array:23 [
  "pii" => "S1579212906602425"
  "issn" => "15792129"
  "doi" => "10.1016/S1579-2129(06)60242-5"
  "estado" => "S300"
  "fechaPublicacion" => "2005-07-01"
  "aid" => "60242"
  "copyright" => "Sociedad Española de Neumología y Cirugía Torácica (SEPAR)"
  "copyrightAnyo" => "2005"
  "documento" => "article"
  "crossmark" => 0
  "subdocumento" => "fla"
  "cita" => "Arch Bronconeumol. 2005;41:363-70"
  "abierto" => array:3 [
    "ES" => false
    "ES2" => false
    "LATM" => false
  ]
  "gratuito" => false
  "lecturas" => array:2 [
    "total" => 1976
    "formatos" => array:3 [
      "EPUB" => 113
      "HTML" => 1264
      "PDF" => 599
    ]
  ]
  "itemSiguiente" => array:18 [
    "pii" => "S1579212906602437"
    "issn" => "15792129"
    "doi" => "10.1016/S1579-2129(06)60243-7"
    "estado" => "S300"
    "fechaPublicacion" => "2005-07-01"
    "aid" => "60243"
    "copyright" => "Sociedad Española de Neumología y Cirugía Torácica (SEPAR)"
    "documento" => "article"
    "crossmark" => 0
    "subdocumento" => "fla"
    "cita" => "Arch Bronconeumol. 2005;41:371-5"
    "abierto" => array:3 [
      "ES" => false
      "ES2" => false
      "LATM" => false
    ]
    "gratuito" => false
    "lecturas" => array:2 [
      "total" => 2261
      "formatos" => array:3 [
        "EPUB" => 107
        "HTML" => 1498
        "PDF" => 656
      ]
    ]
    "en" => array:10 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">Original Articles</span>"
      "titulo" => "Agreement in Asthmatics&#39; Perception of Dyspnea During Acute and Chronic Obstruction"
      "tienePdf" => "en"
      "tieneTextoCompleto" => 0
      "tieneResumen" => array:2 [
        0 => "en"
        1 => "es"
      ]
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "371"
          "paginaFinal" => "375"
        ]
      ]
      "contieneResumen" => array:2 [
        "en" => true
        "es" => true
      ]
      "contienePdf" => array:1 [
        "en" => true
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "E&#46; Mart&#237;nez-Morag&#243;n, M&#46; Perpi&#241;&#225;, A&#46; Belloch, A&#46; de Diego, M&#46;E&#46; Mart&#237;nez-Franc&#233;s"
          "autores" => array:5 [
            0 => array:3 [
              "preGrado" => "Dra&#46;"
              "nombre" => "E&#46;"
              "apellidos" => "Mart&#237;nez-Morag&#243;n"
            ]
            1 => array:2 [
              "nombre" => "M&#46;"
              "apellidos" => "Perpi&#241;&#225;"
            ]
            2 => array:2 [
              "nombre" => "A&#46;"
              "apellidos" => "Belloch"
            ]
            3 => array:2 [
              "nombre" => "A&#46;"
              "apellidos" => "de Diego"
            ]
            4 => array:2 [
              "nombre" => "M&#46;E&#46;"
              "apellidos" => "Mart&#237;nez-Franc&#233;s"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "en"
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1579212906602437?idApp=UINPBA00003Z"
    "url" => "/15792129/0000004100000007/v1_201305150220/S1579212906602437/v1_201305150220/en/main.assets"
  ]
  "itemAnterior" => array:18 [
    "pii" => "S1579212906602413"
    "issn" => "15792129"
    "doi" => "10.1016/S1579-2129(06)60241-3"
    "estado" => "S300"
    "fechaPublicacion" => "2005-07-01"
    "aid" => "60241"
    "copyright" => "Sociedad Espa&#241;ola de Neumolog&#237;a y Cirug&#237;a Tor&#225;cica &#40;SEPAR&#41;"
    "documento" => "simple-article"
    "crossmark" => 0
    "subdocumento" => "edi"
    "cita" => "Arch Bronconeumol. 2005;41:360-2"
    "abierto" => array:3 [
      "ES" => false
      "ES2" => false
      "LATM" => false
    ]
    "gratuito" => false
    "lecturas" => array:2 [
      "total" => 2388
      "formatos" => array:3 [
        "EPUB" => 90
        "HTML" => 1700
        "PDF" => 598
      ]
    ]
    "en" => array:8 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">Editorial</span>"
      "titulo" => "Women and Smoking&#58; Fatal Attraction"
      "tienePdf" => "en"
      "tieneTextoCompleto" => 0
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "360"
          "paginaFinal" => "362"
        ]
      ]
      "contienePdf" => array:1 [
        "en" => true
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "I&#46; Ner&#237;n"
          "autores" => array:1 [
            0 => array:3 [
              "preGrado" => "Dra&#46;"
              "nombre" => "I&#46;"
              "apellidos" => "Ner&#237;n"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "en"
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1579212906602413?idApp=UINPBA00003Z"
    "url" => "/15792129/0000004100000007/v1_201305150220/S1579212906602413/v1_201305150220/en/main.assets"
  ]
  "en" => array:15 [
    "idiomaDefecto" => true
    "cabecera" => "<span class="elsevierStyleTextfn">Original Articles</span>"
    "titulo" => "Effects of HIV Status and Other Variables on the Outcome of Tuberculosis Treatment in Spain"
    "tieneTextoCompleto" => 0
    "paginas" => array:1 [
      0 => array:2 [
        "paginaInicial" => "363"
        "paginaFinal" => "370"
      ]
    ]
    "autores" => array:1 [
      0 => array:4 [
        "autoresLista" => "M&#46; D&#237;ez Ruiz-Navarro, J&#46;A&#46; Hern&#225;ndez Espinosa, M&#46;J&#46; Bleda Hern&#225;ndez, A&#46; D&#237;az Franco, C&#46; Castells Carrillo, A&#46; Dom&#237;nguez Garc&#237;a, A&#46;M&#46; Garc&#237;a Fulgueiras, P&#46; Gayoso Diz, M&#46;J&#46; L&#243;pez de Valdivielso, M&#46;F&#46; V&#225;zquez Fern&#225;ndez"
        "autores" => array:11 [
          0 => array:5 [
            "preGrado" => "Dr&#46;"
            "nombre" => "M&#46;"
            "apellidos" => "D&#237;ez Ruiz-Navarro"
            "email" => array:1 [
              0 => "mdiez&#64;isciii&#46;es"
            ]
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">&#42;</span>"
                "identificador" => "cor1"
              ]
            ]
          ]
          1 => array:2 [
            "nombre" => "J&#46;A&#46;"
            "apellidos" => "Hern&#225;ndez Espinosa"
          ]
          2 => array:2 [
            "nombre" => "M&#46;J&#46;"
            "apellidos" => "Bleda Hern&#225;ndez"
          ]
          3 => array:2 [
            "nombre" => "A&#46;"
            "apellidos" => "D&#237;az Franco"
          ]
          4 => array:2 [
            "nombre" => "C&#46;"
            "apellidos" => "Castells Carrillo"
          ]
          5 => array:2 [
            "nombre" => "A&#46;"
            "apellidos" => "Dom&#237;nguez Garc&#237;a"
          ]
          6 => array:2 [
            "nombre" => "A&#46;M&#46;"
            "apellidos" => "Garc&#237;a Fulgueiras"
          ]
          7 => array:2 [
            "nombre" => "P&#46;"
            "apellidos" => "Gayoso Diz"
          ]
          8 => array:2 [
            "nombre" => "M&#46;J&#46;"
            "apellidos" => "L&#243;pez de Valdivielso"
          ]
          9 => array:2 [
            "nombre" => "M&#46;F&#46;"
            "apellidos" => "V&#225;zquez Fern&#225;ndez"
          ]
          10 => array:2 [
            "colaborador" => "on behalf of the PMIT-2 Working Group"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">&#42;</span>"
                "identificador" => "fn1"
              ]
            ]
          ]
        ]
        "afiliaciones" => array:1 [
          0 => array:1 [
            "entidad" => "Unidad de Investigaci&#243;n en Tuberculosis&#44; Centro Nacional de Epidemiolog&#237;a&#44; Instituto de Salud Carlos III&#44; Madrid&#44; Spain"
          ]
        ]
        "correspondencia" => array:1 [
          0 => array:3 [
            "identificador" => "cor1"
            "etiqueta" => "&#42;"
            "correspondencia" => "Correspondence&#58; Dr&#46; M&#46; D&#237;ez&#46; Unidad de Investigaci&#243;n en Tuberculosis&#46; Instituto de Salud Carlos III&#46; Sinesio Delgado&#44; 6&#46; 28029 Madrid&#46; Espa&#241;a"
          ]
        ]
      ]
    ]
    "pdfFichero" => "main.pdf"
    "tienePdf" => true
    "fechaRecibido" => "2004-07-08"
    "fechaAceptado" => "2005-01-18"
    "PalabrasClave" => array:2 [
      "en" => array:1 [
        0 => array:4 [
          "clase" => "keyword"
          "titulo" => "Key words"
          "identificador" => "xpalclavsec154102"
          "palabras" => array:3 [
            0 => "Outcome of tuberculosis treatment"
            1 => "Potentially unsatisfactory outcome"
            2 => "HIV status"
          ]
        ]
      ]
      "es" => array:1 [
        0 => array:4 [
          "clase" => "keyword"
          "titulo" => "Palabras clave"
          "identificador" => "xpalclavsec154103"
          "palabras" => array:3 [
            0 => "Resultados del tratamiento antituberculoso"
            1 => "Resultado potencialmente insatisfactorio"
            2 => "Estado VIH"
          ]
        ]
      ]
    ]
    "tieneResumen" => true
    "resumen" => array:2 [
      "en" => array:1 [
        "resumen" => "<span class="elsevierStyleSectionTitle">Objective</span><p class="elsevierStyleSimplePara elsevierViewall">TO analyze the effect of human immunodeficiency virus &#40;HIV&#41; status and other variables on the outcome of tuberculosis treatment in Spain&#46;</p> <span class="elsevierStyleSectionTitle">Patients and methods</span><p class="elsevierStyleSimplePara elsevierViewall">Multicenter retrospective cohort study in 6 autonomous communities of Spain &#40;from May 1996 to April 1997&#41;&#46; Data on treatment outcome were collected for new cases of tuberculosis in accordance with European guidelines&#46; Follow up of patients continued for 3 months after scheduled end of treatment&#46;</p> <span class="elsevierStyleSectionTitle">Results</span><p class="elsevierStyleSimplePara elsevierViewall">Of the 4899 patients included&#44; 3417 &#40;69&#46;7&#37;&#41; had a satisfactory outcome&#44; 438 &#40;8&#46;9&#37;&#41; died before or during treatment&#44; and 1044 &#40;21&#46;4&#37;&#41; had a potentially unsatisfactory outcome&#46; On stratification by HIV status&#44; satisfactory outcome&#44; mortality&#44; and potentially unsatisfactory outcome were reported for 43&#46;4&#37;&#44; 21&#46;5&#37;&#44; and 35&#46;1&#37;&#44; respectively&#44; of HIV-positive patients&#59; 71&#37;&#44; 6&#46;2&#37;&#44; and 22&#46;8&#37;&#44; respectively&#44; of HIV-negative patients&#59; and 74&#46;3&#37;&#44; 7&#46;5&#37;&#44; and 18&#46;2&#37;&#44; respectively&#44; of patients with no HIV status available&#46; HIV modified the effect of several variables on the outcome of treatment&#44; and so separate logistic regression models for each HIV category were constructed&#46; Among HIV-positive patients&#44; mortality increased in patients with neoplastic disease and in users of drugs by nonintravenous routes of administration&#44; whereas potentially unsatisfactory outcomes increased in intravenous drug users and in women&#46;</p> <span class="elsevierStyleSectionTitle">Conclusions</span><p class="elsevierStyleSimplePara elsevierViewall">In Spain&#44; the outcome of tuberculosis treatment is much worse in HIV-positive patients&#46; Drug use and presence of neoplastic disease substantially affect mortality&#46;</p>"
      ]
      "es" => array:1 [
