Special Article
The EPI-SCAN Survey to Assess the Prevalence of Chronic Obstructive Pulmonary Disease in Spanish 40-to-80-Year-Olds: Protocol Summary
Estudio EPI-SCAN: resumen del protocolo de un estudio para estimar la prevalencia de EPOC en personas de 40 a 80 años en España
Julio Ancocheaa, Carlos Badiolab, Enric Duran-Tauleriac, Francisco García Ríod, Marc Miravitllese, Luis Muñozf, Víctor Sobradillog, Juan B. Sorianoh,
Corresponding author
a Hospital de La Princesa, Madrid, Spain
b GlaxoSmithKline, Madrid, Spain
c IMIM/CREAL, Barcelona, Spain
d Hospital La Paz, Madrid, Spain
e Servei de Pneumologia, Institut Clínic del Tòrax (IDIBAPS), Hospital Clínic i Provincial, Barcelona, Spain
f Hospital Reina Sofía, Córdoba, Spain
g Hospital de Cruces, Barakaldo, Vizcaya, Spain
h Fundación Caubet-CIMERA Illes Balears, CIBER de Enfermedades Respiratorias, Bunyola, Mallorca, Illes Balears, Spain
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The 1997 IBERPOC study, applying the old criteria of the European Respiratory Society, reported a COPD prevalence of 9.1% in the adult population of Spain. The Epidemiologic Study of COPD in Spain (EPI-SCAN) aims to determine the current prevalence of COPD in residents of Spain aged 40 to 80 years. Secondary objectives are, among others, to describe the current prevalence of smoking and changes in COPD prevalence relative to previous studies; to describe treatments received by patients, quality of life, and the BODE index (body mass index, obstruction of airflow, dyspnea, and exercise tolerance); and to measure inflammatory markers in blood and exhaled-breath condensate.</p> <span class="elsevierStyleSectionTitle">Patients and Methods</span><p class="elsevierStyleSimplePara elsevierViewall">EPI-SCAN is a population-based, cross-sectional epidemiologic study targeting the general population of Spain aged between 40 and 80 years. Participating centers were located in Barcelona, Burgos, Cordoba, Huesca, Madrid, Oviedo, Seville, Valencia, Vic, and Vigo. All subjects filled in an extensive questionnaire to collect social, demographic, and clinical information. Slow and forced spirometry tests before and after a bronchodilator test were also undertaken. Additionally, selected subjects performed a 6-minute walk test and answered generic and specific quality-of-life questionnaires, as well as an activities-of-daily-living questionnaire. Exhaled-breath condensate and blood samples were also collected from these subjects for measurement of inflammatory and other biomarkers.</p>" ] "es" => array:2 [ "titulo" => "Resumen" "resumen" => "<span class="elsevierStyleSectionTitle">Introducción y objetivos</span><p class="elsevierStyleSimplePara elsevierViewall">La enfermedad pulmonar obstructiva crónica (EPOC) es un trastorno que causa gran morbilidad y mortalidad en España. El estudio IBERPOC, realizado en 1997, identificó una prevalencia de EPOC en España, según el criterio antiguo de la European Respiratory Society, del 9,1% de la población adulta. El estudio EPI-SCAN (del inglés <span class="elsevierStyleItalic">The Epidemiologic Study of COPD in Spain</span>) pretende conocer la prevalencia de la EPOC en población de 40 a 80 años de edad residente en España en la actualidad y sus cambios en el último decenio. Otros objetivos secundarios que se plantean son describir la prevalencia de tabaquismo, la evolución de la prevalencia de EPOC respecto a estudios previos, el tratamiento recibido por los pacientes, la calidad de vida y el índice BODE (índice de masa corporal, obstrucción al flujo aéreo, disnea y capacidad de ejercicio), y determinar marcadores inflamatorios en sangre y en condensado exhalado.</p> <span class="elsevierStyleSectionTitle">Pacientes y método</span><p class="elsevierStyleSimplePara elsevierViewall">EPI-SCAN es un estudio epidemiológico de base poblacional, transversal, de ámbito nacional, llevado a cabo en población general de 40 a 80 años residente en España. Las áreas participantes fueron: Barcelona, Burgos, Córdoba, Huesca, Madrid, Oviedo, Sevilla, Valencia, Vic y Vigo. Todos los participantes rellenaron un cuestionario sociodemográfico y clínico extenso, y realizaron una espirometría lenta y forzada antes y después de una prueba broncodilatadora. Además, algunos participantes seleccionados efectuaron las siguientes pruebas: prueba de la marcha de 6 min, medición de la calidad de vida mediante cuestionarios específico y genérico, y de actividades de la vida diaria, recogida del condensado de aire exhalado y obtención de una muestra de sangre para medición de biomarcadores y diferentes parámetros inflamatorios.</p>" ] ] "bibliografia" => array:2 [ "titulo" => "References" "seccion" => array:1 [ 0 => array:1 [ "bibliografiaReferencia" => array:41 [ 0 => array:3 [ "identificador" => "bib1" "etiqueta" => "1." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease: GOLD executive summary" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "K.F. Rabe" 1 => "S. Hurd" 2 => "A. Anzueto" 3 => "P.J. Barnes" 4 => "S.A. Buist" 5 => "P. 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| Year/Month | Html | Total | |
