Original Articles
Course of Bronchial Hyperresponsiveness in Patients With Occupational Asthma Caused by Exposure to Persulfate Salts
Read
4385
Timeswas read the article
1705
Total PDF
2680
Total HTML
Share statistics
array:23 [ "pii" => "S1579212908600282" "issn" => "15792129" "doi" => "10.1016/S1579-2129(08)60028-2" "estado" => "S300" "fechaPublicacion" => "2008-01-01" "aid" => "60028" "copyright" => "Sociedad Española de Neumología y Cirugía Torácica (SEPAR)" "copyrightAnyo" => "2008" "documento" => "article" "crossmark" => 0 "subdocumento" => "fla" "cita" => "Arch Bronconeumol. 2008;44:140-5" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:2 [ "total" => 2567 "formatos" => array:3 [ "EPUB" => 103 "HTML" => 1842 "PDF" => 622 ] ] "itemSiguiente" => array:18 [ "pii" => "S1579212908600294" "issn" => "15792129" "doi" => "10.1016/S1579-2129(08)60029-4" "estado" => "S300" "fechaPublicacion" => "2008-01-01" "aid" => "60029" "copyright" => "Sociedad Española de Neumología y Cirugía Torácica (SEPAR)" "documento" => "article" "crossmark" => 0 "subdocumento" => "fla" "cita" => "Arch Bronconeumol. 2008;44:146-51" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:2 [ "total" => 3158 "formatos" => array:3 [ "EPUB" => 95 "HTML" => 2361 "PDF" => 702 ] ] "en" => array:10 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Original Articles</span>" "titulo" => "<span class="elsevierStyleItalic">Aspergillus fumigatus</span> and <span class="elsevierStyleItalic">Candida albicans</span> in Cystic Fibrosis: Clinical Significance and Specific Immune Response Involving Serum Immunoglobulins G, A, and M" "tienePdf" => "en" "tieneTextoCompleto" => 0 "tieneResumen" => array:2 [ 0 => "en" 1 => "es" ] "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "146" "paginaFinal" => "151" ] ] "contieneResumen" => array:2 [ "en" => true "es" => true ] "contienePdf" => array:1 [ "en" => true ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "Luis Máiz, Manuela Cuevas, Adelaida Lamas, Aurora Sousa, Santiago Quirce, Lucrecia Suárez" "autores" => array:6 [ 0 => array:2 [ "nombre" => "Luis" "apellidos" => "Máiz" ] 1 => array:2 [ "nombre" => "Manuela" "apellidos" => "Cuevas" ] 2 => array:2 [ "nombre" => "Adelaida" "apellidos" => "Lamas" ] 3 => array:2 [ "nombre" => "Aurora" "apellidos" => "Sousa" ] 4 => array:2 [ "nombre" => "Santiago" "apellidos" => "Quirce" ] 5 => array:2 [ "nombre" => "Lucrecia" "apellidos" => "Suárez" ] ] ] ] ] "idiomaDefecto" => "en" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1579212908600294?idApp=UINPBA00003Z" "url" => "/15792129/0000004400000003/v1_201305150345/S1579212908600294/v1_201305150345/en/main.assets" ] "itemAnterior" => array:18 [ "pii" => "S1579212908600270" "issn" => "15792129" "doi" => "10.1016/S1579-2129(08)60027-0" "estado" => "S300" "fechaPublicacion" => "2008-01-01" "aid" => "60027" "copyright" => "Sociedad Española de Neumología y Cirugía Torácica (SEPAR)" "documento" => "article" "crossmark" => 0 "subdocumento" => "fla" "cita" => "Arch Bronconeumol. 2008;44:135-9" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:2 [ "total" => 2416 "formatos" => array:3 [ "EPUB" => 92 "HTML" => 1632 "PDF" => 692 ] ] "en" => array:10 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Original Articles</span>" "titulo" => "Salbutamol Improves Diaphragm Force Generation in Experimental Sepsis" "tienePdf" => "en" "tieneTextoCompleto" => 0 "tieneResumen" => array:2 [ 0 => "en" 1 => "es" ] "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "135" "paginaFinal" => "139" ] ] "contieneResumen" => array:2 [ "en" => true "es" => true ] "contienePdf" => array:1 [ "en" => true ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "Héctor Píriz, Nicolás Nin, José Boggia, Martín Angulo, Francisco Javier Hurtado" "autores" => array:5 [ 0 => array:2 [ "nombre" => "Héctor" "apellidos" => "Píriz" ] 1 => array:2 [ "nombre" => "Nicolás" "apellidos" => "Nin" ] 2 => array:2 [ "nombre" => "José" "apellidos" => "Boggia" ] 3 => array:2 [ "nombre" => "Martín" "apellidos" => "Angulo" ] 4 => array:2 [ "nombre" => "Francisco Javier" "apellidos" => "Hurtado" ] ] ] ] ] "idiomaDefecto" => "en" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1579212908600270?idApp=UINPBA00003Z" "url" => "/15792129/0000004400000003/v1_201305150345/S1579212908600270/v1_201305150345/en/main.assets" ] "en" => array:15 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Original Articles</span>" "titulo" => "Course of Bronchial Hyperresponsiveness in Patients With Occupational Asthma Caused by Exposure to Persulfate Salts" "tieneTextoCompleto" => 0 "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "140" "paginaFinal" => "145" ] ] "autores" => array:1 [ 0 => array:4 [ "autoresLista" => "Xavier Muñoz, Susana Gómez-Ollés, María Jesús Cruz, María Dolores Untoria, Ramon Orriols, Ferran Morell" "autores" => array:6 [ 0 => array:4 [ "nombre" => "Xavier" "apellidos" => "Muñoz" "email" => array:1 [ 0 => "xmunoz@vhebron.net" ] "referencia" => array:4 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff1" ] 1 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff2" ] 2 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">c</span>" "identificador" => "aff3" ] 