many studies of lung cancer survival are carried out in patients selected for certain features that usually influence prognosis favorably. The objective of this study was to assess the overall survival of unselected patients with a diagnosis of lung cancer in our practice.

Patients and Methods

We studied 610 patients for whom survival information was available, a population comprising 88% of the 694 with lung cancer diagnosed in our hospital from 1991 through 1998. The variables analyzed for their correlation with survival were age, sex, histology, tumor-node-metastasis (TNM) stage, treatment, and time of diagnosis (with patients grouped by 2-year periods).

Results

The cases of 596 men and 14 women with a mean age of approximately 67 years were studied. Small cell tumors were found in 141, non-small cell tumors in 447, and other tissue types in 22. Surgical excision was carried out on 118 (19.3%), and treatment was confined to control of symptoms for 6.4% of the patients with small cell tumors and 40.5% of those with non-small cell cancer. Symptomatic treatment alone was more common for patients older than 70 years (52.5%) and less common during the last 2 years of the study period (1997-1998: 19%). Overall 5-year survival was 7.9% (2.8% in small cell cancer and 9.4% in non-small cell cancer). Survival rates were lower in patients over 70 years of age. Significant differences in survival were seen for successive TNM stages, with the exception of IIIA and IIIB. The 1997-1998 period saw better survival rates, at 40.8% after 1 year and 11.2% after 5 years.

Conclusions

The survival rates in lung cancer patients in our hospital practice are low because the rate of surgical resections is low owing to the high percentage of cases found in advanced stages. Our observations are similar to those reported from other European countries.

Key words:
Lung cancer
Overall survival
Unselected patients
Introducción y Objetivos

Muchos estudios sobre la supervivencia en el cáncer de pulmón se refieren a subgrupos de pacientes seleccionados por diferentes criterios que suelen influir favorablemente en la estimación del pronóstico. El objetivo de este trabajo es conocer la supervivencia global de los pacientes diagnosticados en nuestro medio.

Pacientes y métodos

De 694 pacientes diagnosticados de cáncer de pulmón en nuestro centro en el período 1991-1998, se incluyó en el estudio a 610 (88%) con datos de supervivencia. Se analizaron la edad, el sexo, la estirpe histológica, esta-dios, tumor, nódulos, metástasis (TNM), tratamiento aplicado bienio diagnóstico y su relación con la supervivencia.

Resultados

Se incluyó en el estudio a 596 varones y a 14 mujeres, con una mediana de edad de 67 años. En cuanto a la estirpe del cáncer de pulmón, 141 eran microcíticos, 447 no microcíticos y 22 de otra estirpe. Se operó a 118 pacientes (19,3%). El 6,4% de los casos de cáncer de pulmón microcí-tico y el 40,5% de los no microcíticos recibieron sólo tratamiento sintomático. Éste fue más frecuente en mayores de 70 años (52,5%) y menos habitual durante el último bienio (1997-1998; 19%). La supervivencia a los 5 años del grupo total fue del 7,9% (del 2,8% para los microcíticos y del 9,4% para los no microcíticos). Los mayores de 70 años tuvieron peor supervivencia. Hubo diferencias significativas entre los sucesivos estadios TNM clínico, salvo entre IIIA y IIIB. Los diagnosticados en el período 1997-1998 tuvieron mejor supervivencia (un 40,8% al año y un 11,2% a los 5 años).

Conclusions

La supervivencia observada, similar a la de otros países europeos, es pobre porque la tasa de resec-ciones quirúrgicas es baja dado el alto porcentaje de estadios avanzados.

Palabras clave:
Cáncer de pulmón
Supervivencia global
Pacientes no seleccionados
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Copyright © 2004. Sociedad Española de Neumología y Cirugía Torácica (SEPAR)
Archivos de Bronconeumología
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