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        "resumen" => "<span id="abst0005" class="elsevierStyleSection elsevierViewall"><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Sesenta y un pacientes con s&#237;ndrome de apnea obstructiva del sue&#241;o &#40;SAOS&#41;&#44; veintis&#233;is de los cuales ten&#237;an enfermedad pulmonar obstructiva cr&#243;nica &#40;EPOC&#41; asociada&#44; recibieron tratamiento con presi&#243;n positiva continua nasal &#40;CPAPn&#41;&#46; Para evaluar los efectos de este dispositivo sobre la funci&#243;n pulmonar diurna se analizaron los tests de funci&#243;n pulmonar practicados antes del tratamiento con CPAPn y tras un per&#237;odo medio de seguimiento de 12 meses &#40;valores extremos&#58; 222 meses&#41;&#46; En el grupo de pacientes con SAOS y EPOC existi&#243; un descenso significativo de la PaC0<span class="elsevierStyleInf">2</span> &#40;p &#60; 0&#44;007&#41;&#44; de la resistencia de la v&#237;a a&#233;rea &#40;Raw&#41; &#40;p &#60; 0&#44;002&#41; y del volumen residual &#40;RV&#41; &#40;p &#60; 0&#44;01&#41;&#44; y un incremento de la capacidad vital forzada &#40;FVC&#41; &#40;p &#60; 0&#44;04&#41; y de la presi&#243;n inspiratoria m&#225;xima &#40;PIM&#41; &#40;p &#60; 0&#44;02&#41;&#46; No encontramos cambios manifiestos en la funci&#243;n pulmonar de pacientes con SAOS aislado&#46; En los 15 pacientes inicialmente hipox&#233;micos la PaO<span class="elsevierStyleInf">2</span> se increment&#243; tras el seguimiento &#40;p &#60; 0&#44;001&#41;&#46; Concluimos que tras tratamiento con CPAPn los mayores cambios en la funci&#243;n respiratoria se producen en el grupo de pacientes con SAOS y EPOC asociada&#44; en el que tambi&#233;n se produce una ligera disminuci&#243;n del peso corporal&#46; Los cambios en este grupo podr&#237;an deberse a un descenso de la auto-PEEP y a una disminuci&#243;n del peso&#46;</p></span>"
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        "resumen" => "<span id="abst0010" class="elsevierStyleSection elsevierViewall"><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Sixty-one patients with obstructive sleep apnea syndrome &#40;OSAS&#41;&#44; 26 of whom also had chronic obstructive pulmonary disease &#40;COPD&#41;&#44; received treatment by nasal continuous positive airways pressure &#40;nCPAP&#41;&#46; To eval&#250;ate the effects of this device on daytime lung function&#44; we analyzed pulmonary function tests before treatment with nCPAP and after a mean follow-up period of 12 months &#40;range&#58; 2-22 months&#41;&#46; In patients with both OSAS and COPD&#44; we observed a significant decrease in PaCO<span class="elsevierStyleInf">2</span> &#40;p &#60; 0&#46;007&#41;&#44; in airways resistance &#40;p &#60; 0&#46;002&#41; and in residual volume &#40;p &#60; 0&#46;01&#41;&#59; for these same patients we recorded increases in forced vital capacity &#40;p &#60; 0&#46;04&#41; and maximum inspiratory pressure &#40;p &#60; 0&#46;02&#41;&#46; We saw no change in lung function in patients with OSAS only&#46; PaO<span class="elsevierStyleInf">2</span> increased after treatment in the 15 patients who were initially hypoxemic &#40;p &#60; 0&#46;001&#41;&#46; We conclude that after treatment with nCPAP&#44; the greatest changes in respiratory function occur in patients with both OSAS and COPD&#44; who also experience slight decrease in body weight&#46; These changes may be explained by a decrease in auto-PEEP and weight loss&#46;</p></span>"
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Efectos de la presión positiva continua nasal (CPAPn) sobre la función pulmonar en pacientes con síndrome de apnea obstructiva del sueño (SAOS)
Effects of nasal continuous positive airways pressure on lung function in patients with obstructive sleep apnea syndrome
