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Radiographic Staging and Bronchoalveolar Lavage Cell Counts in Sarcoidosis
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Rodríguez Martínez, M.P. Sossa" "autores" => array:2 [ 0 => array:3 [ "preGrado" => "Dr." "nombre" => "C." "apellidos" => "Rodríguez Martínez" ] 1 => array:2 [ "nombre" => "M.P." "apellidos" => "Sossa" ] ] ] ] ] "idiomaDefecto" => "en" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1579212906602565?idApp=UINPBA00003Z" "url" => "/15792129/0000004100000008/v1_201305150223/S1579212906602565/v1_201305150223/en/main.assets" ] "en" => array:14 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Original Articles</span>" "titulo" => "Radiographic Staging and Bronchoalveolar Lavage Cell Counts in Sarcoidosis" "tieneTextoCompleto" => 0 "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "425" "paginaFinal" => "429" ] ] "autores" => array:1 [ 0 => array:4 [ "autoresLista" => "S. Vidal Serrano, J. Martín Juan, L. Gómez Izquierdo, I. Sánchez Rodríguez, E. Rodríguez Becerra, F. Rodríguez Panadero" "autores" => array:6 [ 0 => array:5 [ "preGrado" => "Dra." "nombre" => "S." "apellidos" => "Vidal Serrano" "email" => array:1 [ 0 => "svidals@telefonica.net" ] "referencia" => array:2 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff1" ] 1 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">*</span>" "identificador" => "cor1" ] ] ] 1 => array:3 [ "nombre" => "J." "apellidos" => "Martín Juan" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff1" ] ] ] 2 => array:3 [ "nombre" => "L." "apellidos" => "Gómez Izquierdo" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff2" ] ] ] 3 => array:3 [ "nombre" => "I." "apellidos" => "Sánchez Rodríguez" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">c</span>" "identificador" => "aff3" ] ] ] 4 => array:3 [ "nombre" => "E." "apellidos" => "Rodríguez Becerra" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff1" ] ] ] 5 => array:3 [ "nombre" => "F." "apellidos" => "Rodríguez Panadero" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff1" ] ] ] ] "afiliaciones" => array:3 [ 0 => array:3 [ "entidad" => "Unidad Médico-Quirúrgica de Enfermedades Respiratorias, Hospital Universitario Virgen del Rocío, Sevilla, Spain" "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff1" ] 1 => array:3 [ "entidad" => "Departamento de Anatomía Patológica, Hospital Universitario Virgen del Rocío, Sevilla, Spain" "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff2" ] 2 => array:3 [ "entidad" => "Sección de Neumología, Hospital Juan Ramón Jiménez, Huelva, Spain" "etiqueta" => "<span class="elsevierStyleSup">c</span>" "identificador" => "aff3" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor1" "etiqueta" => "*" "correspondencia" => "Correspondence: Dra. S. Vidal Serrano. Justino de Neve, 5. 41004 Sevilla. España" ] ] ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "2004-08-24" "fechaAceptado" => "2005-01-06" "PalabrasClave" => array:2 [ "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Key Words" "identificador" => "xpalclavsec154128" "palabras" => array:3 [ 0 => "Sarcoidosis" 1 => "Radiographic stages" 2 => "Bronchoalveolar lavage" ] ] ] "es" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palabras clave" "identificador" => "xpalclavsec154129" "palabras" => array:3 [ 0 => "Sarcoidosis" 1 => "Estadios radiológicos" 2 => "Lavado broncoalveolar" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "en" => array:1 [ "resumen" => "<span class="elsevierStyleSectionTitle">Objective</span><p class="elsevierStyleSimplePara elsevierViewall">Sarcoidosis is a multisystem granulomatous inflammatory disease of unknown etiology that mainly affects the lungs and lymph nodes. Bronchoalveolar lavage (BAL) is known to be useful in diagnosis of the disease but its value as a prognostic marker is unclear. The aim of this study was to assess whether there is a characteristic pattern in BAL cell counts according to radiographic stage and determine whether BAL offers information on disease course.