3 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">*</span>" "identificador" => "cor1" ] ] ] 1 => array:3 [ "nombre" => "Susana" "apellidos" => "Gómez-Ollés" "referencia" => array:2 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff1" ] 1 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff2" ] ] ] 2 => array:3 [ "nombre" => "María Jesús" "apellidos" => "Cruz" "referencia" => array:2 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff1" ] 1 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff2" ] ] ] 3 => array:3 [ "nombre" => "María Dolores" "apellidos" => "Untoria" "referencia" => array:2 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff1" ] 1 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff2" ] ] ] 4 => array:3 [ "nombre" => "Ramon" "apellidos" => "Orriols" "referencia" => array:2 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff1" ] 1 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff2" ] ] ] 5 => array:3 [ "nombre" => "Ferran" "apellidos" => "Morell" "referencia" => array:2 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff1" ] 1 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff2" ] ] ] ] "afiliaciones" => array:3 [ 0 => array:3 [ "entidad" => "Servei de Pneumologia, Hospital Vall d'Hebron, Barcelona, Spain" "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff1" ] 1 => array:3 [ "entidad" => "CIBER Enfermedades Respiratorias (CIBERES), Instituto de Salud Carlos III, Madrid, Spain" "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff2" ] 2 => array:3 [ "entidad" => "Departament de Biologia Cel·lular, Fisiologia, Immunologia, Universitat Autònoma de Barcelona, Barcelona, Spain" "etiqueta" => "<span class="elsevierStyleSup">c</span>" "identificador" => "aff3" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor1" "etiqueta" => "*" "correspondencia" => "Correspondence: Dr X. Muñoz Servei de Pneumologia, Hospital General Vall d'Hebron Pg. Vall d'Hebron, 11908035 Barcelona, Spain" ] ] ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "2007-03-17" "fechaAceptado" => "2007-07-24" "PalabrasClave" => array:2 [ "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Key words" "identificador" => "xpalclavsec155186" "palabras" => array:5 [ 0 => "Methacholine" 1 => "Skin prick test" 2 => "Follow-up monitoring" 3 => "Rhinitis" 4 => "Hairdressers" ] ] ] "es" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palabras clave" "identificador" => "xpalclavsec155187" "palabras" => array:5 [ 0 => "Metacolina" 1 => "Prueba cutánea" 2 => "Seguimiento" 3 => "Rinitis" 4 => "Profesionales de peluquería" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "en" => array:1 [ "resumen" => "<span class="elsevierStyleSectionTitle">Objective</span><p class="elsevierStyleSimplePara elsevierViewall">Persulfate salts are among the most frequently implicated causes of occupational asthma. The aim of this study was to describe the course of bronchial hyperresponsiveness and immunologic test results in patients with occupational asthma due to persulfate salts.</p> <span class="elsevierStyleSectionTitle">Patients and methods</span><p class="elsevierStyleSimplePara elsevierViewall">Ten patients with occupational asthma due to persulfate salts were studied. Diagnosis was based on specific bronchial challenge tests performed at least 3 years before enrollment. An exhaustive medical and work history was taken during interviews with all patients, and all underwent spirometry and nonspecific bronchial challenge testing. Total immunoglobulin E levels were determined and skin prick tests to several persulfate salts were performed.</p> <span class="elsevierStyleSectionTitle">Results</span><p class="elsevierStyleSimplePara elsevierViewall">At the time of evaluation, 7 patients had avoided workplace exposure to persulfate salts. The bronchial hyperresponsiveness of 3 of those 7 patients had improved significantly. No improvement was observed in patients who continued to be exposed. Specific skin prick tests became negative in 3 patients who were no longer exposed at the time of the follow-up evaluation. Most of the patients continued to report symptoms, although improvements were noted. One patient, however, reported worsening of symptoms in spite of avoidance of exposure.</p> <span class="elsevierStyleSectionTitle">Conclusions</span><p class="elsevierStyleSimplePara elsevierViewall">Although asthma symptoms and bronchial hyperresponsiveness may persist for patients with occupational asthma due to persulfate salts, their condition seems to improve if they avoid exposure. This course does not seem to differ from that reported for other cases of occupational asthma.</p>" ] "es" => array:1 [ "resumen" => "<span class="elsevierStyleSectionTitle">Objetivo</span><p class="elsevierStyleSimplePara elsevierViewall">Las sales de persulfato son uno de los agentes más frecuentemente implicados en el origen del asma ocupacional (AO). El objetivo de este estudio ha sido establecer la evolución de la hiperrespuesta bronquial y de las pruebas inmunológicas en pacientes con AO por persulfatos en función de que persista o no la exposición a dichas sales.