        "resumen" => "<span class="elsevierStyleSectionTitle">Objetivo</span><p class="elsevierStyleSimplePara elsevierViewall">Analizar el efecto del virus de la inmunodeficiencia humana &#40;VIH&#41; y otras variables sobre el resultado del tratamiento antituberculoso en Espa&#241;a&#46;</p> <span class="elsevierStyleSectionTitle">Pacientes y m&#233;todos</span><p class="elsevierStyleSimplePara elsevierViewall">Estudio multic&#233;ntrico de cohorte retrospectivo en 6 comunidades aut&#243;nomas &#40;de mayo de 1996 a abril de 1997&#41;&#46; Se recogi&#243; informaci&#243;n sobre el resultado del tratamiento en casos nuevos de tuberculosis siguiendo la normativa europea&#46; Se realiz&#243; seguimiento de los casos hasta 3 meses despu&#233;s de la fecha prevista de finalizaci&#243;n del tratamiento&#46;</p> <span class="elsevierStyleSectionTitle">Resultados</span><p class="elsevierStyleSimplePara elsevierViewall">De los 4&#46;899 pacientes incluidos&#44; se observ&#243; un resultado satisfactorio en 3&#46;417 &#40;69&#44;7&#37;&#41;&#44; 438 &#40;8&#44;9&#37;&#41; murieron antes o durante el tratamiento y 1&#46;044 &#40;21&#44;4&#37;&#41; tuvieron un resultado potencialmente insatisfactorio&#46; Estratificando por el estado de la infecci&#243;n por el VIH&#44; las cifras fueron&#44; respectivamente&#58; para los que la presentaban&#44; del 43&#44;4&#44; el 21&#44;5 y el 35&#44;1&#37;&#59; para los seronegativos&#44; del 71&#44; el 6&#44;2 y el 22&#44;8&#37;&#44; y para aquellos en quienes no constaba&#44; del 74&#44;3&#44; el 7&#44;5 y el 18&#44;2&#37;&#46; El VIH modificaba el efecto de diversas variables sobre el resultado del tratamiento&#44; por lo que se ajustaron modelos de regresi&#243;n log&#237;stica separados para cada categor&#237;a VIH&#46; Entre los seropositivos&#44; la mortalidad aument&#243; en enfermos con neoplasias y en usuarios de drogas por v&#237;as distintas de la parenteral&#44; mientras que los resultados potencialmente insatisfactorios aumentaron en usuarios de drogas por v&#237;a intravenosa y en las mujeres&#46;</p> <span class="elsevierStyleSectionTitle">Conclusiones</span><p class="elsevierStyleSimplePara elsevierViewall">En Espa&#241;a&#44; el resultado del tratamiento antituberculoso es mucho peor en enfermos infectados por el VIH&#46; El uso de drogas y el hecho de padecer neoplasias tienen un papel importante sobre la mortalidad&#46;</p>"
      ]
    ]
    "NotaPie" => array:1 [
      0 => array:2 [
        "etiqueta" => "&#42;"
        "nota" => "<p class="elsevierStyleNotepara">The members of the PMIT-2 working group are listed at the end of the article&#46; This work received financial support from the Fondo de Investigaci&#243;n Sanitaria &#40;Health Resarch Fund&#41;&#44; project no&#46; 99&#47;0016&#46;</p>"
      ]
    ]
    "bibliografia" => array:2 [
      "titulo" => "REFERENCES"
      "seccion" => array:1 [
        0 => array:1 [
          "bibliografiaReferencia" => array:32 [
            0 => array:3 [
              "identificador" => "bib1"
              "etiqueta" => "1"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:1 [
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "World Health Organization"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "LibroEditado" => array:3 [
                        "titulo" => "WHO Tuberculosis Program&#58; Framework for effective tuberculosis control"
                        "paginaInicial" => "179"
                        "serieFecha" => "1994"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            1 => array:3 [
              "identificador" => "bib2"
              "etiqueta" => "2"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Standardised tuberculosis treatment outcome monitoring in Europe&#8212;Recommendations of a Working Group of the World Health Organization and the European Region of the International Union Against Tuberculosis and Lung Disease &#40;IUATLD&#41; for uniform reporting by cohort analysis of treatment outcome in tuberculosis patients"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:5 [
                            0 => "J Veen"
                            1 => "M Raviglione"
                            2 => "H Rieder"
                            3 => "G Migliori"
                            4 => "P Graf"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Eur Respir J"
                        "fecha" => "1998"
                        "volumen" => "12"
                        "paginaInicial" => "505"
                        "paginaFinal" => "510"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9727811"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            2 => array:3 [
              "identificador" => "bib3"
              "etiqueta" => "3"
              "referencia" => array:1 [
                0 => array:1 [
                  "referenciaCompleta" => "EuroTB &#40;INVS&#47;KNCV&#41; and the national coordinators for tuberculosis surveillance in the WHO European Region&#46; Surveillance of tuberculosis in Europe&#46; Report on tuberculosis case notified in 2001&#46; 2003&#46; p&#46; 1-120&#46;"
                ]
              ]
            ]
            3 => array:3 [
              "identificador" => "bib4"
              "etiqueta" => "4"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:1 [
                      "autores" => array:1 [
                        0 => array:2 [
                          "colaboracion" => "European Centre for the Epidemiological Monitoring of AIDS"
                          "etal" => false
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Libro" => array:4 [
                        "titulo" => "HIV&#47;AIDS surveillance in Europe&#46; Mid-year report 2002"
                        "fecha" => "2002"
                        "editorial" => "Institut de Veille Sanitaire"
                        "editorialLocalizacion" => "Saint-Maurice"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            4 => array:3 [
              "identificador" => "bib5"
              "etiqueta" => "5"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Descenso de la incidencia de tuberculosis siguiendo la introducci&#243;n de los nuevos tratamientos frente al VIH"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "J Castilla Catal&#225;n"
                            1 => "L Guerra Romero"
                            2 => "J Ca&#241;&#243;n Campos"
                            3 => "I Noguer Zambrano"
                            4 => "F Parras V&#225;zquez"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Rev Clin Esp"
                        "fecha" => "1999"
                        "volumen" => "199"
                        "paginaInicial" => "76"
                        "paginaFinal" => "77"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            5 => array:3 [
              "identificador" => "bib6"
              "etiqueta" => "6"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Tuberculosis in Spain&#58; epidemiological pattern and clinical practice"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "M D&#237;ez"
                            1 => "C Huerta"
                            2 => "T Moreno"
                            3 => "T Caloto"
                            4 => "D Guerra"
                            5 => "F Pozo"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Int J Tuberc Lung Dis"
                        "fecha" => "2002"
                        "volumen" => "6"
                        "paginaInicial" => "295"
                        "paginaFinal" => "300"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11936737"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            6 => array:3 [
              "identificador" => "bib7"
              "etiqueta" => "7"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "The spread of AIDS and the re-emergence of tuberculosis in Catalonia&#44; Spain"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "M Vall Mayans"
                            1 => "A Maguire"
                            2 => "M Miret"
                            3 => "J Alcaide"
                            4 => "I Parron"
                            5 => "J Casabona"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "AIDS"
                        "fecha" => "1997"
                        "volumen" => "1"
                        "paginaInicial" => "499"
                        "paginaFinal" => "505"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            7 => array:3 [
              "identificador" => "bib8"
              "etiqueta" => "8"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Resultados del tratamiento antituberculoso en seis comunidades aut&#243;nomas espa&#241;olas"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "M D&#237;ez Ruiz-Navarro"
                            1 => "J Hern&#225;ndez Espinosa"
                            2 => "T Caloto Gonz&#225;lez"
                            3 => "C Castells Carillo"
                            4 => "A Dom&#237;nguez Garc&#237;a"
                            5 => "A Garc&#237;a Fulgueiras"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Med Clin &#40;Barc&#41;"
                        "fecha" => "2001"
                        "volumen" => "117"
                        "paginaInicial" => "474"
                        "paginaFinal" => "480"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            8 => array:3 [
              "identificador" => "bib9"
              "etiqueta" => "9"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:1 [
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "D Hosmer"
                            1 => "A Lemeshow"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Libro" => array:5 [
                        "edicion" => "2nd edition"
                        "titulo" => "Applied logistic regression"
                        "fecha" => "2000"
                        "editorial" => "Wiley-Intersciencie"
                        "editorialLocalizacion" => "New York"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            9 => array:3 [
              "identificador" => "bib10"
              "etiqueta" => "10"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:1 [
                      "autores" => array:1 [
                        0 => array:2 [
                          "colaboracion" => "StataCorp"
                          "etal" => false
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Libro" => array:4 [
                        "titulo" => "Stata Statistical Software&#58; Release 6&#46;0"
                        "fecha" => "1999"
                        "editorial" => "Stata Corporation"
                        "editorialLocalizacion" => "College Station&#44; TX"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            10 => array:3 [
              "identificador" => "bib11"
              "etiqueta" => "11"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Outcome of patients treated for tuberculosis in Vaud County&#44; Switzerland"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "J Zellweger"
                            1 => "P Coulon"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:7 [
                        "tituloSerie" => "Int J Tuberc Lung Dis"
                        "fecha" => "1998"
                        "volumen" => "2"
