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"tienePdf" => "en" "tieneTextoCompleto" => 0 "tieneResumen" => array:2 [ 0 => "en" 1 => "es" ] "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "591" "paginaFinal" => "596" ] ] "contieneResumen" => array:2 [ "en" => true "es" => true ] "contienePdf" => array:1 [ "en" => true ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "Miguel Ángel de Gregorio, Alicia Laborda, María Teresa Higuera, Fernando Lostale, Javier Gómez-Arrue, Carolina Serrano, Miguel Ángel Martínez, Américo Viloria" "autores" => array:8 [ 0 => array:2 [ "nombre" => "Miguel Ángel" "apellidos" => "de Gregorio" ] 1 => array:2 [ "nombre" => "Alicia" "apellidos" => "Laborda" ] 2 => array:2 [ "nombre" => "María Teresa" "apellidos" => "Higuera" ] 3 => array:2 [ "nombre" => "Fernando" "apellidos" => "Lostale" ] 4 => array:2 [ "nombre" => "Javier" "apellidos" => "Gómez-Arrue" ] 5 => array:2 [ "nombre" => "Carolina" "apellidos" => "Serrano" ] 6 => array:2 [ "nombre" => "Miguel Ángel" "apellidos" => "Martínez" ] 7 => array:2 [ "nombre" => "Américo" "apellidos" => "Viloria" ] ] ] ] ] "idiomaDefecto" => "en" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1579212908601123?idApp=UINPBA00003Z" "url" => "/15792129/0000004400000011/v1_201305150336/S1579212908601123/v1_201305150336/en/main.assets" ] "en" => array:15 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Original Articles</span>" "titulo" => "Rhinitis and Asthma Comorbidity in Spain: The RINAIR Study" "tieneTextoCompleto" => 0 "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "597" "paginaFinal" => "603" ] ] "autores" => array:1 [ 0 => array:4 [ "autoresLista" => "José Antonio, Castillo Vizuete, Joaquim Mullol Miret" "autores" => array:3 [ 0 => array:4 [ "nombre" => "José" "apellidos" => "Antonio" "email" => array:1 [ 0 => "11437jac@comb.es" ] "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">*</span>" "identificador" => "cor1" ] ] ] 1 => array:3 [ "nombre" => "Castillo" "apellidos" => "Vizuete" "referencia" => array:2 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff1" ] 1 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff2" ] ] ] 2 => array:3 [ "nombre" => "Joaquim Mullol" "apellidos" => "Miret" "referencia" => array:3 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff2" ] 1 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">c</span>" "identificador" => "aff3" ] 2 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">d</span>" "identificador" => "aff4" ] ] ] ] "afiliaciones" => array:4 [ 0 => array:3 [ "entidad" => "Servei d'Al·lèrgia i Pneumologia, Institut Universitari Dexeus, Barcelona, Spain" "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff1" ] 1 => array:3 [ "entidad" => "Grupo de Trabajo de Rinitis, Área de Asma, SEPAR" "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff2" ] 2 => array:3 [ "entidad" => "Unitat de Rinologia, Servei d'ORL, Hospital Clínic, IDIBAPS, Barcelona, Spain" "etiqueta" => "<span class="elsevierStyleSup">c</span>" "identificador" => "aff3" ] 3 => array:3 [ "entidad" => "Centro de Investigación Biomédica en Red (CibeRes) de Enfermedades Respiratorias, Barcelona, Spain" "etiqueta" => "<span class="elsevierStyleSup">d</span>" "identificador" => "aff4" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor1" "etiqueta" => "*" "correspondencia" => "Correspondence: Dr J.A. Castillo Sant Joan, 10 08870 Sitges, Barcelona, Spain" ] ] ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "2007-10-05" "fechaAceptado" => "2008-04-08" "PalabrasClave" => array:2 [ "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Key words" "identificador" => "xpalclavsec155075" "palabras" => array:6 [ 0 => "Rhinitis" 1 => "Asthma" 2 => "Comorbidity" 3 => "Lung function" 4 => "Exacerbation" 5 => "Treatment" ] ] ] "es" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palabras clave" "identificador" => "xpalclavsec155074" "palabras" => array:6 [ 0 => "Rinitis" 1 => "Asma" 2 => "Comorbilidad" 3 => "Función pulmonar" 4 => "Exacerbación" 5 => "Tratamiento" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "en" => array:1 [ "resumen" => "<span class="elsevierStyleSectionTitle">Objective</span><p class="elsevierStyleSimplePara elsevierViewall">Rhinitis and asthma share an