Hipertensión pulmonar primaria: tratamiento con prostaciclina como puente al trasplante pulmonar
Primary pulmonary hipertensión: transitional treatment with prostacyclin before lung transplantation
Servicios de Neumología, Hospital Universitario La Fe. Valencia
Read
3606
Timeswas read the article
1549
Total PDF
2057
Total HTML
Share statistics
array:23 [ "pii" => "S0300289615306451" "issn" => "03002896" "doi" => "10.1016/S0300-2896(15)30645-1" "estado" => "S300" "fechaPublicacion" => "1997-03-01" "aid" => "70715" "copyright" => "Sociedad Española de Neumología y Cirugía Torácica" "copyrightAnyo" => "1997" "documento" => "article" "crossmark" => 0 "subdocumento" => "fla" "cita" => "Arch Bronconeumol. 1997;33:148-50" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 1321 "formatos" => array:3 [ "EPUB" => 80 "HTML" => 753 "PDF" => 488 ] ] "itemSiguiente" => array:18 [ "pii" => "S0300289615306463" "issn" => "03002896" "doi" => "10.1016/S0300-2896(15)30646-3" "estado" => "S300" "fechaPublicacion" => "1997-03-01" "aid" => "70716" "copyright" => "Sociedad Española de Neumología y Cirugía Torácica" "documento" => "article" "crossmark" => 0 "subdocumento" => "fla" "cita" => "Arch Bronconeumol. 1997;33:151-3" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 1736 "formatos" => array:3 [ "EPUB" => 83 "HTML" => 1005 "PDF" => 648 ] ] "es" => array:10 [ "idiomaDefecto" => true "titulo" => "Tratamiento conservador en dos lesiones traqueales secundarias a intubación anestésica" "tienePdf" => "es" "tieneTextoCompleto" => 0 "tieneResumen" => array:2 [ 0 => "es" 1 => "en" ] "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "151" "paginaFinal" => "153" ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Conservative treatment of two tracheal lesions secondary to intubation for anesthesia" ] ] "contieneResumen" => array:2 [ "es" => true "en" => true ] "contienePdf" => array:1 [ "es" => true ] "autores" => array:2 [ 0 => array:2 [ "autoresLista" => "L.J. Buitrago, L. Molins, G. Vidal" "autores" => array:3 [ 0 => array:2 [ "nombre" => "L.J." "apellidos" => "Buitrago" ] 1 => array:2 [ "nombre" => "L." "apellidos" => "Molins" ] 2 => array:2 [ "nombre" => "G." "apellidos" => "Vidal" ] ] ] 1 => array:2 [ "autoresLista" => "J.E. Boada, J.J. Sopeña" "autores" => array:2 [ 0 => array:2 [ "nombre" => "J.E." "apellidos" => "Boada" ] 1 => array:2 [ "nombre" => "J.J." "apellidos" => "Sopeña" ] ] ] ] ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0300289615306463?idApp=UINPBA00003Z" "url" => "/03002896/0000003300000003/v1_201506200427/S0300289615306463/v1_201506200427/es/main.assets" ] "itemAnterior" => array:18 [ "pii" => "S030028961530644X" "issn" => "03002896" "doi" => "10.1016/S0300-2896(15)30644-X" "estado" => "S300" "fechaPublicacion" => "1997-03-01" "aid" => "70714" "copyright" => "Sociedad Española de Neumología y Cirugía Torácica" "documento" => "article" "crossmark" => 0 "subdocumento" => "fla" "cita" => "Arch Bronconeumol. 