                        "numero" => "5"
                        "paginaInicial" => "372"
                        "paginaFinal" => "377"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9613632"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            11 => array:3 [
              "identificador" => "bib12"
              "etiqueta" => "12"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:1 [
                      "autores" => array:1 [
                        0 => array:2 [
                          "colaboracion" => "Grupo de Trabajo del PMIT&#47;Grupo de trabajo del PMETA"
                          "etal" => false
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Libro" => array:4 [
                        "titulo" => "La tuberculosis en Andaluc&#237;a&#46; Resultados de los Proyectos Multic&#233;ntricos PMITA-PMETA"
                        "fecha" => "2000"
                        "editorial" => "Junta de Andaluc&#237;a&#44; Consejer&#237;a de Salud"
                        "editorialLocalizacion" => "Seville"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            12 => array:3 [
              "identificador" => "bib13"
              "etiqueta" => "13"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Factors predicting non-completion of tuberculosis treatment among HIV-infected patients in Barcelona &#40;1987-1996&#41;"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "H Gald&#243;s Tang&#252;is"
                            1 => "J Cayl&#225;"
                            2 => "P Garc&#237;a de Olalla"
                            3 => "J Jans&#225;"
                            4 => "T Brugal"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:7 [
                        "tituloSerie" => "Int J Tuberc Lung Dis"
                        "fecha" => "2000"
                        "volumen" => "4"
                        "numero" => "1"
                        "paginaInicial" => "55"
                        "paginaFinal" => "60"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10654645"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            13 => array:3 [
              "identificador" => "bib14"
              "etiqueta" => "14"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Resultados del tratamiento de la tuberculosis inicial en el &#225;rea sur de Sevilla en un per&#237;odo de 5 a&#241;os &#40;1994-1998&#41;"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "F Campos Rodr&#237;guez"
                            1 => "F Mu&#241;oz Lucena"
                            2 => "S Umbr&#237;a Dom&#237;nguez"
                            3 => "C M&#233;ndez"
                            4 => "M Nogales P&#233;rez"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Arch Bronconeumol"
                        "fecha" => "2001"
                        "volumen" => "37"
                        "paginaInicial" => "177"
                        "paginaFinal" => "183"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11412502"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            14 => array:3 [
              "identificador" => "bib15"
              "etiqueta" => "15"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Follow-up of tuberculosis cases diagnosed in Galicia&#44; Spain in 1995"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "M Blanco-Aparicio"
                            1 => "E Fern&#225;ndez"
                            2 => "L Anibarro"
                            3 => "E V&#225;zquez"
                            4 => "R Lema"
                            5 => "A Penas"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Int J Tuberc Lung Dis"
                        "fecha" => "1997"
                        "volumen" => "1"
                        "numero" => "5"
                        "paginaInicial" => "S73"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            15 => array:3 [
              "identificador" => "bib16"
              "etiqueta" => "16"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Six-month supervised intermittent tuberculosis therapy in Haitian patients with and without HIV infection"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "R Chaisson"
                            1 => "H Clermont"
                            2 => "E Holt"
                            3 => "M Cantave"
                            4 => "M Johnson"
                            5 => "J Atkinson"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1164/ajrccm.154.4.8887603"
                      "Revista" => array:7 [
                        "tituloSerie" => "Am J Respir Crit Care Med"
                        "fecha" => "1996"
                        "volumen" => "154"
                        "paginaInicial" => "1034"
                        "paginaFinal" => "1038"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8887603"
                            "web" => "Medline"
                          ]
                        ]
                        "itemHostRev" => array:3 [
                          "pii" => "S0034935610701912"
                          "estado" => "S300"
                          "issn" => "00349356"
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            16 => array:3 [
              "identificador" => "bib17"
              "etiqueta" => "17"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Human immunodeficiency virus and the outcome of treatment for new and recurrent pulmonary tuberculosis in African patients"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "J Murray"
                            1 => "P Sonnenberg"
                            2 => "C Stuart"
                            3 => "C Shearer"
                            4 => "P Godfrey-Faussett"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1164/ajrccm.159.3.9804147"
                      "Revista" => array:7 [
                        "tituloSerie" => "Am J Respir Crit Care Med"
                        "fecha" => "1999"
                        "volumen" => "159"
                        "numero" => "3"
                        "paginaInicial" => "733"
                        "paginaFinal" => "740"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10051244"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            17 => array:3 [
              "identificador" => "bib18"
              "etiqueta" => "18"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Outcome of pulmonary tuberculosis treatment in the tertiary care setting-Toronto 1992&#47;93&#46; Tuberculosis Treatment Completion Study Group"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "W Wobeser"
                            1 => "L Yuan"
                            2 => "M Naus"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "CMAJ"
                        "fecha" => "1999"
                        "volumen" => "160"
                        "paginaInicial" => "789"
                        "paginaFinal" => "794"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10189422"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            18 => array:3 [
              "identificador" => "bib19"
              "etiqueta" => "19"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "DOTS-based tuberculosis treatment and control during civil conflict and an HIV epidemic&#44; Churachandpur District&#44; India"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "A Rodger"
                            1 => "M Toole"
                            2 => "B Lalnuntluangi"
                            3 => "V Muana"
                            4 => "P Deutschmann"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Bull WHO"
                        "fecha" => "2002"
                        "volumen" => "80"
                        "paginaInicial" => "451"
                        "paginaFinal" => "456"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12132001"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            19 => array:3 [
              "identificador" => "bib20"
              "etiqueta" => "20"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "A review of efficacy studies of a 6-month short-course therapy for tuberculosis among patients infected with human immunodeficiency virus&#58; differences in study outcomes"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "W el-Sadr"
                            1 => "D Perlman"
                            2 => "E Denning"
                            3 => "J Matts"
                            4 => "D Cohn"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1086/318706"
                      "Revista" => array:7 [
                        "tituloSerie" => "Clin Infect Dis"
                        "fecha" => "2001"
                        "volumen" => "32"
                        "numero" => "4"
                        "paginaInicial" => "623"
                        "paginaFinal" => "632"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11181127"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            20 => array:3 [
              "identificador" => "bib21"
              "etiqueta" => "21"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Fondo de Investigaci&#243;n Sanitaria&#46; Consenso Nacional para el Control de la Tuberculosis en Espa&#241;a"
                      "autores" => array:1 [
                        0 => array:2 [
                          "colaboracion" => "Ministerio de Sanidad y Consumo"
                          "etal" => false
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Med Clin &#40;Barc&#41;"
                        "fecha" => "1992"
                        "volumen" => "98"
                        "paginaInicial" => "24"
                        "paginaFinal" => "31"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            21 => array:3 [
              "identificador" => "bib22"
              "etiqueta" => "22"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:1 [
                      "autores" => array:1 [
                        0 => array:2 [
                          "colaboracion" => "WHO"
                          "etal" => false
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Libro" => array:4 [
                        "titulo" => "Global Tuberculosis Programme&#46; Anti-tuberculosis drug resistance in the world&#46; The WHO&#47;IUATLD Global project on anti-tuberculosis drug resistance surveillance 1994-1997"
                        "fecha" => "1997"
                        "editorial" => "WHO"
                        "editorialLocalizacion" => "Geneva"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            22 => array:3 [
              "identificador" => "bib23"
              "etiqueta" => "23"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Farmacorresistencia de <span class="elsevierStyleItalic">Mycobacterium tuberculosis&#46;</span> Estudio multic&#233;ntrico en el &#225;rea de Barcelona"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "N Mart&#237;n-Casabona"
                            1 => "F Alcaide"
                            2 => "P Coll"
                            3 => "J Gonz&#225;lez"
                            4 => "J Manterola"
                            5 => "M Sald&#243;"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Med Clin &#40;Barc&#41;"