inflammatory mechanism, epidemiological patterns, and symptoms that affect both the nose and the bronchi. The RINAIR study examined the prevalence and characteristics of rhinitis in asthma patients in Spain</p> <span class="elsevierStyleSectionTitle">Patients and methods</span><p class="elsevierStyleSimplePara elsevierViewall">This prospective epidemiological study was carried out with the participation of 15% of Spanish respiratory medicine specialists sampled randomly from different geographic areas. The study population was composed of 703 asthmatic patients aged over 16 years who were enrolled between February and September 2005. Patient characteristics, prevalence of rhinitis, lung function, allergy test results, and treatment of rhinitis were analyzed.</p> <span class="elsevierStyleSectionTitle">Results</span><p class="elsevierStyleSimplePara elsevierViewall">Seventy-one percent (n=499) of the asthmatic patients had rhinitis. These patients were younger (43.8 years vs 55.4 years; <span class="elsevierStyleItalic">P</span><.0001) and had less severe asthma (forced expiratory volume in 1 second [FEV<span class="elsevierStyleInf">1</span>], 85.7% vs 79.7% [<span class="elsevierStyleItalic">P</span><.001]) than asthmatic patients who did not have rhinitis. A correlation was observed between the severity of asthma and the severity of rhinitis (<span class="elsevierStyleItalic">P</span><.001). Atopy was significantly associated with rhinitis (odds ratio, 6.25; 95% confidence interval, 4.3-9.1): 84% of atopic patients and 51% of nonatopic patients had rhinitis. Treatment of rhinitis was associated with an increase in FEV<span class="elsevierStyleInf">1</span> (<span class="elsevierStyleItalic">P</span>=.057), irrespective of sex, age, severity of asthma, or smoking.</p> <span class="elsevierStyleSectionTitle">Conclusions</span><p class="elsevierStyleSimplePara elsevierViewall">Seventy-one percent of asthmatic patients who attended respiratory medicine clinics had rhinitis. These patients were younger and had milder asthma than asthmatics who did not have rhinitis. Furthermore, atopy was correlated with asthma associated with rhinitis. Treatment of rhinitis tended to improve lung function. These findings highlight the need to study and treat the upper and lower respiratory tract as a single airway.</p>" ] "es" => array:1 [ "resumen" => "<span class="elsevierStyleSectionTitle">Objetivo</span><p class="elsevierStyleSimplePara elsevierViewall">Rinitis y asma están ligadas por una epidemiología, clínica y mecanismo inflamatorio comunes que interrelacionan nariz y bronquio. El objetivo del estudio RINAIR ha sido estudiar la prevalencia y características de la rinitis en pacientes con asma en España.</p> <span class="elsevierStyleSectionTitle">Pacientes y métodos</span><p class="elsevierStyleSimplePara elsevierViewall">Se ha realizado un estudio epidemiológico de carácter prospectivo con la participación del 15% de los neumólogos españoles, distribuidos aleatoriamente por áreas geográficas. Se incluyó a 703 asmáticos mayores de 16 años entre febrero y septiembre de 2005. Se analizaron datos demográficos, prevalencia de rinitis, función pulmonar, pruebas alérgicas y tratamiento de la rinitis.</p> <span class="elsevierStyleSectionTitle">Resultados</span><p class="elsevierStyleSimplePara elsevierViewall">Un 71% (n = 499) de los asmáticos presentaba rinitis. Éstos eran más jóvenes (43,8 frente a 55,4 años; p < 0,0001) y presentaban un asma menos grave —volumen espiratorio forzado en el primer segundo (FEV<span class="elsevierStyleInf">1</span>): un 85,7 frente a un 79,7% (p < 0,001)— que los asmáticos sin rinitis. Se observó una correlación entre la gravedad del asma y la gravedad de la rinitis (p < 0,001). La atopia se asoció significativamente con la presencia de rinitis (<span class="elsevierStyleItalic">odds ratio</span> = 6,25; intervalo de confianza del 95%, 4,3-9,1): el 84% de los atópicos y el 51% de los no atópicos tenían rinitis. El tratamiento de la rinitis se asoció (p = 0,057) con un incremento del FEV<span class="elsevierStyleInf">1</span>, con independencia del sexo, la edad, la gravedad del asma y el hábito de fumar.