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Clariana Pal, J.P. Díaz Jiménez, R. Coll Artés, L. Muñoz Díaz" "autores" => array:4 [ 0 => array:2 [ "nombre" => "A." "apellidos" => "Clariana Pal" ] 1 => array:2 [ "nombre" => "J.P." "apellidos" => "Díaz Jiménez" ] 2 => array:2 [ "nombre" => "R." "apellidos" => "Coll Artés" ] 3 => array:2 [ "nombre" => "L." "apellidos" => "Muñoz Díaz" ] ] ] ] ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0300289615325060?idApp=UINPBA00003Z" "url" => "/03002896/0000001600000001/v1_201509151242/S0300289615325060/v1_201509151242/es/main.assets" ] "es" => array:12 [ "idiomaDefecto" => true "titulo" => "Analisis citogenetico de exudados pleurales sospechosos de malignidad" "tieneTextoCompleto" => 0 "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "7" "paginaFinal" => "11" ] ] "autores" => array:1 [ 0 => array:3 [ "autoresLista" => "L. García Quesada, J.A. Portero Sánchez, J.A. Cambronero Galache" "autores" => array:3 [ 0 => array:3 [ "nombre" => "L." "apellidos" => "García Quesada" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">*</span>" "identificador" => "aff0005" ] ] ] 1 => array:3 [ "nombre" => "J.A." "apellidos" => "Portero Sánchez" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">**</span>" "identificador" => "aff0010" ] ] ] 2 => array:3 [ "nombre" => "J.A." "apellidos" => "Cambronero Galache" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">***</span>" "identificador" => "aff0015" ] ] ] ] "afiliaciones" => array:3 [ 0 => array:3 [ "entidad" => "Departamento de Genética. Fundación Jiménez. Díaz, Madrid" "etiqueta" => "*" "identificador" => "aff0005" ] 1 => array:3 [ "entidad" => "Departamento de Genética. Fundación Jiménez. Díaz, Madrid" "etiqueta" => "**" "identificador" => "aff0010" ] 2 => array:3 [ "entidad" => "Departamento de Medicina Interna. Fundación Jiménez. Díaz, Madrid" "etiqueta" => "***" "identificador" => "aff0015" ] ] ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Cytogenetical analysis of pleurai exudates of suspected malignancy" ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "1979-07-19" "tieneResumen" => true "resumen" => array:2 [ "es" => array:2 [ "titulo" => "Resumen" "resumen" => "<span id="absec0005" class="elsevierStyleSection elsevierViewall"><p id="sp0005" class="elsevierStyleSimplePara elsevierViewall">Presentamos una nueva técnica para realizar el diagnóstico de malignidad en derrames pleurales sospechosos. Consiste en el análisis citogenético del exudado en busca de hiperdiploidia o marcadores cromosómicos. Se realizó la técnica sobre 14 muestras que, al tiempo, fueron estudiadas desde e punto de vista citológico e histológico.</p><p id="sp0010" class="elsevierStyleSimplePara elsevierViewall">En relación a la citología, ambos métodos revelaron similar fiabilidad; er ningún caso se obtuvieron falsos posi tivos, y en 2 se hallaron falsos negati vos, igual porcentaje que en la citología. De los 9 casos tumorales estudia dos, se hizo el diagnóstico en 7; de ellos, en 6 se halló hiperdiploidia en e porcentaje que exigía nuestro criteric de malignidad, y en 1 se hallaron marcadores cromosómicos.</p><p id="sp0015" class="elsevierStyleSimplePara elsevierViewall">El interés de esta técnica residiría er su rapidez, su fiabilidad y la búsquedr de marcadores cromosómicos específicos de cada proceso tumoral.</p></span>" ] "en" => array:2 [ "titulo" => "Summary" "resumen" => "<span id="absec0010" class="elsevierStyleSection elsevierViewall"><p id="sp0020" class="elsevierStyleSimplePara elsevierViewall">The authors present a new techniquf for carrying out the diagnosis o malignancy in suspicious pleura exudates. This technique consists ii cytogenetical analysis of the exudati searching for polyploidy or chromo somal markers. This technique wa; used for 14 samples which were alsc studied ar the same time from the cy tologic and histological point of view</p><p id="sp0025" class="elsevierStyleSimplePara elsevierViewall">In relation to cytology, both methoc revealed similar trustworthiness; in m case were false positives obtained, bu in two cases false negatives wen found, the same percentaje as that ii cytology. Of the nine cases of tumor: studied, the diagnosis was made in 7 Of these seven, polyploidy was founc in the percentage that the authors criteria of malignancy required, and ii one case chromosomal markers wen found.