                        "fecha" => "2000"
                        "volumen" => "115"
                        "paginaInicial" => "493"
                        "paginaFinal" => "581"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            23 => array:3 [
              "identificador" => "bib24"
              "etiqueta" => "24"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Resistencias de <span class="elsevierStyleItalic">Mycobacterium tuberculosis</span> en Zaragoza &#40;1993-1997&#41; y factores asociados"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "L Torres"
                            1 => "P Arazo"
                            2 => "J Blas P&#233;rez"
                            3 => "MP Amador"
                            4 => "MA Lezcano"
                            5 => "MJ Revillo"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Med Clin &#40;Barc&#41;"
                        "fecha" => "2000"
                        "volumen" => "115"
                        "paginaInicial" => "605"
                        "paginaFinal" => "609"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            24 => array:3 [
              "identificador" => "bib25"
              "etiqueta" => "25"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Occurrence of tuberculosis and latent tuberculosis infection among HIV-positive subjects in Spain"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "M D&#237;ez"
                            1 => "M Bleda"
                            2 => "M Camafort"
                            3 => "C Cepeda"
                            4 => "A Costa"
                            5 => "O Ferrero"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Int J Tuberc Lung Dis"
                        "fecha" => "2002"
                        "volumen" => "6"
                        "numero" => "Suppl 1"
                        "paginaInicial" => "90"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            25 => array:3 [
              "identificador" => "bib26"
              "etiqueta" => "26"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Factors influencing HIV progression in a seroconverter cohort in Madrid from 1985 to 1999"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "J del Amo"
                            1 => "J del Romero"
                            2 => "A Barrasa"
                            3 => "S P&#233;rez-Hoyos"
                            4 => "C Rodr&#237;guez"
                            5 => "M D&#237;ez"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Sex Transm Infect"
                        "fecha" => "2002"
                        "volumen" => "78"
                        "paginaInicial" => "255"
                        "paginaFinal" => "260"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12181462"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            26 => array:3 [
              "identificador" => "bib27"
              "etiqueta" => "27"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Effectiveness of highly active antiretroviral therapy in Spanish cohorts of HIV seroconverters&#58; differences by transmission category"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "S P&#233;rez-Hoyos"
                            1 => "J del Amo"
                            2 => "R Muga"
                            3 => "J del Romero"
                            4 => "P Garc&#237;a de Olalla"
                            5 => "R Guerrero"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1097/01.aids.0000042940.55529.93"
                      "Revista" => array:6 [
                        "tituloSerie" => "AIDS"
                        "fecha" => "2003"
                        "volumen" => "17"
                        "paginaInicial" => "1"
                        "paginaFinal" => "7"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12478064"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            27 => array:3 [
              "identificador" => "bib28"
              "etiqueta" => "28"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Effectiveness of supervised&#44; intermittent therapy for tuberculosis in HIV-infected patients"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "K Alwood"
                            1 => "J Keruly"
                            2 => "K Moore-Rice"
                            3 => "D Stanton"
                            4 => "C Chaulk"
                            5 => "R Chaisson"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "AIDS"
                        "fecha" => "1994"
                        "volumen" => "8"
                        "paginaInicial" => "1103"
                        "paginaFinal" => "1108"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/7986406"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            28 => array:3 [
              "identificador" => "bib29"
              "etiqueta" => "29"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Tuberculosis prevention in methadone maintenance clinics&#46; Effectiveness and cost-effectiveness"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "D Snyder"
                            1 => "E Paz"
                            2 => "J Mohle-Boetani"
                            3 => "R Fallstad"
                            4 => "R Black"
                            5 => "D Chin"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1164/ajrccm.160.1.9810082"
                      "Revista" => array:7 [
                        "tituloSerie" => "Am J Respir Crit Care Med"
                        "fecha" => "1999"
                        "volumen" => "160"
                        "numero" => "1"
                        "paginaInicial" => "178"
                        "paginaFinal" => "185"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10390397"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            29 => array:3 [
              "identificador" => "bib30"
              "etiqueta" => "30"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Predictors of adherence to tuberculosis treatment in a supervised therapy programme for prisoners before and after release&#46; Study Group of Adherence to Tuberculosis Treatment of Prisoners"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "A Marco"
                            1 => "J Cayl&#224;"
                            2 => "M Serra"
                            3 => "R Pedro"
                            4 => "C Sanrama"
                            5 => "R Guerrero"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Eur Respir J"
                        "fecha" => "1998"
                        "volumen" => "12"
                        "paginaInicial" => "967"
                        "paginaFinal" => "971"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9817177"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            30 => array:3 [
              "identificador" => "bib31"
              "etiqueta" => "31"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Infections with Mycobacterium tuberculosis and <span class="elsevierStyleItalic">Mycobacterium avium</span> among HIV-infected patients after the introduction of highly active antiretroviral therapy&#46; EuroSIDA Study Group JD"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "O Kirk"
                            1 => "J Gatell"
                            2 => "A Mocroft"
                            3 => "C Pedersen"
                            4 => "R Proenca"
                            5 => "R Brettle"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1164/ajrccm.162.3.9908018"
                      "Revista" => array:6 [
                        "tituloSerie" => "Am J Respir Crit Care Med"
                        "fecha" => "2000"
                        "volumen" => "162"
                        "paginaInicial" => "865"
                        "paginaFinal" => "872"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10988097"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            31 => array:3 [
              "identificador" => "bib32"
              "etiqueta" => "32"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Treatment of tuberculosis in HIV-infected persons in the era of highly active antiretroviral therapy"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "G Dean"
                            1 => "S Edwards"
                            2 => "N Ives"
                            3 => "G Matthews"
                            4 => "E Fox"
                            5 => "L Navaratne"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "AIDS"
                        "fecha" => "2002"
                        "volumen" => "16"
                        "paginaInicial" => "75"
                        "paginaFinal" => "83"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11741165"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
          ]
        ]
      ]
    ]
  ]
  "idiomaDefecto" => "en"
  "url" => "/15792129/0000004100000007/v1_201305150220/S1579212906602425/v1_201305150220/en/main.assets"
  "Apartado" => null
  "PDF" => "https://static.elsevier.es/multimedia/15792129/0000004100000007/v1_201305150220/S1579212906602425/v1_201305150220/en/main.pdf?idApp=UINPBA00003Z&text.app=https://archbronconeumol.org/"
  "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1579212906602425?idApp=UINPBA00003Z"
]
Share
Journal Information

Statistics

Follow this link to access the full text of the article

Original Articles
Effects of HIV Status and Other Variables on the Outcome of Tuberculosis Treatment in Spain
M. Díez Ruiz-Navarro
Corresponding author
mdiez@isciii.es

Correspondence: Dr. M. Díez. Unidad de Investigación en Tuberculosis. Instituto de Salud Carlos III. Sinesio Delgado, 6. 28029 Madrid. España
, J.A. Hernández Espinosa, M.J. Bleda Hernández, A. Díaz Franco, C. Castells Carrillo, A. Domínguez García, A.M. García Fulgueiras, P. Gayoso Diz, M.J. López de Valdivielso, M.F. Vázquez Fernández, on behalf of the PMIT-2 Working Group *
Unidad de Investigación en Tuberculosis, Centro Nacional de Epidemiología, Instituto de Salud Carlos III, Madrid, Spain
Read
3802
Times
was read the article
1789
Total PDF
2013
Total HTML
Share statistics
 array:23 [
  "pii" => "S1579212906602425"
  "issn" => "15792129"
  "doi" => "10.1016/S1579-2129(06)60242-5"
  "estado" => "S300"
  "fechaPublicacion" => "2005-07-01"
  "aid" => "60242"
  "copyright" => "Sociedad Espa&#241;ola de Neumolog&#237;a y Cirug&#237;a Tor&#225;cica &#40;SEPAR&#41;"
  "copyrightAnyo" => "2005"
  "documento" => "article"
  "crossmark" => 0
  "subdocumento" => "fla"
  "cita" => "Arch Bronconeumol. 2005;41:363-70"
  "abierto" => array:3 [
    "ES" => false
    "ES2" => false
    "LATM" => false
  ]
  "gratuito" => false
  "lecturas" => array:2 [
    "total" => 1976
    "formatos" => array:3 [
      "EPUB" => 113
      "HTML" => 1264
      "PDF" => 599
    ]
  ]
  "itemSiguiente" => array:18 [
    "pii" => "S1579212906602437"
    "issn" => "15792129"
    "doi" => "10.1016/S1579-2129(06)60243-7"
    "estado" => "S300"
    "fechaPublicacion" => "2005-07-01"
    "aid" => "60243"
    "copyright" => "Sociedad Espa&#241;ola de Neumolog&#237;a y Cirug&#237;a Tor&#225;cica &#40;SEPAR&#41;"