</p> <span class="elsevierStyleSectionTitle">Conclusiones</span><p class="elsevierStyleSimplePara elsevierViewall">Un 71% de los asmáticos atendidos en las consultas de neumología tiene rinitis. Estos pacientes son más jóvenes y presentan un asma más leve que los asmáticos sin rinitis. Por otro lado, la atopia se relaciona con el asma asociada a rinitis. El tratamiento de la rinitis tiende a mejorar función pulmonar. Estos hallazgos indican la necesidad de estudiar y tratar toda la vía respiratoria de forma integral.</p>" ] ] "NotaPie" => array:1 [ 0 => array:1 [ "nota" => "<p class="elsevierStyleNotepara">This study was carried out within the framework of the Working Group on Rhinitis of the Assembly on Asthma of SEPAR. 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Year/Month | Html | Total | |
---|---|---|---|
2024 November | 4 | 2 | 6 |
2024 October | 32 | 19 | 51 |
2024 September | 37 | 14 | 51 |
2024 August | 55 | 34 | 89 |
2024 July | 33 | 18 | 51 |
2024 June | 49 | 38 | 87 |
2024 May | 56 | 32 | 88 |
2024 April | 21 | 21 | 42 |
2024 March | 26 | 11 | 37 |
2024 February | 25 | 24 | 49 |
2023 March | 5 | 6 | 11 |
2023 February | 24 | 19 | 43 |
2023 January | 25 | 35 | 60 |
2022 December | 26 | 29 | 55 |
2022 November | 31 | 34 | 65 |
2022 October | 26 | 32 | 58 |
2022 September | 22 | 19 | 41 |
2022 August | 22 | 40 | 62 |
2022 July | 28 | 43 | 71 |
2022 June | 21 | 41 | 62 |
2022 May | 19 | 34 | 53 |
2022 April | 25 | 31 | 56 |
2022 March | 23 | 45 | 68 |
2022 February | 17 | 27 | 44 |
2022 January | 29 | 30 | 59 |
2021 December | 19 | 56 | 75 |
2021 November | 23 | 50 | 73 |
2021 October | 33 | 62 | 95 |
2021 September | 26 | 59 | 85 |
2021 August | 10 | 30 | 40 |
2021 July | 12 | 27 | 39 |
2021 June | 13 | 25 | 38 |
2021 May | 14 | 36 | 50 |
2021 April | 58 | 60 | 118 |
2021 March | 22 | 39 | 61 |
2021 February | 15 | 21 | 36 |
2021 January | 15 | 10 | 25 |
2020 December | 12 | 24 | 36 |
2020 November | 15 | 21 | 36 |
2020 October | 23 | 19 | 42 |
2020 September | 11 | 9 | 20 |
2020 August | 10 | 14 | 24 |
2020 July | 17 | 29 | 46 |
2020 June | 11 | 11 | 22 |
2020 May | 17 | 26 | 43 |
2020 April | 20 | 29 | 49 |
2020 March | 11 | 22 | 33 |
2020 February | 21 | 25 | 46 |
2020 January | 15 | 18 | 33 |
2019 December | 14 | 27 | 41 |
2019 November | 9 | 24 | 33 |
2019 October | 15 | 12 | 27 |
2019 September | 6 | 14 | 20 |
2019 August | 22 | 15 | 37 |
2019 July | 11 | 21 | 32 |
2019 June | 6 | 12 | 18 |
2019 May | 11 | 25 | 36 |
2019 April | 43 | 37 | 80 |
2019 March | 21 | 30 | 51 |
2019 February | 14 | 20 | 34 |
2019 January | 8 | 15 | 23 |
2018 December | 6 | 23 | 29 |
2018 November | 17 | 21 | 38 |
2018 October | 22 | 15 | 37 |
2018 September | 14 | 16 | 30 |
2018 May | 1 | 0 | 1 |
2018 April | 8 | 7 | 15 |
2018 March | 3 | 3 | 6 |
2018 February | 4 | 4 | 8 |
2018 January | 2 | 5 | 7 |
2017 December | 7 | 6 | 13 |
2017 November | 4 | 16 | 20 |
2017 October | 5 | 17 | 22 |
2017 September | 5 | 15 | 20 |
2017 August | 6 | 17 | 23 |
2017 July | 2 | 18 | 20 |
2017 June | 7 | 16 | 23 |
2017 May | 3 | 7 | 10 |
2017 April | 2 | 4 | 6 |
2017 March | 4 | 11 | 15 |
2017 February | 2 | 3 | 5 |
2017 January | 4 | 5 | 9 |
2016 December | 5 | 13 | 18 |
2016 November | 9 | 11 | 20 |
2016 October | 4 | 11 | 15 |
2016 September | 10 | 13 | 23 |
2016 August | 9 | 6 | 15 |
2016 July | 8 | 6 | 14 |
2016 March | 1 | 0 | 1 |
2016 February | 2 | 0 | 2 |
2015 December | 2 | 0 | 2 |
2015 October | 44 | 7 | 51 |
2015 September | 42 | 9 | 51 |
2015 August | 41 | 7 | 48 |
2015 July | 34 | 3 | 37 |
2015 June | 41 | 12 | 53 |
2015 May | 57 | 18 | 75 |
2015 April | 29 | 16 | 45 |
2015 March | 42 | 9 | 51 |
2015 February | 41 | 3 | 44 |
2015 January | 46 | 7 | 53 |
2014 December | 44 | 3 | 47 |
2014 November | 52 | 6 | 58 |
2014 October | 41 | 13 | 54 |
2014 September | 44 | 6 | 50 |
2014 August | 42 | 8 | 50 |
2014 July | 37 | 8 | 45 |
2014 June | 60 | 8 | 68 |
2014 May | 57 | 7 | 64 |
2014 April | 58 | 5 | 63 |
2014 March | 67 | 11 | 78 |
2014 February | 65 | 15 | 80 |
2014 January | 45 | 12 | 57 |
2013 December | 48 | 5 | 53 |
2013 November | 37 | 9 | 46 |
2013 October | 54 | 5 | 59 |
2013 September | 50 | 11 | 61 |
2013 August | 34 | 7 | 41 |
2013 July | 51 | 12 | 63 |
2013 June | 40 | 8 | 48 |
2013 May | 45 | 10 | 55 |
2013 April | 25 | 6 | 31 |
2013 March | 12 | 2 | 14 |