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array:23 [ "pii" => "S1579212921000926" "issn" => "15792129" "doi" => "10.1016/j.arbr.2020.07.024" "estado" => "S300" "fechaPublicacion" => "2021-04-01" "aid" => "2604" "copyright" => "SEPAR" "copyrightAnyo" => "2020" "documento" => "article" "crossmark" => 1 "subdocumento" => "sco" "cita" => "Arch Bronconeumol. 2021;57:302" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:1 [ "total" => 0 ] "itemSiguiente" => array:18 [ "pii" => "S157921292100094X" "issn" => "15792129" "doi" => "10.1016/j.arbr.2020.08.016" "estado" => "S300" "fechaPublicacion" => "2021-04-01" "aid" => "2611" "copyright" => "SEPAR" "documento" => "article" "crossmark" => 1 "subdocumento" => "sco" "cita" => "Arch Bronconeumol. 2021;57:303" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:1 [ "total" => 0 ] "en" => array:11 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Clinical Image</span>" "titulo" => "Black Bronchoscopy in the Diagnosis of a Lung Mass" "tienePdf" => "en" "tieneTextoCompleto" => "en" "paginas" => array:1 [ 0 => array:1 [ "paginaInicial" => "303" ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Broncoscopia negra en el diagnóstico de una masa pulmonar" ] ] "contieneTextoCompleto" => array:1 [ "en" => true ] "contienePdf" => array:1 [ "en" => true ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:7 [ "identificador" => "fig0005" "etiqueta" => "Fig. 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 755 "Ancho" => 925 "Tamanyo" => 95912 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall"><span class="elsevierStyleBold">A</span>: Chest computed tomography showed right upper lobe mass with 9<span class="elsevierStyleHsp" style=""></span>cm<span class="elsevierStyleHsp" style=""></span>×<span class="elsevierStyleHsp" style=""></span>12<span class="elsevierStyleHsp" style=""></span>cm, with invasion of RULB and the right pulmonary artery. <span class="elsevierStyleBold">B</span>: Bronchoscopic examination revealed black pigmented endobronchial lesion, leading to partial occlusion of the RULB. <span class="elsevierStyleBold">C</span>: Immunohistochemical analysis showed Melan-A and HMB45 expression in tumor cells.</p>" ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "Mariana Conceição, Ângela Dias Cunha, António Reis" "autores" => array:3 [ 0 => array:2 [ "nombre" => "Mariana" "apellidos" => "Conceição" ] 1 => array:2 [ "nombre" => "Ângela Dias" "apellidos" => "Cunha" ] 2 => array:2 [ "nombre" => "António" "apellidos" => "Reis" ] ] ] ] ] "idiomaDefecto" => "en" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S157921292100094X?idApp=UINPBA00003Z" "url" => "/15792129/0000005700000004/v1_202104020819/S157921292100094X/v1_202104020819/en/main.assets" ] "itemAnterior" => array:19 [ "pii" => "S1579212921000379" "issn" => "15792129" "doi" => "10.1016/j.arbr.2020.07.020" "estado" => "S300" "fechaPublicacion" => "2021-04-01" "aid" => "2555" "copyright" => "SEPAR" "documento" => "article" "crossmark" => 1 "subdocumento" => "sco" "cita" => "Arch Bronconeumol. 2021;57:301" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:1 [ "total" => 0 ] "en" => array:11 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Clinical Image</span>" "titulo" => "Radiological changes due to atypical aneurysms of the subclavian artery" "tienePdf" => "en" "tieneTextoCompleto" => "en" "paginas" => array:1 [ 0 => array:1 [ "paginaInicial" => "301" ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Alteración radiológica secundario a aneurismas aberrantes de arteria subclavia" ] ] "contieneTextoCompleto" => array:1 [ "en" => true ] "contienePdf" => array:1 [ "en" => true ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:8 [ "identificador" => "fig0005" "etiqueta" => "Fig. 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 1445 "Ancho" => 1500 "Tamanyo" => 167745 ] ] "detalles" => array:1 [ 0 => array:3 [ "identificador" => "at0005" "detalle" => "Fig. " "rol" => "short" ] ] "descripcion" => array:1 [ "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">(A) PA and lateral chest X-ray showing mediastinal widening with images significant for masses. (B) Chest CT with intravenous contrast, showing an aberrant right subclavian artery that originates in the aortic arch distal to the left subclavian artery, running behind the esophagus towards the right side, with a large, partially thrombosed aneurysm. (C) Partially thrombosed aneurysm of the descending aorta.