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        "resumen" => "<span id="abst0005" class="elsevierStyleSection elsevierViewall"><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">La alta prevalencia del s&#237;ndrome de apnea del sue&#241;o &#40;SAS&#41; y el elevado coste de la polisomnograf&#237;a &#40;PLS&#41; precisan el desarrollo de sistemas de identificaci&#243;n del SAS m&#225;s baratos&#46; El MESAM IV es un equipo ambulatorio que registra las variaciones de la saturaci&#243;n de ox&#237;geno &#40;SO<span class="elsevierStyleInf">2</span>&#41;&#44; de la frecuencia card&#237;aca &#40;FC&#41; y la presencia de ronquidos &#40;RQ&#41;&#46; El aparato es capaz de hacer una lectura autom&#225;tica y tambi&#233;n puede realizarse de forma manual seg&#250;n el &#237;ndice de eventos &#40;IE&#41; interrelacionando las tres variables a trav&#233;s de un registro gr&#225;fico&#46; Se estudiaron de forma simult&#225;nea&#44; con PLS y MESAM IV&#44; 51 sujetos enviados a la unidad de sue&#241;o desde la consulta externa de neumolog&#237;a por sospecha cl&#237;nica de SAS&#46; La PLS se interpret&#243; de forma manual en &#233;pocas de 30 segundos seg&#250;n las recomendaciones de la American Thoracic Society&#44; considerando criterio de SAS un &#237;ndice de apnea&#47;hipopnea &#40;IAH&#41; &#8805; 10 por hora de sue&#241;o&#46; Hubo 32 sujetos &#40;63&#37;&#41; que tuvieron SAS por la PLS&#46; El grado de concordancia entre el an&#225;lisis autom&#225;tico de SO<span class="elsevierStyleInf">2</span>&#44; FC y RQ con el IAH fue s&#243;lo moderado &#40;coeficiente de correlaci&#243;n intraclase -CCI- de 0&#44;50&#44; 0&#44;40 y 0&#44;53&#44; respectivamente&#41; e inferior al an&#225;lisis manual con el IE &#40;CCI de 0&#44;77&#41;&#46; El estudio de eficacia diagn&#243;stica en t&#233;rminos de sensibilidad&#44; especificidad&#44; valor predictivo positivo &#40;VPP&#41; y valor predictivo negativo &#40;VPN&#41; para el an&#225;lisis autom&#225;tico fue&#58; SO<span class="elsevierStyleInf">2</span> &#40;sensibilidad&#44; 94&#37;&#59; especificidad&#44; 26&#37;&#59; VPP&#44; 68&#37;&#44; y VPN&#44; 71&#37;&#41;&#59; FC &#40;sensibilidad&#44; 59&#37;&#59; especificidad&#44; 58&#37;&#59; VPP&#44; 70&#37;&#44; y VPN&#44; 46&#37;&#41;&#59; RQ &#40;sensibilidad&#44; 84&#37;&#59; especificidad&#44; 26&#37;&#59; VPP&#44; 66&#37;&#44; y VPN&#44; 50&#37;&#41;&#46; Para el an&#225;lisis manual &#40;IE&#41; los resultados fueron m&#225;s v&#225;lidos&#58; sensibilidad&#44; 100&#37;&#59; especificidad&#44; 84&#37;&#59; VPP&#44; 91&#37;&#44; y VPN&#44; 100&#37;&#46; Por otra parte&#44; al excluir los pacientes con limitaci&#243;n cr&#243;nica al flujo a&#233;reo &#40;LCFA&#41; m&#225;s que leve&#44; causa potencial de falsos positivos&#44; los resultados mejoraron&#58; sensibilidad&#44; 100&#37;&#59; especificidad&#44; 91&#37;&#59; VPP&#44; 96&#37;&#44; y VPN&#44; 100&#37;&#46; Estos resultados muestran que el MESAM IV es de gran ayuda en el diagn&#243;stico de SAS y permite seleccionar mejor la poblaci&#243;n a la que va a someterse a la PLS&#46;</p></span>"
