Implantación, metodología y valoración de las pruebas de provocación bronquial inespecíficas en nuestro país
Current use, methodology and assessment of non-specific bronchial inhalation challenge in Spain
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López Encuentra" "autores" => array:1 [ 0 => array:2 [ "nombre" => "A." "apellidos" => "López Encuentra" ] ] ] ] ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0300289615309790?idApp=UINPBA00003Z" "url" => "/03002896/0000003100000001/v1_201506240021/S0300289615309790/v1_201506240021/es/main.assets" ] "es" => array:14 [ "idiomaDefecto" => true "titulo" => "Implantación, metodología y valoración de las pruebas de provocación bronquial inespecíficas en nuestro país" "tieneTextoCompleto" => 0 "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "6" "paginaFinal" => "12" ] ] "autores" => array:1 [ 0 => array:4 [ "autoresLista" => "C. Pellicer, B. Galdiz, M. Perpiñá, A. de Diego, V. Sobradillo" "autores" => array:5 [ 0 => array:3 [ "nombre" => "C." "apellidos" => "Pellicer" "referencia" => array:2 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] 1 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">*</span>" "identificador" => "cor0005" ] ] ] 1 => array:3 [ "nombre" => "B." "apellidos" => "Galdiz" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff0010" ] ] ] 2 => array:3 [ "nombre" => "M." "apellidos" => "Perpiñá" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">c</span>" "identificador" => "aff0015" ] ] ] 3 => array:3 [ "nombre" => "A." "apellidos" => "de Diego" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">c</span>" "identificador" => "aff0015" ] ] ] 4 => array:3 [ "nombre" => "V." "apellidos" => "Sobradillo" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff0010" ] ] ] ] "afiliaciones" => array:3 [ 0 => array:3 [ "entidad" => "Servicios de Neumología. Hospital Francesc de Borja. Gandía" "etiqueta" => "a" "identificador" => "aff0005" ] 1 => array:3 [ "entidad" => "Servicios de Neumología. Hospital de Cruces. Bilbao" "etiqueta" => "b" "identificador" => "aff0010" ] 2 => array:3 [ "entidad" => "Servicios de Neumología. Hospital La Fe. Valencia" "etiqueta" => "c" "identificador" => "aff0015" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "*" "correspondencia" => "Correspondencia: Servicio de Neumología. Hospital Francesc de Borja. Passeig de les Germanies, 71. 46700 Gandía. Valencia." ] ] ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Current use, methodology and assessment of non-specific bronchial inhalation challenge in Spain" ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "1994-04-12" "fechaAceptado" => "1994-07-26" "PalabrasClave" => array:2 [ "es" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palabras clave" "identificador" => "xpalclavsec546393" "palabras" => array:2 [ 0 => "Pruebas de provocación bronquial" 1 => "Hiperreactividad bronquial" ] ] ] "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Key words" "identificador" => "xpalclavsec546392" "palabras" => array:2 [ 0 => "Bronchial inhalation challenge" 1 => "Bronchial hyperresponsiveness" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "es" => array:1 [ "resumen" => "<span id="abst0005" class="elsevierStyleSection elsevierViewall"><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Con el objeto de conocer la implantación de las pruebas de provocación bronquial (PPB) inespecíficas en nuestro país, se remitieron 147 cuestionarios dirigidos a los hospitales que disponían de servicio o unidad de neumología. Éste recogía aspectos generales técnicos, metodológicos así como de valoración e interpretación de esta técnica diagnóstica. Se recibieron 42 cuestionarios procedentes fundamentalmente de hospitales de grandes ciudades, 34 de los cuales realizaban PPB. El criterio más generalizado de indicación de ésta, fue la presencia de clínica atípica de asma (33/34) y el estímulo más utilizado, la inhalación de metacolina (33/34). Se detectó una gran uniformidad en los aspectos técnicos de preparación del fármaco, pero una gran heterogeneidad en cuanto a la forma de administrarlo y el protocolo seguido. Del mismo modo, se observó una gran diversidad en cuanto al valor de PC20/PD20 indicativo de hiperreactividad bronquial. Este trabajo nos aporta un mayor conocimiento de cuál es la realidad de las PPB inespecíficas en nuestro país, destacando la necesidad de conseguir una mayor homogeneidad en la metodología de realización, que nos permita valorar e interpretar los resultados de esta técnica diagnóstica con criterios más uniformes.