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Se observan además masas necróticas de predominio en hemitórax derecho, en contacto con bronquio del lóbulo superior derecho. C y D) Imágenes de broncoscopia: C) Estenosis traqueal con mucosa friable y protrusión de fragmentos de cartílago; D) División de bronquio lobar superior izquierdo e inferior izquierdo que muestran mucosa con áreas mamelonadas.</p>" ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "María Dolores Almenara Escribano, Agustín Colodro Ruiz, María Martín Armada" "autores" => array:3 [ 0 => array:2 [ "nombre" => "María Dolores" "apellidos" => "Almenara Escribano" ] 1 => array:2 [ "nombre" => "Agustín" "apellidos" => "Colodro Ruiz" ] 2 => array:2 [ "nombre" => "María" "apellidos" => "Martín Armada" ] ] ] ] ] "idiomaDefecto" => "es" "Traduccion" => array:1 [ "en" => array:9 [ "pii" => "S157921291830154X" "doi" => "10.1016/j.arbr.2018.05.012" "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:1 [ "total" => 0 ] "idiomaDefecto" => "en" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S157921291830154X?idApp=UINPBA00003Z" ] ] "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0300289617304428?idApp=UINPBA00003Z" "url" => "/03002896/0000005400000007/v1_201807020415/S0300289617304428/v1_201807020415/es/main.assets" ] ] "itemSiguiente" => array:19 [ "pii" => "S1579212918301472" "issn" => "15792129" "doi" => "10.1016/j.arbr.2018.05.005" "estado" => "S300" "fechaPublicacion" => "2018-07-01" "aid" => "1781" "copyright" => "SEPAR" "documento" => "simple-article" "crossmark" => 1 "subdocumento" => "crp" "cita" => "Arch Bronconeumol. 2018;54:390-1" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:2 [ "total" => 854 "formatos" => array:3 [ "EPUB" => 130 "HTML" => 449 "PDF" => 275 ] ] "en" => array:11 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Scientific Letter</span>" "titulo" => "Skeletal Muscle Metastasis: An Uncommon Finding in Lung Cancer" "tienePdf" => "en" "tieneTextoCompleto" => "en" "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "390" "paginaFinal" => "391" ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Metástasis musculoesqueléticas: hallazgo infrecuente asociado al cáncer de pulmón" ] ] "contieneTextoCompleto" => array:1 [ "en" => true ] "contienePdf" => array:1 [ "en" => true ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:7 [ "identificador" => "fig0005" "etiqueta" => "Fig. 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 1307 "Ancho" => 3000 "Tamanyo" => 397083 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">(A) Axial and coronal computed tomography: musculoskeletal metastasis on the left abdominal oblique muscle. (B) Axial T2 magnetic resonance image: musculoskeletal metastasis on flexor digitorum superficialis muscle of the hand; (B1) pre-treatment; (B2) post-treatment. (C) Chest PET-CT: musculoskeletal metastasis on the left iliopsoas muscle.</p>" ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "Blanca de Vega Sánchez, Ignacio Lobato Astiárraga, Rafael Lopez Castro, Maria Rosa López Pedreira, Carlos Disdier Vicente" "autores" => array:5 [ 0 => array:2 [ "nombre" => "Blanca" "apellidos" => "de Vega Sánchez" ] 1 => array:2 [ "nombre" => "Ignacio" "apellidos" => "Lobato Astiárraga" ] 2 => array:2 [ "nombre" => "Rafael" "apellidos" => "Lopez Castro" ] 3 => array:2 [ "nombre" => "Maria Rosa" "apellidos" => "López Pedreira" ] 4 => array:2 [ "nombre" => "Carlos Disdier" "apellidos" => "Vicente" ] ] ] ] ] "idiomaDefecto" => "en" "Traduccion" => array:1 [ "es" => array:9 [ "pii" => "S0300289617304283" "doi" => "10.1016/j.arbres.2017.11.011" "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:1 [ "total" => 0 ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0300289617304283?idApp=UINPBA00003Z" ] ] "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1579212918301472?idApp=UINPBA00003Z" "url" => "/15792129/0000005400000007/v1_201807020412/S1579212918301472/v1_201807020412/en/main.assets" ] "itemAnterior" => array:19 [ "pii" => "S1579212918301484" "issn" => "15792129" "doi" => "10.1016/j.arbr.2018.05.006" "estado" => "S300" "fechaPublicacion" => "2018-07-01" "aid" => "1784" "copyright" => "SEPAR" "documento" => "article" "crossmark" => 1 "subdocumento" => "sco" "cita" => "Arch Bronconeumol. 2018;54:388" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:2 [ "total" => 934 "formatos" => array:3 [ "EPUB" => 118 "HTML" => 585 "PDF" => 231 ] ] "en" => array:11 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Clinical Image</span>" "titulo" => "Core Needle Biopsy of an Anterior Mediastinal Thymoma: Creation of a Safe Access Route by Hydrodissection" "tienePdf" => "en" "tieneTextoCompleto" => "en" "paginas" => array:1 [ 0 => array:1 [ "paginaInicial" => "388" ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Biopsia con aguja gruesa de timoma en mediastino anterior: creación de ruta de acceso segura mediante hidrodisección" ] ] "contieneTextoCompleto" => array:1 [ "en" => true ] "contienePdf" => array:1 [ "en" => true ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:7 [ "identificador" => "fig0005" "etiqueta" => "Fig. 