</p> <span class="elsevierStyleSectionTitle">Pacientes y métodos</span><p class="elsevierStyleSimplePara elsevierViewall">Se estudió a 10 pacientes con AO por exposición a sales de persulfato, diagnosticados con prueba de provocación bronquial específica, en los que como mínimo habían transcurrido 3 años tras el diagnóstico. En todos los casos se realizaron un exhaustivo interrogatorio clínico y laboral, espirometría forzada y prueba de provocación bronquial inespecífica con metacolina, se determinaron los valores de inmunoglobulina E total y se practicaron pruebas cutáneas con las distintas sales de persulfato.</p> <span class="elsevierStyleSectionTitle">Resultados</span><p class="elsevierStyleSimplePara elsevierViewall">En el momento del control evolutivo, 7 pacientes habían abandonado la exposición a persulfatos. De los pacientes con hiperrespuesta bronquial positiva que habían abandonado el trabajo, se observó una mejoría significativa de ésta en 3 de ellos. Este hecho no se observó en ninguno de los pacientes que siguieron expuestos. La prueba cutánea específica se negativizó en 3 pacientes que no estaban expuestos en el momento del control evolutivo. Desde el punto de vista clínico, la mayoría de los pacientes continuaron presentando síntomas, aunque éstos habían mejorado, excepto en un caso en que, a pesar de evitar la exposición, empeoraron.</p> <span class="elsevierStyleSectionTitle">Conclusiones</span><p class="elsevierStyleSimplePara elsevierViewall">Aunque pueden persistir los síntomas de asma y la hiperrespuesta bronquial positiva, la evolución de los pacientes con AO por persulfato parece ser favorable si se evita la exposición. Esta respuesta no parece diferir de la comunicada en otros casos de AO.</p>" ] ] "NotaPie" => array:1 [ 0 => array:1 [ "nota" => "<p class="elsevierStyleNotepara">This study was partly funded by grant number FIS PI050100 from the Carlos III Institute of Health.</p>" ] ] "bibliografia" => array:2 [ "titulo" => "References" "seccion" => array:1 [ 0 => array:1 [ "bibliografiaReferencia" => array:42 [ 0 => array:3 [ "identificador" => "bib1" "etiqueta" => "1" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Incidence by occupation and industry of acute work related respiratory diseases in the UK, 1992–2001" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "JC McDonald" 1 => "Y Chen" 2 => "C Zekveld" 3 => "NM Cherry" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1136/oem.2004.019489" "Revista" => array:6 [ "tituloSerie" => "Occup Environ Med" "fecha" => "2005" "volumen" => "62" "paginaInicial" => "836" "paginaFinal" => "842" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16299091" "web" => "Medline" ] ] ] ] ] ] ] ] 1 => array:3 [ "identificador" => "bib2" "etiqueta" => "2" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Physician based surveillance system for occupational respiratory diseases: the experience of PROPULSE, Quebec, Canada" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "S Provencher" 1 => "FP Labrece" 2 => "L de Guire" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Occup Environ Med" "fecha" => "1997" "volumen" => "41" "paginaInicial" => "272" "paginaFinal" => "276" ] ] ] ] ] ] 2 => array:3 [ "identificador" => "bib3" "etiqueta" => "3" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Occupational asthma in, Finland" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "H Keskinen" 1 => "K Alanko" 2 => "L Saarinen" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Clin Allergy" "fecha" => "1978" "volumen" => "8" "paginaInicial" => "569" "paginaFinal" => "579" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/709801" "web" => "Medline" ] ] ] ] ] ] ] ] 3 => array:3 [ "identificador" => "bib4" "etiqueta" => "4" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Reported incidence of occupational asthma in France, 1996–99: the ONAP programme" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:7 [ 0 => "J Ameille" 1 => "G Pauli" 2 => "A Calastreng-Crinquand" 3 => "D Vervloët" 4 => "Y Iwatsubo" 5 => "E Popin" 6 => "the corresponding members of the ONAP" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Occup Environ Med" "fecha" => "2003" "volumen" => "60" "paginaInicial" => "136" "paginaFinal" => "141" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12554842" "web" => "Medline" ] ] ] ] ] ] ] ] 4 => array:3 [ "identificador" => "bib5" "etiqueta" => "5" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "members of the Malaltia Ocupacional Respiratòria (MOR) Group. Reported occupational respiratory diseases in Catalonia" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "R Orriols" 1 => "R Costa" 2 => "M Albanell" 3 => "C Alberti" 4 => "J Castejón" 5 => "E Monsó" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1136/oem.2005.022525" "Revista" => array:6 [ "tituloSerie" => "Occup Environ Med" "fecha" => "2006" "volumen" => "63" "paginaInicial" => "255" "paginaFinal" => "260" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16556745" "web" => "Medline" ] ] ] ] ] ] ] ] 5 => array:3 [ "identificador" => "bib6" "etiqueta" => "6" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Occupational asthma in France: a 1-yr reported of the