</p>" ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "Juan Diego Alvarez Mavarez, Margarita Gutierrez Rodriguez" "autores" => array:2 [ 0 => array:2 [ "nombre" => "Juan Diego" "apellidos" => "Alvarez Mavarez" ] 1 => array:2 [ "nombre" => "Margarita" "apellidos" => "Gutierrez Rodriguez" ] ] ] ] ] "idiomaDefecto" => "en" "Traduccion" => array:1 [ "es" => array:9 [ "pii" => "S0300289620302283" "doi" => "10.1016/j.arbres.2020.07.004" "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:1 [ "total" => 0 ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0300289620302283?idApp=UINPBA00003Z" ] ] "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1579212921000379?idApp=UINPBA00003Z" "url" => "/15792129/0000005700000004/v1_202104020819/S1579212921000379/v1_202104020819/en/main.assets" ] "en" => array:15 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Clinical Image</span>" "titulo" => "The Sandwich Sign in Pleural Lymphoma" "tieneTextoCompleto" => true "paginas" => array:1 [ 0 => array:1 [ "paginaInicial" => "302" ] ] "autores" => array:1 [ 0 => array:4 [ "autoresLista" => "Maged Hassan, Lindsey Taylor, Cyrus Daneshvar" "autores" => array:3 [ 0 => array:4 [ "nombre" => "Maged" "apellidos" => "Hassan" "email" => array:1 [ 0 => "magedhmf@gmail.com" ] "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">*</span>" "identificador" => "cor0005" ] ] ] 1 => array:2 [ "nombre" => "Lindsey" "apellidos" => "Taylor" ] 2 => array:2 [ "nombre" => "Cyrus" "apellidos" => "Daneshvar" ] ] "afiliaciones" => array:1 [ 0 => array:2 [ "entidad" => "University Hospitals Plymouth National Health Service Trust, Plymouth, UK" "identificador" => "aff0005" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "⁎" "correspondencia" => "Corresponding author." ] ] ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "El signo sándwich en el linfoma pleural" ] ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:7 [ "identificador" => "fig0005" "etiqueta" => "Figure 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 844 "Ancho" => 1740 "Tamanyo" => 227605 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">(A) Axial computed tomography (CT) image shows bilateral pleural effusion and parietal pleural thickening exhibiting the sandwich sign on the left side (arrow). (B) Immunohistochemistry showing lymphoid cell highlighted by BCL2 marker.</p>" ] ] ] "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">A 74 year-old male patient was referred to the Pleural Service by the Haematology team with progressive breathlessness. The patient had been diagnosed with follicular lymphoma two years earlier with excellent clinical response to chemotherapy. A computed tomography (CT) scan with intravenous contrast showed bilateral pleural effusions in addition to the pleural sandwich sign – parietal pleural thickening with evidence of engulfment of the intercostal arteries into the pleural thickening (when the enhancing intercostal vessels (the filling) are engulfed by intra and extra-pleural lymphoid infiltration (the buns) (arrow, <a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>). The ultrasound appearance is shown in the supplementary video. On thoracentesis the fluid was chylous with pleural fluid triglyceride level of 200<span class="elsevierStyleHsp" style=""></span>mg/dL and cholesterol of 70<span class="elsevierStyleHsp" style=""></span>mg/dL. An omental biopsy showed infiltration by large lymphoid cells that were highlighted by the markers CD79a and BCL6 on immunohistochemistry (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>, panel B) thus confirming recurrence of follicular lymphoma. The patient was restarted on chemotherapy.</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><p id="par0010" class="elsevierStylePara elsevierViewall">The sandwich sign was first coined to describe the CT appearance of bulky mesenteric adenopathy that engulf from both sides mesenteric vasculature and fat, in lymphoma.<a class="elsevierStyleCrossRef" href="#bib0015"><span class="elsevierStyleSup">1</span></a> The pleural sandwich sign is reported in pleural involvement in non-Hodgkin's lymphoma and represents engulfment of intercostal vessels within lymphoid tissue, that spreads in the parietal pleural as well as the extrapleural space.