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 1435 "Ancho" => 1329 "Tamanyo" => 162269 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">(A) Axial chest CT image showing an anterior mediastinal mass (asterisk). The white line indicates the theoretical path of the biopsy from the anterior chest wall to the mediastinal mass, traversing the pleural surface and the left pulmonary parenchyma. (B) Axial chest CT image showing the creation of a small fluid collection (arrows) between the anterior chest wall and the mediastinal mass. (C) Axial maximum intensity projection CT image of chest showing the biopsy needle crossing the fluid collection (L) and penetrating the mediastinal mass (M).</p>" ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "Luis Gorospe Sarasúa, Nicolás Alejandro Almeida-Aróstegui, Paola Arrieta" "autores" => array:3 [ 0 => array:2 [ "nombre" => "Luis" "apellidos" => "Gorospe Sarasúa" ] 1 => array:2 [ "nombre" => "Nicolás Alejandro" "apellidos" => "Almeida-Aróstegui" ] 2 => array:2 [ "nombre" => "Paola" "apellidos" => "Arrieta" ] ] ] ] ] "idiomaDefecto" => "en" "Traduccion" => array:1 [ "es" => array:9 [ "pii" => "S0300289617304350" "doi" => "10.1016/j.arbres.2017.12.001" "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:1 [ "total" => 0 ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0300289617304350?idApp=UINPBA00003Z" ] ] "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1579212918301484?idApp=UINPBA00003Z" "url" => "/15792129/0000005400000007/v1_201807020412/S1579212918301484/v1_201807020412/en/main.assets" ] "en" => array:15 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Clinical Image</span>" "titulo" => "Necrotizing Granulomatous Inflammation With Airway Tissue Destruction" "tieneTextoCompleto" => true "paginas" => array:1 [ 0 => array:1 [ "paginaInicial" => "389" ] ] "autores" => array:1 [ 0 => array:4 [ "autoresLista" => "María Dolores Almenara Escribano, Agustín Colodro Ruiz, María Martín Armada" "autores" => array:3 [ 0 => array:4 [ "nombre" => "María Dolores" "apellidos" => "Almenara Escribano" "email" => array:1 [ 0 => "lolaales@hotmail.com" ] "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">*</span>" "identificador" => "cor0005" ] ] ] 1 => array:2 [ "nombre" => "Agustín" "apellidos" => "Colodro Ruiz" ] 2 => array:2 [ "nombre" => "María" "apellidos" => "Martín Armada" ] ] "afiliaciones" => array:1 [ 0 => array:2 [ "entidad" => "Servicio de Medicina Interna, Complejo Hospitalario Ciudad de Jaén, Jaén, Spain" "identificador" => "aff0005" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "⁎" "correspondencia" => "Corresponding author." ] ] ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Inflamación granulomatosa necrosante con destrucción de la vía aérea" ] ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:7 [ "identificador" => "fig0005" "etiqueta" => "Fig. 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 1351 "Ancho" => 1667 "Tamanyo" => 235206 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">(A and B) Chest CT showing significant concentric thickening of the tracheal wall and main bronchi, with vastly irregular tracheal and bronchial luminogram. Necrotic masses are also observed, mainly in the right hemithorax, contiguous with the bronchus of the right upper lobe. (C and D) Bronchoscopy images: (C) tracheal stenosis with friable mucosa and protrusion of fragments of cartilage; (D) division of left upper lobe and lower lobe bronchi, showing mucosa with mammilated areas.</p>" ] ] ] "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">We report the case of a 24-year-old man who was treated for pulmonary tuberculosis (histological diagnosis) at the age of 16. He subsequently presented acute mumps which improved with corticosteroids. When he was 19, he was admitted for monoarthritis of the ankle and a pulmonary nodule (“chronic necrotizing granulomatous inflammation”) with negative cultures and autoimmunity testing. During admission, he developed a clinical picture consistent with granulomatous meningoencephalitis (microbiology study negative) and response to steroids.