array:23 [
  "pii" => "S0300289615309807"
  "issn" => "03002896"
  "doi" => "10.1016/S0300-2896(15)30980-7"
  "estado" => "S300"
  "fechaPublicacion" => "1995-01-01"
  "aid" => "71050"
  "copyright" => "Sociedad Española de Neumología y Cirugía Torácica"
  "copyrightAnyo" => "1995"
  "documento" => "article"
  "crossmark" => 0
  "subdocumento" => "fla"
  "cita" => "Arch Bronconeumol. 1995;31:6-12"
  "abierto" => array:3 [
    "ES" => true
    "ES2" => true
    "LATM" => true
  ]
  "gratuito" => true
  "lecturas" => array:2 [
    "total" => 1362
    "formatos" => array:3 [
      "EPUB" => 63
      "HTML" => 654
      "PDF" => 645
    ]
  ]
  "itemSiguiente" => array:18 [
    "pii" => "S0300289615309819"
    "issn" => "03002896"
    "doi" => "10.1016/S0300-2896(15)30981-9"
    "estado" => "S300"
    "fechaPublicacion" => "1995-01-01"
    "aid" => "71051"
    "copyright" => "Sociedad Española de Neumología y Cirugía Torácica"
    "documento" => "article"
    "crossmark" => 0
    "subdocumento" => "fla"
    "cita" => "Arch Bronconeumol. 1995;31:13-7"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:2 [
      "total" => 1761
      "formatos" => array:3 [
        "EPUB" => 79
        "HTML" => 931
        "PDF" => 751
      ]
    ]
    "es" => array:10 [
      "idiomaDefecto" => true
      "titulo" => "Catéter transtraqueal y oxígeno líquido: 5 años de experiencia"
      "tienePdf" => "es"
      "tieneTextoCompleto" => 0
      "tieneResumen" => array:2 [
        0 => "es"
        1 => "en"
      ]
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "13"
          "paginaFinal" => "17"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "en" => array:1 [
          "titulo" => "Transtracheal catheter and liquid oxygen: 5 years of experience"
        ]
      ]
      "contieneResumen" => array:2 [
        "es" => true
        "en" => true
      ]
      "contienePdf" => array:1 [
        "es" => true
      ]
      "autores" => array:2 [
        0 => array:2 [
          "autoresLista" => "Ch. Domingo, J. Izquierdo, J. Roig, J. Morera"
          "autores" => array:4 [
            0 => array:2 [
              "nombre" => "Ch."
              "apellidos" => "Domingo"
            ]
            1 => array:2 [
              "nombre" => "J."
              "apellidos" => "Izquierdo"
            ]
            2 => array:2 [
              "nombre" => "J."
              "apellidos" => "Roig"
            ]
            3 => array:2 [
              "nombre" => "J."
              "apellidos" => "Morera"
            ]
          ]
        ]
        1 => array:2 [
          "autoresLista" => "R. Coll, J. Klamburg, E. Domingo, J.A. Moreno"
          "autores" => array:4 [
            0 => array:2 [
              "nombre" => "R."
              "apellidos" => "Coll"
            ]
            1 => array:2 [
              "nombre" => "J."
              "apellidos" => "Klamburg"
            ]
            2 => array:2 [
              "nombre" => "E."
              "apellidos" => "Domingo"
            ]
            3 => array:2 [
              "nombre" => "J.A."
              "apellidos" => "Moreno"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "es"
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0300289615309819?idApp=UINPBA00003Z"
    "url" => "/03002896/0000003100000001/v1_201506240021/S0300289615309819/v1_201506240021/es/main.assets"
  ]
  "itemAnterior" => array:18 [
    "pii" => "S0300289615309790"
    "issn" => "03002896"
    "doi" => "10.1016/S0300-2896(15)30979-0"
    "estado" => "S300"
    "fechaPublicacion" => "1995-01-01"
    "aid" => "71049"
    "copyright" => "Sociedad Española de Neumología y Cirugía Torácica"
    "documento" => "simple-article"
    "crossmark" => 0
    "subdocumento" => "edi"
    "cita" => "Arch Bronconeumol. 1995;31:3-5"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:2 [
      "total" => 1213
      "formatos" => array:3 [
        "EPUB" => 49
        "HTML" => 653
        "PDF" => 511
      ]
    ]
    "es" => array:7 [
      "idiomaDefecto" => true
      "titulo" => "Carcinoma broncogénico en no fumadores"
      "tienePdf" => "es"
      "tieneTextoCompleto" => 0
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "3"
          "paginaFinal" => "5"
        ]
      ]
      "contienePdf" => array:1 [
        "es" => true
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "A. López Encuentra"
          "autores" => array:1 [
            0 => array:2 [
              "nombre" => "A."
              "apellidos" => "López Encuentra"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "es"
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0300289615309790?idApp=UINPBA00003Z"
    "url" => "/03002896/0000003100000001/v1_201506240021/S0300289615309790/v1_201506240021/es/main.assets"
  ]
  "es" => array:14 [
    "idiomaDefecto" => true
    "titulo" => "Implantación, metodología y valoración de las pruebas de provocación bronquial inespecíficas en nuestro país"
    "tieneTextoCompleto" => 0
    "paginas" => array:1 [
      0 => array:2 [
        "paginaInicial" => "6"
        "paginaFinal" => "12"
      ]
    ]
    "autores" => array:1 [
      0 => array:4 [
        "autoresLista" => "C. Pellicer, B. Galdiz, M. Perpiñá, A. de Diego, V. Sobradillo"
        "autores" => array:5 [
          0 => array:3 [
            "nombre" => "C."
