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    "titulo" => "Fibrobroncoscopia en el cáncer de pulmón: relación entre radiología, endoscopia, histología y rendimiento diagnóstico en una serie de 1.801 casos"
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        "resumen" => "<span id="abst0005" class="elsevierStyleSection elsevierViewall"><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Se ha realizado un an&#225;lisis retrospectivo de 1&#46;801 pacientes diagnosticados de neoplasia pulmonar primaria mediante fibrobroncoscopia entre 1977 y 1992&#59; el objetivo fue investigar la relaci&#243;n entre la radiograf&#237;a de t&#243;rax&#44; los hallazgos endoscopic&#243;s y la histolog&#237;a&#44; as&#237; como valorar el rendimiento diagn&#243;stico de las diversas t&#233;cnicas endosc&#243;picas empleadas&#46;</p><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Hab&#237;a 1&#46;598 tumores de localizaci&#243;n central y 203 perif&#233;ricos&#46; El tipo histol&#243;gico m&#225;s frecuente fue el carcinoma escamoso &#40;39&#37;&#41; y el patr&#243;n radiogr&#225;fico m&#225;s com&#250;n&#44; la masa pulmonar &#40;40&#37;&#41;&#46; La endoscopia mostr&#243; infiltraci&#243;n neopl&#225;sica en el 49&#37; de los casos y tumor endobronquial en el 27&#37;&#46; Los patrones radiol&#243;gicos de masa pulmonar&#44; afectaci&#243;n hiliar y atelectasia se asociaron m&#225;s frecuentemente con la presencia de infiltraci&#243;n&#44; tumor y necrosis&#44; y con los tipos histol&#243;gicos escamoso y de c&#233;lulas peque&#241;as&#59; en ellos la biopsia bronquial obtuvo el m&#225;ximo rendimiento diagn&#243;stico&#46; Por el contrario&#44; en el n&#243;dulo pulmonar solitario y en el derrame pleural predominaron la endoscopia normal&#44; con alteraciones inespec&#237;ficas o compresi&#243;n extr&#237;nseca&#44; y los tipos celulares de adenocarcinoma y carcinoma de c&#233;lulas grandes&#59; el procedimiento con mayor valor diagn&#243;stico en este grupo fue la biopsia transbronquial &#40;especialmente bajo control radiosc&#243;pico&#41;&#46;</p><p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">Se concluye que&#44; en el c&#225;ncer de pulm&#243;n&#44; la radiograf&#237;a de t&#243;rax y el aspecto endosc&#243;pico pueden sugerir el tipo histol&#243;gico m&#225;s probable y orientar la elecci&#243;n de las t&#233;cnicas diagn&#243;sticas&#46;</p></span>"
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        "resumen" => "<span id="abst0010" class="elsevierStyleSection elsevierViewall"><p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">A retrospective analysis of 1&#44;801 patients with primary pulmonary neoplasm diagnosed by fibrobronchoscopy between 1977 and 1992 was carried out in order to determine the relation between chest <span class="elsevierStyleSmallCaps">X</span>-rays and endoscopic and histological findings&#44; as well as to assess the diagnostic usefullness of the various endoscopic techniques used&#46;</p><p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">Central tumors numbered 1&#44;598 and peripheral ones 203&#46; The largest tissue classification was squamous &#40;39&#37;&#41; and the most common <span class="elsevierStyleSmallCaps">X</span>-ray finding was pulmonary mass &#40;40&#37;&#41;&#46; Endoscopy showed neoplasic infiltration in 49&#37; of the cases and endobronchial tumor in 27&#37;&#46; <span class="elsevierStyleSmallCaps">X</span>-rays showing pulmonary mass&#44; hiliar involvement and atelectasis were more often associated with infiltration&#44; tumor and necrosis and with a smallcell tissue type&#46; Bronchial biopsy gave the best diagnostic results in these cases&#46; In cases of solitary pulmonary nodule and pleural effusion&#44; on the other hand&#44; normal endoscopic results with non-specific changes or extrapulmonary involvement&#44; predominated&#44; with adenocarcinoma and non-small cell tissue types&#46; Transbronchial biopsy&#44; especially with radioscopio monitoring&#44; was most useful in these cases&#46;</p><p id="spar0030" class="elsevierStyleSimplePara elsevierViewall">We conclude that chest <span class="elsevierStyleSmallCaps">X</span>-rays and endoscopic results can be used to predict the most likely tissue type in lung cancer and that they can serve as guides for the choice of diagnostic technique&#46;</p></span>"
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                            3 => "H&#46; Nishio"
                            4 => "T&#46; Sakuma"
                            5 => "H&#46; Ikegami"
                            6 => "R&#46; Tateishi"
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                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/3024348"
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              "referencia" => array:1 [
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                            3 => "C&#46; Grubb"
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                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
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                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/2200159"
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                0 => array:2 [
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                    0 => array:2 [
                      "titulo" => "Diagnostic sensitivity of different techniques in the diagnosis of lung tumors with the flexible fiberoptic bronchoscope&#46; Comparison of brush biopsy&#44; imprint citology of forceps biopsy&#44; and histology of forceps biopsy"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
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                            3 => "S&#46; Redtenbacher"
                            4 => "H&#46; Zwick"
                            5 => "W&#46; Dutz"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
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                        "fecha" => "1991"
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                        "paginaInicial" => "72"
                        "paginaFinal" => "75"
                        "link" => array:1 [
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                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/1985726"
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                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/908215"
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                        "paginaInicial" => "123"
                        "paginaFinal" => "126"
                        "link" => array:1 [
                          0 => array:2 [
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Vol. 30. Issue 6.
Pages 291-296 (June - July 1994)
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Vol. 30. Issue 6.
Pages 291-296 (June - July 1994)
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Fibrobroncoscopia en el cáncer de pulmón: relación entre radiología, endoscopia, histología y rendimiento diagnóstico en una serie de 1.801 casos
Fibrobronchoscopy in lung cancer: associations among radiology, endoscopy, histology and diagnostic value in a series of 1,801 cases
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E. Martínez Moragón1, J. Sanchis Aldás, A. de Diego Damiá, M. Martínez Francés, E. Cases Viedma, F. Sanchis Moret
Servicio de Neumología. Hospital Universitario La Fe. Valencia
J. Aparicio Urtasun*
* Servicio de Oncología Médica. Hospital Universitario La Fe. Valencia
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Se ha realizado un análisis retrospectivo de 1.801 pacientes diagnosticados de neoplasia pulmonar primaria mediante fibrobroncoscopia entre 1977 y 1992; el objetivo fue investigar la relación entre la radiografía de tórax, los hallazgos endoscopicós y la histología, así como valorar el rendimiento diagnóstico de las diversas técnicas endoscópicas empleadas.