</p><p id="par0010" class="elsevierStylePara elsevierViewall">In 2017, he was admitted for fever and respiratory symptoms, with mediastinal lymphadenopathy conglomerates visualized on the chest computed tomography (CT). Successive sputum stains/cultures for mycobacteria and fungi and autoimmune markers were negative. The patient was treated with antibiotics and the corticosteroid dose was increased. Radiological images of the chest lesions showed deterioration, with thickening of the tracheal wall and necrotic masses, predominantly in the right hemithorax<a class="elsevierStyleCrossRefs" href="#bib0015"><span class="elsevierStyleSup">1,2</span></a> (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>A and B). Bronchoscopy (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>C and D) showed extensive areas of inflammation/necrosis in the main airways, with loss of wall structure and protruding fragments of cartilage. The pathology study reported granulomas, extensive necrosis, and hyaline membranes.<a class="elsevierStyleCrossRef" href="#bib0020"><span class="elsevierStyleSup">2</span></a> Cultures for bacteria, mycobacteria, fungi, and panfungal PCR were negative.</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><p id="par0015" class="elsevierStylePara elsevierViewall">A prosthetic trachea was ruled out due to the severity of the lesions. In view of suspected granulomatous vasculitis (Wegener's granulomatosis),<a class="elsevierStyleCrossRefs" href="#bib0015"><span class="elsevierStyleSup">1,2</span></a> steroids and cyclophosphamide were administered by intravenous bolus, but progress was unfavorable and the patient died due to massive hemoptysis.</p></span>" "pdfFichero" => "main.pdf" "tienePdf" => true "NotaPie" => array:1 [ 0 => array:2 [ "etiqueta" => "☆" "nota" => "<p class="elsevierStyleNotepara" id="npar0005">Please cite this article as: Almenara Escribano MD, Colodro Ruiz A, Martín Armada M. Inflamación granulomatosa necrosante con destrucción de la vía aérea. Arch Bronconeumol. 2018;54:389.</p>" ] ] "multimedia" => array:1 [ 0 => array:7 [ "identificador" => "fig0005" "etiqueta" => "Fig. 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 1351 "Ancho" => 1667 "Tamanyo" => 235206 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">(A and B) Chest CT showing significant concentric thickening of the tracheal wall and main bronchi, with vastly irregular tracheal and bronchial luminogram. Necrotic masses are also observed, mainly in the right hemithorax, contiguous with the bronchus of the right upper lobe. (C and D) Bronchoscopy images: (C) tracheal stenosis with friable mucosa and protrusion of fragments of cartilage; (D) division of left upper lobe and lower lobe bronchi, showing mucosa with mammilated areas.</p>" ] ] ] "bibliografia" => array:2 [ "titulo" => "References" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0015" "bibliografiaReferencia" => array:2 [ 0 => array:3 [ "identificador" => "bib0015" "etiqueta" => "1" "referencia" => array:1 [ 0 => array:3 [ "comentario" => "vi. Review" "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Airway involvement in Wegener's granulomatosis" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "V.S. Polychronopoulos" 1 => "U.B. Prakash" 2 => "J.M. Golbin" 3 => "E.S. Edell" 4 => "U. Specks" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/j.rdc.2007.09.004" "Revista" => array:6 [ "tituloSerie" => "Rheum Dis Clin North Am" "fecha" => "2007" "volumen" => "33" "paginaInicial" => "755" "paginaFinal" => "775" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/18037115" "web" => "Medline" ] ] ] ] ] ] ] ] 1 => array:3 [ "identificador" => "bib0020" "etiqueta" => "2" "referencia" => array:1 [ 0 => array:1 [ "referenciaCompleta" => "King MD. Respiratory tract involvement in granulomatosis with polyangiitis and microscopic polyangiitis. Post TW, ed. UptoDate. Waltham, MA: UpToDate Inc. Available from: <a id="intr0010" class="elsevierStyleInterRef" href="http://www.uptodate.com/">http://www.uptodate.com</a> [accessed 10.10.17]." ] ] ] ] ] ] ] "agradecimientos" => array:1 [ 0 => array:4 [ "identificador" => "xack354682" "titulo" => "Acknowledgements" "texto" => "<p id="par0020" class="elsevierStylePara elsevierViewall">The authors thank the Respiratory Medicine Department of the Complejo Hospitalario Ciudad de Jaén for their collaboration in the preparation of this report, especially Dr. José Nieto Serrano.</p>" "vista" => "all" ] ] ] "idiomaDefecto" => "en" "url" => "/15792129/0000005400000007/v1_201807020412/S157921291830154X/v1_201807020412/en/main.assets" "Apartado" => array:4 [ "identificador" => "21342" "tipo" => "SECCION" "en" => array:2 [ "titulo" => "Clinical Image" "idiomaDefecto" => true ] "idiomaDefecto" => "en" ] "PDF" => "https://static.elsevier.es/multimedia/15792129/0000005400000007/v1_201807020412/S157921291830154X/v1_201807020412/en/main.pdf?idApp=UINPBA00003Z&text.app=https://archbronconeumol.org/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S157921291830154X?idApp=UINPBA00003Z" ]
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