            "apellidos" => "Pellicer"
            "referencia" => array:2 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">a</span>"
                "identificador" => "aff0005"
              ]
              1 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">&#42;</span>"
                "identificador" => "cor0005"
              ]
            ]
          ]
          1 => array:3 [
            "nombre" => "B&#46;"
            "apellidos" => "Galdiz"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">b</span>"
                "identificador" => "aff0010"
              ]
            ]
          ]
          2 => array:3 [
            "nombre" => "M&#46;"
            "apellidos" => "Perpi&#241;&#225;"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">c</span>"
                "identificador" => "aff0015"
              ]
            ]
          ]
          3 => array:3 [
            "nombre" => "A&#46;"
            "apellidos" => "de Diego"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">c</span>"
                "identificador" => "aff0015"
              ]
            ]
          ]
          4 => array:3 [
            "nombre" => "V&#46;"
            "apellidos" => "Sobradillo"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">b</span>"
                "identificador" => "aff0010"
              ]
            ]
          ]
        ]
        "afiliaciones" => array:3 [
          0 => array:3 [
            "entidad" => "Servicios de Neumolog&#237;a&#46; Hospital Francesc de Borja&#46; Gand&#237;a"
            "etiqueta" => "a"
            "identificador" => "aff0005"
          ]
          1 => array:3 [
            "entidad" => "Servicios de Neumolog&#237;a&#46; Hospital de Cruces&#46; Bilbao"
            "etiqueta" => "b"
            "identificador" => "aff0010"
          ]
          2 => array:3 [
            "entidad" => "Servicios de Neumolog&#237;a&#46; Hospital La Fe&#46; Valencia"
            "etiqueta" => "c"
            "identificador" => "aff0015"
          ]
        ]
        "correspondencia" => array:1 [
          0 => array:3 [
            "identificador" => "cor0005"
            "etiqueta" => "&#42;"
            "correspondencia" => "Correspondencia&#58; Servicio de Neumolog&#237;a&#46; Hospital Francesc de Borja&#46; Passeig de les Germanies&#44; 71&#46; 46700 Gand&#237;a&#46; Valencia&#46;"
          ]
        ]
      ]
    ]
    "titulosAlternativos" => array:1 [
      "en" => array:1 [
        "titulo" => "Current use&#44; methodology and assessment of non-specific bronchial inhalation challenge in Spain"
      ]
    ]
    "pdfFichero" => "main.pdf"
    "tienePdf" => true
    "fechaRecibido" => "1994-04-12"
    "fechaAceptado" => "1994-07-26"
    "PalabrasClave" => array:2 [
      "es" => array:1 [
        0 => array:4 [
          "clase" => "keyword"
          "titulo" => "Palabras clave"
          "identificador" => "xpalclavsec546393"
          "palabras" => array:2 [
            0 => "Pruebas de provocaci&#243;n bronquial"
            1 => "Hiperreactividad bronquial"
          ]
        ]
      ]
      "en" => array:1 [
        0 => array:4 [
          "clase" => "keyword"
          "titulo" => "Key words"
          "identificador" => "xpalclavsec546392"
          "palabras" => array:2 [
            0 => "Bronchial inhalation challenge"
            1 => "Bronchial hyperresponsiveness"
          ]
        ]
      ]
    ]
    "tieneResumen" => true
    "resumen" => array:2 [
      "es" => array:1 [
        "resumen" => "<span id="abst0005" class="elsevierStyleSection elsevierViewall"><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Con el objeto de conocer la implantaci&#243;n de las pruebas de provocaci&#243;n bronquial &#40;PPB&#41; inespec&#237;ficas en nuestro pa&#237;s&#44; se remitieron 147 cuestionarios dirigidos a los hospitales que dispon&#237;an de servicio o unidad de neumolog&#237;a&#46; &#201;ste recog&#237;a aspectos generales t&#233;cnicos&#44; metodol&#243;gicos as&#237; como de valoraci&#243;n e interpretaci&#243;n de esta t&#233;cnica diagn&#243;stica&#46; Se recibieron 42 cuestionarios procedentes fundamentalmente de hospitales de grandes ciudades&#44; 34 de los cuales realizaban PPB&#46; El criterio m&#225;s generalizado de indicaci&#243;n de &#233;sta&#44; fue la presencia de cl&#237;nica at&#237;pica de asma &#40;33&#47;34&#41; y el est&#237;mulo m&#225;s utilizado&#44; la inhalaci&#243;n de metacolina &#40;33&#47;34&#41;&#46; Se detect&#243; una gran uniformidad en los aspectos t&#233;cnicos de preparaci&#243;n del f&#225;rmaco&#44; pero una gran heterogeneidad en cuanto a la forma de administrarlo y el protocolo seguido&#46; Del mismo modo&#44; se observ&#243; una gran diversidad en cuanto al valor de PC20&#47;PD20 indicativo de hiperreactividad bronquial&#46; Este trabajo nos aporta un mayor conocimiento de cu&#225;l es la realidad de las PPB inespec&#237;ficas en nuestro pa&#237;s&#44; destacando la necesidad de conseguir una mayor homogeneidad en la metodolog&#237;a de realizaci&#243;n&#44; que nos permita valorar e interpretar los resultados de esta t&#233;cnica diagn&#243;stica con criterios m&#225;s uniformes&#46;</p></span>"
      ]
      "en" => array:1 [
        "resumen" => "<span id="abst0010" class="elsevierStyleSection elsevierViewall"><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">With the aim of determining the current use of non-specific bronchial inhalation challenge &#40;BIC&#41; testing in Spain&#44; 147 questionnaires were sent to hospitals with pneumology departments or units&#46; The questionnaire covered general&#44; technical and methodological aspects of this diagnostic procedure&#44; as well as its assessment and interpretation&#46; Of the 42 informants who returned questionnaires&#44; mainly from large urban hospitals&#44; 34 reported using BIC&#46; The most widespread criterion applied in deciding to use BIC was the presence of atypical asthma symptoms &#40;33&#47;34&#41;&#46; The stimulus most often used was methacholine inhalation &#40;33&#47;34&#41;&#46; We found that technical preparation of the drug was highly standardized&#44; but that administration and follow-up protocols differed greatly&#46; There was also great variety in the PC20&#47;PD20 value assigned to ind&#237;cate bronchial hyperresponsiveness&#46; This study contributes to our better understanding of the current use of BIC in Spain and highlights the need to work toward greater standardization for this diagnostic procedure&#44; to enable us to assess and interpret the results more consistently&#46;</p></span>"
      ]
    ]
    "bibliografia" => array:2 [
      "titulo" => "Bibliograf&#237;a"
      "seccion" => array:1 [
        0 => array:2 [
          "identificador" => "bibs0005"
          "bibliografiaReferencia" => array:21 [
            0 => array:3 [
              "identificador" => "bib0005"
              "etiqueta" => "1&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Bronchial asthma&#58; response to pilocarpin and epinephrin"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "H&#46;L&#46; Alexander"
                            1 => "R&#46; Paddock"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Arch Intern Med"
                        "fecha" => "1921"
                        "volumen" => "27"
                        "paginaInicial" => "184"
                        "paginaFinal" => "191"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            1 => array:3 [
              "identificador" => "bib0010"
              "etiqueta" => "2&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Acetyl beta-methycholin&#46; The action on normal persons"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "I&#46; Starr"
                            1 => "K&#46;A&#46; Elsom"
                            2 => "J&#46;A&#46; Reisenger"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Am J Med Soc"
                        "fecha" => "1933"
                        "volumen" => "186"
                        "paginaInicial" => "313"
                        "paginaFinal" => "323"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            2 => array:3 [
              "identificador" => "bib0015"