|---|---|---|---|
| 2024 November | 5 | 5 | 10 |
| 2024 October | 37 | 13 | 50 |
| 2024 September | 24 | 10 | 34 |
| 2024 August | 53 | 42 | 95 |
| 2024 July | 23 | 34 | 57 |
| 2024 June | 45 | 28 | 73 |
| 2024 May | 55 | 39 | 94 |
| 2024 April | 22 | 22 | 44 |
| 2024 March | 31 | 18 | 49 |
| 2024 February | 19 | 20 | 39 |
| 2023 March | 3 | 2 | 5 |
| 2023 February | 17 | 24 | 41 |
| 2023 January | 16 | 30 | 46 |
| 2022 December | 27 | 38 | 65 |
| 2022 November | 27 | 32 | 59 |
| 2022 October | 21 | 35 | 56 |
| 2022 September | 20 | 48 | 68 |
| 2022 August | 31 | 41 | 72 |
| 2022 July | 16 | 40 | 56 |
| 2022 June | 30 | 36 | 66 |
| 2022 May | 40 | 26 | 66 |
| 2022 April | 19 | 33 | 52 |
| 2022 March | 21 | 39 | 60 |
| 2022 February | 14 | 27 | 41 |
| 2022 January | 16 | 41 | 57 |
| 2021 December | 25 | 46 | 71 |
| 2021 November | 20 | 48 | 68 |
| 2021 October | 30 | 56 | 86 |
| 2021 September | 22 | 66 | 88 |
| 2021 August | 8 | 35 | 43 |
| 2021 July | 17 | 41 | 58 |
| 2021 June | 21 | 44 | 65 |
| 2021 May | 17 | 30 | 47 |
| 2021 April | 42 | 72 | 114 |
| 2021 March | 33 | 20 | 53 |
| 2021 February | 14 | 26 | 40 |
| 2021 January | 14 | 23 | 37 |
| 2020 December | 20 | 25 | 45 |
| 2020 November | 15 | 20 | 35 |
| 2020 October | 13 | 8 | 21 |
| 2020 September | 11 | 8 | 19 |
| 2020 August | 12 | 17 | 29 |
| 2020 July | 19 | 19 | 38 |
| 2020 June | 19 | 7 | 26 |
| 2020 May | 37 | 19 | 56 |
| 2020 April | 38 | 27 | 65 |
| 2020 March | 43 | 23 | 66 |
| 2020 February | 81 | 36 | 117 |
| 2020 January | 63 | 23 | 86 |
| 2019 December | 22 | 19 | 41 |
| 2019 November | 14 | 32 | 46 |
| 2019 October | 6 | 10 | 16 |
| 2019 September | 16 | 31 | 47 |
| 2019 August | 16 | 20 | 36 |
| 2019 July | 13 | 30 | 43 |
| 2019 June | 8 | 18 | 26 |
| 2019 May | 6 | 13 | 19 |
| 2019 April | 15 | 21 | 36 |
| 2019 March | 13 | 23 | 36 |
| 2019 February | 6 | 12 | 18 |
| 2019 January | 9 | 8 | 17 |
| 2018 December | 6 | 13 | 19 |
| 2018 November | 37 | 17 | 54 |
| 2018 October | 42 | 18 | 60 |
| 2018 September | 24 | 17 | 41 |
| 2018 May | 4 | 0 | 4 |
| 2018 April | 13 | 5 | 18 |
| 2018 March | 3 | 5 | 8 |
| 2018 February | 10 | 14 | 24 |
| 2018 January | 9 | 13 | 22 |
| 2017 December | 4 | 11 | 15 |
| 2017 November | 6 | 5 | 11 |
| 2017 October | 14 | 13 | 27 |
| 2017 September | 4 | 6 | 10 |
| 2017 August | 10 | 12 | 22 |
| 2017 July | 9 | 7 | 16 |
| 2017 June | 16 | 25 | 41 |
| 2017 May | 11 | 6 | 17 |
| 2017 April | 9 | 3 | 12 |
| 2017 March | 18 | 16 | 34 |
| 2017 February | 5 | 9 | 14 |
| 2017 January | 5 | 9 | 14 |
| 2016 December | 10 | 9 | 19 |
| 2016 November | 11 | 6 | 17 |
| 2016 October | 20 | 11 | 31 |
| 2016 September | 16 | 11 | 27 |
| 2016 August | 15 | 4 | 19 |
| 2016 July | 11 | 5 | 16 |
| 2016 March | 5 | 0 | 5 |
| 2016 January | 1 | 0 | 1 |
| 2015 December | 1 | 0 | 1 |
| 2015 October | 47 | 11 | 58 |
| 2015 September | 52 | 6 | 58 |
| 2015 August | 45 | 7 | 52 |
| 2015 July | 70 | 10 | 80 |
| 2015 June | 57 | 7 | 64 |
| 2015 May | 42 | 7 | 49 |
| 2015 April | 43 | 7 | 50 |
| 2015 March | 33 | 13 | 46 |
| 2015 February | 27 | 7 | 34 |
| 2015 January | 56 | 5 | 61 |
| 2014 December | 53 | 9 | 62 |
| 2014 November | 36 | 8 | 44 |
| 2014 October | 66 | 14 | 80 |
| 2014 September | 43 | 8 | 51 |
| 2014 August | 39 | 12 | 51 |
| 2014 July | 43 | 12 | 55 |
| 2014 June | 53 | 11 | 64 |
| 2014 May | 66 | 13 | 79 |
| 2014 April | 68 | 7 | 75 |
| 2014 March | 74 | 17 | 91 |
| 2014 February | 65 | 11 | 76 |
| 2014 January | 41 | 8 | 49 |
| 2013 December | 57 | 15 | 72 |
| 2013 November | 50 | 8 | 58 |
| 2013 October | 55 | 17 | 72 |
| 2013 September | 71 | 13 | 84 |
| 2013 August | 71 | 18 | 89 |
| 2013 July | 60 | 16 | 76 |
| 2013 June | 58 | 21 | 79 |
| 2013 May | 43 | 15 | 58 |
| 2013 April | 38 | 9 | 47 |
| 2013 March | 11 | 2 | 13 |
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