Observatoire National de Asthmes Professionnels project" "autores" => array:1 [ 0 => array:3 [ "colaboracion" => "Observatoire National de Asthmes Professionnels Groupe" "etal" => true "autores" => array:6 [ 0 => "MC Kopferschmitt-Kubler" 1 => "J Ameille" 2 => "E Popin" 3 => "A Calastreng-Crinquand" 4 => "D Vervloet" 5 => "MC Bayeux-Dunglas" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Eur Respir J" "fecha" => "2002" "volumen" => "19" "paginaInicial" => "84" "paginaFinal" => "89" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11843332" "web" => "Medline" ] ] ] ] ] ] ] ] 6 => array:3 [ "identificador" => "bib7" "etiqueta" => "7" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Occupational asthma in a hairdressing salon" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "AD Blainey" 1 => "S Ollier" 2 => "D Cundell" 3 => "RE Smith" 4 => "RJ Davies" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Thorax" "fecha" => "1986" "volumen" => "41" "paginaInicial" => "42" "paginaFinal" => "50" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/3704965" "web" => "Medline" ] ] ] ] ] ] ] ] 7 => array:3 [ "identificador" => "bib8" "etiqueta" => "8" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Asthma in hairdressers: a report of 5 cases" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "P Macchioni" 1 => "C Kotopoulus" 2 => "D Talini" 3 => "M De Santis" 4 => "E Masino" 5 => "PL Paggiaro" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Med Lav" "fecha" => "1999" "volumen" => "90" "paginaInicial" => "776" "paginaFinal" => "785" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10703193" "web" => "Medline" ] ] ] ] ] ] ] ] 8 => array:3 [ "identificador" => "bib9" "etiqueta" => "9" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Occupational asthma due to persulfate salts. Diagnosis and followup" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "X Muñoz" 1 => "MJ Cruz" 2 => "R Orriols" 3 => "C Bravo" 4 => "M Espuga" 5 => "F Morell" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Chest" "fecha" => "2003" "volumen" => "123" "paginaInicial" => "2124" "paginaFinal" => "2129" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12796198" "web" => "Medline" ] ] ] ] ] ] ] ] 9 => array:3 [ "identificador" => "bib10" "etiqueta" => "10" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Occupational asthma and occupational rhinitis in hairdressers" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "G Moscato" 1 => "P Pignatti" 2 => "MR Yacoub" 3 => "C Romano" 4 => "S Spezia" 5 => "L Perfetti" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1378/chest.128.5.3590" "Revista" => array:6 [ "tituloSerie" => "Chest" "fecha" => "2005" "volumen" => "128" "paginaInicial" => "3590" "paginaFinal" => "3598" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16304318" "web" => "Medline" ] ] ] ] ] ] ] ] 10 => array:3 [ "identificador" => "bib11" "etiqueta" => "11" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Evidence based guidelines for the prevention, identification, and management of occupational asthma" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "PJ Nicholson" 1 => "P Cullinan" 2 => "AJ Taylor" 3 => "PS Burge" 4 => "C Boyle" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1136/oem.2004.016287" "Revista" => array:6 [ "tituloSerie" => "Occup Environ Med" "fecha" => "2005" "volumen" => "62" "paginaInicial" => "290" "paginaFinal" => "299" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15837849" "web" => "Medline" ] ] ] ] ] ] ] ] 11 => array:3 [ "identificador" => "bib12" "etiqueta" => "12" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The outcome of occupational asthma after cessation of exposure: a systematic review" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "G Rachiotis" 1 => "R Savani" 2 => "A Brant" 3 => "SJ MacNeill" 4 => "A Newman Taylor" 5 => "P Cullinan" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1136/thx.2006.061952" "Revista" => array:6 [ "tituloSerie" => "Thorax" "fecha" => "2007" "volumen" => "62" "paginaInicial" => "147" "paginaFinal" => "152" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/17040933" "web" => "Medline" ] ] ] ] ] ] ] ] 12 => array:3 [ "identificador" => "bib13" "etiqueta" => "13" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Validation of specific inhalation challenge for the diagnosis of occupational asthma due to persulfate salts" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "X Muñoz" 1 => "MJ Cruz" 2 => "R Orriols" 3 => "F Torres" 4 => "M Espuga" 5 => "F Morell" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1136/oem.2004.013177" "Revista" => array:6 [ "tituloSerie" => "Occup Environ Med" "fecha" => "2004" "volumen" => "61" "paginaInicial" => "861" "paginaFinal" => "866" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15377773" "web" => "Medline" ] ] ] ] ] ] ] ] 13 => array:3 [ "identificador" => "bib14" "etiqueta" => "14" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Effects of long term treatment with corticosteroids in COPD" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "TEJ Renkema" 1 => "JP Schouten" 2 => "GH Keter" 3 => "DS