Había 1.598 tumores de localización central y 203 periféricos. El tipo histológico más frecuente fue el carcinoma escamoso (39%) y el patrón radiográfico más común, la masa pulmonar (40%). La endoscopia mostró infiltración neoplásica en el 49% de los casos y tumor endobronquial en el 27%. Los patrones radiológicos de masa pulmonar, afectación hiliar y atelectasia se asociaron más frecuentemente con la presencia de infiltración, tumor y necrosis, y con los tipos histológicos escamoso y de células pequeñas; en ellos la biopsia bronquial obtuvo el máximo rendimiento diagnóstico. Por el contrario, en el nódulo pulmonar solitario y en el derrame pleural predominaron la endoscopia normal, con alteraciones inespecíficas o compresión extrínseca, y los tipos celulares de adenocarcinoma y carcinoma de células grandes; el procedimiento con mayor valor diagnóstico en este grupo fue la biopsia transbronquial (especialmente bajo control radioscópico).

Se concluye que, en el cáncer de pulmón, la radiografía de tórax y el aspecto endoscópico pueden sugerir el tipo histológico más probable y orientar la elección de las técnicas diagnósticas.

A retrospective analysis of 1,801 patients with primary pulmonary neoplasm diagnosed by fibrobronchoscopy between 1977 and 1992 was carried out in order to determine the relation between chest X-rays and endoscopic and histological findings, as well as to assess the diagnostic usefullness of the various endoscopic techniques used.

Central tumors numbered 1,598 and peripheral ones 203. The largest tissue classification was squamous (39%) and the most common X-ray finding was pulmonary mass (40%). Endoscopy showed neoplasic infiltration in 49% of the cases and endobronchial tumor in 27%. X-rays showing pulmonary mass, hiliar involvement and atelectasis were more often associated with infiltration, tumor and necrosis and with a smallcell tissue type. Bronchial biopsy gave the best diagnostic results in these cases. In cases of solitary pulmonary nodule and pleural effusion, on the other hand, normal endoscopic results with non-specific changes or extrapulmonary involvement, predominated, with adenocarcinoma and non-small cell tissue types. Transbronchial biopsy, especially with radioscopio monitoring, was most useful in these cases.

We conclude that chest X-rays and endoscopic results can be used to predict the most likely tissue type in lung cancer and that they can serve as guides for the choice of diagnostic technique.

