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        "resumen" => "<span class="elsevierStyleSectionTitle">Objective</span><p class="elsevierStyleSimplePara elsevierViewall">The prevalence of obstructive sleep apnea hypopnea syndrome &#40;OSAHS&#41; in the general pediatric population ranges from 1&#37; to 3&#37;&#46; However&#44; its prevalence in an unselected population of obesity and OSAHS in children diagnosed with the syndrome in a cohort of boys and girls &#40;age range&#44; 2-14 years&#41; referred to the pediatric respiratory medicine outpatient clinic at our hospital for suspected apnea&#44; snoring&#44; or both over the past 5 years&#46;</p> <span class="elsevierStyleSectionTitle">Patients and methods</span><p class="elsevierStyleSimplePara elsevierViewall">The medical history of each patient was recorded and all patients underwent a physical examination&#44; chest and nasal cavities radiography&#44; and 8-channel respiratory polygraphy during sleep&#46; the following variables were evaluated&#58; sex&#44; reason for consultation&#44; source of referral&#44; findings during upper airway examination&#44; age&#44; weight <span class="elsevierStyleItalic">z</span>-score &#40;reflecting how much a finding differs from the mean and in what direction in a normally distributed sample&#41;&#44; height <span class="elsevierStyleItalic">z</span>-score&#44; body mass index &#40;BMI&#41; <span class="elsevierStyleItalic">z</span>-score&#44; number of apneas&#44; number of hypopneas&#44; apnea index&#44; hypopnea index&#44; apnea-hypopnea index &#40;AHI&#41;&#44; oxygen saturation &#40;mean and minimum&#41; measured by pulse oximetry&#44; number of snores&#44; and snore index&#46;</p> <span class="elsevierStyleSectionTitle">Results</span><p class="elsevierStyleSimplePara elsevierViewall">Of the 400 patients studied&#44; 242 &#40;60&#46;5&#37;&#41; were male and 158 &#40;39&#46;5&#37;&#41; female&#46; the mean age was 4&#46;95 years&#46; OSAHS &#40;AHI&#8805;3&#41; was diagnosed in 298 cases &#40;74&#46;5&#37;&#41; and these patients were then studied to determine the relation between OSAHS and obesity&#46; the anthropometric distribution &#40;expressed as mean &#91;SD&#93;&#41; was as follows&#58; weight <span class="elsevierStyleItalic">z</span>-score&#44; 0&#46;37 &#40;1&#46;31&#41;&#59; height <span class="elsevierStyleItalic">z</span>-score&#44; 0&#46;23 &#40;1&#46;19&#41;&#59; BMI&#44; 17&#46;063 kg&#47;m<span class="elsevierStyleSup">2</span> &#40;2&#46;51&#41;&#59; and BMI <span class="elsevierStyleItalic">z</span>-score&#44; 1&#46;39 &#40;1&#46;36&#41;&#46; the respiratory polygraph during sleep recorded an AHI of 6&#46;56 &#40;7&#46;56&#41;&#46;</p> <span class="elsevierStyleSectionTitle">Conclusions</span><p class="elsevierStyleSimplePara elsevierViewall">No differences were observed between the height <span class="elsevierStyleItalic">z</span>-score&#44; weight <span class="elsevierStyleItalic">z</span>-score&#44; BMI <span class="elsevierStyleItalic">z</span>-score&#44; age&#44; and AHI&#46; No association between obesity and OSAHS was found in this series&#46; However&#44; studies of larger&#44; unselected populations are needed to determine if obesity is a risk factor for OSAHS in children&#46;</p>"