R. Vázquez Oliva*, S. Cano Gómez, F. Capote Gil, M.A. Sánchez Armengol, C. Carmona Bernal, J. Castillo Gómez
Servicio de Neumología. Hospital Universitario Virgen del Rocío. Sevilla
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        "resumen" => "<span id="abst0005" class="elsevierStyleSection elsevierViewall"><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Sesenta y un pacientes con s&#237;ndrome de apnea obstructiva del sue&#241;o &#40;SAOS&#41;&#44; veintis&#233;is de los cuales ten&#237;an enfermedad pulmonar obstructiva cr&#243;nica &#40;EPOC&#41; asociada&#44; recibieron tratamiento con presi&#243;n positiva continua nasal &#40;CPAPn&#41;&#46; Para evaluar los efectos de este dispositivo sobre la funci&#243;n pulmonar diurna se analizaron los tests de funci&#243;n pulmonar practicados antes del tratamiento con CPAPn y tras un per&#237;odo medio de seguimiento de 12 meses &#40;valores extremos&#58; 222 meses&#41;&#46; En el grupo de pacientes con SAOS y EPOC existi&#243; un descenso significativo de la PaC0<span class="elsevierStyleInf">2</span> &#40;p &#60; 0&#44;007&#41;&#44; de la resistencia de la v&#237;a a&#233;rea &#40;Raw&#41; &#40;p &#60; 0&#44;002&#41; y del volumen residual &#40;RV&#41; &#40;p &#60; 0&#44;01&#41;&#44; y un incremento de la capacidad vital forzada &#40;FVC&#41; &#40;p &#60; 0&#44;04&#41; y de la presi&#243;n inspiratoria m&#225;xima &#40;PIM&#41; &#40;p &#60; 0&#44;02&#41;&#46; No encontramos cambios manifiestos en la funci&#243;n pulmonar de pacientes con SAOS aislado&#46; En los 15 pacientes inicialmente hipox&#233;micos la PaO<span class="elsevierStyleInf">2</span> se increment&#243; tras el seguimiento &#40;p &#60; 0&#44;001&#41;&#46; Concluimos que tras tratamiento con CPAPn los mayores cambios en la funci&#243;n respiratoria se producen en el grupo de pacientes con SAOS y EPOC asociada&#44; en el que tambi&#233;n se produce una ligera disminuci&#243;n del peso corporal&#46; Los cambios en este grupo podr&#237;an deberse a un descenso de la auto-PEEP y a una disminuci&#243;n del peso&#46;</p></span>"
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        "resumen" => "<span id="abst0010" class="elsevierStyleSection elsevierViewall"><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Sixty-one patients with obstructive sleep apnea syndrome &#40;OSAS&#41;&#44; 26 of whom also had chronic obstructive pulmonary disease &#40;COPD&#41;&#44; received treatment by nasal continuous positive airways pressure &#40;nCPAP&#41;&#46; To eval&#250;ate the effects of this device on daytime lung function&#44; we analyzed pulmonary function tests before treatment with nCPAP and after a mean follow-up period of 12 months &#40;range&#58; 2-22 months&#41;&#46; In patients with both OSAS and COPD&#44; we observed a significant decrease in PaCO<span class="elsevierStyleInf">2</span> &#40;p &#60; 0&#46;007&#41;&#44; in airways resistance &#40;p &#60; 0&#46;002&#41; and in residual volume &#40;p &#60; 0&#46;01&#41;&#59; for these same patients we recorded increases in forced vital capacity &#40;p &#60; 0&#46;04&#41; and maximum inspiratory pressure &#40;p &#60; 0&#46;02&#41;&#46; We saw no change in lung function in patients with OSAS only&#46; PaO<span class="elsevierStyleInf">2</span> increased after treatment in the 15 patients who were initially hypoxemic &#40;p &#60; 0&#46;001&#41;&#46; We conclude that after treatment with nCPAP&#44; the greatest changes in respiratory function occur in patients with both OSAS and COPD&#44; who also experience slight decrease in body weight&#46; These changes may be explained by a decrease in auto-PEEP and weight loss&#46;</p></span>"
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ISSN: 03002896
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