</p><p id="sp0030" class="elsevierStyleSimplePara elsevierViewall">The interest of this technique lies it its rapidity, reliability and the searcl for specific chromosomal markers o each tumorous process.</p></span>" ] ] "bibliografia" => array:2 [ "titulo" => "Bibliografia" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:20 [ 0 => array:3 [ "identificador" => "bib0005" "etiqueta" => "1." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Chromosome analyses of a human ovarian cystocarcinoma in the ascites form" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "E. Hansen-Melander" 1 => "S. Kullander" 2 => "Y. 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2024 November | 2 | 4 | 6 |
2024 October | 31 | 15 | 46 |
2024 September | 31 | 14 | 45 |
2024 August | 40 | 29 | 69 |
2024 July | 32 | 21 | 53 |
2024 June | 51 | 39 | 90 |
2024 May | 36 | 26 | 62 |
2024 April | 39 | 24 | 63 |
2024 March | 33 | 31 | 64 |
2024 February | 39 | 32 | 71 |
2024 January | 0 | 3 | 3 |
2023 December | 0 | 2 | 2 |
2023 November | 0 | 1 | 1 |
2023 October | 0 | 1 | 1 |
2023 September | 0 | 1 | 1 |
2023 August | 0 | 2 | 2 |
2023 July | 0 | 10 | 10 |
2023 June | 0 | 1 | 1 |
2023 May | 0 | 1 | 1 |
2023 March | 4 | 2 | 6 |
2023 February | 17 | 15 | 32 |
2023 January | 23 | 17 | 40 |
2022 December | 23 | 24 | 47 |
2022 November | 34 | 16 | 50 |
2022 October | 26 | 28 | 54 |
2022 September | 24 | 38 | 62 |
2022 August | 32 | 39 | 71 |
2022 July | 13 | 30 | 43 |
2022 June | 23 | 79 | 102 |
2022 May | 22 | 33 | 55 |
2022 April | 27 | 34 | 61 |
2022 March | 31 | 39 | 70 |
2022 February | 21 | 22 | 43 |
2022 January | 26 | 25 | 51 |
2021 December | 15 | 33 | 48 |
2021 November | 14 | 21 | 35 |
2021 October | 43 | 26 | 69 |
2021 September | 32 | 33 | 65 |
2021 August | 15 | 29 | 44 |
2021 July | 15 | 25 | 40 |
2021 June | 13 | 28 | 41 |
2021 May | 6 | 21 | 27 |
2021 April | 17 | 21 | 38 |
2021 March | 26 | 16 | 42 |
2021 February | 29 | 17 | 46 |
2021 January | 12 | 16 | 28 |
2020 December | 14 | 5 | 19 |
2020 November | 10 | 23 | 33 |
2020 October | 17 | 9 | 26 |
2020 September | 8 | 9 | 17 |
2020 August | 11 | 22 | 33 |
2020 July | 16 | 20 | 36 |
2020 June | 10 | 11 | 21 |
2020 May | 11 | 9 | 20 |
2020 April | 14 | 8 | 22 |
2020 March | 19 | 23 | 42 |
2020 February | 18 | 10 | 28 |
2020 January | 19 | 14 | 33 |
2019 December | 16 | 18 | 34 |
2019 November | 5 | 10 | 15 |
2019 October | 9 | 11 | 20 |
2019 September | 23 | 20 | 43 |
2019 August | 15 | 17 | 32 |
2019 July | 15 | 22 | 37 |
2019 June | 12 | 27 | 39 |
2019 May | 11 | 32 | 43 |
2019 April | 16 | 24 | 40 |
2019 March | 9 | 17 | 26 |
2019 February | 5 | 6 | 11 |
2019 January | 6 | 1 | 7 |
2018 December | 6 | 16 | 22 |
2018 November | 14 | 10 | 24 |
2018 October | 24 | 8 | 32 |
2018 September | 10 | 7 | 17 |
2018 May | 5 | 1 | 6 |
2018 April | 6 | 5 | 11 |
2018 March | 4 | 5 | 9 |
2018 February | 6 | 14 | 20 |
2018 January | 6 | 6 | 12 |
2017 December | 13 | 14 | 27 |
2017 November | 10 | 7 | 17 |
2017 October | 12 | 10 | 22 |
2017 September | 5 | 10 | 15 |
2017 August | 10 | 12 | 22 |
2017 July | 3 | 5 | 8 |
2017 June | 8 | 9 | 17 |
2017 May | 8 | 7 | 15 |
2017 April | 10 | 3 | 13 |
2017 March | 4 | 9 | 13 |
2017 February | 5 | 6 | 11 |
2017 January | 2 | 2 | 4 |
2016 December | 10 | 4 | 14 |
2016 November | 14 | 7 | 21 |
2016 October | 20 | 16 | 36 |
2016 September | 14 | 13 | 27 |
2016 August | 15 | 4 | 19 |
2016 July | 15 | 5 | 20 |
2016 June | 22 | 11 | 33 |
2016 May | 17 | 4 | 21 |
2016 April | 8 | 0 | 8 |
2016 March | 8 | 0 | 8 |
2016 February | 10 | 0 | 10 |
2016 January | 20 | 6 | 26 |
2015 December | 25 | 12 | 37 |
2015 November | 24 | 6 | 30 |
2015 October | 6 | 1 | 7 |
2015 September | 2 | 0 | 2 |