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Vol. 24. Issue 1.
Pages 33-36 (January - February 1988)
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Vol. 24. Issue 1.
Pages 33-36 (January - February 1988)
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Leiomioma benigno metastatizante. Estudio ultraestructural de un nuevo caso
Benign metastasic leiomyoma. Ultrastructural examination of one further case
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4351
C. Martinez Vazquez, A. Pena, A. Ocampo
Servicio de Medicina Interna, Hospital Xeral. Vigo
M.C. Campo*, N. Alfonsin*, R. Cameselle**
* Servicio de Anatomía Patológica. Hospital Xeral. Vigo
** Servicio de Cirugía General. Hospital Xeral. Vigo
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Los autores describen un nuevo caso de leiomioma benigno metastatizante, caracterizado por la presencia de nodulos pulmonares múltiples formados por tejido tumoral muscular liso con escaso o nulo crecimiento en nueve años. Analizan la confusa terminología aplicada a esta enfermedad, proponiendo, como otros autores, denominar como tal a los casos de pacientes con leiomiomas a nivel pulmonar y uterino, inclinándose ante los hallazgos ultraestructurales por el origen uterino de los mismos.

Proponen el tratamiento antiestrogénico con tamoxifeno ante la respuesta hormonal que parecen tener y el mal pronóstico apreciado en algún caso.

We report on a further case of benign metastasic meiomyoma characterized by the presence of multiple pulmonary nodes of smooth muscle tumoral tissue which showed slight or no growth over a 9 year period. The confusing terminology currently used for this condition is analyzed. As others, we propose the use of this term in patients with lung and uterus leiomyomas, the Ultrastructural findings suggesting an uterine origin. Finally antiestrogen therapy with tamoxifen is proposed considering the hormonal response that seems to be present and the poor prognosis of some cases.

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Bibliografía
[1.]
E. Martín.
Leiomyomatous lung lesions: a proposed classification.
AJR, 141 (1983), pp. 269-272
[2.]
P.J. Friedman.
Classification of leiomyomatous lung lesions.
AJR, 142 (1984), pp. 851-852
[3.]
R. Deussing.
Múltiple primäre Myome der Lunge (ThesisA).
University of Munich, (1912),
[4.]
G. Gómez Sebastián, J.A. Maestre Alcacer, L.L. Bernardo, C. León.
Leiomiomatosis pulmonar múltiple.
Arch Bronconeumol, 20 (1984), pp. 70-74
[5.]
E. Monsó, M. Sarro, R. Pujol, B. Teixidó, M. Rubio Caballero.
Leiomiomatosis pulmonar múltiple diagnosticada por fibrobroncoscopia.
Arch Bronconeumol, 22 (1986), pp. 244-245
[6.]
J.F. Silverman, S. Kay.
Múltiple pulmonary leiomyomatous hamartomas. Report of a case with ultrastructural examination.
Cancer, 38 (1976), pp. 1.119-1.204
[7.]
R.M. Becker, J. Viloria, C. Chiu.
Múltiple pulmonary leiomyomatous hamartomas in women.
J Thorac Cardiovasc Surg, 71 (1976), pp. 631-632
[8.]
H. Minasian.
Uncommon pulmonary hamartomas.
Thorax, 32 (1977), pp. 360-364
[9.]
M. Nili, B.A. Vidne, I. Avidor, R. Paz, M.J. Levy.
Múltiple pulmonary hamartomas; a case report and review of literature.
Scand J Thor Cardiovasc Surg, (1979), pp. 157-160
[10.]
A.S. Banner, C.B. Carrington, W.B. Emory, et al.
Efficacy of oophorectomy in lymphangiomyomatosis and benign metastasizing leiomyoma.
N Engl J Med, 305 (1981), pp. 204-209
[11.]
E. Pocock, J.R. Craig, W.K. Bullock.
Metastatic uterine leiomyomata. A case repon.
Cancer, 38 (1976), pp. 2.096-2.100
[12.]
D. Bachman, M. Wolff.
Pulmonary metastases from benign appearing smooth muscle tumors of the uterus.
AJR, 127 (1976), pp. 441-446
[13.]
J.P. Horstmann, G.G. Pietra, J.A. Harman, N.G. Cole, S. Grinspan.
Spontaneos regression of pulmonary leiomyomas during pregnancy.
Cancer, 39 (1977), pp. 314-321
[14.]
D.H. Clark, J.C. Weed.
Metastasizing leiomyoma: a case report.
Am J Obstet Gynecol, 127 (1977), pp. 672-673
[15.]
S.F. Cramer, J.S. Meyer, J.F. Kraner, M. Camel, M.T. Mazur.
Metastasizing leiomyoma of the uterus. S-phase fraction, estrogen receptor and ultrastructure.
Cancer, 45 (1980), pp. 932-937
[16.]
L.G. Tedeschi.
Múltiple pulmonary fibroleiomyomas.
Am J Obstet Gynecol, 138 (1980), pp. 468-470
[17.]
M. Wolff, G. Kaye.
Pulmonary metastases (with admixed epithelial elements) from smooth muscle neoplasms. Report of nine cases including three males.
Am J Surg Pathol, 3 (1979), pp. 325-342
[18.]
W.D. Tench, D. Dail, J.T. Gmelich, et al.
Benign metastasizing leiomyomas. A review of 21 cases.
Lab Invest, 38 (1978), pp. 367
[19.]
W.R. Hart, J.K. Billman.
A reassessment of uterine neoplasms originally diagnosed as leiomyosarcomas.
Cancer, 41 (1978), pp. 1.902-1.910
[20.]
A.S. Baner, C.B. Carrigton.
Oophorectomy in lymphangioleimyomatosis and benign metastasizing leiomyoma.
Reply N Engl J Med, 305 (1981), pp. 1.417
[21.]
J.A. Winter.
Oophorectomy in lymphangioleiomyomatosis and benign metastasizing leiomyoma.
N Engl J Med, 305 (1981), pp. 1.416-1.417
[22.]
J. Cuzick, R.D. Bulbrook, D.Y. Wang.
La prevención del cáncer de mama.
Lancet (ed. esp.), 8 (1986), pp. 328-331
Copyright © 1988. Sociedad Española de Neumología y Cirugía Torácica
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