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        "resumen" => "<span class="elsevierStyleSectionTitle">Objetivo</span><p class="elsevierStyleSimplePara elsevierViewall">El s&#237;ndrome de apneas-hipopneas obstructivas durante el sue&#241;o &#40;SAHOS&#41; alcanza una prevalencia del 1-3&#37; en poblaci&#243;n general infantile&#46; Sin embargo&#44; en poblaci&#243;n obesa no preseleccionada la prevalencia es desconocida&#46; Para estudiar la asociaci&#243;n entre SAHOS y obesidad en ni&#241;os diagnosticados de dicho trastorno&#44; hemos analizado a una cohorte de ni&#241;os y ni&#241;as &#40;2-14 a&#241;os&#41; remitidos en los &#250;ltimos 5 a&#241;os a consulta externas de neumolog&#237;a infantile porsospecha de apneas durante el sue&#241;o&#44; ronquido o ambos&#46;</p> <span class="elsevierStyleSectionTitle">Pacientes y m&#233;todos</span><p class="elsevierStyleSimplePara elsevierViewall">A los pacientes incluidos se les realizaron anamesis&#44; exploraci&#243;n f&#237;sica&#44; radiograf&#237;a de t&#243;rax y c&#225;vum y poligraf&#237;a respiratoria durante el sue&#241;o con 8 canales&#46; Se analizaron las siguientes variables&#58; sexo&#44; motivo de consulta&#44; procedencia&#44; exploraci&#243;n de la v&#237;a a&#233;rea superior&#44; edad&#44; z-<span class="elsevierStyleItalic">score</span> del peso &#40;cu&#225;nto se desv&#237;a la media de peso y en qu&#233; direcci&#243;n respecto de la media de peso de una distribuci&#243;n normal&#41;&#44; z-<span class="elsevierStyleItalic">score</span> de la talla &#40;cu&#225;nto se desv&#237;a la media de la talla y en qu&#233; direcci&#243;n respecto de la media de la talla de una distribuci&#243;n normal&#41;&#44; z-<span class="elsevierStyleItalic">score</span> del &#237;ndice de masa corporal &#40;IMC&#59; cu&#225;nto se desv&#237;a la media del IMC y en qu&#233; direcci&#243;n respecto de la media del IMC de una distribuci&#243;n normal&#41;&#44; n&#250;mero de apneas&#44; n&#250;mero de hipopneas&#44; &#237;ndice de apneas&#47;h&#44; &#237;ndice de hipopneas&#47;h &#237;ndice de apneas-hipopneas&#47;h &#40;IAH&#47;h&#41;&#44; saturaci&#243;n de ox&#237;geno por pulsioximetr&#237;a &#40;media y m&#237;nima&#41;&#44; n&#250;mero de ronquidos e &#237;ndice de ronquidos&#47;h&#46;</p> <span class="elsevierStyleSectionTitle">Resultados</span><p class="elsevierStyleSimplePara elsevierViewall">Se estudi&#243; a 400 pacientes&#44; con una edad media de 4&#44;95 a&#241;os&#44; de los que 242 eran varones &#40;60&#44;5&#37;&#41; y 158 ni&#241;as &#40;39&#44;5&#37;&#41;&#46; Se diagnostic&#243; de SAHOS &#40;IAH&#47;h &#8805; 3&#41; a 298 &#40;74&#44;5&#37;&#41;&#44; y en &#233;stos se analiz&#243; la relaci&#243;n entre SAHOS y obesidad&#46; La distribuci&#243;n antropom&#233;trica &#40;expresada en media &#177; desviaci&#243;n est&#225;ndar&#41; fue la siguiente&#58; z-peso de 0&#44;37 &#177; 1&#44;31&#59; z-talla de 0&#44;23 &#177; 1&#44;19&#59; IMC de 17&#44;063 &#177; 2&#44;51 kg&#47;m<span class="elsevierStyleSup">2</span>&#44; y z-IMC de 0&#44;39 &#177; 1&#44;36&#46; Los resultados de la poligraf&#237;a respiratoria durante el sue&#241;o mostraron un IAH&#47;h de 6&#44;56 &#177; 7&#44;56&#46;</p> <span class="elsevierStyleSectionTitle">Conclusiones</span><p class="elsevierStyleSimplePara elsevierViewall">No se han encontrado diferencias entre z-talla&#44; z-peso&#44; z-IMC&#44; edad e IAH&#47;h&#46; En esta serie la obesidad no se asocial a SAHOS&#46; Sin embargo&#44; se requieren estudios en poblaciones m&#225;s amplias y no preseleccionadas para evaluar si la obesidad act&#250;a o no como factor de riesgo para desarrollar SAHOS en ni&#241;os&#46;</p>"
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Vol. 42. Issue 11.
Pages 583-587 (November 2006)
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Vol. 42. Issue 11.
Pages 583-587 (November 2006)
Original Articles
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Obstructive Sleep Apnea-Hypopnea Syndrome in Children Is Not Associated With Obesity
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Olaia Sardóna,
Corresponding author
osardon@chdo.osakidetza.net

