Case Reports
Prolonged Therapeutic Response to Voriconazole in a Case of Allergic Bronchopulmonary Aspergillosis
Rafael Bandrés Gimeno
, María José Muñoz Martínez
Corresponding author
rafaelbandres@yahoo.es
Correspondence: Dr. R. Bandrés Gimeno. Servicio de Neumología. Hospital Xeral de Vigo. Complexo HospitalarioUniversitario de Vigo. Pizarro, 22. 36204 Vigo. Pontevedra. España
Correspondence: Dr. R. Bandrés Gimeno. Servicio de Neumología. Hospital Xeral de Vigo. Complexo HospitalarioUniversitario de Vigo. Pizarro, 22. 36204 Vigo. Pontevedra. España
Servicio de Neumología, Hospital Xeral de Vigo, Complexo Hospitalario Universitario de Vigo, Vigo, Pontevedra, Spain
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Bandrés Gimeno. Servicio de Neumología. Hospital Xeral de Vigo. Complexo HospitalarioUniversitario de Vigo. Pizarro, 22. 36204 Vigo. Pontevedra. España" ] ] ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "2006-02-02" "fechaAceptado" => "2006-04-04" "PalabrasClave" => array:2 [ "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Key words" "identificador" => "xpalclavsec154595" "palabras" => array:5 [ 0 => "Bronchopulmonary aspergillosis" 1 => "Aspergillosis" 2 => "Aspergillus species" 3 => "Voriconazole" 4 => "Therapeutics" ] ] ] "es" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palabras clave" "identificador" => "xpalclavsec154596" "palabras" => array:5 [ 0 => "Aspergilosis broncopulmonar alérgica" 1 => "Aspergilosis" 2 => "Aspergillus" 3 => "Voriconazol" 4 => "Tratamiento" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "en" => array:1 [ "resumen" => "<p class="elsevierStyleSimplePara elsevierViewall">Allergic bronchopulmonary aspergillosis is a lung disease characterized by an immune response to several antigens of Aspergillus species. Corticosteroids are the treatment of choice in the acute phase, although some studies have shown the efficacy of itraconazole. We describe the case of a favorable, prolonged therapeutic response to voriconazole in a patient with allergic bronchopulmonary aspergillosis who did not tolerate itraconazole.</p>" ] "es" => array:1 [ "resumen" => "<p class="elsevierStyleSimplePara elsevierViewall">La aspergilosis broncopulmonar alérgica es una enferme-dad pulmonar que se caracteriza por una respuesta inmuno-lógica a múltiples antígenos de la especie Aspergillus. El tra-tamiento de elección en la fase aguda son los corticoides, pero algunos estudios han demostrado la eficacia del itraco-nazol. Describimos un caso de respuesta terapéutica favorable y prolongada con voriconazol en una paciente con broncoaspergilosis alérgica que no toleró el itraconazol.</p>" ] ] "bibliografia" => array:2 [ "titulo" => "REFERENCES" "seccion" => array:1 [ 0 => array:1 [ "bibliografiaReferencia" => array:14 [ 0 => array:3 [ "identificador" => "bib1" "etiqueta" => "1" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Allergic bronchopulmonary aspergillosis and the evaluation of the patient with asthma" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "PA Greenberger" 1 => "R Patterson" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "J Allergy Clin Immunol" "fecha" => "1988" "volumen" => "81" "paginaInicial" => "646" "paginaFinal" => "650" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/3356845" "web" => "Medline" ] ] ] ] ] ] ] ] 1 => array:3 [ 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| 2015 January | 30 | 4 | 34 |
| 2014 December | 37 | 4 | 41 |
| 2014 November | 46 | 3 | 49 |
| 2014 October | 65 | 10 | 75 |
| 2014 September | 48 | 6 | 54 |
| 2014 August | 51 | 9 | 60 |
| 2014 July | 51 | 8 | 59 |
| 2014 June | 51 | 5 | 56 |
| 2014 May | 47 | 7 | 54 |
| 2014 April | 63 | 5 | 68 |
| 2014 March | 78 | 5 | 83 |
| 2014 February | 54 | 10 | 64 |
| 2014 January | 50 | 7 | 57 |
| 2013 December | 45 | 6 | 51 |
| 2013 November | 39 | 3 | 42 |
| 2013 October | 37 | 9 | 46 |
| 2013 September | 32 | 6 | 38 |
| 2013 August | 35 | 5 | 40 |
| 2013 July | 50 | 11 | 61 |
| 2013 June | 33 | 8 | 41 |
| 2013 May | 37 | 2 | 39 |
| 2013 April | 29 | 4 | 33 |
| 2013 March | 7 | 1 | 8 |
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