</p> <span class="elsevierStyleSectionTitle">Patients and methods</span><p class="elsevierStyleSimplePara elsevierViewall">The study included 34 patients with untreated sarcoidosis. Data were collected on the following variables: age, sex, smoking habit, treatment type, radiographic stage, respiratory function, serological parameters, and BAL cell counts. The patients were classified into 3 groups according to functional and radiographic change at 12-month follow-up.</p> <span class="elsevierStyleSectionTitle">Results</span><p class="elsevierStyleSimplePara elsevierViewall">NO differences in age, sex, or smoking habit were found according to either radiographic stage or disease course. Although the proportion of lymphocytes in BAL fluid was higher in radiographic stage I than in stages II and III, the differences were not statistically significant. The differences in BAL cell counts between groups based on disease course were not statistically significant.</p> <span class="elsevierStyleSectionTitle">Conclusions</span><p class="elsevierStyleSimplePara elsevierViewall">NO differences were found in the characteristics of BAL fluid according to radiographic stage. The differential cell count in BAL fluid does not appear to predict the course of sarcoidosis in the first 12 months.</p>" ] "es" => array:1 [ "resumen" => "<span class="elsevierStyleSectionTitle">Objetivo</span><p class="elsevierStyleSimplePara elsevierViewall">La sarcoidosis es una enfermedad inflamatoria granulomatosa multisistémica de causa desconocida que afecta principalmente al pulmón y a los ganglios linfáticos. La utilidad del lavado broncoalveolar (LBA) en el diagnósti-co es conocida, pero su valor como marcador pronóstico es controvertido. El objetivo de nuestro estudio es evaluar si existe un patrón característico en la celularidad del LBA según el estadio radiológico de presentación y determinar si el LBA aporta información sobre la evolución de la enfermedad.</p> <span class="elsevierStyleSectionTitle">Pacientes y métodos</span><p class="elsevierStyleSimplePara elsevierViewall">Se incluyó en el estudio a 34 pacientes con sarcoidosis no tratados. Se recogieron las siguientes variables: edad, sexo, hábito tabáquico, tipo de tratamiento, estadio radiológico, exploración funcional respiratoria, pará-metros serológicos y análisis celular del LBA. Se clasificó a los pacientes en 3 grupos según la evolución funcional y radioló-gica a los 12 meses.</p> <span class="elsevierStyleSectionTitle">Resultados</span><p class="elsevierStyleSimplePara elsevierViewall">NO se encontraron diferencias entre la edad, el sexo y el hábito tabáquico ni entre los estadios radiológicos ni entre los grupos según evolución. En el estadio radiológico I el recuento porcentual de linfocitos del LBA fue mayor que en los estadios II y III, pero las diferencias no fueron estadís-ticamente significativas. Las diferencias en el LBA por grupos evolutivos no fueron estadísticamente significativas.</p> <span class="elsevierStyleSectionTitle">Conclusiones</span><p class="elsevierStyleSimplePara elsevierViewall">Al analizar las características del LBA según estadios radiológicos no se encontraron diferencias. El recuento diferencial de células en el LBA no parece predecir el curso de la sarcoidosis durante los primeros 12 meses.</p>" ] ] "bibliografia" => array:2 [ "titulo" => "REFERENCES" "seccion" => array:1 [ 0 => array:1 [ "bibliografiaReferencia" => array:23 [ 0 => array:3 [ "identificador" => "bib1" "etiqueta" => "1" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Sarcoidosis" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "LS Newman" 1 => "CS Rose" 2 => "LA Maier" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1056/NEJM199704243361706" "Revista" => array:6 [ "tituloSerie" => "N Engl J Med" "fecha" => "1997" "volumen" => "336" "paginaInicial" => "1224" "paginaFinal" => "1234" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9110911" "web" => "Medline" ] ] ] ] ] ] ] ] 1 => array:3 [ "identificador" => "bib2" "etiqueta" => "2" "referencia" => array:1 [ 0 => 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| Year/Month | Html | Total | |