<a class="elsevierStyleCrossRef" href="#bib0020"><span class="elsevierStyleSup">2</span></a> This is demonstrable on the CT scans of the presented case. Whether this is a truly pathognomonic sign for lymphomatous pleural disease is yet to be determined.</p><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0005">Author Contribution</span><p id="par0015" class="elsevierStylePara elsevierViewall">All authors were involved in the management of the patient. MH collected the report images and drafted the manuscript. All authors critically revised the manuscript and approved the final version.</p></span><span id="sec0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0010">Disclosure</span><p id="par0020" class="elsevierStylePara elsevierViewall">No conflict of interest. Written consent provided by the patient subject of the case report. The authors would like to thank Dr Rasika Singh who kindly provided the images of the pathology slides.</p></span></span>" "textoCompletoSecciones" => array:1 [ "secciones" => array:3 [ 0 => array:2 [ "identificador" => "sec0005" "titulo" => "Author Contribution" ] 1 => array:2 [ "identificador" => "sec0010" "titulo" => "Disclosure" ] 2 => array:1 [ "titulo" => "References" ] ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "apendice" => array:1 [ 0 => array:1 [ "seccion" => array:1 [ 0 => array:4 [ "apendice" => "<p id="par0030" class="elsevierStylePara elsevierViewall">The following are the supplementary data to this article:<elsevierMultimedia ident="upi0005"></elsevierMultimedia></p>" "etiqueta" => "Appendix A" "titulo" => "Supplementary Data" "identificador" => "sec0020" ] ] ] ] "multimedia" => array:2 [ 0 => array:7 [ "identificador" => "fig0005" "etiqueta" => "Figure 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 844 "Ancho" => 1740 "Tamanyo" => 227605 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">(A) Axial computed tomography (CT) image shows bilateral pleural effusion and parietal pleural thickening exhibiting the sandwich sign on the left side (arrow). (B) Immunohistochemistry showing lymphoid cell highlighted by BCL2 marker.</p>" ] ] 1 => array:5 [ "identificador" => "upi0005" "tipo" => "MULTIMEDIAECOMPONENTE" "mostrarFloat" => false "mostrarDisplay" => true "Ecomponente" => array:3 [ "fichero" => "mmc1.mp4" "ficheroTamanyo" => 854701 "Video" => array:2 [ "flv" => array:5 [ "fichero" => "mmc1.flv" "poster" => "mmc1.jpg" "tiempo" => 0 "alto" => 0 "ancho" => 0 ] "mp4" => array:5 [ "fichero" => "mmc1.m4v" "poster" => "mmc1.jpg" "tiempo" => 0 "alto" => 0 "ancho" => 0 ] ] ] ] ] "bibliografia" => array:2 [ "titulo" => "References" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0015" "bibliografiaReferencia" => array:2 [ 0 => array:3 [ "identificador" => "bib0015" "etiqueta" => "1" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The sandwich sign" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "S.M. Hardy" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1148/radiol.2263020109" "Revista" => array:5 [ "tituloSerie" => "Radiology" "fecha" => "2003" "volumen" => "226" "paginaInicial" => "651" "paginaFinal" => "652" ] ] ] ] ] ] 1 => array:3 [ "identificador" => "bib0020" "etiqueta" => "2" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The pleural sandwich sign in two cases of primary pleural lymphoma" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "Y. Kim" 1 => "M. Lee" 2 => "Y.J. Ryu" 3 => "M.-S. Cho" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.3348/kjr. 2015.16.1.213" "Revista" => array:5 [ "tituloSerie" => "Korean J Radiol" "fecha" => "2015" "volumen" => "16" "paginaInicial" => "213" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/25598693" "web" => "Medline" ] ] ] ] ] ] ] ] ] ] ] ] ] "idiomaDefecto" => "en" "url" => "/15792129/0000005700000004/v1_202104020819/S1579212921000926/v1_202104020819/en/main.assets" "Apartado" => array:4 [ "identificador" => "60604" "tipo" => "SECCION" "en" => array:2 [ "titulo" => "Clinical Images" "idiomaDefecto" => true ] "idiomaDefecto" => "en" ] "PDF" => "https://static.elsevier.es/multimedia/15792129/0000005700000004/v1_202104020819/S1579212921000926/v1_202104020819/en/main.pdf?idApp=UINPBA00003Z&text.app=https://archbronconeumol.org/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1579212921000926?idApp=UINPBA00003Z" ]
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