              "etiqueta" => "3&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Crise d&#8217;asthme exp&#233;rimental par a&#233;rosols de carbaminoylcholine chez l&#8217;homme&#44; trait&#233;e par dispersat de ph&#233;nylaminopropane&#46; Etude de l&#8217;action sur la respiration de ces substances par la d&#233;termination du volume respiratoire utile"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "L&#46; Dautrebande"
                            1 => "E&#46; Philippot"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Presse M&#233;d"
                        "fecha" => "1941"
                        "volumen" => "49"
                        "paginaInicial" => "942"
                        "paginaFinal" => "946"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            3 => array:3 [
              "identificador" => "bib0020"
              "etiqueta" => "4&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Epreuve de bronchoconstriction et de bronchodilatation par a&#233;rosols&#46; Emploi pour le d&#233;pistage&#44; la mesure et le contr&#243;le des insufftsances respiratoires chroniques"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "R&#46; Tiffeneau"
                            1 => "M&#46; Beauvallet"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Bull Acad Med"
                        "fecha" => "1945"
                        "volumen" => "129"
                        "paginaInicial" => "165"
                        "paginaFinal" => "168"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            4 => array:3 [
              "identificador" => "bib0025"
              "etiqueta" => "5&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Methacholine aerosol as test for bronchial asthma"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "C&#46;D&#46; Parker"
                            1 => "R&#46;E&#46; Bilbo"
                            2 => "C&#46;E&#46; Read"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Arch Intern Med"
                        "fecha" => "1965"
                        "volumen" => "115"
                        "paginaInicial" => "452"
                        "paginaFinal" => "458"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/14272372"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            5 => array:3 [
              "identificador" => "bib0030"
              "etiqueta" => "6&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Bronchial hypersensitivity to mecholyl and histamine in asthmatic subjects"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "I&#46;H&#46; Itkin"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "J Allergy"
                        "fecha" => "1967"
                        "volumen" => "40"
                        "paginaInicial" => "244"
                        "paginaFinal" => "256"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            6 => array:3 [
              "identificador" => "bib0035"
              "etiqueta" => "7&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Les tests de provocation bronchique nonspecifiques dans l&#8217;asthme"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "J&#46; Orehek"
                            1 => "P&#46; Gayrard"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Bull Europ Physiopath Resp"
                        "fecha" => "1976"
                        "volumen" => "12"
                        "paginaInicial" => "65"
                        "paginaFinal" => "598"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            7 => array:3 [
              "identificador" => "bib0040"
              "etiqueta" => "8&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Standardization of bronchial inhalation challenge procedures"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "H&#46; Chai"
                            1 => "R&#46;S&#46; Farr"
                            2 => "L&#46;A&#46; Froehlich"
                            3 => "D&#46;A&#46; Mathison"
                            4 => "J&#46;A&#46; McLean"
                            5 => "R&#46; Rosenthal"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "J Allergy Clin Immunol"
                        "fecha" => "1975"
                        "volumen" => "56"
                        "paginaInicial" => "323"
                        "paginaFinal" => "327"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/1176724"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            8 => array:3 [
              "identificador" => "bib0045"
              "etiqueta" => "9&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Guidelines for bronchial inhalation challenges with pharmacologic and antigenic agents"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:7 [
                            0 => "G&#46;J&#46;A&#46; Cropp"
                            1 => "I&#46;L&#46; Berstein"
                            2 => "H&#46;A&#46; Boushey"
                            3 => "R&#46;W&#46; Hyde"
                            4 => "R&#46;R&#46; Rosenthal"
                            5 => "S&#46;H&#46; Spector"
                            6 => "R&#46;G&#46; Townley"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:4 [
                        "tituloSerie" => "ATS News"
                        "fecha" => "1980"
                        "paginaInicial" => "11"
                        "paginaFinal" => "19"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            9 => array:3 [
              "identificador" => "bib0050"
              "etiqueta" => "10&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Guidelines for standardization of bronchial challenges with &#40;nonspecific&#41; bronchoconstricting agents"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "N&#46;M&#46; Eiser"
                            1 => "K&#46;F&#46; Kerrebijn"
                            2 => "P&#46;H&#46; Quanjer"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Bull Europ Physiopath Resp"
                        "fecha" => "1983"
                        "volumen" => "19"
                        "paginaInicial" => "495"
                        "paginaFinal" => "514"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            10 => array:3 [
              "identificador" => "bib0055"
              "etiqueta" => "11&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Normativa para los tests de provocaci&#243;n bronquial inespec&#237;fica&#46; SEPAR"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "A&#46; Valencia Rodr&#237;guez"
                            1 => "P&#46; Cas&#225;n Clara"
                            2 => "M&#46; D&#237;az Fern&#225;ndez"
                            3 => "M&#46; Perpi&#241;&#225; Tordera"
                            4 => "M&#46;D&#46; Sebasti&#225;n Gil"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Libro" => array:3 [
                        "fecha" => "1987"
                        "editorial" => "Ed&#46; Doyma&#44; S&#46;A"
                        "editorialLocalizacion" => "Barcelona"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            11 => array:3 [
              "identificador" => "bib0060"
              "etiqueta" => "12&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Airway responsiveness&#46; Standardized challenge testing with pharmacological&#44; physical and sensitizing stimuli in adults"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:8 [
                            0 => "P&#46;J&#46; Sterk"
                            1 => "L&#46;M&#46; Fabbri"
                            2 => "Quanjer PhH"
                            3 => "D&#46;W&#46; Cockcroft"
                            4 => "P&#46;M&#46; O&#8217;Byrne"
                            5 => "S&#46;D&#46; Anderson"
                            6 => "E&#46;F&#46; Juniper"
                            7 => "J&#46;L&#46; Malo"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1183/09041950.053s1693"
                      "Revista" => array:6 [
                        "tituloSerie" => "Eur Respir J"
                        "fecha" => "1993"
                        "volumen" => "6"
                        "paginaInicial" => "53"
