Efectos de la presión positiva continua nasal (CPAPn) sobre la función pulmonar en pacientes con síndrome de apnea obstructiva del sueño (SAOS)
Effects of nasal continuous positive airways pressure on lung function in patients with obstructive sleep apnea syndrome
R. Vázquez Oliva*, S. Cano Gómez, F. Capote Gil, M.A. Sánchez Armengol, C. Carmona Bernal, J. Castillo Gómez
Servicio de Neumología. Hospital Universitario Virgen del Rocío. Sevilla
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"apellidos" => "Vázquez Oliva" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">*</span>" "identificador" => "cor0005" ] ] ] 1 => array:2 [ "nombre" => "S." "apellidos" => "Cano Gómez" ] 2 => array:2 [ "nombre" => "F." "apellidos" => "Capote Gil" ] 3 => array:2 [ "nombre" => "M.A." "apellidos" => "Sánchez Armengol" ] 4 => array:2 [ "nombre" => "C." "apellidos" => "Carmona Bernal" ] 5 => array:2 [ "nombre" => "J." "apellidos" => "Castillo Gómez" ] ] "afiliaciones" => array:1 [ 0 => array:2 [ "entidad" => "Servicio de Neumología. Hospital Universitario Virgen del Rocío. Sevilla" "identificador" => "aff0005" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "*" "correspondencia" => "Correspondencia: Celinda, 1-2, 2.° A. 41002 Sevilla." ] ] ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Effects of nasal continuous positive airways pressure on lung function in patients with obstructive sleep apnea syndrome" ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "1994-02-03" "fechaAceptado" => "1994-06-28" "PalabrasClave" => array:2 [ "es" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palabras clave" "identificador" => "xpalclavsec546361" "palabras" => array:3 [ 0 => "SAOS" 1 => "EPOC" 2 => "CPAPn" ] ] ] "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Key words" "identificador" => "xpalclavsec546360" "palabras" => array:3 [ 0 => "Obstructive sleep apnea syndrome" 1 => "Chronic obstructive pulmonary disease" 2 => "Nasal continuous positive airways pressure" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "es" => array:1 [ "resumen" => "<span id="abst0005" class="elsevierStyleSection elsevierViewall"><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Sesenta y un pacientes con síndrome de apnea obstructiva del sueño (SAOS), veintiséis de los cuales tenían enfermedad pulmonar obstructiva crónica (EPOC) asociada, recibieron tratamiento con presión positiva continua nasal (CPAPn). Para evaluar los efectos de este dispositivo sobre la función pulmonar diurna se analizaron los tests de función pulmonar practicados antes del tratamiento con CPAPn y tras un período medio de seguimiento de 12 meses (valores extremos: 222 meses). En el grupo de pacientes con SAOS y EPOC existió un descenso significativo de la PaC0<span class="elsevierStyleInf">2</span> (p < 0,007), de la resistencia de la vía aérea (Raw) (p < 0,002) y del volumen residual (RV) (p < 0,01), y un incremento de la capacidad vital forzada (FVC) (p < 0,04) y de la presión inspiratoria máxima (PIM) (p < 0,02). No encontramos cambios manifiestos en la función pulmonar de pacientes con SAOS aislado. En los 15 pacientes inicialmente hipoxémicos la PaO<span class="elsevierStyleInf">2</span> se incrementó tras el seguimiento (p < 0,001). Concluimos que tras tratamiento con CPAPn los mayores cambios en la función respiratoria se producen en el grupo de pacientes con SAOS y EPOC asociada, en el que también se produce una ligera disminución del peso corporal. Los cambios en este grupo podrían deberse a un descenso de la auto-PEEP y a una disminución del peso.</p></span>" ] "en" => array:1 [ "resumen" => "<span id="abst0010" class="elsevierStyleSection elsevierViewall"><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Sixty-one patients with obstructive sleep apnea syndrome (OSAS), 26 of whom also had chronic obstructive pulmonary disease (COPD), received treatment by nasal continuous positive airways pressure (nCPAP). To evalúate the effects of this device on daytime lung function, we analyzed pulmonary function tests before treatment with nCPAP and after a mean follow-up period of 12 months (range: 2-22 months). In patients with both OSAS and COPD, we observed a significant decrease in PaCO<span class="elsevierStyleInf">2</span> (p < 0.007), in airways resistance (p < 0.002) and in residual volume (p < 0.01); for these same patients we recorded increases in forced vital capacity (p < 0.04) and maximum inspiratory pressure (p < 0.02). We saw no change in lung function in patients with OSAS only. PaO<span class="elsevierStyleInf">2</span> increased after treatment in the 15 patients who were initially hypoxemic (p < 0.001). We conclude that after treatment with nCPAP, the greatest changes in respiratory function occur in patients with both OSAS and COPD, who also experience slight decrease in body weight. These changes may be explained by a decrease in auto-PEEP and weight loss.