    "documento" => "article"
    "crossmark" => 0
    "subdocumento" => "fla"
    "cita" => "Arch Bronconeumol. 2005;41:371-5"
    "abierto" => array:3 [
      "ES" => false
      "ES2" => false
      "LATM" => false
    ]
    "gratuito" => false
    "lecturas" => array:2 [
      "total" => 2261
      "formatos" => array:3 [
        "EPUB" => 107
        "HTML" => 1498
        "PDF" => 656
      ]
    ]
    "en" => array:10 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">Original Articles</span>"
      "titulo" => "Agreement in Asthmatics&#39; Perception of Dyspnea During Acute and Chronic Obstruction"
      "tienePdf" => "en"
      "tieneTextoCompleto" => 0
      "tieneResumen" => array:2 [
        0 => "en"
        1 => "es"
      ]
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "371"
          "paginaFinal" => "375"
        ]
      ]
      "contieneResumen" => array:2 [
        "en" => true
        "es" => true
      ]
      "contienePdf" => array:1 [
        "en" => true
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "E&#46; Mart&#237;nez-Morag&#243;n, M&#46; Perpi&#241;&#225;, A&#46; Belloch, A&#46; de Diego, M&#46;E&#46; Mart&#237;nez-Franc&#233;s"
          "autores" => array:5 [
            0 => array:3 [
              "preGrado" => "Dra&#46;"
              "nombre" => "E&#46;"
              "apellidos" => "Mart&#237;nez-Morag&#243;n"
            ]
            1 => array:2 [
              "nombre" => "M&#46;"
              "apellidos" => "Perpi&#241;&#225;"
            ]
            2 => array:2 [
              "nombre" => "A&#46;"
              "apellidos" => "Belloch"
            ]
            3 => array:2 [
              "nombre" => "A&#46;"
              "apellidos" => "de Diego"
            ]
            4 => array:2 [
              "nombre" => "M&#46;E&#46;"
              "apellidos" => "Mart&#237;nez-Franc&#233;s"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "en"
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1579212906602437?idApp=UINPBA00003Z"
    "url" => "/15792129/0000004100000007/v1_201305150220/S1579212906602437/v1_201305150220/en/main.assets"
  ]
  "itemAnterior" => array:18 [
    "pii" => "S1579212906602413"
    "issn" => "15792129"
    "doi" => "10.1016/S1579-2129(06)60241-3"
    "estado" => "S300"
    "fechaPublicacion" => "2005-07-01"
    "aid" => "60241"
    "copyright" => "Sociedad Espa&#241;ola de Neumolog&#237;a y Cirug&#237;a Tor&#225;cica &#40;SEPAR&#41;"
    "documento" => "simple-article"
    "crossmark" => 0
    "subdocumento" => "edi"
    "cita" => "Arch Bronconeumol. 2005;41:360-2"
    "abierto" => array:3 [
      "ES" => false
      "ES2" => false
      "LATM" => false
    ]
    "gratuito" => false
    "lecturas" => array:2 [
      "total" => 2388
      "formatos" => array:3 [
        "EPUB" => 90
        "HTML" => 1700
        "PDF" => 598
      ]
    ]
    "en" => array:8 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">Editorial</span>"
      "titulo" => "Women and Smoking&#58; Fatal Attraction"
      "tienePdf" => "en"
      "tieneTextoCompleto" => 0
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "360"
          "paginaFinal" => "362"
        ]
      ]
      "contienePdf" => array:1 [
        "en" => true
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "I&#46; Ner&#237;n"
          "autores" => array:1 [
            0 => array:3 [
              "preGrado" => "Dra&#46;"
              "nombre" => "I&#46;"
              "apellidos" => "Ner&#237;n"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "en"
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1579212906602413?idApp=UINPBA00003Z"
    "url" => "/15792129/0000004100000007/v1_201305150220/S1579212906602413/v1_201305150220/en/main.assets"
  ]
  "en" => array:15 [
    "idiomaDefecto" => true
    "cabecera" => "<span class="elsevierStyleTextfn">Original Articles</span>"
    "titulo" => "Effects of HIV Status and Other Variables on the Outcome of Tuberculosis Treatment in Spain"
    "tieneTextoCompleto" => 0
    "paginas" => array:1 [
      0 => array:2 [
        "paginaInicial" => "363"
        "paginaFinal" => "370"
      ]
    ]
    "autores" => array:1 [
      0 => array:4 [
        "autoresLista" => "M&#46; D&#237;ez Ruiz-Navarro, J&#46;A&#46; Hern&#225;ndez Espinosa, M&#46;J&#46; Bleda Hern&#225;ndez, A&#46; D&#237;az Franco, C&#46; Castells Carrillo, A&#46; Dom&#237;nguez Garc&#237;a, A&#46;M&#46; Garc&#237;a Fulgueiras, P&#46; Gayoso Diz, M&#46;J&#46; L&#243;pez de Valdivielso, M&#46;F&#46; V&#225;zquez Fern&#225;ndez"
        "autores" => array:11 [
          0 => array:5 [
            "preGrado" => "Dr&#46;"
            "nombre" => "M&#46;"
            "apellidos" => "D&#237;ez Ruiz-Navarro"
            "email" => array:1 [
              0 => "mdiez&#64;isciii&#46;es"
            ]
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">&#42;</span>"
                "identificador" => "cor1"
              ]
            ]
          ]
          1 => array:2 [
            "nombre" => "J&#46;A&#46;"
            "apellidos" => "Hern&#225;ndez Espinosa"
          ]
          2 => array:2 [
            "nombre" => "M&#46;J&#46;"
            "apellidos" => "Bleda Hern&#225;ndez"
          ]
          3 => array:2 [
            "nombre" => "A&#46;"
            "apellidos" => "D&#237;az Franco"
          ]
          4 => array:2 [
            "nombre" => "C&#46;"
            "apellidos" => "Castells Carrillo"
          ]
          5 => array:2 [
            "nombre" => "A&#46;"
            "apellidos" => "Dom&#237;nguez Garc&#237;a"
          ]
          6 => array:2 [
            "nombre" => "A&#46;M&#46;"
            "apellidos" => "Garc&#237;a Fulgueiras"
          ]
          7 => array:2 [
            "nombre" => "P&#46;"
            "apellidos" => "Gayoso Diz"
          ]
          8 => array:2 [
            "nombre" => "M&#46;J&#46;"
            "apellidos" => "L&#243;pez de Valdivielso"
          ]
          9 => array:2 [
            "nombre" => "M&#46;F&#46;"
            "apellidos" => "V&#225;zquez Fern&#225;ndez"
          ]
          10 => array:2 [
            "colaborador" => "on behalf of the PMIT-2 Working Group"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">&#42;</span>"
                "identificador" => "fn1"
              ]
            ]
          ]
        ]
        "afiliaciones" => array:1 [
          0 => array:1 [
            "entidad" => "Unidad de Investigaci&#243;n en Tuberculosis&#44; Centro Nacional de Epidemiolog&#237;a&#44; Instituto de Salud Carlos III&#44; Madrid&#44; Spain"
          ]
        ]
        "correspondencia" => array:1 [
          0 => array:3 [
            "identificador" => "cor1"
            "etiqueta" => "&#42;"
            "correspondencia" => "Correspondence&#58; Dr&#46; M&#46; D&#237;ez&#46; Unidad de Investigaci&#243;n en Tuberculosis&#46; Instituto de Salud Carlos III&#46; Sinesio Delgado&#44; 6&#46; 28029 Madrid&#46; Espa&#241;a"
          ]
        ]
      ]
    ]
    "pdfFichero" => "main.pdf"
    "tienePdf" => true
    "fechaRecibido" => "2004-07-08"
    "fechaAceptado" => "2005-01-18"
    "PalabrasClave" => array:2 [
      "en" => array:1 [
        0 => array:4 [
          "clase" => "keyword"
          "titulo" => "Key words"
          "identificador" => "xpalclavsec154102"
          "palabras" => array:3 [
            0 => "Outcome of tuberculosis treatment"
            1 => "Potentially unsatisfactory outcome"
            2 => "HIV status"
          ]
        ]
      ]
      "es" => array:1 [
        0 => array:4 [
          "clase" => "keyword"
          "titulo" => "Palabras clave"
          "identificador" => "xpalclavsec154103"
          "palabras" => array:3 [
            0 => "Resultados del tratamiento antituberculoso"
            1 => "Resultado potencialmente insatisfactorio"
            2 => "Estado VIH"
          ]
        ]
      ]
    ]
    "tieneResumen" => true
    "resumen" => array:2 [
      "en" => array:1 [
        "resumen" => "<span class="elsevierStyleSectionTitle">Objective</span><p class="elsevierStyleSimplePara elsevierViewall">TO analyze the effect of human immunodeficiency virus &#40;HIV&#41; status and other variables on the outcome of tuberculosis treatment in Spain&#46;</p> <span class="elsevierStyleSectionTitle">Patients and methods</span><p class="elsevierStyleSimplePara elsevierViewall">Multicenter retrospective cohort study in 6 autonomous communities of Spain &#40;from May 1996 to April 1997&#41;&#46; Data on treatment outcome were collected for new cases of tuberculosis in accordance with European guidelines&#46; Follow up of patients continued for 3 months after scheduled end of treatment&#46;</p> <span class="elsevierStyleSectionTitle">Results</span><p class="elsevierStyleSimplePara elsevierViewall">Of the 4899 patients included&#44; 3417 &#40;69&#46;7&#37;&#41; had a satisfactory outcome&#44; 438 &#40;8&#46;9&#37;&#41; died before or during treatment&#44; and 1044 &#40;21&#46;4&#37;&#41; had a potentially unsatisfactory outcome&#46; On stratification by HIV status&#44; satisfactory outcome&#44; mortality&#44; and potentially unsatisfactory outcome were reported for 43&#46;4&#37;&#44; 21&#46;5&#37;&#44; and 35&#46;1&#37;&#44; respectively&#44; of HIV-positive patients&#59; 71&#37;&#44; 6&#46;2&#37;&#44; and 22&#46;8&#37;&#44; respectively&#44; of HIV-negative patients&#59; and 74&#46;3&#37;&#44; 7&#46;5&#37;&#44; and 18&#46;2&#37;&#44; respectively&#44; of patients with no HIV status available&#46; HIV modified the effect of several variables on the outcome of treatment&#44; and so separate logistic regression models for each HIV category were constructed&#46; Among HIV-positive patients&#44; mortality increased in patients with neoplastic disease and in users of drugs by nonintravenous routes of administration&#44; whereas potentially unsatisfactory outcomes increased in intravenous drug users and in women&#46;</p> <span class="elsevierStyleSectionTitle">Conclusions</span><p class="elsevierStyleSimplePara elsevierViewall">In Spain&#44; the outcome of tuberculosis treatment is much worse in HIV-positive patients&#46; Drug use and presence of neoplastic disease substantially affect mortality&#46;</p>"
      ]
      "es" => array:1 [
