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    "titulo" => "Fibrobroncoscopia en el cáncer de pulmón: relación entre radiología, endoscopia, histología y rendimiento diagnóstico en una serie de 1.801 casos"
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        "resumen" => "<span id="abst0005" class="elsevierStyleSection elsevierViewall"><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Se ha realizado un an&#225;lisis retrospectivo de 1&#46;801 pacientes diagnosticados de neoplasia pulmonar primaria mediante fibrobroncoscopia entre 1977 y 1992&#59; el objetivo fue investigar la relaci&#243;n entre la radiograf&#237;a de t&#243;rax&#44; los hallazgos endoscopic&#243;s y la histolog&#237;a&#44; as&#237; como valorar el rendimiento diagn&#243;stico de las diversas t&#233;cnicas endosc&#243;picas empleadas&#46;</p><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Hab&#237;a 1&#46;598 tumores de localizaci&#243;n central y 203 perif&#233;ricos&#46; El tipo histol&#243;gico m&#225;s frecuente fue el carcinoma escamoso &#40;39&#37;&#41; y el patr&#243;n radiogr&#225;fico m&#225;s com&#250;n&#44; la masa pulmonar &#40;40&#37;&#41;&#46; La endoscopia mostr&#243; infiltraci&#243;n neopl&#225;sica en el 49&#37; de los casos y tumor endobronquial en el 27&#37;&#46; Los patrones radiol&#243;gicos de masa pulmonar&#44; afectaci&#243;n hiliar y atelectasia se asociaron m&#225;s frecuentemente con la presencia de infiltraci&#243;n&#44; tumor y necrosis&#44; y con los tipos histol&#243;gicos escamoso y de c&#233;lulas peque&#241;as&#59; en ellos la biopsia bronquial obtuvo el m&#225;ximo rendimiento diagn&#243;stico&#46; Por el contrario&#44; en el n&#243;dulo pulmonar solitario y en el derrame pleural predominaron la endoscopia normal&#44; con alteraciones inespec&#237;ficas o compresi&#243;n extr&#237;nseca&#44; y los tipos celulares de adenocarcinoma y carcinoma de c&#233;lulas grandes&#59; el procedimiento con mayor valor diagn&#243;stico en este grupo fue la biopsia transbronquial &#40;especialmente bajo control radiosc&#243;pico&#41;&#46;</p><p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">Se concluye que&#44; en el c&#225;ncer de pulm&#243;n&#44; la radiograf&#237;a de t&#243;rax y el aspecto endosc&#243;pico pueden sugerir el tipo histol&#243;gico m&#225;s probable y orientar la elecci&#243;n de las t&#233;cnicas diagn&#243;sticas&#46;</p></span>"
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        "resumen" => "<span id="abst0010" class="elsevierStyleSection elsevierViewall"><p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">A retrospective analysis of 1&#44;801 patients with primary pulmonary neoplasm diagnosed by fibrobronchoscopy between 1977 and 1992 was carried out in order to determine the relation between chest <span class="elsevierStyleSmallCaps">X</span>-rays and endoscopic and histological findings&#44; as well as to assess the diagnostic usefullness of the various endoscopic techniques used&#46;</p><p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">Central tumors numbered 1&#44;598 and peripheral ones 203&#46; The largest tissue classification was squamous &#40;39&#37;&#41; and the most common <span class="elsevierStyleSmallCaps">X</span>-ray finding was pulmonary mass &#40;40&#37;&#41;&#46; Endoscopy showed neoplasic infiltration in 49&#37; of the cases and endobronchial tumor in 27&#37;&#46; <span class="elsevierStyleSmallCaps">X</span>-rays showing pulmonary mass&#44; hiliar involvement and atelectasis were more often associated with infiltration&#44; tumor and necrosis and with a smallcell tissue type&#46; Bronchial biopsy gave the best diagnostic results in these cases&#46; In cases of solitary pulmonary nodule and pleural effusion&#44; on the other hand&#44; normal endoscopic results with non-specific changes or extrapulmonary involvement&#44; predominated&#44; with adenocarcinoma and non-small cell tissue types&#46; Transbronchial biopsy&#44; especially with radioscopio monitoring&#44; was most useful in these cases&#46;</p><p id="spar0030" class="elsevierStyleSimplePara elsevierViewall">We conclude that chest <span class="elsevierStyleSmallCaps">X</span>-rays and endoscopic results can be used to predict the most likely tissue type in lung cancer and that they can serve as guides for the choice of diagnostic technique&#46;</p></span>"
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Fibrobroncoscopia en el cáncer de pulmón: relación entre radiología, endoscopia, histología y rendimiento diagnóstico en una serie de 1.801 casos
Fibrobronchoscopy in lung cancer: associations among radiology, endoscopy, histology and diagnostic value in a series of 1,801 cases
E. Martínez Moragón1, J. Sanchis Aldás, A. de Diego Damiá, M. Martínez Francés, E. Cases Viedma, F. Sanchis Moret
Servicio de Neumología. Hospital Universitario La Fe. Valencia