                        "paginaFinal" => "83"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/24576917"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            12 => array:3 [
              "identificador" => "bib0065"
              "etiqueta" => "13&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "A survey of the current use methods of analysis of bronchoprovocational challenges"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "G&#46;C&#46; Scott"
                            1 => "S&#46;H&#46; Braun"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Chest"
                        "fecha" => "1991"
                        "volumen" => "100"
                        "paginaInicial" => "322"
                        "paginaFinal" => "328"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/1864101"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            13 => array:3 [
              "identificador" => "bib0070"
              "etiqueta" => "14&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Bronchoprovocation committee report"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "G&#46;G&#46; Shapiro"
                            1 => "R&#46;A&#46; Sinon"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "J Allergy Clin Immunol"
                        "fecha" => "1992"
                        "volumen" => "89"
                        "paginaInicial" => "775"
                        "paginaFinal" => "778"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/1545099"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            14 => array:3 [
              "identificador" => "bib0075"
              "etiqueta" => "15&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Prueba de provocaci&#243;n farmacol&#243;gica bronquial"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "C&#46; Pellicer Ciscar"
                            1 => "J&#46; Sanch&#237;s Aldas"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "LibroEditado" => array:4 [
                        "titulo" => "Hiperreactividad bronquial inespec&#237;fica"
                        "paginaInicial" => "99"
                        "paginaFinal" => "115"
                        "serieFecha" => "1993"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            15 => array:3 [
              "identificador" => "bib0080"
              "etiqueta" => "16&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Hiperreactividad bronquial concepto y consideraciones generales"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "M&#46; Perpi&#241;&#225; Tordera"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "LibroEditado" => array:4 [
                        "titulo" => "Hiperreactividad bronquial inespec&#237;fica"
                        "paginaInicial" => "1"
                        "paginaFinal" => "14"
                        "serieFecha" => "1993"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            16 => array:3 [
              "identificador" => "bib0085"
              "etiqueta" => "17&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Bronchial reactivity to inhaled histamine&#58; a method and clinical survey"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "D&#46;W&#46; Cockcroft"
                            1 => "D&#46;N&#46; Killian"
                            2 => "J&#46;J&#46;A&#46; Mellon"
                            3 => "F&#46;E&#46; Hargreave"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Clin Allergy"
                        "fecha" => "1977"
                        "volumen" => "7"
                        "paginaInicial" => "235"
                        "paginaFinal" => "243"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/908121"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            17 => array:3 [
              "identificador" => "bib0090"
              "etiqueta" => "18&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Standardization of inhalation provocation tests&#58; influence of nebulizer output&#44; particle size&#44; and method of inhalation"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:8 [
                            0 => "G&#46; Ryan"
                            1 => "M&#46;B&#46; Dolovich"
                            2 => "P&#46; Eng"
                            3 => "G&#46; Obminski"
                            4 => "D&#46;W&#46; Cockcroft"
                            5 => "E&#46; Juniper"
                            6 => "F&#46;E&#46; Hargreave"
                            7 => "M&#46;T&#46; Newhouse"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "J Allergy Clin Immunol"
                        "fecha" => "1981"
                        "volumen" => "67"
                        "paginaInicial" => "156"
                        "paginaFinal" => "161"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/7451782"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            18 => array:3 [
              "identificador" => "bib0095"
              "etiqueta" => "19&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "The physical properties of a jet-nebulizer and their relevance for the histamine provocation test"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "P&#46;J&#46; Sterk"
                            1 => "A&#46; Plomp"
                            2 => "M&#46;J&#46;J&#46;S&#46; Crobach"
                            3 => "J&#46;F&#46; Van de Vate"
                            4 => "PhH&#46; Quanjer"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Bull Europ Physiopathol Respir"
                        "fecha" => "1983"
                        "volumen" => "19"
                        "paginaInicial" => "27"
                        "paginaFinal" => "36"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            19 => array:3 [
              "identificador" => "bib0100"
              "etiqueta" => "20&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Physical properties of aerosols produced by several jet and ultrasonic nebulizers"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "P&#46;J&#46; Sterk"
                            1 => "A&#46; Plomp"
                            2 => "J&#46;F&#46; Van de Vate"
                            3 => "PhH&#46; Quanjer"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Bull Eur Physiopathol Respir"
                        "fecha" => "1984"
                        "volumen" => "20"
                        "paginaInicial" => "65"
                        "paginaFinal" => "72"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/6704568"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            20 => array:3 [
              "identificador" => "bib0105"
              "etiqueta" => "21&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Technical factors influencing response to challenge aerosols"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "M&#46;B&#46; Dolovich"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "LibroEditado" => array:4 [
                        "titulo" => "Airway Responsiveness&#46; Measurement and interpretation"
                        "paginaInicial" => "9"
                        "paginaFinal" => "21"
                        "serieFecha" => "1985"
                      ]
                    ]
                  ]
                ]
              ]
            ]
          ]
        ]
      ]
    ]
  ]
  "idiomaDefecto" => "es"
  "url" => "/03002896/0000003100000001/v1_201506240021/S0300289615309807/v1_201506240021/es/main.assets"
  "Apartado" => array:4 [
    "identificador" => "9277"
    "tipo" => "SECCION"
    "en" => array:2 [
      "titulo" => "Originales"
      "idiomaDefecto" => true
    ]
    "idiomaDefecto" => "en"
  ]
  "PDF" => "https://static.elsevier.es/multimedia/03002896/0000003100000001/v1_201506240021/S0300289615309807/v1_201506240021/es/main.pdf?idApp=UINPBA00003Z&text.app=https://archbronconeumol.org/"
  "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0300289615309807?idApp=UINPBA00003Z"
]
Share
Journal Information

Statistics

Follow this link to access the full text of the article

Implantación, metodología y valoración de las pruebas de provocación bronquial inespecíficas en nuestro país