        "resumen" => "<span class="elsevierStyleSectionTitle">Objetivo</span><p class="elsevierStyleSimplePara elsevierViewall">Analizar el efecto del virus de la inmunodeficiencia humana &#40;VIH&#41; y otras variables sobre el resultado del tratamiento antituberculoso en Espa&#241;a&#46;</p> <span class="elsevierStyleSectionTitle">Pacientes y m&#233;todos</span><p class="elsevierStyleSimplePara elsevierViewall">Estudio multic&#233;ntrico de cohorte retrospectivo en 6 comunidades aut&#243;nomas &#40;de mayo de 1996 a abril de 1997&#41;&#46; Se recogi&#243; informaci&#243;n sobre el resultado del tratamiento en casos nuevos de tuberculosis siguiendo la normativa europea&#46; Se realiz&#243; seguimiento de los casos hasta 3 meses despu&#233;s de la fecha prevista de finalizaci&#243;n del tratamiento&#46;</p> <span class="elsevierStyleSectionTitle">Resultados</span><p class="elsevierStyleSimplePara elsevierViewall">De los 4&#46;899 pacientes incluidos&#44; se observ&#243; un resultado satisfactorio en 3&#46;417 &#40;69&#44;7&#37;&#41;&#44; 438 &#40;8&#44;9&#37;&#41; murieron antes o durante el tratamiento y 1&#46;044 &#40;21&#44;4&#37;&#41; tuvieron un resultado potencialmente insatisfactorio&#46; Estratificando por el estado de la infecci&#243;n por el VIH&#44; las cifras fueron&#44; respectivamente&#58; para los que la presentaban&#44; del 43&#44;4&#44; el 21&#44;5 y el 35&#44;1&#37;&#59; para los seronegativos&#44; del 71&#44; el 6&#44;2 y el 22&#44;8&#37;&#44; y para aquellos en quienes no constaba&#44; del 74&#44;3&#44; el 7&#44;5 y el 18&#44;2&#37;&#46; El VIH modificaba el efecto de diversas variables sobre el resultado del tratamiento&#44; por lo que se ajustaron modelos de regresi&#243;n log&#237;stica separados para cada categor&#237;a VIH&#46; Entre los seropositivos&#44; la mortalidad aument&#243; en enfermos con neoplasias y en usuarios de drogas por v&#237;as distintas de la parenteral&#44; mientras que los resultados potencialmente insatisfactorios aumentaron en usuarios de drogas por v&#237;a intravenosa y en las mujeres&#46;</p> <span class="elsevierStyleSectionTitle">Conclusiones</span><p class="elsevierStyleSimplePara elsevierViewall">En Espa&#241;a&#44; el resultado del tratamiento antituberculoso es mucho peor en enfermos infectados por el VIH&#46; El uso de drogas y el hecho de padecer neoplasias tienen un papel importante sobre la mortalidad&#46;</p>"
      ]
    ]
    "NotaPie" => array:1 [
      0 => array:2 [
        "etiqueta" => "&#42;"
        "nota" => "<p class="elsevierStyleNotepara">The members of the PMIT-2 working group are listed at the end of the article&#46; This work received financial support from the Fondo de Investigaci&#243;n Sanitaria &#40;Health Resarch Fund&#41;&#44; project no&#46; 99&#47;0016&#46;</p>"
      ]
    ]
    "bibliografia" => array:2 [
      "titulo" => "REFERENCES"
      "seccion" => array:1 [
        0 => array:1 [
          "bibliografiaReferencia" => array:32 [
            0 => array:3 [
              "identificador" => "bib1"
              "etiqueta" => "1"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:1 [
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "World Health Organization"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "LibroEditado" => array:3 [
                        "titulo" => "WHO Tuberculosis Program&#58; Framework for effective tuberculosis control"
                        "paginaInicial" => "179"
                        "serieFecha" => "1994"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            1 => array:3 [
              "identificador" => "bib2"
              "etiqueta" => "2"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Standardised tuberculosis treatment outcome monitoring in Europe&#8212;Recommendations of a Working Group of the World Health Organization and the European Region of the International Union Against Tuberculosis and Lung Disease &#40;IUATLD&#41; for uniform reporting by cohort analysis of treatment outcome in tuberculosis patients"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:5 [
                            0 => "J Veen"
                            1 => "M Raviglione"
                            2 => "H Rieder"
                            3 => "G Migliori"
                            4 => "P Graf"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Eur Respir J"
                        "fecha" => "1998"
                        "volumen" => "12"
                        "paginaInicial" => "505"
                        "paginaFinal" => "510"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9727811"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            2 => array:3 [
              "identificador" => "bib3"
              "etiqueta" => "3"
              "referencia" => array:1 [
                0 => array:1 [
                  "referenciaCompleta" => "EuroTB &#40;INVS&#47;KNCV&#41; and the national coordinators for tuberculosis surveillance in the WHO European Region&#46; Surveillance of tuberculosis in Europe&#46; Report on tuberculosis case notified in 2001&#46; 2003&#46; p&#46; 1-120&#46;"
                ]
              ]
            ]
            3 => array:3 [
              "identificador" => "bib4"
              "etiqueta" => "4"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:1 [
                      "autores" => array:1 [
                        0 => array:2 [
                          "colaboracion" => "European Centre for the Epidemiological Monitoring of AIDS"
                          "etal" => false
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Libro" => array:4 [
                        "titulo" => "HIV&#47;AIDS surveillance in Europe&#46; Mid-year report 2002"
                        "fecha" => "2002"
                        "editorial" => "Institut de Veille Sanitaire"
                        "editorialLocalizacion" => "Saint-Maurice"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            4 => array:3 [
              "identificador" => "bib5"
              "etiqueta" => "5"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Descenso de la incidencia de tuberculosis siguiendo la introducci&#243;n de los nuevos tratamientos frente al VIH"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "J Castilla Catal&#225;n"
                            1 => "L Guerra Romero"
                            2 => "J Ca&#241;&#243;n Campos"
                            3 => "I Noguer Zambrano"
                            4 => "F Parras V&#225;zquez"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Rev Clin Esp"
                        "fecha" => "1999"
                        "volumen" => "199"
                        "paginaInicial" => "76"
                        "paginaFinal" => "77"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            5 => array:3 [
              "identificador" => "bib6"
              "etiqueta" => "6"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Tuberculosis in Spain&#58; epidemiological pattern and clinical practice"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "M D&#237;ez"
                            1 => "C Huerta"
                            2 => "T Moreno"
                            3 => "T Caloto"
                            4 => "D Guerra"
                            5 => "F Pozo"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Int J Tuberc Lung Dis"
                        "fecha" => "2002"
                        "volumen" => "6"
                        "paginaInicial" => "295"
                        "paginaFinal" => "300"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11936737"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            6 => array:3 [
              "identificador" => "bib7"
              "etiqueta" => "7"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "The spread of AIDS and the re-emergence of tuberculosis in Catalonia&#44; Spain"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "M Vall Mayans"
                            1 => "A Maguire"
                            2 => "M Miret"
                            3 => "J Alcaide"
                            4 => "I Parron"
                            5 => "J Casabona"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "AIDS"
                        "fecha" => "1997"
                        "volumen" => "1"
                        "paginaInicial" => "499"
                        "paginaFinal" => "505"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            7 => array:3 [
              "identificador" => "bib8"
              "etiqueta" => "8"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Resultados del tratamiento antituberculoso en seis comunidades aut&#243;nomas espa&#241;olas"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "M D&#237;ez Ruiz-Navarro"
                            1 => "J Hern&#225;ndez Espinosa"
                            2 => "T Caloto Gonz&#225;lez"
                            3 => "C Castells Carillo"
                            4 => "A Dom&#237;nguez Garc&#237;a"
                            5 => "A Garc&#237;a Fulgueiras"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Med Clin &#40;Barc&#41;"
                        "fecha" => "2001"
                        "volumen" => "117"
                        "paginaInicial" => "474"
                        "paginaFinal" => "480"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            8 => array:3 [
              "identificador" => "bib9"
              "etiqueta" => "9"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:1 [
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "D Hosmer"
                            1 => "A Lemeshow"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Libro" => array:5 [
                        "edicion" => "2nd edition"
                        "titulo" => "Applied logistic regression"
                        "fecha" => "2000"
                        "editorial" => "Wiley-Intersciencie"
                        "editorialLocalizacion" => "New York"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            9 => array:3 [
              "identificador" => "bib10"
              "etiqueta" => "10"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:1 [
                      "autores" => array:1 [
                        0 => array:2 [
                          "colaboracion" => "StataCorp"
                          "etal" => false
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Libro" => array:4 [
                        "titulo" => "Stata Statistical Software&#58; Release 6&#46;0"
                        "fecha" => "1999"
                        "editorial" => "Stata Corporation"
                        "editorialLocalizacion" => "College Station&#44; TX"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            10 => array:3 [
              "identificador" => "bib11"
              "etiqueta" => "11"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Outcome of patients treated for tuberculosis in Vaud County&#44; Switzerland"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "J Zellweger"
                            1 => "P Coulon"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:7 [
                        "tituloSerie" => "Int J Tuberc Lung Dis"
                        "fecha" => "1998"
                        "volumen" => "2"
                        "numero" => "5"
                        "paginaInicial" => "372"
                        "paginaFinal" => "377"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9613632"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            11 => array:3 [
              "identificador" => "bib12"
              "etiqueta" => "12"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:1 [
                      "autores" => array:1 [
                        0 => array:2 [
                          "colaboracion" => "Grupo de Trabajo del PMIT&#47;Grupo de trabajo del PMETA"
                          "etal" => false
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Libro" => array:4 [
                        "titulo" => "La tuberculosis en Andaluc&#237;a&#46; Resultados de los Proyectos Multic&#233;ntricos PMITA-PMETA"
                        "fecha" => "2000"
                        "editorial" => "Junta de Andaluc&#237;a&#44; Consejer&#237;a de Salud"