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        "resumen" => "<span id="abst0010" class="elsevierStyleSection elsevierViewall"><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">The development of inexpensive tools for diagnosing sleep apnea syndrome &#40;SAS&#41; is a result of the high prevalence of this condition and of the high cost of polysomnograms &#40;PS&#41;&#46; MESAM IV is a portable device that records changes in oxigen saturation &#40;S02&#41;&#44; heart rate &#40;HR&#41; and snoring &#40;S&#41;&#46; Readings can be automatic or manual&#44; the latter in function of an events index &#40;El&#41;&#44; with a graph of the three variables generated&#46; We carried out a simuitaneous study of 51 subjects suspected of having SAS who were referred to the sleep unit by the pneumology outpatient clinic&#46; PS was interpreted manually at 30-sec intervals as recommended by the American Thoracic Society&#46; An apnea&#47;hypoapnea index &#40;AHI&#41; &#8805; 10&#47;&#47;hour of sleep was used as the cutoff point for SAS&#46; Thirty-two &#40;63&#37;&#41; subjects were found to have SAS as indicated by PS&#46; The rate of agreement between AHI and automatic analysis of S02&#44; HR and S was only moderate &#40;intra-group correlation coefficients -ICC- of 0&#46;50&#44; 0&#46;40&#44; and 0&#46;53&#44; respectively&#41; and was inferior to manual analysis with EI &#40;ICC of 0&#46;77&#41;&#46; Assessment of diagnostic efficacy of automatic analysis in terms of sensitivity &#40;SEN&#41;&#44; specificity &#40;SPE&#41;&#44; positive predictive value &#40;PPV&#41; and negative predictive value &#40;NPV&#41; yielded the following results&#58; S02 &#40;SEN 94&#37;&#44; SPE 26&#37;&#44; PPV 68&#37; and NPV 71&#37;&#41;&#44; HR &#40;SEN 59&#37;&#44; SPE 58&#37;&#44; PPV 70&#37;&#44; NPV 46&#37;&#41;&#59; S &#40;SEN 84&#37;&#44; SPE 26&#37;&#44; PPV 66&#37;&#44; NPV 50&#37;&#41;&#46; Manual analysis &#40;EI&#41; gave more valid results &#40;SEN 100&#37;&#44; SPE 84&#37;&#44; PPV 91&#37;&#44; NPV 100&#37;&#41;&#46; If patients with chronic obstructive lung disease are excluded&#44; however&#44; the results for automatic analysis improve&#58; SEN 100&#37;&#44; SPE 91&#37;&#44; PPV 96&#37;&#44; NPV 100&#37;&#46; These results show that MESAM IV is of great help in diagnosing SAS&#44; allowing better screening for identifying candidates for PS&#46;</p></span>"
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Validez de un sistema de registro portátil (MESAM IV) para el diagnóstico del síndrome de apnea del sueño
Validity of portable recording (MESAM IV) for diagnosis of sleep apnea syndrome (SAS)
J. Durán Cantolla*,1, S. Esnaola Sukia**, R. Rubio Aramendi***, C. Egea Santaolalla*
* Sección de Neumología. Unidad de Sueño. Vitoria-Gasteiz
** Dirección de Información, Docencia e Investigación Sanitaria. Departamento de Sanidad. Gobiernno Vasco
*** Servicio de Neurofisiología Clínica. Hospital de Txagorritxu. Vitoria-Gasteiz
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    "titulo" => "Validez de un sistema de registro port&#225;til &#40;MESAM IV&#41; para el diagn&#243;stico del s&#237;ndrome de apnea del sue&#241;o"
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        "titulo" => "Validity of portable recording &#40;MESAM IV&#41; for diagnosis of sleep apnea syndrome &#40;SAS&#41;"
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        "resumen" => "<span id="abst0005" class="elsevierStyleSection elsevierViewall"><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">La alta prevalencia del s&#237;ndrome de apnea del sue&#241;o &#40;SAS&#41; y el elevado coste de la polisomnograf&#237;a &#40;PLS&#41; precisan el desarrollo de sistemas de identificaci&#243;n del SAS m&#225;s baratos&#46; El MESAM IV es un equipo ambulatorio que registra las variaciones de la saturaci&#243;n de ox&#237;geno &#40;SO<span