Current use, methodology and assessment of non-specific bronchial inhalation challenge in Spain
C. Pellicera,*, B. Galdizb, M. Perpiñác, A. de Diegoc, V. Sobradillob
a Servicios de Neumología. Hospital Francesc de Borja. Gandía
b Servicios de Neumología. Hospital de Cruces. Bilbao
c Servicios de Neumología. Hospital La Fe. Valencia
Read
3738
Times
was read the article
1786
Total PDF
1952
Total HTML
Share statistics
 array:23 [
  "pii" => "S0300289615309807"
  "issn" => "03002896"
  "doi" => "10.1016/S0300-2896(15)30980-7"
  "estado" => "S300"
  "fechaPublicacion" => "1995-01-01"
  "aid" => "71050"
  "copyright" => "Sociedad Espa&#241;ola de Neumolog&#237;a y Cirug&#237;a Tor&#225;cica"
  "copyrightAnyo" => "1995"
  "documento" => "article"
  "crossmark" => 0
  "subdocumento" => "fla"
  "cita" => "Arch Bronconeumol. 1995;31:6-12"
  "abierto" => array:3 [
    "ES" => true
    "ES2" => true
    "LATM" => true
  ]
  "gratuito" => true
  "lecturas" => array:2 [
    "total" => 1362
    "formatos" => array:3 [
      "EPUB" => 63
      "HTML" => 654
      "PDF" => 645
    ]
  ]
  "itemSiguiente" => array:18 [
    "pii" => "S0300289615309819"
    "issn" => "03002896"
    "doi" => "10.1016/S0300-2896(15)30981-9"
    "estado" => "S300"
    "fechaPublicacion" => "1995-01-01"
    "aid" => "71051"
    "copyright" => "Sociedad Espa&#241;ola de Neumolog&#237;a y Cirug&#237;a Tor&#225;cica"
    "documento" => "article"
    "crossmark" => 0
    "subdocumento" => "fla"
    "cita" => "Arch Bronconeumol. 1995;31:13-7"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:2 [
      "total" => 1761
      "formatos" => array:3 [
        "EPUB" => 79
        "HTML" => 931
        "PDF" => 751
      ]
    ]
    "es" => array:10 [
      "idiomaDefecto" => true
      "titulo" => "Cat&#233;ter transtraqueal y ox&#237;geno l&#237;quido&#58; 5 a&#241;os de experiencia"
      "tienePdf" => "es"
      "tieneTextoCompleto" => 0
      "tieneResumen" => array:2 [
        0 => "es"
        1 => "en"
      ]
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "13"
          "paginaFinal" => "17"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "en" => array:1 [
          "titulo" => "Transtracheal catheter and liquid oxygen&#58; 5 years of experience"
        ]
      ]
      "contieneResumen" => array:2 [
        "es" => true
        "en" => true
      ]
      "contienePdf" => array:1 [
        "es" => true
      ]
      "autores" => array:2 [
        0 => array:2 [
          "autoresLista" => "Ch&#46; Domingo, J&#46; Izquierdo, J&#46; Roig, J&#46; Morera"
          "autores" => array:4 [
            0 => array:2 [
              "nombre" => "Ch&#46;"
              "apellidos" => "Domingo"
            ]
            1 => array:2 [
              "nombre" => "J&#46;"
              "apellidos" => "Izquierdo"
            ]
            2 => array:2 [
              "nombre" => "J&#46;"
              "apellidos" => "Roig"
            ]
            3 => array:2 [
              "nombre" => "J&#46;"
              "apellidos" => "Morera"
            ]
          ]
        ]
        1 => array:2 [
          "autoresLista" => "R&#46; Coll, J&#46; Klamburg, E&#46; Domingo, J&#46;A&#46; Moreno"
          "autores" => array:4 [
            0 => array:2 [
              "nombre" => "R&#46;"
              "apellidos" => "Coll"
            ]
            1 => array:2 [
              "nombre" => "J&#46;"
              "apellidos" => "Klamburg"
            ]
            2 => array:2 [
              "nombre" => "E&#46;"
              "apellidos" => "Domingo"
            ]
            3 => array:2 [
              "nombre" => "J&#46;A&#46;"
              "apellidos" => "Moreno"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "es"
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0300289615309819?idApp=UINPBA00003Z"
    "url" => "/03002896/0000003100000001/v1_201506240021/S0300289615309819/v1_201506240021/es/main.assets"
  ]
  "itemAnterior" => array:18 [
    "pii" => "S0300289615309790"
    "issn" => "03002896"
    "doi" => "10.1016/S0300-2896(15)30979-0"
    "estado" => "S300"
    "fechaPublicacion" => "1995-01-01"
    "aid" => "71049"
    "copyright" => "Sociedad Espa&#241;ola de Neumolog&#237;a y Cirug&#237;a Tor&#225;cica"
    "documento" => "simple-article"
    "crossmark" => 0
    "subdocumento" => "edi"
    "cita" => "Arch Bronconeumol. 1995;31:3-5"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:2 [
      "total" => 1213
      "formatos" => array:3 [
        "EPUB" => 49
        "HTML" => 653
        "PDF" => 511
      ]
    ]
    "es" => array:7 [
      "idiomaDefecto" => true
      "titulo" => "Carcinoma broncog&#233;nico en no fumadores"
      "tienePdf" => "es"
      "tieneTextoCompleto" => 0
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "3"
          "paginaFinal" => "5"
        ]
      ]
      "contienePdf" => array:1 [
        "es" => true
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "A&#46; L&#243;pez Encuentra"
          "autores" => array:1 [
            0 => array:2 [
              "nombre" => "A&#46;"
              "apellidos" => "L&#243;pez Encuentra"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "es"
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0300289615309790?idApp=UINPBA00003Z"
    "url" => "/03002896/0000003100000001/v1_201506240021/S0300289615309790/v1_201506240021/es/main.assets"
  ]
  "es" => array:14 [
    "idiomaDefecto" => true
    "titulo" => "Implantaci&#243;n&#44; metodolog&#237;a y valoraci&#243;n de las pruebas de provocaci&#243;n bronquial inespec&#237;ficas en nuestro pa&#237;s"
    "tieneTextoCompleto" => 0
    "paginas" => array:1 [
      0 => array:2 [
        "paginaInicial" => "6"
        "paginaFinal" => "12"
      ]
    ]
    "autores" => array:1 [
      0 => array:4 [
        "autoresLista" => "C&#46; Pellicer, B&#46; Galdiz, M&#46; Perpi&#241;&#225;, A&#46; de Diego, V&#46; Sobradillo"
        "autores" => array:5 [
          0 => array:3 [
            "nombre" => "C&#46;"
            "apellidos" => "Pellicer"
            "referencia" => array:2 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">a</span>"
                "identificador" => "aff0005"
              ]
              1 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">&#42;</span>"
                "identificador" => "cor0005"
              ]
            ]
          ]
          1 => array:3 [
            "nombre" => "B&#46;"
            "apellidos" => "Galdiz"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">b</span>"
                "identificador" => "aff0010"
              ]
            ]
          ]
          2 => array:3 [
            "nombre" => "M&#46;"
            "apellidos" => "Perpi&#241;&#225;"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">c</span>"
                "identificador" => "aff0015"
              ]
            ]
          ]
          3 => array:3 [
            "nombre" => "A&#46;"
            "apellidos" => "de Diego"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">c</span>"
                "identificador" => "aff0015"
              ]
            ]
          ]
          4 => array:3 [
            "nombre" => "V&#46;"
            "apellidos" => "Sobradillo"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">b</span>"
                "identificador" => "aff0010"
              ]
            ]
          ]
        ]
        "afiliaciones" => array:3 [
          0 => array:3 [
            "entidad" => "Servicios de Neumolog&#237;a&#46; Hospital Francesc de Borja&#46; Gand&#237;a"
            "etiqueta" => "a"
            "identificador" => "aff0005"
          ]
          1 => array:3 [
            "entidad" => "Servicios de Neumolog&#237;a&#46; Hospital de Cruces&#46; Bilbao"
            "etiqueta" => "b"
            "identificador" => "aff0010"
          ]
          2 => array:3 [
            "entidad" => "Servicios de Neumolog&#237;a&#46; Hospital La Fe&#46; Valencia"
            "etiqueta" => "c"
            "identificador" => "aff0015"
          ]
        ]
        "correspondencia" => array:1 [
          0 => array:3 [
            "identificador" => "cor0005"
            "etiqueta" => "&#42;"