</p></span>" ] ] "bibliografia" => array:2 [ "titulo" => "Bibliografía" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:24 [ 0 => array:3 [ "identificador" => "bib0005" "etiqueta" => "1." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Positive nasal airway pressure eliminates snoring as well as obstructive sleep apnea" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "R.B. Berry" 1 => "A.J. Block" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Chest" "fecha" => "1984" "volumen" => "85" "paginaInicial" => "15" "paginaFinal" => "20" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/6360571" "web" => "Medline" ] ] ] ] ] ] ] ] 1 => array:3 [ "identificador" => "bib0010" "etiqueta" => "2." 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| Year/Month | Html | Total | |
|---|---|---|---|
| 2024 November | 3 | 2 | 5 |
| 2024 October | 42 | 17 | 59 |
| 2024 September | 48 | 23 | 71 |
| 2024 August | 64 | 37 | 101 |
| 2024 July | 33 | 34 | 67 |
| 2024 June | 58 | 49 | 107 |
| 2024 May | 43 | 30 | 73 |
| 2024 April | 25 | 19 | 44 |
| 2024 March | 39 | 26 | 65 |
| 2024 February | 34 | 39 | 73 |
| 2024 January | 0 | 4 | 4 |
| 2023 November | 0 | 2 | 2 |
| 2023 October | 0 | 2 | 2 |
| 2023 September | 0 | 4 | 4 |
| 2023 July | 0 | 18 | 18 |
| 2023 June | 0 | 3 | 3 |
| 2023 May | 0 | 1 | 1 |
| 2023 March | 5 | 7 | 12 |
| 2023 February | 33 | 19 | 52 |
| 2023 January | 36 | 30 | 66 |
| 2022 December | 41 | 24 | 65 |
| 2022 November | 45 | 19 | 64 |
| 2022 October | 31 | 40 | 71 |
| 2022 September | 25 | 24 | 49 |
| 2022 August | 34 | 37 | 71 |
| 2022 July | 17 | 36 | 53 |
| 2022 June | 25 | 31 | 56 |
| 2022 May | 29 | 29 | 58 |
| 2022 April | 34 | 38 | 72 |
| 2022 March | 30 | 40 | 70 |
| 2022 February | 34 | 33 | 67 |
| 2022 January | 26 | 34 | 60 |
| 2021 December | 18 | 45 | 63 |
| 2021 November | 17 | 34 | 51 |
| 2021 October | 23 | 48 | 71 |
| 2021 September | 19 | 45 | 64 |
| 2021 August | 7 | 38 | 45 |
| 2021 July | 12 | 38 | 50 |
| 2021 June | 21 | 42 | 63 |
| 2021 May | 19 | 33 | 52 |
| 2021 April | 38 | 43 | 81 |
| 2021 March | 13 | 37 | 50 |
| 2021 February | 11 | 17 | 28 |
| 2021 January | 14 | 23 | 37 |
| 2020 December | 18 | 26 | 44 |
| 2020 November | 20 | 23 | 43 |
| 2020 October | 16 | 19 | 35 |
| 2020 September | 10 | 21 | 31 |
| 2020 August | 20 | 27 | 47 |
| 2020 July | 28 | 16 | 44 |
| 2020 June | 16 | 21 | 37 |
| 2020 May | 9 | 23 | 32 |
| 2020 April | 24 | 14 | 38 |
| 2020 March | 15 | 30 | 45 |
| 2020 February | 21 | 34 | 55 |
| 2020 January | 22 | 22 | 44 |
| 2019 December | 16 | 39 | 55 |
| 2019 November | 8 | 15 | 23 |
| 2019 October | 8 | 19 | 27 |
| 2019 September | 14 | 24 | 38 |
| 2019 August | 9 | 9 | 18 |
| 2019 July | 24 | 28 | 52 |
| 2019 June | 19 | 24 | 43 |
| 2019 May | 22 | 31 | 53 |
| 2019 April | 33 | 49 | 82 |
| 2019 March | 16 | 27 | 43 |
| 2019 February | 13 | 13 | 26 |
| 2019 January | 11 | 18 | 29 |
| 2018 December | 17 | 19 | 36 |
| 2018 November | 28 | 17 | 45 |
| 2018 October | 26 | 27 | 53 |
| 2018 September | 18 | 8 | 26 |
| 2018 May | 3 | 1 | 4 |
| 2018 April | 6 | 5 | 11 |
| 2018 March | 5 | 10 | 15 |
| 2018 February | 7 | 9 | 16 |
| 2018 January | 6 | 8 | 14 |
| 2017 December | 8 | 15 | 23 |
| 2017 November | 5 | 13 | 18 |
| 2017 October | 9 | 8 | 17 |
| 2017 September | 11 | 18 | 29 |
| 2017 August | 13 | 13 | 26 |
| 2017 July | 3 | 5 | 8 |
| 2017 June | 17 | 43 | 60 |
| 2017 May | 13 | 15 | 28 |
| 2017 April | 6 | 6 | 12 |
| 2017 March | 7 | 8 | 15 |
| 2017 February | 1 | 7 | 8 |
| 2017 January | 5 | 9 | 14 |
| 2016 December | 16 | 9 | 25 |
| 2016 November | 18 | 15 | 33 |
| 2016 October | 20 | 11 | 31 |
| 2016 September | 27 | 15 | 42 |
| 2016 August | 12 | 4 | 16 |
| 2016 July | 19 | 6 | 25 |
| 2016 June | 20 | 8 | 28 |
| 2016 May | 25 | 7 | 32 |
| 2016 April | 17 | 0 | 17 |
| 2016 March | 7 | 1 | 8 |
| 2016 February | 16 | 1 | 17 |
| 2016 January | 12 | 2 | 14 |
| 2015 December | 28 | 16 | 44 |
| 2015 November | 24 | 5 | 29 |
| 2015 October | 8 | 2 | 10 |
| 2015 September | 1 | 0 | 1 |
| 2015 August | 1 | 0 | 1 |
| 2015 June | 1 | 0 | 1 |
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