Postma" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Chest" "fecha" => "1996" "volumen" => "109" "paginaInicial" => "1156" "paginaFinal" => "1162" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8625660" "web" => "Medline" ] ] ] ] ] ] ] ] 14 => array:3 [ "identificador" => "bib15" "etiqueta" => "15" "referencia" => array:1 [ 0 => array:1 [ "referenciaCompleta" => "Global Strategy for Asthma Management and Prevention. NHL-BI/WHO Workshop report. NHI publication 1995, N 02-3659. Update of Executive Committee Report in 2002. p.136. Available from: <a class="elsevierStyleInterRef" href="http://www.ginasthma.com">www.ginasthma.com</a>" ] ] ] 15 => array:3 [ "identificador" => "bib16" "etiqueta" => "16" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Normativa para la espirometría forzada. Recomendaciones SEPAR núm. 1. Barcelona: Ediciones Doyma SA; 1985" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "J Sanchís Aldás" 1 => "P Casan Clará" 2 => "J Castillo Gómez" 3 => "N Gómez Mangado" 4 => "L Palenciano Ballesteros" 5 => "J Roca Torrent" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Arch Bronconeumol" "fecha" => "1989" "volumen" => "25" "paginaInicial" => "132" "paginaFinal" => "142" ] ] ] ] ] ] 16 => array:3 [ "identificador" => "bib17" "etiqueta" => "17" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Spirometric reference values from a Mediterranean population" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "J Roca" 1 => "J Sanchís" 2 => "A Agustí-Vidal" 3 => "F Segarra" 4 => "D Navajas" 5 => "R Rodríguez-Roisin" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Bull Eur Physiopathol Respir" "fecha" => "1986" "volumen" => "22" "paginaInicial" => "217" "paginaFinal" => "224" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/3730638" "web" => "Medline" ] ] ] ] ] ] ] ] 17 => array:3 [ "identificador" => "bib18" "etiqueta" => "18" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Standardization of bronchial inhalation challenge procedures" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "H Chai" 1 => "R Farr" 2 => "LA Froehlich" 3 => "DA Mathison" 4 => "JA McLean" 5 => "RR Rosenthal" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "J Allergy Clin Immunol" "fecha" => "1975" "volumen" => "56" "paginaInicial" => "323" "paginaFinal" => "327" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/1176724" "web" => "Medline" ] ] ] ] ] ] ] ] 18 => array:3 [ "identificador" => "bib19" "etiqueta" => "19" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Airways responsiveness. Standardized challenge testing with pharmacological, physical and sensitizing stimuli in adults" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "PJ Sterk" 1 => "LM Fabbri" 2 => "PhH Quanjer" 3 => "DW Cockcroft" 4 => "PM O'Byrne" 5 => "SD Anderson" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:7 [ "tituloSerie" => "Eur Respir J" "fecha" => "1993" "volumen" => "6" "numero" => "Suppl" "paginaInicial" => "53" "paginaFinal" => "83" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8425595" "web" => "Medline" ] ] ] ] ] ] ] ] 19 => array:3 [ "identificador" => "bib20" "etiqueta" => "20" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Follow-up of occupational asthma after removal from or diminution of exposure to the responsible agent" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "L Perfetti" 1 => "A Cartier" 2 => "H Ghezzo" 3 => "D Gautrin" 4 => "JL Malo" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Chest" "fecha" => "1998" "volumen" => "114" "paginaInicial" => "398" "paginaFinal" => "403" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9726721" "web" => "Medline" ] ] ] ] ] ] ] ] 20 => array:3 [ "identificador" => "bib21" "etiqueta" => "21" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Skin test in diagnosis" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "J Pepys" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "LibroEditado" => array:5 [ "titulo" => "Clinical aspects of immunology" "paginaInicial" => "55" "paginaFinal" => "80" "edicion" => "3rd ed." "serieFecha" => "1975" ] ] ] ] ] ] 21 => array:3 [ "identificador" => "bib22" "etiqueta" => "22" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Increased positivity of skin test and allergenic stability of glycerinated soybean hull extracts" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "F Morell" 1 => "R Codina" 2 => "MJ Rodrigo" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Clin Exp Allergy" "fecha" => "1999" "volumen" => "29" "paginaInicial" => "388" "paginaFinal" => "393" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10202348" "web" => "Medline" ] ] ] ] ] ] ] ] 22 => array:3 [ "identificador" => "bib23" "etiqueta" => "23" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Occupational asthma due to persulfate salts" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "X Muñoz" 1 => "MJ Cruz" 2 => "R Orriols" 3 => "C Bravo" 4 => "M Espuga" 5 => "F Morell" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Chest" "fecha" => "2003" "volumen" => "123" "paginaInicial" => "2122" "paginaFinal" => "2127" ] ] ] ] ] ] 23 => array:3 [ "identificador" => "bib24" "etiqueta" => "24" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Follow-up