            "correspondencia" => "Correspondencia&#58; Servicio de Neumolog&#237;a&#46; Hospital Francesc de Borja&#46; Passeig de les Germanies&#44; 71&#46; 46700 Gand&#237;a&#46; Valencia&#46;"
          ]
        ]
      ]
    ]
    "titulosAlternativos" => array:1 [
      "en" => array:1 [
        "titulo" => "Current use&#44; methodology and assessment of non-specific bronchial inhalation challenge in Spain"
      ]
    ]
    "pdfFichero" => "main.pdf"
    "tienePdf" => true
    "fechaRecibido" => "1994-04-12"
    "fechaAceptado" => "1994-07-26"
    "PalabrasClave" => array:2 [
      "es" => array:1 [
        0 => array:4 [
          "clase" => "keyword"
          "titulo" => "Palabras clave"
          "identificador" => "xpalclavsec546393"
          "palabras" => array:2 [
            0 => "Pruebas de provocaci&#243;n bronquial"
            1 => "Hiperreactividad bronquial"
          ]
        ]
      ]
      "en" => array:1 [
        0 => array:4 [
          "clase" => "keyword"
          "titulo" => "Key words"
          "identificador" => "xpalclavsec546392"
          "palabras" => array:2 [
            0 => "Bronchial inhalation challenge"
            1 => "Bronchial hyperresponsiveness"
          ]
        ]
      ]
    ]
    "tieneResumen" => true
    "resumen" => array:2 [
      "es" => array:1 [
        "resumen" => "<span id="abst0005" class="elsevierStyleSection elsevierViewall"><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Con el objeto de conocer la implantaci&#243;n de las pruebas de provocaci&#243;n bronquial &#40;PPB&#41; inespec&#237;ficas en nuestro pa&#237;s&#44; se remitieron 147 cuestionarios dirigidos a los hospitales que dispon&#237;an de servicio o unidad de neumolog&#237;a&#46; &#201;ste recog&#237;a aspectos generales t&#233;cnicos&#44; metodol&#243;gicos as&#237; como de valoraci&#243;n e interpretaci&#243;n de esta t&#233;cnica diagn&#243;stica&#46; Se recibieron 42 cuestionarios procedentes fundamentalmente de hospitales de grandes ciudades&#44; 34 de los cuales realizaban PPB&#46; El criterio m&#225;s generalizado de indicaci&#243;n de &#233;sta&#44; fue la presencia de cl&#237;nica at&#237;pica de asma &#40;33&#47;34&#41; y el est&#237;mulo m&#225;s utilizado&#44; la inhalaci&#243;n de metacolina &#40;33&#47;34&#41;&#46; Se detect&#243; una gran uniformidad en los aspectos t&#233;cnicos de preparaci&#243;n del f&#225;rmaco&#44; pero una gran heterogeneidad en cuanto a la forma de administrarlo y el protocolo seguido&#46; Del mismo modo&#44; se observ&#243; una gran diversidad en cuanto al valor de PC20&#47;PD20 indicativo de hiperreactividad bronquial&#46; Este trabajo nos aporta un mayor conocimiento de cu&#225;l es la realidad de las PPB inespec&#237;ficas en nuestro pa&#237;s&#44; destacando la necesidad de conseguir una mayor homogeneidad en la metodolog&#237;a de realizaci&#243;n&#44; que nos permita valorar e interpretar los resultados de esta t&#233;cnica diagn&#243;stica con criterios m&#225;s uniformes&#46;</p></span>"
      ]
      "en" => array:1 [
        "resumen" => "<span id="abst0010" class="elsevierStyleSection elsevierViewall"><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">With the aim of determining the current use of non-specific bronchial inhalation challenge &#40;BIC&#41; testing in Spain&#44; 147 questionnaires were sent to hospitals with pneumology departments or units&#46; The questionnaire covered general&#44; technical and methodological aspects of this diagnostic procedure&#44; as well as its assessment and interpretation&#46; Of the 42 informants who returned questionnaires&#44; mainly from large urban hospitals&#44; 34 reported using BIC&#46; The most widespread criterion applied in deciding to use BIC was the presence of atypical asthma symptoms &#40;33&#47;34&#41;&#46; The stimulus most often used was methacholine inhalation &#40;33&#47;34&#41;&#46; We found that technical preparation of the drug was highly standardized&#44; but that administration and follow-up protocols differed greatly&#46; There was also great variety in the PC20&#47;PD20 value assigned to ind&#237;cate bronchial hyperresponsiveness&#46; This study contributes to our better understanding of the current use of BIC in Spain and highlights the need to work toward greater standardization for this diagnostic procedure&#44; to enable us to assess and interpret the results more consistently&#46;</p></span>"
      ]
    ]
    "bibliografia" => array:2 [
      "titulo" => "Bibliograf&#237;a"
      "seccion" => array:1 [
        0 => array:2 [
          "identificador" => "bibs0005"
          "bibliografiaReferencia" => array:21 [
            0 => array:3 [
              "identificador" => "bib0005"
              "etiqueta" => "1&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Bronchial asthma&#58; response to pilocarpin and epinephrin"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "H&#46;L&#46; Alexander"
                            1 => "R&#46; Paddock"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Arch Intern Med"
                        "fecha" => "1921"
                        "volumen" => "27"
                        "paginaInicial" => "184"
                        "paginaFinal" => "191"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            1 => array:3 [
              "identificador" => "bib0010"
              "etiqueta" => "2&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Acetyl beta-methycholin&#46; The action on normal persons"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "I&#46; Starr"
                            1 => "K&#46;A&#46; Elsom"
                            2 => "J&#46;A&#46; Reisenger"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Am J Med Soc"
                        "fecha" => "1933"
                        "volumen" => "186"
                        "paginaInicial" => "313"
                        "paginaFinal" => "323"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            2 => array:3 [
              "identificador" => "bib0015"
              "etiqueta" => "3&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Crise d&#8217;asthme exp&#233;rimental par a&#233;rosols de carbaminoylcholine chez l&#8217;homme&#44; trait&#233;e par dispersat de ph&#233;nylaminopropane&#46; Etude de l&#8217;action sur la respiration de ces substances par la d&#233;termination du volume respiratoire utile"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "L&#46; Dautrebande"
                            1 => "E&#46; Philippot"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Presse M&#233;d"
                        "fecha" => "1941"
                        "volumen" => "49"
                        "paginaInicial" => "942"
                        "paginaFinal" => "946"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            3 => array:3 [
              "identificador" => "bib0020"
              "etiqueta" => "4&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Epreuve de bronchoconstriction et de bronchodilatation par a&#233;rosols&#46; Emploi pour le d&#233;pistage&#44; la mesure et le contr&#243;le des insufftsances respiratoires chroniques"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "R&#46; Tiffeneau"
                            1 => "M&#46; Beauvallet"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Bull Acad Med"
                        "fecha" => "1945"
                        "volumen" => "129"
                        "paginaInicial" => "165"
                        "paginaFinal" => "168"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            4 => array:3 [
              "identificador" => "bib0025"
              "etiqueta" => "5&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Methacholine aerosol as test for bronchial asthma"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "C&#46;D&#46; Parker"
                            1 => "R&#46;E&#46; Bilbo"
                            2 => "C&#46;E&#46; Read"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Arch Intern Med"
                        "fecha" => "1965"
                        "volumen" => "115"
                        "paginaInicial" => "452"
                        "paginaFinal" => "458"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/14272372"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            5 => array:3 [
