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Vol. 46. Issue 5.
Pages 275-277 (May 2010)
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Vol. 46. Issue 5.
Pages 275-277 (May 2010)
Case report
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Hypersensitivity Pneumonitis after Exposure to Candida spp
Neumonitis por hipersensibilidad tras exposición a Candida spp
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Carlos Serranoa, Alfonso Torregob, Alfonso Looslic, Antonio Valeroc,
Corresponding author
valero@clinic.ub.es

Corresponding author.
, César Picadoc
a Unidad de Alergia, Hospital Fundación Valle del Lili, Cali, Colombia
b Servicio de Neumología, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain
c Servicio de Neumología y Alergia Respiratoria, Institut del Tórax, Hospital Clínic, Barcelona, Spain
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Abstract

Hypersensitivity pneumonitis (HP) is a lung disease caused by heavy and recurrent inhalation of antigens. We describe the case of a patient with HP caused by domestic exposure to Candida spp. The diagnosis was made by taking into consideration the clinical presentation, exposure history, radiological findings, bronchoalveolar lavage, lung function and the immuno-allergy study. The diagnosis was definitively confirmed by performing a specific bronchial provocation test. It has been shown that there is crossreactivity between different Candida species, and despite making the diagnosis in this case with Candida albicans, we were unable to define exactly which species was responsible for the HP.

Keywords:
Hypersensitivity pneumonitis
Candida albicans
Lung disease
Resumen

La neumonitis por hipersensibilidad (NH) es una enfermedad pulmonar debida a la exposición a diferentes antígenos por vía inhalada de forma intensa y recurrente. Describimos el caso de un paciente con NH por exposición doméstica a Candida spp. Para llegar al diagnóstico se consideraron la presentación clínica, el antecedente de exposición, los hallazgos radiológicos, el lavado broncoalveolar, la función pulmonar y el estudio inmunoalergológico, siendo confirmado de forma definitiva tras la realización de la provocación bronquial específica. Se ha demostrado reactividad cruzada entre diferentes especies de Candida y, a pesar de realizar el diagnóstico en este caso con Candida albicans, no podemos definir con exactitud qué especie es la responsable de la NH.

Palabras clave:
Neumonitis por hipersensibilidad
Candida albicans
Enfermedad pulmonar
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