study of 232 patients with occupational asthma caused by Western red cedar (<span class="elsevierStyleItalic">Thuja plicata</span>)" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "M Chan-Yeung" 1 => "L Maclean" 2 => "PL Paggiaro" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "J Allergy Clin Immunol" "fecha" => "1987" "volumen" => "79" "paginaInicial" => "792" "paginaFinal" => "796" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/3571771" "web" => "Medline" ] ] ] ] ] ] ] ] 24 => array:3 [ "identificador" => "bib25" "etiqueta" => "25" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Prognosis of occupational asthma" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "PL Paggiaro" 1 => "B Vagaggani" 2 => "E Bacci" 3 => "L Bancalari" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Eur Respir J" "fecha" => "1994" "volumen" => "7" "paginaInicial" => "761" "paginaFinal" => "767" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8005260" "web" => "Medline" ] ] ] ] ] ] ] ] 25 => array:3 [ "identificador" => "bib26" "etiqueta" => "26" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Follow up study of patients with respiratory disease due to TDI" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "PL Paggiaro" 1 => "AM Loi" 2 => "O Rossi" 3 => "B Ferrante" 4 => "F Pardi" 5 => "MG Roselli" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Clin Allergy" "fecha" => "1984" "volumen" => "14" "paginaInicial" => "463" "paginaFinal" => "469" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/6091946" "web" => "Medline" ] ] ] ] ] ] ] ] 26 => array:3 [ "identificador" => "bib27" "etiqueta" => "27" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Clinical features and natural history of occupational asthma due to red cedar <span class="elsevierStyleItalic">(Thuja plicata).</span>" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "M Chan-Yeung" 1 => "S Lam" 2 => "S Koener" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Am J Med" "fecha" => "1982" "volumen" => "72" "paginaInicial" => "411" "paginaFinal" => "415" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/7058838" "web" => "Medline" ] ] ] ] ] ] ] ] 27 => array:3 [ "identificador" => "bib28" "etiqueta" => "28" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Clinical and socio-professional fate of isocyanate-induced asthma" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "N Rosenberg" 1 => "R Garnier" 2 => "X Rousselin" 3 => "R Mertz" 4 => "P Gervais" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Clin Allergy" "fecha" => "1987" "volumen" => "17" "paginaInicial" => "55" "paginaFinal" => "61" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/3829371" "web" => "Medline" ] ] ] ] ] ] ] ] 28 => array:3 [ "identificador" => "bib29" "etiqueta" => "29" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Outcome of patients with red cedar asthma with continuous exposure" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "J Côté" 1 => "S Kennedy" 2 => "M Chan-Yeung" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1164/ajrccm/141.2.373" "Revista" => array:6 [ "tituloSerie" => "Am Rev Respir Dis" "fecha" => "1990" "volumen" => "141" "paginaInicial" => "373" "paginaFinal" => "376" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/1689129" "web" => "Medline" ] ] ] ] ] ] ] ] 29 => array:3 [ "identificador" => "bib30" "etiqueta" => "30" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Occupational asthma. A longitudinal study on the clinical and socioeconomic outcome after diagnosis" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "G Moscato" 1 => "A Dellabianca" 2 => "L Perfetti" 3 => "B Bramè" 4 => "E Galdi" 5 => "R Niniano" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Chest" "fecha" => "1999" "volumen" => "115" "paginaInicial" => "249" "paginaFinal" => "256" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9925092" "web" => "Medline" ] ] ] ] ] ] ] ] 30 => array:3 [ "identificador" => "bib31" "etiqueta" => "31" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Asma ocupacional por isocianatos: estudio de 21 pacientes" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "R Orriols" 1 => "ME Drobnic" 2 => "X Muñoz" 3 => "MJ Rodrigo" 4 => "F Morell" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Med Clin (Barc)" "fecha" => "1999" "volumen" => "113" "paginaInicial" => "659" "paginaFinal" => "662" ] ] ] ] ] ] 31 => array:3 [ "identificador" => "bib32" "etiqueta" => "32" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Recovery of methacholine responsiveness after end of exposure in occupational asthma" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "JL Malo" 1 => "H Ghezzo" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1164/rccm.200312-1749OC" "Revista" => array:6 [ "tituloSerie" => "Am J Respir Crit Care Med" "fecha" => "2004" "volumen" => "169" "paginaInicial" => "1304" "paginaFinal" => "1307" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15070824" "web" => "Medline" ] ] ] ] ] ] ] ] 32 => array:3 [ "identificador" => "bib33" "etiqueta" => "33" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Long-term follow-up of toluene diisocyanate-induced