J. Aparicio Urtasun*
* Servicio de Oncología Médica. Hospital Universitario La Fe. Valencia
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    "titulo" => "Fibrobroncoscopia en el c&#225;ncer de pulm&#243;n&#58; relaci&#243;n entre radiolog&#237;a&#44; endoscopia&#44; histolog&#237;a y rendimiento diagn&#243;stico en una serie de 1&#46;801 casos"
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        "titulo" => "Fibrobronchoscopy in lung cancer&#58; associations among radiology&#44; endoscopy&#44; histology and diagnostic value in a series of 1&#44;801 cases"
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        "resumen" => "<span id="abst0005" class="elsevierStyleSection elsevierViewall"><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Se ha realizado un an&#225;lisis retrospectivo de 1&#46;801 pacientes diagnosticados de neoplasia pulmonar primaria mediante fibrobroncoscopia entre 1977 y 1992&#59; el objetivo fue investigar la relaci&#243;n entre la radiograf&#237;a de t&#243;rax&#44; los hallazgos endoscopic&#243;s y la histolog&#237;a&#44; as&#237; como valorar el rendimiento diagn&#243;stico de las diversas t&#233;cnicas endosc&#243;picas empleadas&#46;</p><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Hab&#237;a 1&#46;598 tumores de localizaci&#243;n central y 203 perif&#233;ricos&#46; El tipo histol&#243;gico m&#225;s frecuente fue el carcinoma escamoso &#40;39&#37;&#41; y el patr&#243;n radiogr&#225;fico m&#225;s com&#250;n&#44; la masa pulmonar &#40;40&#37;&#41;&#46; La endoscopia mostr&#243; infiltraci&#243;n neopl&#225;sica en el 49&#37; de los casos y tumor endobronquial en el 27&#37;&#46; Los patrones radiol&#243;gicos de masa pulmonar&#44; afectaci&#243;n hiliar y atelectasia se asociaron m&#225;s frecuentemente con la presencia de infiltraci&#243;n&#44; tumor y necrosis&#44; y con los tipos histol&#243;gicos escamoso y de c&#233;lulas peque&#241;as&#59; en ellos la biopsia bronquial obtuvo el m&#225;ximo rendimiento diagn&#243;stico&#46; Por el contrario&#44; en el n&#243;dulo pulmonar solitario y en el derrame pleural predominaron la endoscopia normal&#44; con alteraciones inespec&#237;ficas o compresi&#243;n extr&#237;nseca&#44; y los tipos celulares de adenocarcinoma y carcinoma de c&#233;lulas grandes&#59; el procedimiento con mayor valor diagn&#243;stico en este grupo fue la biopsia transbronquial &#40;especialmente bajo control radiosc&#243;pico&#41;&#46;</p><p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">Se concluye que&#44; en el c&#225;ncer de pulm&#243;n&#44; la radiograf&#237;a de t&#243;rax y el aspecto endosc&#243;pico pueden sugerir el tipo histol&#243;gico m&#225;s probable y orientar la elecci&#243;n de las t&#233;cnicas diagn&#243;sticas&#46;</p></span>"
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        "resumen" => "<span id="abst0010" class="elsevierStyleSection elsevierViewall"><p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">A retrospective analysis of 1&#44;801 patients with primary pulmonary neoplasm diagnosed by fibrobronchoscopy between 1977 and 1992 was carried out in order to determine the relation between chest <span class="elsevierStyleSmallCaps">X</span>-rays and endoscopic and histological findings&#44; as well as to assess the diagnostic usefullness of the various endoscopic techniques used&#46;</p><p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">Central tumors numbered 1&#44;598 and peripheral ones 203&#46; The largest tissue classification was squamous &#40;39&#37;&#41; and the most common <span class="elsevierStyleSmallCaps">X</span>-ray finding was pulmonary mass &#40;40&#37;&#41;&#46; Endoscopy showed neoplasic infiltration in 49&#37; of the cases and endobronchial tumor in 27&#37;&#46; <span class="elsevierStyleSmallCaps">X</span>-rays showing pulmonary mass&#44; hiliar involvement and atelectasis were more often associated with infiltration&#44; tumor and necrosis and with a smallcell tissue type&#46; Bronchial biopsy gave the best diagnostic results in these cases&#46; In cases of solitary pulmonary nodule and pleural effusion&#44; on the other hand&#44; normal endoscopic results with non-specific changes or extrapulmonary involvement&#44; predominated&#44; with adenocarcinoma and non-small cell tissue types&#46; Transbronchial biopsy&#44; especially with radioscopio monitoring&#44; was most useful in these cases&#46;</p><p id="spar0030" class="elsevierStyleSimplePara elsevierViewall">We conclude that chest <span class="elsevierStyleSmallCaps">X</span>-rays and endoscopic results can be used to predict the most likely tissue type in lung cancer and that they can serve as guides for the choice of diagnostic technique&#46;</p></span>"
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ISSN: 03002896
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