                        "editorialLocalizacion" => "Seville"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            12 => array:3 [
              "identificador" => "bib13"
              "etiqueta" => "13"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Factors predicting non-completion of tuberculosis treatment among HIV-infected patients in Barcelona &#40;1987-1996&#41;"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "H Gald&#243;s Tang&#252;is"
                            1 => "J Cayl&#225;"
                            2 => "P Garc&#237;a de Olalla"
                            3 => "J Jans&#225;"
                            4 => "T Brugal"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:7 [
                        "tituloSerie" => "Int J Tuberc Lung Dis"
                        "fecha" => "2000"
                        "volumen" => "4"
                        "numero" => "1"
                        "paginaInicial" => "55"
                        "paginaFinal" => "60"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10654645"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            13 => array:3 [
              "identificador" => "bib14"
              "etiqueta" => "14"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Resultados del tratamiento de la tuberculosis inicial en el &#225;rea sur de Sevilla en un per&#237;odo de 5 a&#241;os &#40;1994-1998&#41;"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "F Campos Rodr&#237;guez"
                            1 => "F Mu&#241;oz Lucena"
                            2 => "S Umbr&#237;a Dom&#237;nguez"
                            3 => "C M&#233;ndez"
                            4 => "M Nogales P&#233;rez"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Arch Bronconeumol"
                        "fecha" => "2001"
                        "volumen" => "37"
                        "paginaInicial" => "177"
                        "paginaFinal" => "183"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11412502"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            14 => array:3 [
              "identificador" => "bib15"
              "etiqueta" => "15"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Follow-up of tuberculosis cases diagnosed in Galicia&#44; Spain in 1995"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "M Blanco-Aparicio"
                            1 => "E Fern&#225;ndez"
                            2 => "L Anibarro"
                            3 => "E V&#225;zquez"
                            4 => "R Lema"
                            5 => "A Penas"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Int J Tuberc Lung Dis"
                        "fecha" => "1997"
                        "volumen" => "1"
                        "numero" => "5"
                        "paginaInicial" => "S73"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            15 => array:3 [
              "identificador" => "bib16"
              "etiqueta" => "16"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Six-month supervised intermittent tuberculosis therapy in Haitian patients with and without HIV infection"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "R Chaisson"
                            1 => "H Clermont"
                            2 => "E Holt"
                            3 => "M Cantave"
                            4 => "M Johnson"
                            5 => "J Atkinson"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1164/ajrccm.154.4.8887603"
                      "Revista" => array:7 [
                        "tituloSerie" => "Am J Respir Crit Care Med"
                        "fecha" => "1996"
                        "volumen" => "154"
                        "paginaInicial" => "1034"
                        "paginaFinal" => "1038"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8887603"
                            "web" => "Medline"
                          ]
                        ]
                        "itemHostRev" => array:3 [
                          "pii" => "S0034935610701912"
                          "estado" => "S300"
                          "issn" => "00349356"
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            16 => array:3 [
              "identificador" => "bib17"
              "etiqueta" => "17"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Human immunodeficiency virus and the outcome of treatment for new and recurrent pulmonary tuberculosis in African patients"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "J Murray"
                            1 => "P Sonnenberg"
                            2 => "C Stuart"
                            3 => "C Shearer"
                            4 => "P Godfrey-Faussett"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1164/ajrccm.159.3.9804147"
                      "Revista" => array:7 [
                        "tituloSerie" => "Am J Respir Crit Care Med"
                        "fecha" => "1999"
                        "volumen" => "159"
                        "numero" => "3"
                        "paginaInicial" => "733"
                        "paginaFinal" => "740"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10051244"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            17 => array:3 [
              "identificador" => "bib18"
              "etiqueta" => "18"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Outcome of pulmonary tuberculosis treatment in the tertiary care setting-Toronto 1992&#47;93&#46; Tuberculosis Treatment Completion Study Group"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "W Wobeser"
                            1 => "L Yuan"
                            2 => "M Naus"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "CMAJ"
                        "fecha" => "1999"
                        "volumen" => "160"
                        "paginaInicial" => "789"
                        "paginaFinal" => "794"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10189422"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            18 => array:3 [
              "identificador" => "bib19"
              "etiqueta" => "19"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "DOTS-based tuberculosis treatment and control during civil conflict and an HIV epidemic&#44; Churachandpur District&#44; India"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "A Rodger"
                            1 => "M Toole"
                            2 => "B Lalnuntluangi"
                            3 => "V Muana"
                            4 => "P Deutschmann"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Bull WHO"
                        "fecha" => "2002"
                        "volumen" => "80"
                        "paginaInicial" => "451"
                        "paginaFinal" => "456"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12132001"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            19 => array:3 [
              "identificador" => "bib20"
              "etiqueta" => "20"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "A review of efficacy studies of a 6-month short-course therapy for tuberculosis among patients infected with human immunodeficiency virus&#58; differences in study outcomes"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "W el-Sadr"
                            1 => "D Perlman"
                            2 => "E Denning"
                            3 => "J Matts"
                            4 => "D Cohn"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1086/318706"
                      "Revista" => array:7 [
                        "tituloSerie" => "Clin Infect Dis"
                        "fecha" => "2001"
                        "volumen" => "32"
                        "numero" => "4"
                        "paginaInicial" => "623"
                        "paginaFinal" => "632"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11181127"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            20 => array:3 [
              "identificador" => "bib21"
              "etiqueta" => "21"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Fondo de Investigaci&#243;n Sanitaria&#46; Consenso Nacional para el Control de la Tuberculosis en Espa&#241;a"
                      "autores" => array:1 [
                        0 => array:2 [
                          "colaboracion" => "Ministerio de Sanidad y Consumo"
                          "etal" => false
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Med Clin &#40;Barc&#41;"
                        "fecha" => "1992"
                        "volumen" => "98"
                        "paginaInicial" => "24"
                        "paginaFinal" => "31"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            21 => array:3 [
              "identificador" => "bib22"
              "etiqueta" => "22"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:1 [
                      "autores" => array:1 [
                        0 => array:2 [
                          "colaboracion" => "WHO"
                          "etal" => false
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Libro" => array:4 [
                        "titulo" => "Global Tuberculosis Programme&#46; Anti-tuberculosis drug resistance in the world&#46; The WHO&#47;IUATLD Global project on anti-tuberculosis drug resistance surveillance 1994-1997"
                        "fecha" => "1997"
                        "editorial" => "WHO"
                        "editorialLocalizacion" => "Geneva"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            22 => array:3 [
              "identificador" => "bib23"
              "etiqueta" => "23"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Farmacorresistencia de <span class="elsevierStyleItalic">Mycobacterium tuberculosis&#46;</span> Estudio multic&#233;ntrico en el &#225;rea de Barcelona"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "N Mart&#237;n-Casabona"
                            1 => "F Alcaide"
                            2 => "P Coll"
                            3 => "J Gonz&#225;lez"
                            4 => "J Manterola"
                            5 => "M Sald&#243;"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Med Clin &#40;Barc&#41;"
                        "fecha" => "2000"
                        "volumen" => "115"
                        "paginaInicial" => "493"
                        "paginaFinal" => "581"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            23 => array:3 [
              "identificador" => "bib24"
              "etiqueta" => "24"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Resistencias de <span class="elsevierStyleItalic">Mycobacterium tuberculosis</span> en Zaragoza &#40;1993-1997&#41; y factores asociados"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "L Torres"
                            1 => "P Arazo"
                            2 => "J Blas P&#233;rez"
                            3 => "MP Amador"
                            4 => "MA Lezcano"
                            5 => "MJ Revillo"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Med Clin &#40;Barc&#41;"