asthma" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "M Padoan" 1 => "V Pozzato" 2 => "M Simoni" 3 => "L Zedda" 4 => "G Milan" 5 => "J Bononi" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Eur Respir J" "fecha" => "2003" "volumen" => "21" "paginaInicial" => "637" "paginaFinal" => "640" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12762349" "web" => "Medline" ] ] ] ] ] ] ] ] 33 => array:3 [ "identificador" => "bib34" "etiqueta" => "34" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Occupational asthma due to various agents. Absence of clinical and functional improvement at an interval of four or more years after cessation of exposure" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "C Allard" 1 => "A Cartier" 2 => "H Ghezzo" 3 => "JL Malo" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Chest" "fecha" => "1989" "volumen" => "96" "paginaInicial" => "1046" "paginaFinal" => "1049" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/2805834" "web" => "Medline" ] ] ] ] ] ] ] ] 34 => array:3 [ "identificador" => "bib35" "etiqueta" => "35" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Nonspecific and specific bronchial responsiveness in occupational asthma caused by platinum salts after allergen avoidance" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "R Merget" 1 => "M Reineke" 2 => "A Rueckmann" 3 => "EM Bergmann" 4 => "G Schultze-Werninghaus" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1164/ajrccm.150.4.7921450" "Revista" => array:6 [ "tituloSerie" => "Am J Respir Crit Care Med" "fecha" => "1994" "volumen" => "150" "paginaInicial" => "1146" "paginaFinal" => "1149" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/7921450" "web" => "Medline" ] ] ] ] ] ] ] ] 35 => array:3 [ "identificador" => "bib36" "etiqueta" => "36" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Follow-up of occupational asthma after removal from or diminution of exposure to the responsible agent: relevance of the length of the interval from cessation of exposure" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "L Perfetti" 1 => "A Cartier" 2 => "H Ghezzo" 3 => "D Gautrin" 4 => "JL Malo" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Chest" "fecha" => "1998" "volumen" => "114" "paginaInicial" => "398" "paginaFinal" => "403" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9726721" "web" => "Medline" ] ] ] ] ] ] ] ] 36 => array:3 [ "identificador" => "bib37" "etiqueta" => "37" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Airway inflammation after cessation of exposure to agents causing occupational asthma" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "K Maghni" 1 => "C Lemière" 2 => "H Ghezzo" 3 => "W Yuquan" 4 => "JL Malo" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1164/rccm.200309-1238OC" "Revista" => array:6 [ "tituloSerie" => "Am J Respir Crit Care Med" "fecha" => "2004" "volumen" => "169" "paginaInicial" => "367" "paginaFinal" => "372" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/14578217" "web" => "Medline" ] ] ] ] ] ] ] ] 37 => array:3 [ "identificador" => "bib38" "etiqueta" => "38" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Occupational asthma caused by natural rubber latex: outcome according to cessation or reduction of exposure" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "O Vandenplas" 1 => "J Jamart" 2 => "JP Delwiche" 3 => "G Evrard" 4 => "A Larbanois" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "J Allergy Clin Immunol" "fecha" => "2002" "volumen" => "109" "paginaInicial" => "125" "paginaFinal" => "130" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11799378" "web" => "Medline" ] ] ] ] ] ] ] ] 38 => array:3 [ "identificador" => "bib39" "etiqueta" => "39" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Outcomes in occupational asthma caused by reactive dye after long-term avoidance" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "HW Park" 1 => "DI Kim" 2 => "SW Sohn" 3 => "CH Park" 4 => "SS Kim" 5 => "YS Chang" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1111/j.1365-2222.2007.02641.x" "Revista" => array:6 [ "tituloSerie" => "Clin Exp Allergy" "fecha" => "2007" "volumen" => "37" "paginaInicial" => "225" "paginaFinal" => "230" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/17250695" "web" => "Medline" ] ] ] ] ] ] ] ] 39 => array:3 [ "identificador" => "bib40" "etiqueta" => "40" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Patterns of improvement in spirometry, bronchial hyperresponsiveness, and specific IgE antibody levels after cessation of exposure in occupational asthma caused by snow crab processing" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "JL Malo" 1 => "A Cartier" 2 => "H Ghezzo" 3 => "M la France" 4 => "M McCants" 5 => "SB Lehrer" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1164/ajrccm/138.4.807" "Revista" => array:6 [ "tituloSerie" => "Am Rev Respir Dis" "fecha" => "1988" "volumen" => "138" "paginaInicial" => "807" "paginaFinal" => "812" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/3202454" "web" => "Medline" ] ] ] ] ] ] ] ] 40 => array:3 [ "identificador" => "bib41" "etiqueta" => "41" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Occupational