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Vol. 40. Issue 11.
Pages 534-536 (November 2004)
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Vol. 40. Issue 11.
Pages 534-536 (November 2004)
Case Reports
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Lung Scintigraphy With Technetium 99m Depreotide in the Assessment of Solitary Pulmonary Nodules
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A.C. Rebolloa, J.M. Jiménez-Hoyuelaa,
Corresponding author
jjimenezhog@commalaga.org

Correspondence: Dr. J.M. Jiménez-Hoyuela. Servicio de Medicina Nuclear. Hospital Universitario Virgen de la Victoria. Campus Universitario de Teatinos, s/n. 29010 Málaga. España
, M.D. Martínez del Vallea, C. Fernández Aguirreb, C. Soriab, J.L. Velascob
a Nuclear Medicine Department, Hospital Universitario Virgen de la Victoria, Málaga, Spain
b Pneumology Department, Hospital Universitario Virgen de la Victoria, Málaga, Spain
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A solitary pulmonary nodule (SPN) is defined as a parenchymal lesion measuring less than 3 cm in diameter that is not associated with other lesions. Ninety percent of SPNs are discovered incidentally and most are benign. The management of radiographically indeterminate SPNs has not been established and invasive procedures must be undertaken in order to understand the nature of the nodule. We review our experience with the use of somatostatin receptor scintigraphy with technetium Tc99m depreotide in 10 patients with suspected malignant SPN. We discuss the limitations and applications of this technique in the evaluation of whether SPNs are benign or malignant for the purpose of identifying patients for biopsy. For this application, this technique can be considered an alternative to positron emission tomography using fluorine-18 fluordeoxyglucose.

Key Words:
Solitary pulmonary nodule (SPN)
Technetium Tc99m depreotide
Lung scintigraphy

El nódulo pulmonar solitario (NPS) se define como una lesión parenquimatosa única, con un tamaño inferior a 3 cm de diámetro y no asociada a otras lesiones. El 90% se descu-bre de forma casual y la mayoría es de naturaleza benigna. El tratamiento de los NPS radiológicamente indeterminados no está del todo establecido, y es necesaria la realización de técnicas invasivas con el fin de conocer la naturaleza de la lesión.

Presentamos nuestra experiencia en la gammagrafía de receptores de somatostatina con 99mTc-depreótida en 10 pa-cientes con NPS sospechosos de malignidad. Discutimos las limitaciones y aplicaciones de esta técnica en la diferencia-ción de la naturaleza benigna o maligna de las lesiones para seleccionar a los pacientes candidatos a biopsia, terreno donde puede considerarse una alternativa a la tomografía por emisión de positrones con 18fluordesoxiglucosa.

Palabras clave:
Nódulo pulmonar solitario
99mTc-depreótida
Gammagrafía pulmonar
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Copyright © 2004. Sociedad Española de Neumología y Cirugía Torácica (SEPAR)
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