Estudio por el metodo de doble ciego de un broncodilatador beta-estimulante: Hexoprenalina
Study by the double blind method of beta-stimulating bronchodilator: Hexopenaline
J. Castillo Gómez, M. Díaz Fernández
Sección de Fisiopatología Respiratoria. Ciudad Sanitaria Virgen del Rodo. Sevilla
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Guallar Ballester, J. Guallar Segarra, F. Sanjuan Rodríguez" "autores" => array:3 [ 0 => array:2 [ "nombre" => "J." "apellidos" => "Guallar Ballester" ] 1 => array:2 [ "nombre" => "J." "apellidos" => "Guallar Segarra" ] 2 => array:2 [ "nombre" => "F." "apellidos" => "Sanjuan Rodríguez" ] ] ] ] ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0300289615327344?idApp=UINPBA00003Z" "url" => "/03002896/0000001200000003/v1_201509151247/S0300289615327344/v1_201509151247/es/main.assets" ] "es" => array:11 [ "idiomaDefecto" => true "titulo" => "Estudio por el metodo de doble ciego de un broncodilatador beta-estimulante: Hexoprenalina" "tieneTextoCompleto" => 0 "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "146" "paginaFinal" => "152" ] ] "autores" => array:1 [ 0 => array:3 [ "autoresLista" => "J. Castillo Gómez, M. Díaz Fernández" "autores" => array:2 [ 0 => array:2 [ "nombre" => "J." "apellidos" => "Castillo Gómez" ] 1 => array:2 [ "nombre" => "M." "apellidos" => "Díaz Fernández" ] ] "afiliaciones" => array:1 [ 0 => array:2 [ "entidad" => "Sección de Fisiopatología Respiratoria. Ciudad Sanitaria Virgen del Rodo. Sevilla" "identificador" => "aff0005" ] ] ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Study by the double blind method of beta-stimulating bronchodilator: Hexopenaline" ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "tieneResumen" => true "resumen" => array:2 [ "es" => array:2 [ "titulo" => "Resumen" "resumen" => "<span id="abst0005" class="elsevierStyleSection elsevierViewall"><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Los autores estudian por el método de doble ciego, los efectos que producen en 50 sujetos asmáticos, la administración de tres aerosoles distintos, agua bidestilada, Hexoprenalina y otro beta-estimulante (orciprenalina), comprobando que la acción de la Hexoprenalina es superior en cuanto a la mejoría de VC, MMEF y sobre todo de las resistencias globales y parciales. También se comprueba que está prácticamente desprovista de efectos secundarios en cuanto a alteraciones de la frecuencia, ritmo y T.A. En este sentido, el tratamiento con el otro, orciprenalina, produce efectos secundarios muy llamativos.</p><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Se realiza también el estudio estadístico de las posibles relaciones existentes entre los valores basales de los distintos volúmenes, flujos y resistencias y las posibles relaciones existentes entre las mejorías de estos parámetros tras la administración de los tres aerosoles considerados.</p></span>" ] "en" => array:2 [ "titulo" => "Summary" "resumen" => "<span id="abst0010" class="elsevierStyleSection elsevierViewall"><p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">The authors study by the double blind method the effects that the administration of three different aerosols, bidistilled water, Hexoprenaline and another beta-stimulant (orciprenaline), produced on 50 asthmatic subjects. It was confirmed that the action of Hexoprenaline is superior with respect to the improvement of VC, MMEF and especially of global and partial resistances. It was also confirmed that this product practically has no secondary effeets with respect to alterations of frequeney, rhythm and T.A. In this sense, treatment with another product, orciprenaline, produces very notable secondary effects.</p><p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">The authors also made a statistical study of the possible relations that exist between the basal values of the different volumes, flows and resistances, and the possible relations that exist between the improvement of these parameters after the administration of the three aerosols taken into consideration.</p></span>" ] ] "bibliografia" => array:2 [ "titulo" => "Bibliografia" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:22 [ 0 => array:3 [ "identificador" => "bib0005" "etiqueta" => "1." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Efectos de la inhalación del aerosol en el epitelio vibrátil" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "J. 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