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Journal Information
Vol. 33. Issue 3.
Pages 148-150 (March 1997)
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Vol. 33. Issue 3.
Pages 148-150 (March 1997)
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Hipertensión pulmonar primaria: tratamiento con prostaciclina como puente al trasplante pulmonar
Primary pulmonary hipertensión: transitional treatment with prostacyclin before lung transplantation
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3605
P. Morales1, P.J. Cordero
Servicios de Neumología, Hospital Universitario La Fe. Valencia
L. Almenar*, R. Vicente**, F. Ramos**, J.M. Borro***
* Servicios de Cardiología, Hospital Universitario La Fe. Valencia
** Servicios de Anestesia y Reanimación, Hospital Universitario La Fe. Valencia
*** Servicios de Cirugía Torácica. Hospital Universitario La Fe. Valencia
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Presentamos la experiencia obtenida en 2 pacientes diagnosticados de hipertensión pulmonar primaria y posteriormente trasplantados que recibieron tratamiento con vasodilatadores pulmonares de acción corta (epoprostenol) como puente al trasplante pulmonar. En un primer paciente, varón de 19 años, se mantuvo el tratamiento en perfusión intravenosa continua, a dosis de 6ng/kg/min durante 26 días y en una segunda paciente, mujer de 49 años, a dosis inicial de 4ng/kg/min y posteriormente de 6ng/kg/min durante 6 meses. En ambos casos se redujo drásticamente la semiología previa, mejorando significativamente su calidad de vida.

Palabras clave:
Hipertensión pulmonar
Prostaciclina
Trasplante pulmonar

We report our experience with two patients diagnosed of primary pulmonary hypertension who later received lung transplants, with treatment with short-acting pulmonary vasodilators (epoprostenol) provided as a bridge to transplantation. Continuous intravenous perfusion at a dose of 6ng/kg/min was provided to the first patient, a 19-year-old man, for 26 days. An initial dose of 4ng/kg/min followed by 6ng/kg/min was given to the second patient, a 49-year-old woman, for 6 months. Symptoms were drastically reduced in both patients, significantly improving their quality of life.

Key words:
Pulmonary hypertension
Prostacyclin
Lung transplantation
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Copyright © 1997. Sociedad Española de Neumología y Cirugía Torácica
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