Correspondence: Dra. O. Sardón. Unidad de Neumología Infantil. Hospital Donostia. Avda. Dr. Beguiristain, s/n. 20014 San Sebastián. Guipúzcoa. España
, Eduardo González Pérez-Yarzaa, Ane Aldasoraa, Andrea Bordoya, Javier Minteguia, José Ignacio Emparanzab
a Unidad de Neumología, Servicio de Pediatría, Hospital Donostia, San Sebastián, Guipúzcoa, Spain
b Unidad de Epidemiología Clínica e Investigación, Hospital Donostia, San Sebastián, Guipúzcoa, Spain
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Objective

The prevalence of obstructive sleep apnea hypopnea syndrome (OSAHS) in the general pediatric population ranges from 1% to 3%. However, its prevalence in an unselected population of obesity and OSAHS in children diagnosed with the syndrome in a cohort of boys and girls (age range, 2-14 years) referred to the pediatric respiratory medicine outpatient clinic at our hospital for suspected apnea, snoring, or both over the past 5 years.

Patients and methods

The medical history of each patient was recorded and all patients underwent a physical examination, chest and nasal cavities radiography, and 8-channel respiratory polygraphy during sleep. the following variables were evaluated: sex, reason for consultation, source of referral, findings during upper airway examination, age, weight z-score (reflecting how much a finding differs from the mean and in what direction in a normally distributed sample), height z-score, body mass index (BMI) z-score, number of apneas, number of hypopneas, apnea index, hypopnea index, apnea-hypopnea index (AHI), oxygen saturation (mean and minimum) measured by pulse oximetry, number of snores, and snore index.

Results

Of the 400 patients studied, 242 (60.5%) were male and 158 (39.5%) female. the mean age was 4.95 years. OSAHS (AHI≥3) was diagnosed in 298 cases (74.5%) and these patients were then studied to determine the relation between OSAHS and obesity. the anthropometric distribution (expressed as mean [SD]) was as follows: weight z-score, 0.37 (1.31); height z-score, 0.23 (1.19); BMI, 17.063 kg/m2 (2.51); and BMI z-score, 1.39 (1.36). the respiratory polygraph during sleep recorded an AHI of 6.56 (7.56).

Conclusions

No differences were observed between the height z-score, weight z-score, BMI z-score, age, and AHI. No association between obesity and OSAHS was found in this series. However, studies of larger, unselected populations are needed to determine if obesity is a risk factor for OSAHS in children.

Key words:
Obstructive sleep apnea-hypopnea syndrome
OSAHS
Obstructive apneas
Obesity
Children
Objetivo

El síndrome de apneas-hipopneas obstructivas durante el sueño (SAHOS) alcanza una prevalencia del 1-3% en población general infantile. Sin embargo, en población obesa no preseleccionada la prevalencia es desconocida. Para estudiar la asociación entre SAHOS y obesidad en niños diagnosticados de dicho trastorno, hemos analizado a una cohorte de niños y niñas (2-14 años) remitidos en los últimos 5 años a consulta externas de neumología infantile porsospecha de apneas durante el sueño, ronquido o ambos.

Pacientes y métodos

A los pacientes incluidos se les realizaron anamesis, exploración física, radiografía de tórax y cávum y poligrafía respiratoria durante el sueño con 8 canales. Se analizaron las siguientes variables: sexo, motivo de consulta, procedencia, exploración de la vía aérea superior, edad, z-score del peso (cuánto se desvía la media de peso y en qué dirección respecto de la media de peso de una distribución normal), z-score de la talla (cuánto se desvía la media de la talla y en qué dirección respecto de la media de la talla de una distribución normal), z-score del índice de masa corporal (IMC; cuánto se desvía la media del IMC y en qué dirección respecto de la media del IMC de una distribución normal), número de apneas, número de hipopneas, índice de apneas/h, índice de hipopneas/h índice de apneas-hipopneas/h (IAH/h), saturación de oxígeno por pulsioximetría (media y mínima), número de ronquidos e índice de ronquidos/h.

Resultados

Se estudió a 400 pacientes, con una edad media de 4,95 años, de los que 242 eran varones (60,5%) y 158 niñas (39,5%). Se diagnosticó de SAHOS (IAH/h ≥ 3) a 298 (74,5%), y en éstos se analizó la relación entre SAHOS y obesidad. La distribución antropométrica (expresada en media ± desviación estándar) fue la siguiente: z-peso de 0,37 ± 1,31; z-talla de 0,23 ± 1,19; IMC de 17,063 ± 2,51 kg/m2, y z-IMC de 0,39 ± 1,36. Los resultados de la poligrafía respiratoria durante el sueño mostraron un IAH/h de 6,56 ± 7,56.

Conclusiones

No se han encontrado diferencias entre z-talla, z-peso, z-IMC, edad e IAH/h. En esta serie la obesidad no se asocial a SAHOS. Sin embargo, se requieren estudios en poblaciones más amplias y no preseleccionadas para evaluar si la obesidad actúa o no como factor de riesgo para desarrollar SAHOS en niños.

Palabras clave:
Síndrome de apneas-hipopneas durante el sueño
Apneas obstructivas
Obesidad
Niños
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