class="elsevierStyleInf">2</span>&#41;&#44; de la frecuencia card&#237;aca &#40;FC&#41; y la presencia de ronquidos &#40;RQ&#41;&#46; El aparato es capaz de hacer una lectura autom&#225;tica y tambi&#233;n puede realizarse de forma manual seg&#250;n el &#237;ndice de eventos &#40;IE&#41; interrelacionando las tres variables a trav&#233;s de un registro gr&#225;fico&#46; Se estudiaron de forma simult&#225;nea&#44; con PLS y MESAM IV&#44; 51 sujetos enviados a la unidad de sue&#241;o desde la consulta externa de neumolog&#237;a por sospecha cl&#237;nica de SAS&#46; La PLS se interpret&#243; de forma manual en &#233;pocas de 30 segundos seg&#250;n las recomendaciones de la American Thoracic Society&#44; considerando criterio de SAS un &#237;ndice de apnea&#47;hipopnea &#40;IAH&#41; &#8805; 10 por hora de sue&#241;o&#46; Hubo 32 sujetos &#40;63&#37;&#41; que tuvieron SAS por la PLS&#46; El grado de concordancia entre el an&#225;lisis autom&#225;tico de SO<span class="elsevierStyleInf">2</span>&#44; FC y RQ con el IAH fue s&#243;lo moderado &#40;coeficiente de correlaci&#243;n intraclase -CCI- de 0&#44;50&#44; 0&#44;40 y 0&#44;53&#44; respectivamente&#41; e inferior al an&#225;lisis manual con el IE &#40;CCI de 0&#44;77&#41;&#46; El estudio de eficacia diagn&#243;stica en t&#233;rminos de sensibilidad&#44; especificidad&#44; valor predictivo positivo &#40;VPP&#41; y valor predictivo negativo &#40;VPN&#41; para el an&#225;lisis autom&#225;tico fue&#58; SO<span class="elsevierStyleInf">2</span> &#40;sensibilidad&#44; 94&#37;&#59; especificidad&#44; 26&#37;&#59; VPP&#44; 68&#37;&#44; y VPN&#44; 71&#37;&#41;&#59; FC &#40;sensibilidad&#44; 59&#37;&#59; especificidad&#44; 58&#37;&#59; VPP&#44; 70&#37;&#44; y VPN&#44; 46&#37;&#41;&#59; RQ &#40;sensibilidad&#44; 84&#37;&#59; especificidad&#44; 26&#37;&#59; VPP&#44; 66&#37;&#44; y VPN&#44; 50&#37;&#41;&#46; Para el an&#225;lisis manual &#40;IE&#41; los resultados fueron m&#225;s v&#225;lidos&#58; sensibilidad&#44; 100&#37;&#59; especificidad&#44; 84&#37;&#59; VPP&#44; 91&#37;&#44; y VPN&#44; 100&#37;&#46; Por otra parte&#44; al excluir los pacientes con limitaci&#243;n cr&#243;nica al flujo a&#233;reo &#40;LCFA&#41; m&#225;s que leve&#44; causa potencial de falsos positivos&#44; los resultados mejoraron&#58; sensibilidad&#44; 100&#37;&#59; especificidad&#44; 91&#37;&#59; VPP&#44; 96&#37;&#44; y VPN&#44; 100&#37;&#46; Estos resultados muestran que el MESAM IV es de gran ayuda en el diagn&#243;stico de SAS y permite seleccionar mejor la poblaci&#243;n a la que va a someterse a la PLS&#46;</p></span>"
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        "resumen" => "<span id="abst0010" class="elsevierStyleSection elsevierViewall"><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">The development of inexpensive tools for diagnosing sleep apnea syndrome &#40;SAS&#41; is a result of the high prevalence of this condition and of the high cost of polysomnograms &#40;PS&#41;&#46; MESAM IV is a portable device that records changes in oxigen saturation &#40;S02&#41;&#44; heart rate &#40;HR&#41; and snoring &#40;S&#41;&#46; Readings can be automatic or manual&#44; the latter in function of an events index &#40;El&#41;&#44; with a graph of the three variables generated&#46; We carried out a simuitaneous study of 51 subjects suspected of having SAS who were referred to the sleep unit by the pneumology outpatient clinic&#46; PS was interpreted manually at 30-sec intervals as recommended by the American Thoracic Society&#46; An