1997;33:143-7" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 1777 "formatos" => array:3 [ "EPUB" => 63 "HTML" => 978 "PDF" => 736 ] ] "es" => array:7 [ "idiomaDefecto" => true "titulo" => "Trastornos respiratorios del sueño en el síndrome de fibromialgia" "tienePdf" => "es" "tieneTextoCompleto" => 0 "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "143" "paginaFinal" => "147" ] ] "contienePdf" => array:1 [ "es" => true ] "autores" => array:2 [ 0 => array:2 [ "autoresLista" => "B. Álvarez Lario" "autores" => array:1 [ 0 => array:2 [ "nombre" => "B." "apellidos" => "Álvarez Lario" ] ] ] 1 => array:2 [ "autoresLista" => "J.L. Viejo Bañuelos" "autores" => array:1 [ 0 => array:2 [ "nombre" => "J.L." "apellidos" => "Viejo Bañuelos" ] ] ] ] ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S030028961530644X?idApp=UINPBA00003Z" "url" => "/03002896/0000003300000003/v1_201506200427/S030028961530644X/v1_201506200427/es/main.assets" ] "es" => array:14 [ "idiomaDefecto" => true "titulo" => "Hipertensión pulmonar primaria: tratamiento con prostaciclina como puente al trasplante pulmonar" "tieneTextoCompleto" => 0 "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "148" "paginaFinal" => "150" ] ] "autores" => array:2 [ 0 => array:4 [ "autoresLista" => "P. Morales, P.J. Cordero" "autores" => array:2 [ 0 => array:3 [ "nombre" => "P." "apellidos" => "Morales" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">1</span>" "identificador" => "cor0005" ] ] ] 1 => array:2 [ "nombre" => "P.J." "apellidos" => "Cordero" ] ] "afiliaciones" => array:1 [ 0 => array:2 [ "entidad" => "Servicios de Neumología, Hospital Universitario La Fe. Valencia" "identificador" => "aff0005" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "1" "correspondencia" => "Correspondencia: Servicio de Neumología. Hospital Universitario La Fe. Avda. Campanar, 21. 46009 Valencia." ] ] ] 1 => array:3 [ "autoresLista" => "L. Almenar, R. Vicente, F. Ramos, J.M. Borro" "autores" => array:4 [ 0 => array:3 [ "nombre" => "L." "apellidos" => "Almenar" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">*</span>" "identificador" => "aff0010" ] ] ] 1 => array:3 [ "nombre" => "R." "apellidos" => "Vicente" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">**</span>" "identificador" => "aff0015" ] ] ] 2 => array:3 [ "nombre" => "F." "apellidos" => "Ramos" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">**</span>" "identificador" => "aff0015" ] ] ] 3 => array:3 [ "nombre" => "J.M." "apellidos" => "Borro" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">***</span>" "identificador" => "aff0020" ] ] ] ] "afiliaciones" => array:3 [ 0 => array:3 [ "entidad" => "Servicios de Cardiología, Hospital Universitario La Fe. Valencia" "etiqueta" => "*" "identificador" => "aff0010" ] 1 => array:3 [ "entidad" => "Servicios de Anestesia y Reanimación, Hospital Universitario La Fe. Valencia" "etiqueta" => "**" "identificador" => "aff0015" ] 2 => array:3 [ "entidad" => "Servicios de Cirugía Torácica. Hospital Universitario La Fe. Valencia" "etiqueta" => "***" "identificador" => "aff0020" ] ] ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Primary pulmonary hipertensión: transitional treatment with prostacyclin before lung transplantation" ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "1996-06-18" "fechaAceptado" => "1996-09-03" "PalabrasClave" => array:2 [ "es" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palabras clave" "identificador" => "xpalclavsec545610" "palabras" => array:3 [ 0 => "Hipertensión pulmonar" 1 => "Prostaciclina" 2 => "Trasplante pulmonar" ] ] ] "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Key words" "identificador" => "xpalclavsec545611" "palabras" => array:3 [ 0 => "Pulmonary hypertension" 1 => "Prostacyclin" 2 => "Lung transplantation" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "es" => array:1 [ "resumen" => "<span id="abst0005" class="elsevierStyleSection elsevierViewall"><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Presentamos la experiencia obtenida en 2 pacientes diagnosticados de hipertensión pulmonar primaria y posteriormente trasplantados que recibieron tratamiento con vasodilatadores pulmonares de acción corta (epoprostenol) como puente al trasplante pulmonar. En un primer paciente, varón de 19 años, se mantuvo el tratamiento en perfusión intravenosa continua, a dosis de 6<span class="elsevierStyleHsp" style=""></span>ng/kg/min durante 26 días y en una segunda paciente, mujer de 49 años, a dosis inicial de 4<span class="elsevierStyleHsp" style=""></span>ng/kg/min y posteriormente de 6<span class="elsevierStyleHsp" style=""></span>ng/kg/min durante 6 meses. En ambos casos se redujo drásticamente la semiología previa, mejorando significativamente su calidad de vida.</p></span>" ] "en" => array:1 [ "resumen" => "<span id="abst0010" class="elsevierStyleSection elsevierViewall"><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">We report our experience with two patients diagnosed of primary pulmonary hypertension who later received lung transplants, with treatment with short-acting pulmonary vasodilators (epoprostenol) provided as a bridge to transplantation. Continuous intravenous perfusion at a dose of 6<span class="elsevierStyleHsp" style=""></span>ng/kg/min was provided to the first patient, a 19-year-old man, for 26 days. An initial dose of 4<span class="elsevierStyleHsp" style=""></span>ng/kg/min followed by 6<span class="elsevierStyleHsp" style=""></span>ng/kg/min was given to the second patient, a 49-year-old woman, for 6 months. Symptoms were drastically reduced in both patients, significantly improving their quality of life.</p></span>" ] ] "bibliografia" => array:2 [ "titulo" => "Bibliografía" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:7 [ 0 => array:3 [ "identificador" => "bib0005" "etiqueta" => "1." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Primary pulmonary hypertension: natural history and the importance of thrombosis" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "V. Fuster" 1 => "P.M. Steele" 2 => "W.D. Edwards" 3 => "B.J. Gersh" 4 => "M.D. McGoon" 5 => "R.L. Frye" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Circulation" "fecha" => "1984" "volumen" => "70" "paginaInicial" => "580" "paginaFinal" => "587" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/6148159" "web" => "Medline" ] ] ] ] ] ] ] ] 1 => array:3 [ "identificador" => "bib0010" "etiqueta" => "2." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The effect of high doses of calciumchannel blockers on survival in primary pulmonary hypertension" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "S. Rich" 1 => "E. Kaufmann" 2 => "P.S. Levy" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1056/NEJM199207093270203" "Revista" => array:6 [ "tituloSerie" => "N Engl J Med" "fecha" => "1992" "volumen" => "327" "paginaInicial" => "76" "paginaFinal" => "81" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/1603139" "web" => "Medline" ] ] ] ] ] ] ] ] 2 => array:3 [ "identificador" => "bib0015" "etiqueta" => "3." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Primary pulmonary hypertension" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "L.J. Rubin" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "ACCP consensus statement. Chest" "fecha" => "1993" "volumen" => "104" "paginaInicial" => "236" "paginaFinal" => "250" ] ] ] ] ] ] 3 => array:3 [ "identificador" => "bib0020" "etiqueta" => "4." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Indications for and results of single, bilateral, and heart-lung transplantation for pulmonary hypertension" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "K. Bando" 1 => "J.M. Armitage" 2 => "I.L. Paradis" 3 => "R.J. Keenan" 4 => "R.L. Hardesty" 5 => "H. Konishi" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "J Thorac Cardiovasc Surg" "fecha" => "1994" "volumen" => "108" "paginaInicial" => "1.056" "paginaFinal" => "1.065" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/7983884" "web" => "Medline" ] ] ] ] ] ] ] ] 4 => array:3 [ "identificador" => "bib0025" "etiqueta" => "5." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Treatment of primary pulmonary hypertension with continuous intravenous prostacyclin (epoprostenol). Results of a randomized trial" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "L.J. Rubin" 1 => "J. Mendoza" 2 => "M. Hood" 3 => "M. McGoon" 4 => "R.J. Barst" 5 => "W.B. Williams" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Ann Intern Med" "fecha" => "1990" "volumen" => "112" "paginaInicial" => "485" "paginaFinal" => "491" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/2107780" "web" => "Medline" ] ] ] ] ] ] ] ] 5 => array:3 [ "identificador" => "bib0030" "etiqueta" => "6." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Treatment of primary pulmonary hypertension with intravenous epoprostenol (prostacyclin)" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "D.K. Jones" 1 => "T.W. Higenbottam" 2 => "J. Wallwork" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Br Heart J" "fecha" => "1987" "volumen" => "57" "paginaInicial" => "270" "paginaFinal" => "278" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/3552006" "web" => "Medline" ] ] ] ] ] ] ] ] 6 => array:3 [ "identificador" => "bib0035" "etiqueta" => "7." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Primary pulmonary hypertension (prostacyclin) with conventional terapy for primary pulmonary hypertension" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "R.J. Barst" 1 => "L.J. Rubin" 2 => "W.A. Long" 3 => "M.D. McGoon" 4 => "S. Rich" 5 => "D.B. Badesch" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1056/NEJM199602013340504" "Revista" => array:6 [ "tituloSerie" => "N Engl J Med" "fecha" => "1996" "volumen" => "334" "paginaInicial" => "296" "paginaFinal" => "301" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8532025" "web" => "Medline" ] ] ] ] ] ] ] ] ] ] ] ] ] "idiomaDefecto" => "es" "url" => "/03002896/0000003300000003/v1_201506200427/S0300289615306451/v1_201506200427/es/main.assets" "Apartado" => array:4 [ "identificador" => "9217" "tipo" => "SECCION" "es" => array:2 [ "titulo" => "Notas clínicas" "idiomaDefecto" => true ] "idiomaDefecto" => "es" ] "PDF" => "https://static.elsevier.es/multimedia/03002896/0000003300000003/v1_201506200427/S0300289615306451/v1_201506200427/es/main.pdf?idApp=UINPBA00003Z&text.app=https://archbronconeumol.org/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0300289615306451?idApp=UINPBA00003Z" ]
