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    "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">A 56-year-old non-smoker man presented to the outpatient clinic with a chief complaint of dysgraphia&#46; Magnetic resonance imaging of the brain revealed a 62-mm mass in the left occipital lobe&#44; and brain biopsy revealed metastatic lung cancer harboring a rearrangement in the anaplastic lymphoma kinase &#40;ALK&#41; gene&#46; Five days after initiating first-line chemotherapy with alectinib&#44; the patient complained of a dry cough&#46; Chest computed tomography showed bilateral scattered ground-glass opacities with thickening of the interlobular septa &#40;<a class="elsevierStyleCrossRef" href="#fig0005">Fig&#46; 1</a>A&#8211;C&#41;&#46; Bronchoalveolar lavage of the right upper lobe retrieved a bloody fluid with a gradual increase in concentration &#40;<a class="elsevierStyleCrossRef" href="#fig0005">Fig&#46; 1</a>D&#41;&#44; and cytology revealed hemosiderin-laden macrophages &#40;<a class="elsevierStyleCrossRef" href="#fig0005">Fig&#46; 1</a>E&#41;&#46; We diagnosed the patient with alectinib-induced diffuse alveolar hemorrhage &#40;DAH&#41;&#46;<a class="elsevierStyleCrossRef" href="#bib0015"><span class="elsevierStyleSup">1</span></a> The patient&#39;s condition rapidly improved after discontinuation of alectinib and initiation of systemic steroid therapy&#46; Lorlatinib was safely administered as the second-line chemotherapy without DAH&#46; ALK-inhibitor induced DAH has not been previously reported&#46; In this case&#44; age was the only risk factor for interstitial lung disease associated with ALK inhibitors&#46;<a class="elsevierStyleCrossRef" href="#bib0020"><span class="elsevierStyleSup">2</span></a> In central lung cancer&#44; promptly performing a bronchoscopy aids the treatment strategy because airway obstruction due to bleeding can be critical &#40;<a class="elsevierStyleCrossRef" href="#fig0005">Fig&#46; 1</a>F&#41;&#46; The patient provided informed consent for the publication this article&#46;</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0005">Funding</span><p id="par0010" class="elsevierStylePara elsevierViewall">This research did not receive any specific grant from funding agencies in the public&#44; commercial&#44; or not-for-profit sectors&#46;</p></span><span id="sec0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0010">Conflict of interest</span><p id="par0015" class="elsevierStylePara elsevierViewall">None&#46;</p></span></span>"
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                      "titulo" => "Pulmonary capillaritis and alveolar hemorrhage&#46; Update on diagnosis and management"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "R&#46;J&#46; Green"
                            1 => "S&#46;J&#46; Ruoss"
                            2 => "S&#46;A&#46; Kraft"
                            3 => "S&#46;R&#46; Duncan"
                            4 => "G&#46;J&#46; Berry"
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                        "volumen" => "110"
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                            3 => "J&#46;C&#46; Lee"
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