apnea&#47;hypoapnea index &#40;AHI&#41; &#8805; 10&#47;&#47;hour of sleep was used as the cutoff point for SAS&#46; Thirty-two &#40;63&#37;&#41; subjects were found to have SAS as indicated by PS&#46; The rate of agreement between AHI and automatic analysis of S02&#44; HR and S was only moderate &#40;intra-group correlation coefficients -ICC- of 0&#46;50&#44; 0&#46;40&#44; and 0&#46;53&#44; respectively&#41; and was inferior to manual analysis with EI &#40;ICC of 0&#46;77&#41;&#46; Assessment of diagnostic efficacy of automatic analysis in terms of sensitivity &#40;SEN&#41;&#44; specificity &#40;SPE&#41;&#44; positive predictive value &#40;PPV&#41; and negative predictive value &#40;NPV&#41; yielded the following results&#58; S02 &#40;SEN 94&#37;&#44; SPE 26&#37;&#44; PPV 68&#37; and NPV 71&#37;&#41;&#44; HR &#40;SEN 59&#37;&#44; SPE 58&#37;&#44; PPV 70&#37;&#44; NPV 46&#37;&#41;&#59; S &#40;SEN 84&#37;&#44; SPE 26&#37;&#44; PPV 66&#37;&#44; NPV 50&#37;&#41;&#46; Manual analysis &#40;EI&#41; gave more valid results &#40;SEN 100&#37;&#44; SPE 84&#37;&#44; PPV 91&#37;&#44; NPV 100&#37;&#41;&#46; If patients with chronic obstructive lung disease are excluded&#44; however&#44; the results for automatic analysis improve&#58; SEN 100&#37;&#44; SPE 91&#37;&#44; PPV 96&#37;&#44; NPV 100&#37;&#46; These results show that MESAM IV is of great help in diagnosing SAS&#44; allowing better screening for identifying candidates for PS&#46;</p></span>"
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                          "etal" => false
                          "autores" => array:6 [
                            0 => "S&#46; Gyulay"
                            1 => "D&#46; Gould"
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                            3 => "D&#46; Pond"
                            4 => "A&#46; Mant"
                            5 => "N&#46;S&#46; Saunders"
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                        "tituloSerie" => "Sleep"
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                            3 => "D&#46; O&#8217;Connell"
                            4 => "A&#46; Eyland"
                            5 => "A&#46; Mant"
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                          "etal" => false
                          "autores" => array:4 [
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                            3 => "R&#46; Pirskanen"
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                      "titulo" => "Cyclical variation of the hear rate in sleep apnea syndrome&#58; Mechanisms and usefulness of 24 h electrocardiography as a screening technique"
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                          "etal" => false
                          "autores" => array:4 [
                            0 => "C&#46; Guilleminault"
                            1 => "R&#46; Connoly"
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                            3 => "R&#46; Melvin"
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                      "titulo" => "Bradycardia during sleep apnea"
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                          "etal" => true
                          "autores" => array:3 [
                            0 => "C&#46; Zwillich"
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ISSN: 03002896
Original language: Spanish
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