asthma caused by tetrachlorophthalic anhydride: a 12-year follow-up" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "RD Barker" 1 => "JM Harris" 2 => "JA Welch" 3 => "KM Venables" 4 => "AJ Newman Taylor" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "J Allergy Clin Immunol" "fecha" => "1998" "volumen" => "101" "paginaInicial" => "717" "paginaFinal" => "719" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9648696" "web" => "Medline" ] ] ] ] ] ] ] ] 41 => array:3 [ "identificador" => "bib42" "etiqueta" => "42" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Long-term antibody production after lung immunization and challenge: role of lung and lymphoid tissues" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "DE Bice" 1 => "SE Jones" 2 => "BA Muggenburg" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Am J Respir Cell Mol Biol" "fecha" => "1993" "volumen" => "6" "paginaInicial" => "662" "paginaFinal" => "667" ] ] ] ] ] ] ] ] ] ] ] "idiomaDefecto" => "en" "url" => "/15792129/0000004400000003/v1_201305150345/S1579212908600282/v1_201305150345/en/main.assets" "Apartado" => null "PDF" => "https://static.elsevier.es/multimedia/15792129/0000004400000003/v1_201305150345/S1579212908600282/v1_201305150345/en/main.pdf?idApp=UINPBA00003Z&text.app=https://archbronconeumol.org/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1579212908600282?idApp=UINPBA00003Z" ]
| Year/Month | Html | Total | |
|---|---|---|---|
| 2024 November | 7 | 1 | 8 |
| 2024 October | 28 | 18 | 46 |
| 2024 September | 23 | 15 | 38 |
| 2024 August | 42 | 30 | 72 |
| 2024 July | 28 | 23 | 51 |
| 2024 June | 40 | 26 | 66 |
| 2024 May | 38 | 30 | 68 |
| 2024 April | 23 | 25 | 48 |
| 2024 March | 26 | 17 | 43 |
| 2024 February | 17 | 18 | 35 |
| 2024 January | 1 | 0 | 1 |
| 2023 March | 2 | 2 | 4 |
| 2023 February | 16 | 15 | 31 |
| 2023 January | 17 | 24 | 41 |
| 2022 December | 18 | 28 | 46 |
| 2022 November | 19 | 20 | 39 |
| 2022 October | 20 | 29 | 49 |
| 2022 September | 18 | 16 | 34 |
| 2022 August | 21 | 38 | 59 |
| 2022 July | 21 | 41 | 62 |
| 2022 June | 16 | 27 | 43 |
| 2022 May | 15 | 25 | 40 |
| 2022 April | 14 | 32 | 46 |
| 2022 March | 19 | 31 | 50 |
| 2022 February | 15 | 26 | 41 |
| 2022 January | 16 | 32 | 48 |
| 2021 December | 14 | 46 | 60 |
| 2021 November | 17 | 42 | 59 |
| 2021 October | 23 | 52 | 75 |
| 2021 September | 19 | 55 | 74 |
| 2021 August | 12 | 37 | 49 |
| 2021 July | 17 | 29 | 46 |
| 2021 June | 7 | 22 | 29 |
| 2021 May | 19 | 19 | 38 |
| 2021 April | 30 | 25 | 55 |
| 2021 March | 16 | 21 | 37 |
| 2021 February | 18 | 12 | 30 |
| 2021 January | 14 | 15 | 29 |
| 2020 December | 7 | 7 | 14 |
| 2020 November | 11 | 13 | 24 |
| 2020 October | 11 | 5 | 16 |
| 2020 September | 9 | 7 | 16 |
| 2020 August | 12 | 15 | 27 |
| 2020 July | 10 | 13 | 23 |
| 2020 June | 9 | 5 | 14 |
| 2020 May | 14 | 15 | 29 |
| 2020 April | 14 | 23 | 37 |
| 2020 March | 8 | 12 | 20 |
| 2020 February | 18 | 12 | 30 |
| 2020 January | 27 | 15 | 42 |
| 2019 December | 13 | 18 | 31 |
| 2019 November | 12 | 9 | 21 |
| 2019 October | 9 | 9 | 18 |
| 2019 September | 17 | 10 | 27 |
| 2019 August | 13 | 12 | 25 |
| 2019 July | 9 | 24 | 33 |
| 2019 June | 5 | 10 | 15 |
| 2019 May | 13 | 6 | 19 |
| 2019 April | 15 | 29 | 44 |
| 2019 March | 17 | 9 | 26 |
| 2019 February | 12 | 11 | 23 |
| 2019 January | 12 | 5 | 17 |
| 2018 December | 11 | 18 | 29 |
| 2018 November | 27 | 11 | 38 |
| 2018 October | 40 | 16 | 56 |
| 2018 September | 19 | 10 | 29 |
| 2018 May | 5 | 0 | 5 |
| 2018 April | 9 | 6 | 15 |
| 2018 March | 6 | 3 | 9 |
| 2018 February | 9 | 6 | 15 |
| 2018 January | 3 | 5 | 8 |
| 2017 December | 6 | 5 | 11 |
| 2017 November | 5 | 5 | 10 |
| 2017 October | 6 | 7 | 13 |
| 2017 September | 2 | 6 | 8 |
| 2017 August | 9 | 11 | 20 |
| 2017 July | 19 | 12 | 31 |
| 2017 June | 11 | 26 | 37 |
| 2017 May | 7 | 4 | 11 |
| 2017 April | 5 | 7 | 12 |
| 2017 March | 3 | 8 | 11 |
| 2017 February | 3 | 2 | 5 |
| 2017 January | 2 | 2 | 4 |
| 2016 December | 7 | 3 | 10 |
| 2016 November | 13 | 5 | 18 |
| 2016 October | 10 | 12 | 22 |
| 2016 September | 6 | 6 | 12 |
| 2016 August | 7 | 3 | 10 |
| 2016 July | 11 | 5 | 16 |
| 2016 March | 2 | 0 | 2 |
| 2015 December | 2 | 0 | 2 |
| 2015 October | 41 | 13 | 54 |
| 2015 September | 43 | 10 | 53 |
| 2015 August | 47 | 9 | 56 |
| 2015 July | 63 | 6 | 69 |
| 2015 June | 42 | 12 | 54 |
| 2015 May | 48 | 17 | 65 |
| 2015 April | 45 | 7 | 52 |
| 2015 March | 38 | 7 | 45 |
| 2015 February | 36 | 4 | 40 |
| 2015 January | 43 | 2 | 45 |
| 2014 December | 44 | 4 | 48 |
| 2014 November | 47 | 3 | 50 |
| 2014 October | 51 | 10 | 61 |
| 2014 September | 38 | 6 | 44 |
| 2014 August | 40 | 6 | 46 |
| 2014 July | 37 | 5 | 42 |
| 2014 June | 50 | 5 | 55 |
| 2014 May | 55 | 13 | 68 |
| 2014 April | 58 | 7 | 65 |
| 2014 March | 56 | 9 | 65 |
| 2014 February | 59 | 10 | 69 |
| 2014 January | 36 | 5 | 41 |
| 2013 December | 39 | 8 | 47 |
| 2013 November | 28 | 8 | 36 |
| 2013 October | 50 | 7 | 57 |
| 2013 September | 35 | 10 | 45 |
| 2013 August | 53 | 8 | 61 |
| 2013 July | 45 | 9 | 54 |
| 2013 June | 42 | 7 | 49 |
| 2013 May | 40 | 8 | 48 |
| 2013 April | 35 | 6 | 41 |
| 2013 March | 8 | 2 | 10 |
Show all