                        "fecha" => "2000"
                        "volumen" => "115"
                        "paginaInicial" => "605"
                        "paginaFinal" => "609"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            24 => array:3 [
              "identificador" => "bib25"
              "etiqueta" => "25"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Occurrence of tuberculosis and latent tuberculosis infection among HIV-positive subjects in Spain"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "M D&#237;ez"
                            1 => "M Bleda"
                            2 => "M Camafort"
                            3 => "C Cepeda"
                            4 => "A Costa"
                            5 => "O Ferrero"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Int J Tuberc Lung Dis"
                        "fecha" => "2002"
                        "volumen" => "6"
                        "numero" => "Suppl 1"
                        "paginaInicial" => "90"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            25 => array:3 [
              "identificador" => "bib26"
              "etiqueta" => "26"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Factors influencing HIV progression in a seroconverter cohort in Madrid from 1985 to 1999"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "J del Amo"
                            1 => "J del Romero"
                            2 => "A Barrasa"
                            3 => "S P&#233;rez-Hoyos"
                            4 => "C Rodr&#237;guez"
                            5 => "M D&#237;ez"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Sex Transm Infect"
                        "fecha" => "2002"
                        "volumen" => "78"
                        "paginaInicial" => "255"
                        "paginaFinal" => "260"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12181462"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            26 => array:3 [
              "identificador" => "bib27"
              "etiqueta" => "27"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Effectiveness of highly active antiretroviral therapy in Spanish cohorts of HIV seroconverters&#58; differences by transmission category"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "S P&#233;rez-Hoyos"
                            1 => "J del Amo"
                            2 => "R Muga"
                            3 => "J del Romero"
                            4 => "P Garc&#237;a de Olalla"
                            5 => "R Guerrero"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1097/01.aids.0000042940.55529.93"
                      "Revista" => array:6 [
                        "tituloSerie" => "AIDS"
                        "fecha" => "2003"
                        "volumen" => "17"
                        "paginaInicial" => "1"
                        "paginaFinal" => "7"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12478064"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            27 => array:3 [
              "identificador" => "bib28"
              "etiqueta" => "28"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Effectiveness of supervised&#44; intermittent therapy for tuberculosis in HIV-infected patients"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "K Alwood"
                            1 => "J Keruly"
                            2 => "K Moore-Rice"
                            3 => "D Stanton"
                            4 => "C Chaulk"
                            5 => "R Chaisson"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "AIDS"
                        "fecha" => "1994"
                        "volumen" => "8"
                        "paginaInicial" => "1103"
                        "paginaFinal" => "1108"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/7986406"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            28 => array:3 [
              "identificador" => "bib29"
              "etiqueta" => "29"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Tuberculosis prevention in methadone maintenance clinics&#46; Effectiveness and cost-effectiveness"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "D Snyder"
                            1 => "E Paz"
                            2 => "J Mohle-Boetani"
                            3 => "R Fallstad"
                            4 => "R Black"
                            5 => "D Chin"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1164/ajrccm.160.1.9810082"
                      "Revista" => array:7 [
                        "tituloSerie" => "Am J Respir Crit Care Med"
                        "fecha" => "1999"
                        "volumen" => "160"
                        "numero" => "1"
                        "paginaInicial" => "178"
                        "paginaFinal" => "185"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10390397"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            29 => array:3 [
              "identificador" => "bib30"
              "etiqueta" => "30"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Predictors of adherence to tuberculosis treatment in a supervised therapy programme for prisoners before and after release&#46; Study Group of Adherence to Tuberculosis Treatment of Prisoners"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "A Marco"
                            1 => "J Cayl&#224;"
                            2 => "M Serra"
                            3 => "R Pedro"
                            4 => "C Sanrama"
                            5 => "R Guerrero"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Eur Respir J"
                        "fecha" => "1998"
                        "volumen" => "12"
                        "paginaInicial" => "967"
                        "paginaFinal" => "971"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9817177"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            30 => array:3 [
              "identificador" => "bib31"
              "etiqueta" => "31"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Infections with Mycobacterium tuberculosis and <span class="elsevierStyleItalic">Mycobacterium avium</span> among HIV-infected patients after the introduction of highly active antiretroviral therapy&#46; EuroSIDA Study Group JD"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "O Kirk"
                            1 => "J Gatell"
                            2 => "A Mocroft"
                            3 => "C Pedersen"
                            4 => "R Proenca"
                            5 => "R Brettle"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1164/ajrccm.162.3.9908018"
                      "Revista" => array:6 [
                        "tituloSerie" => "Am J Respir Crit Care Med"
                        "fecha" => "2000"
                        "volumen" => "162"
                        "paginaInicial" => "865"
                        "paginaFinal" => "872"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10988097"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            31 => array:3 [
              "identificador" => "bib32"
              "etiqueta" => "32"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Treatment of tuberculosis in HIV-infected persons in the era of highly active antiretroviral therapy"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "G Dean"
                            1 => "S Edwards"
                            2 => "N Ives"
                            3 => "G Matthews"
                            4 => "E Fox"
                            5 => "L Navaratne"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "AIDS"
                        "fecha" => "2002"
                        "volumen" => "16"
                        "paginaInicial" => "75"
                        "paginaFinal" => "83"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11741165"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
          ]
        ]
      ]
    ]
  ]
  "idiomaDefecto" => "en"
  "url" => "/15792129/0000004100000007/v1_201305150220/S1579212906602425/v1_201305150220/en/main.assets"
  "Apartado" => null
  "PDF" => "https://static.elsevier.es/multimedia/15792129/0000004100000007/v1_201305150220/S1579212906602425/v1_201305150220/en/main.pdf?idApp=UINPBA00003Z&text.app=https://archbronconeumol.org/"
  "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1579212906602425?idApp=UINPBA00003Z"
]
Article information
ISSN: 15792129
Original language: English
The statistics are updated each day
Year/Month Html Pdf Total
2024 November 2 3 5
2024 October 33 25 58
2024 September 34 10 44
2024 August 41 38 79
2024 July 22 17 39
2024 June 24 52 76
2024 May 34 25 59
2024 April 17 27 44
2024 March 18 17 35
2024 February 17 21 38
2023 March 1 6 7
2023 February 14 21 35
2023 January 19 28 47
2022 December 16 21 37
2022 November 15 22 37
2022 October 20 27 47
2022 September 14 25 39
2022 August 15 32 47
2022 July 17 39 56
2022 June 14 31 45
2022 May 17 36 53
2022 April 13 31 44
2022 March 16 33 49
2022 February 22 43 65
2022 January 12 35 47
2021 December 16 46 62
2021 November 16 42 58
2021 October 19 40 59
2021 September 16 47 63
2021 August 6 25 31
2021 July 15 27 42
2021 June 17 35 52
2021 May 8 31 39
2021 April 22 42 64
2021 March 27 26 53
2021 February 8 21 29
2021 January 6 9 15
2020 December 13 13 26
2020 November 11 18 29
2020 October 9 7 16
2020 September 6 8 14
2020 August 10 12 22
2020 July 11 17 28
2020 June 3 6 9
2020 May 19 17 36
2020 April 11 12 23
2020 March 9 17 26
2020 February 13 18 31
2020 January 17 10 27
2019 December 14 16 30
2019 November 16 19 35
2019 October 8 6 14
2019 September 3 4 7
2019 August 14 12 26
2019 July 9 14 23
2019 June 5 4 9
2019 May 6 10 16
2019 April 11 9 20
2019 March 11 16 27
2019 February 11 16 27
2019 January 6 4 10
2018 December 11 17 28
2018 November 18 12 30
2018 October 13 11 24
2018 September 9 9 18
2018 May 1 2 3
2018 April 10 9 19
2018 March 1 4 5
2018 February 7 10 17
2018 January 9 10 19
2017 December 5 5 10
2017 November 5 4 9
2017 October 8 9 17
2017 September 5 11 16
2017 August 7 10 17
2017 July 5 4 9
2017 June 7 13 20
2017 May 7 14 21
2017 April 2 4 6
2017 March 2 24 26
2017 February 3 5 8
2017 January 3 3 6
2016 December 8 8 16
2016 November 12 7 19
2016 October 11 14 25
2016 September 7 10 17
2016 August 6 4 10
2016 July 3 5 8
2016 March 1 0 1
2016 February 1 0 1
2015 December 2 0 2
2015 October 52 1 53
2015 September 49 4 53
2015 August 38 7 45
2015 July 31 6 37
2015 June 30 2 32
2015 May 39 8 47
2015 April 27 9 36
2015 March 24 6 30
2015 February 23 3 26
2015 January 30 5 35
2014 December 22 2 24
2014 November 18 5 23
2014 October 27 9 36
2014 September 24 8 32
2014 August 23 8 31
2014 July 26 6 32
2014 June 34 16 50
2014 May 37 10 47
2014 April 32 8 40
2014 March 46 9 55
2014 February 41 6 47
2014 January 26 8 34
2013 December 28 6 34
2013 November 24 9 33
2013 October 20 5 25
2013 September 29 9 38
2013 August 22 13 35
2013 July 38 8 46
2013 June 22 4 26
2013 May 28 4 32
2013 April 19 5 24
2013 March 6 1 7
Show all

Follow this link to access the full text of the article

Archivos de Bronconeumología

Are you a health professional able to prescribe or dispense drugs?