| Year/Month | Html | Total | |
|---|---|---|---|
| 2024 November | 4 | 3 | 7 |
| 2024 October | 42 | 20 | 62 |
| 2024 September | 29 | 10 | 39 |
| 2024 August | 58 | 47 | 105 |
| 2024 July | 56 | 25 | 81 |
| 2024 June | 48 | 28 | 76 |
| 2024 May | 43 | 28 | 71 |
| 2024 April | 41 | 14 | 55 |
| 2024 March | 55 | 25 | 80 |
| 2024 February | 41 | 34 | 75 |
| 2024 January | 0 | 3 | 3 |
| 2023 December | 0 | 1 | 1 |
| 2023 November | 0 | 1 | 1 |
| 2023 October | 0 | 3 | 3 |
| 2023 September | 0 | 1 | 1 |
| 2023 August | 0 | 1 | 1 |
| 2023 July | 0 | 1 | 1 |
| 2023 June | 0 | 3 | 3 |
| 2023 March | 7 | 6 | 13 |
| 2023 February | 25 | 21 | 46 |
| 2023 January | 35 | 34 | 69 |
| 2022 December | 32 | 25 | 57 |
| 2022 November | 40 | 21 | 61 |
| 2022 October | 34 | 28 | 62 |
| 2022 September | 22 | 15 | 37 |
| 2022 August | 34 | 32 | 66 |
| 2022 July | 22 | 43 | 65 |
| 2022 June | 21 | 25 | 46 |
| 2022 May | 39 | 26 | 65 |
| 2022 April | 28 | 26 | 54 |
| 2022 March | 29 | 31 | 60 |
| 2022 February | 37 | 21 | 58 |
| 2022 January | 29 | 26 | 55 |
| 2021 December | 17 | 28 | 45 |
| 2021 November | 20 | 34 | 54 |
| 2021 October | 15 | 27 | 42 |
| 2021 September | 18 | 31 | 49 |
| 2021 August | 15 | 23 | 38 |
| 2021 July | 10 | 21 | 31 |
| 2021 June | 19 | 27 | 46 |
| 2021 May | 26 | 25 | 51 |
| 2021 April | 44 | 56 | 100 |
| 2021 March | 38 | 19 | 57 |
| 2021 February | 24 | 10 | 34 |
| 2021 January | 18 | 12 | 30 |
| 2020 December | 15 | 15 | 30 |
| 2020 November | 17 | 15 | 32 |
| 2020 October | 11 | 5 | 16 |
| 2020 September | 7 | 4 | 11 |
| 2020 August | 33 | 9 | 42 |
| 2020 July | 16 | 14 | 30 |
| 2020 June | 19 | 9 | 28 |
| 2020 May | 19 | 9 | 28 |
| 2020 April | 24 | 6 | 30 |
| 2020 March | 17 | 21 | 38 |
| 2020 February | 24 | 22 | 46 |
| 2020 January | 35 | 19 | 54 |
| 2019 December | 29 | 17 | 46 |
| 2019 November | 12 | 10 | 22 |
| 2019 October | 15 | 12 | 27 |
| 2019 September | 10 | 19 | 29 |
| 2019 August | 9 | 4 | 13 |
| 2019 July | 25 | 17 | 42 |
| 2019 June | 27 | 7 | 34 |
| 2019 May | 37 | 29 | 66 |
| 2019 April | 39 | 14 | 53 |
| 2019 March | 17 | 10 | 27 |
| 2019 February | 11 | 8 | 19 |
| 2019 January | 11 | 9 | 20 |
| 2018 December | 16 | 15 | 31 |
| 2018 November | 28 | 11 | 39 |
| 2018 October | 41 | 9 | 50 |
| 2018 September | 24 | 5 | 29 |
| 2018 May | 14 | 1 | 15 |
| 2018 April | 5 | 2 | 7 |
| 2018 March | 10 | 6 | 16 |
| 2018 February | 6 | 5 | 11 |
| 2018 January | 5 | 9 | 14 |
| 2017 December | 14 | 14 | 28 |
| 2017 November | 6 | 9 | 15 |
| 2017 October | 8 | 13 | 21 |
| 2017 September | 6 | 5 | 11 |
| 2017 August | 9 | 16 | 25 |
| 2017 July | 3 | 6 | 9 |
| 2017 June | 12 | 18 | 30 |
| 2017 May | 10 | 7 | 17 |
| 2017 April | 6 | 22 | 28 |
| 2017 March | 6 | 9 | 15 |
| 2017 February | 6 | 16 | 22 |
| 2017 January | 5 | 7 | 12 |
| 2016 December | 8 | 7 | 15 |
| 2016 November | 13 | 9 | 22 |
| 2016 October | 20 | 16 | 36 |
| 2016 September | 14 | 11 | 25 |
| 2016 August | 9 | 5 | 14 |
| 2016 July | 18 | 8 | 26 |
| 2016 June | 16 | 7 | 23 |
| 2016 May | 17 | 5 | 22 |
| 2016 April | 8 | 0 | 8 |
| 2016 March | 8 | 0 | 8 |
| 2016 February | 20 | 0 | 20 |
| 2016 January | 16 | 7 | 23 |
| 2015 December | 24 | 16 | 40 |
| 2015 November | 24 | 7 | 31 |
| 2015 October | 6 | 1 | 7 |
| 2015 September | 1 | 0 | 1 |
| 2015 June | 1 | 0 | 1 |
Show all