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Bibliografía
[1.]
I. Izarzugaza Lizarraga.
El cáncer de pulmón en España. Revisión epidemiológica.
Arch Bronconeumol, 28 (1992), pp. 311-319
[2.]
R.H. Richardson, D.C. Zavala, P.K. Mukerjee, G.N. Bedell.
The use of fiberoptic bronchoscopy and brush biopsy in the diagnosis of suspected pulmonary malignancy.
Am Rev Respir Dis, 109 (1974), pp. 63-66
[3.]
D.A. Solomon, N.H. Solliday, D.R. Gracey.
Cytology in fiberoptic bronchoscopy. Comparison of bronchial brushing, washing and post-bronchoscopy sputum.
Chest, 65 (1974), pp. 616-619
[4.]
D.C. Zavala.
Diagnostic fiberoptic bronchoscopy: techniques and results of biopsy in 600 patients.
Chest, 68 (1975), pp. 12-19
[5.]
P.A. Kvale, F.R. Bode, S. Kini.
Diagnostic accuracy in lung cancer. Comparison of techniques used in association with flexible fiberoptic bronchoscopy.
Chest, 69 (1976), pp. 752-757
[6.]
C. Puzo, J. Castella, D. Nauffal, J. Tarrés, J. Sauret, J.M. Rodríguez Arias.
Carcinoma de pulmón. Diagnóstico broncoscópico.
Med Clin (Barc), 71 (1978), pp. 86-88
[7.]
J.R.W. Lyall, G.D. Summers, I.M. O’Brien, N.T. Bateman, C.P. Pike, M.V. Braimbridge.
Sequential brush biopsy and conventional biopsy: direct comparison of diagnostic sensitivity in lung malignancy.
Thorax, 35 (1980), pp. 929-931
[8.]
M. Matsuda, T. Horay, S. Nakamura, H. Nishio, T. Sakuma, H. Ikegami, R. Tateishi.
Bronchial brushing and bronchial biopsy: comparison of diagnostic accuracy and cell typing reliability in lung cancer.
Thorax, 41 (1986), pp. 475-478
[9.]
W.H.F. Mak, I.D.A. Johnston, M.R. Hetzel, C. Grubb.
Value of washings and brushings at fibreoptic bronchoscopy in the diagnosis of lung cancer.
Thorax, 45 (1990), pp. 373-376
[10.]
W. Popp, H. Rauscher, L. Ritschka, S. Redtenbacher, H. Zwick, W. Dutz.
Diagnostic sensitivity of different techniques in the diagnosis of lung tumors with the flexible fiberoptic bronchoscope. Comparison of brush biopsy, imprint citology of forceps biopsy, and histology of forceps biopsy.
Cancer, 67 (1991), pp. 72-75
[11.]
J.T. Stringfield, D.J. Markowitz, R.R. Bentz, M.H. Welch, J.G. Weg.
The effect of tumor size and location on diagnosis by fiberoptic bronchoscopy.
Chest, 72 (1977), pp. 474-476
[12.]
B.M. Zisholtz, H. Eisenberg.
Lung cancer cell type as a determinant of bronchoscopy yield.
Chest, 84 (1983), pp. 428-430
[13.]
G. Buccheri, P. Barberis, M.S. Delftno.
Diagnostic, morphologic and histopathologic correlates in bronchogenic carcinoma. A review of 1.045 bronchoscopic examinations.
Chest, 99 (1991), pp. 809-814
[14.]
S. Ikeda.
Atlas of flexible bronchofiberscopy.
University Park Press, (1974),
[15.]
World Health Organization.
Histological typing of tumor (2.a ed.).
Am J Clin Pathol, 77 (1982), pp. 123-126
[16.]
S. Lyubsky, M.J. Jacobson.
Lung cancer. Making the diagnosis.
Chest, 100 (1991), pp. 511-520
[17.]
M.T. Chuang, A. Marchevsky, A.S. Teirstein, P.A. Kirschner, J. Kleinerman.
Diagnosis of lung cancer by fibreoptic bronchoscopy: problems in the histological classification on non-small cell carcinomas.
Thorax, 39 (1984), pp. 175-178
[18.]
R.M. Rudd, A.R. Gellert, D.A.R. Boldy, P.R. Studdy, M.C. Pearson, D.M. Geddes, G. Sinha.
Bronchoscopic and percutaneous aspiration biopsy in the diagnosis of bronchial carcinoma cell type.
Thorax, 37 (1982), pp. 462-465
[19.]
J. Castella, M.C. Puzo.
Broncología.
Salvat Editores S.A, (1982),
[20.]
A.C. Arroliga, R.A. Matthay.
The role of bronchoscopy in lung cancer.
Clin Chest Med, 14 (1993), pp. 87-98
[21.]
M. Pirozynski.
Bronchoalveolar lavage in the diagnosis of peripheral, primary lung cancer.
Chest, 102 (1992), pp. 372-374
[22.]
A. De Diego, L. Compte, J. Sanchis, M.J. Enguidanos, V. Marco.
Usefulness of carcinoembryonic antigen determination in bronchoalveolar lavage fluid.
Chest, 100 (1991), pp. 1.060-1.063
Copyright © 1994. Sociedad Española de Neumología y Cirugía Torácica
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