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Vol. 60. Issue 5.
Pages 269-278 (May 2024)
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Vol. 60. Issue 5.
Pages 269-278 (May 2024)
Original Article
N-acetylcysteine Treatment in Chronic Obstructive Pulmonary Disease (COPD) and Chronic Bronchitis/Pre-COPD: Distinct Meta-analyses
Alberto Papia,
Corresponding author
ppa@unife.it

Corresponding author.
, Franco Alfanoa, Tommaso Bigonia, Lorenzo Mancinib, Amal Mawassb, Federico Baraldia, Cristina Aljamac, Marco Contolia, Marc Miravitllesc
a Department of Translational Medicine, University of Ferrara Medical School, University of Ferrara, Sant’Anna University Hospital, Ferrara, Italy
b Alira Health S.r.l., 20121 Milan, Italy
c Pneumology Department, Hospital Universitari Vall d’Hebron, Vall d’Hebron Institut de Recerca (VHIR), Barcelona, Spain
Highlights

  • Treatment effects on PROs in chronic bronchitis (CB) with/out COPD are scarcely known.

  • N-acetylcysteine (NAC) improve symptoms and/or QoL in studies conducted in CB.

  • NAC reduce exacerbations in studies conducted in subjects with CB.

  • Similarly, NAC reduce exacerbations and improve symptoms and/or QoL in COPD studies.

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Original Article
N-acetylcysteine Treatment in Chronic Obstructive Pulmonary Disease (COPD) and Chronic Bronchitis/Pre-COPD: Distinct Meta-analyses
Alberto Papia,
Corresponding author
ppa@unife.it

Corresponding author.
, Franco Alfanoa, Tommaso Bigonia, Lorenzo Mancinib, Amal Mawassb, Federico Baraldia, Cristina Aljamac, Marco Contolia, Marc Miravitllesc
a Department of Translational Medicine, University of Ferrara Medical School, University of Ferrara, Sant’Anna University Hospital, Ferrara, Italy
b Alira Health S.r.l., 20121 Milan, Italy
c Pneumology Department, Hospital Universitari Vall d’Hebron, Vall d’Hebron Institut de Recerca (VHIR), Barcelona, Spain
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Article information
ISSN: 03002896
Original language: English
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2024 May 175 67 242
2024 April 191 83 274
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