              "identificador" => "bib0030"
              "etiqueta" => "6&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Bronchial hypersensitivity to mecholyl and histamine in asthmatic subjects"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "I&#46;H&#46; Itkin"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "J Allergy"
                        "fecha" => "1967"
                        "volumen" => "40"
                        "paginaInicial" => "244"
                        "paginaFinal" => "256"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            6 => array:3 [
              "identificador" => "bib0035"
              "etiqueta" => "7&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Les tests de provocation bronchique nonspecifiques dans l&#8217;asthme"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "J&#46; Orehek"
                            1 => "P&#46; Gayrard"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Bull Europ Physiopath Resp"
                        "fecha" => "1976"
                        "volumen" => "12"
                        "paginaInicial" => "65"
                        "paginaFinal" => "598"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            7 => array:3 [
              "identificador" => "bib0040"
              "etiqueta" => "8&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Standardization of bronchial inhalation challenge procedures"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "H&#46; Chai"
                            1 => "R&#46;S&#46; Farr"
                            2 => "L&#46;A&#46; Froehlich"
                            3 => "D&#46;A&#46; Mathison"
                            4 => "J&#46;A&#46; McLean"
                            5 => "R&#46; Rosenthal"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "J Allergy Clin Immunol"
                        "fecha" => "1975"
                        "volumen" => "56"
                        "paginaInicial" => "323"
                        "paginaFinal" => "327"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/1176724"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            8 => array:3 [
              "identificador" => "bib0045"
              "etiqueta" => "9&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Guidelines for bronchial inhalation challenges with pharmacologic and antigenic agents"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:7 [
                            0 => "G&#46;J&#46;A&#46; Cropp"
                            1 => "I&#46;L&#46; Berstein"
                            2 => "H&#46;A&#46; Boushey"
                            3 => "R&#46;W&#46; Hyde"
                            4 => "R&#46;R&#46; Rosenthal"
                            5 => "S&#46;H&#46; Spector"
                            6 => "R&#46;G&#46; Townley"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:4 [
                        "tituloSerie" => "ATS News"
                        "fecha" => "1980"
                        "paginaInicial" => "11"
                        "paginaFinal" => "19"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            9 => array:3 [
              "identificador" => "bib0050"
              "etiqueta" => "10&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Guidelines for standardization of bronchial challenges with &#40;nonspecific&#41; bronchoconstricting agents"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "N&#46;M&#46; Eiser"
                            1 => "K&#46;F&#46; Kerrebijn"
                            2 => "P&#46;H&#46; Quanjer"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Bull Europ Physiopath Resp"
                        "fecha" => "1983"
                        "volumen" => "19"
                        "paginaInicial" => "495"
                        "paginaFinal" => "514"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            10 => array:3 [
              "identificador" => "bib0055"
              "etiqueta" => "11&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Normativa para los tests de provocaci&#243;n bronquial inespec&#237;fica&#46; SEPAR"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "A&#46; Valencia Rodr&#237;guez"
                            1 => "P&#46; Cas&#225;n Clara"
                            2 => "M&#46; D&#237;az Fern&#225;ndez"
                            3 => "M&#46; Perpi&#241;&#225; Tordera"
                            4 => "M&#46;D&#46; Sebasti&#225;n Gil"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Libro" => array:3 [
                        "fecha" => "1987"
                        "editorial" => "Ed&#46; Doyma&#44; S&#46;A"
                        "editorialLocalizacion" => "Barcelona"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            11 => array:3 [
              "identificador" => "bib0060"
              "etiqueta" => "12&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Airway responsiveness&#46; Standardized challenge testing with pharmacological&#44; physical and sensitizing stimuli in adults"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:8 [
                            0 => "P&#46;J&#46; Sterk"
                            1 => "L&#46;M&#46; Fabbri"
                            2 => "Quanjer PhH"
                            3 => "D&#46;W&#46; Cockcroft"
                            4 => "P&#46;M&#46; O&#8217;Byrne"
                            5 => "S&#46;D&#46; Anderson"
                            6 => "E&#46;F&#46; Juniper"
                            7 => "J&#46;L&#46; Malo"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1183/09041950.053s1693"
                      "Revista" => array:6 [
                        "tituloSerie" => "Eur Respir J"
                        "fecha" => "1993"
                        "volumen" => "6"
                        "paginaInicial" => "53"
                        "paginaFinal" => "83"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/24576917"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            12 => array:3 [
              "identificador" => "bib0065"
              "etiqueta" => "13&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "A survey of the current use methods of analysis of bronchoprovocational challenges"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "G&#46;C&#46; Scott"
                            1 => "S&#46;H&#46; Braun"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Chest"
                        "fecha" => "1991"
                        "volumen" => "100"
                        "paginaInicial" => "322"
                        "paginaFinal" => "328"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/1864101"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            13 => array:3 [
              "identificador" => "bib0070"
              "etiqueta" => "14&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Bronchoprovocation committee report"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "G&#46;G&#46; Shapiro"
                            1 => "R&#46;A&#46; Sinon"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "J Allergy Clin Immunol"
                        "fecha" => "1992"
                        "volumen" => "89"
                        "paginaInicial" => "775"
                        "paginaFinal" => "778"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/1545099"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            14 => array:3 [
              "identificador" => "bib0075"
              "etiqueta" => "15&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Prueba de provocaci&#243;n farmacol&#243;gica bronquial"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "C&#46; Pellicer Ciscar"
                            1 => "J&#46; Sanch&#237;s Aldas"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "LibroEditado" => array:4 [
                        "titulo" => "Hiperreactividad bronquial inespec&#237;fica"
                        "paginaInicial" => "99"
                        "paginaFinal" => "115"
                        "serieFecha" => "1993"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            15 => array:3 [