|---|---|---|---|
| 2024 November | 8 | 1 | 9 |
| 2024 October | 29 | 19 | 48 |
| 2024 September | 35 | 16 | 51 |
| 2024 August | 43 | 41 | 84 |
| 2024 July | 26 | 19 | 45 |
| 2024 June | 31 | 29 | 60 |
| 2024 May | 39 | 36 | 75 |
| 2024 April | 20 | 26 | 46 |
| 2024 March | 20 | 17 | 37 |
| 2024 February | 17 | 22 | 39 |
| 2023 March | 2 | 4 | 6 |
| 2023 February | 20 | 25 | 45 |
| 2023 January | 15 | 38 | 53 |
| 2022 December | 18 | 24 | 42 |
| 2022 November | 17 | 32 | 49 |
| 2022 October | 27 | 36 | 63 |
| 2022 September | 16 | 18 | 34 |
| 2022 August | 20 | 45 | 65 |
| 2022 July | 20 | 35 | 55 |
| 2022 June | 14 | 34 | 48 |
| 2022 May | 15 | 42 | 57 |
| 2022 April | 21 | 39 | 60 |
| 2022 March | 15 | 32 | 47 |
| 2022 February | 15 | 54 | 69 |
| 2022 January | 11 | 33 | 44 |
| 2021 December | 15 | 38 | 53 |
| 2021 November | 17 | 50 | 67 |
| 2021 October | 27 | 38 | 65 |
| 2021 September | 19 | 48 | 67 |
| 2021 August | 12 | 28 | 40 |
| 2021 July | 8 | 25 | 33 |
| 2021 June | 15 | 44 | 59 |
| 2021 May | 12 | 26 | 38 |
| 2021 April | 23 | 44 | 67 |
| 2021 March | 14 | 13 | 27 |
| 2021 February | 11 | 24 | 35 |
| 2021 January | 10 | 13 | 23 |
| 2020 December | 13 | 16 | 29 |
| 2020 November | 3 | 13 | 16 |
| 2020 October | 6 | 5 | 11 |
| 2020 September | 12 | 5 | 17 |
| 2020 August | 7 | 10 | 17 |
| 2020 July | 12 | 20 | 32 |
| 2020 June | 6 | 7 | 13 |
| 2020 May | 14 | 17 | 31 |
| 2020 April | 15 | 14 | 29 |
| 2020 March | 7 | 20 | 27 |
| 2020 February | 12 | 18 | 30 |
| 2020 January | 11 | 14 | 25 |
| 2019 December | 9 | 15 | 24 |
| 2019 November | 8 | 14 | 22 |
| 2019 October | 8 | 10 | 18 |
| 2019 September | 8 | 7 | 15 |
| 2019 August | 10 | 12 | 22 |
| 2019 July | 16 | 19 | 35 |
| 2019 June | 4 | 5 | 9 |
| 2019 May | 10 | 13 | 23 |
| 2019 April | 18 | 19 | 37 |
| 2019 March | 10 | 17 | 27 |
| 2019 February | 15 | 11 | 26 |
| 2019 January | 7 | 10 | 17 |
| 2018 December | 8 | 18 | 26 |
| 2018 November | 20 | 7 | 27 |
| 2018 October | 17 | 15 | 32 |
| 2018 September | 10 | 12 | 22 |
| 2018 May | 7 | 1 | 8 |
| 2018 April | 3 | 5 | 8 |
| 2018 March | 1 | 5 | 6 |
| 2018 February | 6 | 11 | 17 |
| 2018 January | 6 | 4 | 10 |
| 2017 December | 3 | 10 | 13 |
| 2017 November | 3 | 5 | 8 |
| 2017 October | 5 | 11 | 16 |
| 2017 September | 5 | 11 | 16 |
| 2017 August | 6 | 13 | 19 |
| 2017 July | 6 | 7 | 13 |
| 2017 June | 7 | 19 | 26 |
| 2017 May | 6 | 14 | 20 |
| 2017 April | 2 | 4 | 6 |
| 2017 March | 5 | 6 | 11 |
| 2017 February | 2 | 8 | 10 |
| 2017 January | 1 | 5 | 6 |
| 2016 December | 7 | 12 | 19 |
| 2016 November | 4 | 5 | 9 |
| 2016 October | 8 | 15 | 23 |
| 2016 September | 12 | 12 | 24 |
| 2016 August | 14 | 11 | 25 |
| 2016 July | 4 | 6 | 10 |
| 2016 March | 3 | 0 | 3 |
| 2016 February | 1 | 0 | 1 |
| 2015 December | 2 | 0 | 2 |
| 2015 October | 24 | 7 | 31 |
| 2015 September | 31 | 10 | 41 |
| 2015 August | 29 | 21 | 50 |
| 2015 July | 28 | 15 | 43 |
| 2015 June | 35 | 9 | 44 |
| 2015 May | 36 | 20 | 56 |
| 2015 April | 41 | 17 | 58 |
| 2015 March | 24 | 14 | 38 |
| 2015 February | 31 | 6 | 37 |
| 2015 January | 22 | 4 | 26 |
| 2014 December | 32 | 5 | 37 |
| 2014 November | 27 | 12 | 39 |
| 2014 October | 35 | 8 | 43 |
| 2014 September | 30 | 8 | 38 |
| 2014 August | 22 | 10 | 32 |
| 2014 July | 22 | 7 | 29 |
| 2014 June | 40 | 9 | 49 |
| 2014 May | 31 | 9 | 40 |
| 2014 April | 41 | 8 | 49 |
| 2014 March | 43 | 7 | 50 |
| 2014 February | 40 | 9 | 49 |
| 2014 January | 35 | 7 | 42 |
| 2013 December | 28 | 9 | 37 |
| 2013 November | 28 | 8 | 36 |
| 2013 October | 28 | 7 | 35 |
| 2013 September | 29 | 13 | 42 |
| 2013 August | 24 | 9 | 33 |
| 2013 July | 43 | 25 | 68 |
| 2013 June | 28 | 9 | 37 |
| 2013 May | 36 | 5 | 41 |
| 2013 April | 28 | 6 | 34 |
| 2013 March | 9 | 1 | 10 |
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