              "identificador" => "bib0080"
              "etiqueta" => "16&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Hiperreactividad bronquial concepto y consideraciones generales"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "M&#46; Perpi&#241;&#225; Tordera"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "LibroEditado" => array:4 [
                        "titulo" => "Hiperreactividad bronquial inespec&#237;fica"
                        "paginaInicial" => "1"
                        "paginaFinal" => "14"
                        "serieFecha" => "1993"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            16 => array:3 [
              "identificador" => "bib0085"
              "etiqueta" => "17&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Bronchial reactivity to inhaled histamine&#58; a method and clinical survey"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "D&#46;W&#46; Cockcroft"
                            1 => "D&#46;N&#46; Killian"
                            2 => "J&#46;J&#46;A&#46; Mellon"
                            3 => "F&#46;E&#46; Hargreave"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Clin Allergy"
                        "fecha" => "1977"
                        "volumen" => "7"
                        "paginaInicial" => "235"
                        "paginaFinal" => "243"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/908121"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            17 => array:3 [
              "identificador" => "bib0090"
              "etiqueta" => "18&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Standardization of inhalation provocation tests&#58; influence of nebulizer output&#44; particle size&#44; and method of inhalation"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:8 [
                            0 => "G&#46; Ryan"
                            1 => "M&#46;B&#46; Dolovich"
                            2 => "P&#46; Eng"
                            3 => "G&#46; Obminski"
                            4 => "D&#46;W&#46; Cockcroft"
                            5 => "E&#46; Juniper"
                            6 => "F&#46;E&#46; Hargreave"
                            7 => "M&#46;T&#46; Newhouse"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "J Allergy Clin Immunol"
                        "fecha" => "1981"
                        "volumen" => "67"
                        "paginaInicial" => "156"
                        "paginaFinal" => "161"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/7451782"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            18 => array:3 [
              "identificador" => "bib0095"
              "etiqueta" => "19&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "The physical properties of a jet-nebulizer and their relevance for the histamine provocation test"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "P&#46;J&#46; Sterk"
                            1 => "A&#46; Plomp"
                            2 => "M&#46;J&#46;J&#46;S&#46; Crobach"
                            3 => "J&#46;F&#46; Van de Vate"
                            4 => "PhH&#46; Quanjer"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Bull Europ Physiopathol Respir"
                        "fecha" => "1983"
                        "volumen" => "19"
                        "paginaInicial" => "27"
                        "paginaFinal" => "36"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            19 => array:3 [
              "identificador" => "bib0100"
              "etiqueta" => "20&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Physical properties of aerosols produced by several jet and ultrasonic nebulizers"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "P&#46;J&#46; Sterk"
                            1 => "A&#46; Plomp"
                            2 => "J&#46;F&#46; Van de Vate"
                            3 => "PhH&#46; Quanjer"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Bull Eur Physiopathol Respir"
                        "fecha" => "1984"
                        "volumen" => "20"
                        "paginaInicial" => "65"
                        "paginaFinal" => "72"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/6704568"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            20 => array:3 [
              "identificador" => "bib0105"
              "etiqueta" => "21&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Technical factors influencing response to challenge aerosols"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "M&#46;B&#46; Dolovich"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "LibroEditado" => array:4 [
                        "titulo" => "Airway Responsiveness&#46; Measurement and interpretation"
                        "paginaInicial" => "9"
                        "paginaFinal" => "21"
                        "serieFecha" => "1985"
                      ]
                    ]
                  ]
                ]
              ]
            ]
          ]
        ]
      ]
    ]
  ]
  "idiomaDefecto" => "es"
  "url" => "/03002896/0000003100000001/v1_201506240021/S0300289615309807/v1_201506240021/es/main.assets"
  "Apartado" => array:4 [
    "identificador" => "9277"
    "tipo" => "SECCION"
    "en" => array:2 [
      "titulo" => "Originales"
      "idiomaDefecto" => true
    ]
    "idiomaDefecto" => "en"
  ]
  "PDF" => "https://static.elsevier.es/multimedia/03002896/0000003100000001/v1_201506240021/S0300289615309807/v1_201506240021/es/main.pdf?idApp=UINPBA00003Z&text.app=https://archbronconeumol.org/"
  "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0300289615309807?idApp=UINPBA00003Z"
]
Article information
ISSN: 03002896
Original language: Spanish
The statistics are updated each day
Year/Month Html Pdf Total
2024 November 3 4 7
2024 October 35 12 47
2024 September 37 15 52
2024 August 48 32 80
2024 July 40 26 66
2024 June 69 32 101
2024 May 41 31 72
2024 April 34 24 58
2024 March 39 27 66
2024 February 34 43 77
2024 January 0 1 1
2023 December 0 5 5
2023 November 0 2 2
2023 October 0 4 4
2023 September 0 1 1
2023 August 0 1 1
2023 July 0 2 2
2023 June 0 2 2
2023 March 6 3 9
2023 February 31 27 58
2023 January 30 39 69
2022 December 53 26 79
2022 November 45 17 62
2022 October 33 31 64
2022 September 27 21 48
2022 August 39 39 78
2022 July 26 35 61
2022 June 22 28 50
2022 May 34 31 65
2022 April 44 29 73
2022 March 35 39 74
2022 February 29 20 49
2022 January 31 32 63
2021 December 14 38 52
2021 November 21 31 52
2021 October 19 40 59
2021 September 18 33 51
2021 August 22 31 53
2021 July 22 26 48
2021 June 18 35 53
2021 May 14 28 42
2021 April 15 28 43
2021 March 25 9 34
2021 February 20 14 34
2021 January 14 14 28
2020 December 18 16 34
2020 November 15 13 28
2020 October 22 9 31
2020 September 16 13 29
2020 August 20 7 27
2020 July 32 19 51
2020 June 18 10 28
2020 May 23 10 33
2020 April 24 13 37
2020 March 15 17 32
2020 February 18 17 35
2020 January 25 24 49
2019 December 22 14 36
2019 November 7 15 22
2019 October 25 9 34
2019 September 13 40 53
2019 August 6 4 10
2019 July 12 24 36
2019 June 8 23 31
2019 May 12 40 52
2019 April 26 64 90
2019 March 12 29 41
2019 February 8 11 19
2019 January 5 8 13
2018 December 4 15 19
2018 November 16 18 34
2018 October 31 12 43
2018 September 13 6 19
2018 May 3 1 4
2018 April 3 7 10
2018 March 11 10 21
2018 February 9 10 19
2018 January 7 6 13
2017 December 9 13 22
2017 November 6 6 12
2017 October 5 17 22
2017 September 7 10 17
2017 August 11 10 21
2017 July 4 5 9
2017 June 15 17 32
2017 May 13 9 22
2017 April 4 5 9
2017 March 4 6 10
2017 February 2 9 11
2017 January 9 11 20
2016 December 13 5 18
2016 November 23 11 34
2016 October 29 24 53
2016 September 26 13 39
2016 August 17 7 24
2016 July 18 7 25
2016 June 17 7 24
2016 May 17 4 21
2016 April 8 0 8
2016 March 5 0 5
2016 February 13 1 14
2016 January 28 15 43
2015 December 25 20 45
2015 November 30 10 40
2015 October 6 2 8
2015 September 1 0 1
2015 June 1 0 1
Show all

Follow this link to access the full text of the article

Archivos de Bronconeumología

Are you a health professional able to prescribe or dispense drugs?