</p></span>" ] "en" => array:1 [ "resumen" => "<span id="abst0010" class="elsevierStyleSection elsevierViewall"><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">With the aim of determining the current use of non-specific bronchial inhalation challenge (BIC) testing in Spain, 147 questionnaires were sent to hospitals with pneumology departments or units. The questionnaire covered general, technical and methodological aspects of this diagnostic procedure, as well as its assessment and interpretation. Of the 42 informants who returned questionnaires, mainly from large urban hospitals, 34 reported using BIC. The most widespread criterion applied in deciding to use BIC was the presence of atypical asthma symptoms (33/34). The stimulus most often used was methacholine inhalation (33/34). We found that technical preparation of the drug was highly standardized, but that administration and follow-up protocols differed greatly. There was also great variety in the PC20/PD20 value assigned to indícate bronchial hyperresponsiveness. This study contributes to our better understanding of the current use of BIC in Spain and highlights the need to work toward greater standardization for this diagnostic procedure, to enable us to assess and interpret the results more consistently.</p></span>" ] ] "bibliografia" => array:2 [ "titulo" => "Bibliografía" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:21 [ 0 => array:3 [ "identificador" => "bib0005" "etiqueta" => "1." 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O’Byrne" 5 => "S.D. Anderson" 6 => "E.F. Juniper" 7 => "J.L. Malo" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1183/09041950.053s1693" "Revista" => array:6 [ "tituloSerie" => "Eur Respir J" "fecha" => "1993" "volumen" => "6" "paginaInicial" => "53" "paginaFinal" => "83" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/24576917" "web" => "Medline" ] ] ] ] ] ] ] ] 12 => array:3 [ "identificador" => "bib0065" "etiqueta" => "13." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "A survey of the current use methods of analysis of bronchoprovocational challenges" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "G.C. Scott" 1 => "S.H. 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"referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Hiperreactividad bronquial concepto y consideraciones generales" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "M. Perpiñá Tordera" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "LibroEditado" => array:4 [ "titulo" => "Hiperreactividad bronquial inespecífica" "paginaInicial" => "1" "paginaFinal" => "14" "serieFecha" => "1993" ] ] ] ] ] ] 16 => array:3 [ "identificador" => "bib0085" "etiqueta" => "17." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Bronchial reactivity to inhaled histamine: a method and clinical survey" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "D.W. Cockcroft" 1 => "D.N. Killian" 2 => "J.J.A. Mellon" 3 => "F.E. Hargreave" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Clin Allergy" "fecha" => "1977" "volumen" => "7" "paginaInicial" => "235" "paginaFinal" => "243" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/908121" "web" => "Medline" ] ] ] ] ] ] ] ] 17 => array:3 [ "identificador" => "bib0090" "etiqueta" => "18." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Standardization of inhalation provocation tests: influence of nebulizer output, particle size, and method of inhalation" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:8 [ 0 => "G. Ryan" 1 => "M.B. Dolovich" 2 => "P. Eng" 3 => "G. Obminski" 4 => "D.W. Cockcroft" 5 => "E. Juniper" 6 => "F.E. Hargreave" 7 => "M.T. Newhouse" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "J Allergy Clin Immunol" "fecha" => "1981" "volumen" => "67" "paginaInicial" => "156" "paginaFinal" => "161" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/7451782" "web" => "Medline" ] ] ] ] ] ] ] ] 18 => array:3 [ "identificador" => "bib0095" "etiqueta" => "19." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The physical properties of a jet-nebulizer and their relevance for the histamine provocation test" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "P.J. Sterk" 1 => "A. Plomp" 2 => "M.J.J.S. Crobach" 3 => "J.F. Van de Vate" 4 => "PhH. 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| Year/Month | Html | Total | |
|---|---|---|---|
| 2024 November | 3 | 4 | 7 |
| 2024 October | 35 | 12 | 47 |
| 2024 September | 37 | 15 | 52 |
| 2024 August | 48 | 32 | 80 |
| 2024 July | 40 | 26 | 66 |
| 2024 June | 69 | 32 | 101 |
| 2024 May | 41 | 31 | 72 |
| 2024 April | 34 | 24 | 58 |
| 2024 March | 39 | 27 | 66 |
| 2024 February | 34 | 43 | 77 |
| 2024 January | 0 | 1 | 1 |
| 2023 December | 0 | 5 | 5 |
| 2023 November | 0 | 2 | 2 |
| 2023 October | 0 | 4 | 4 |
| 2023 September | 0 | 1 | 1 |
| 2023 August | 0 | 1 | 1 |
| 2023 July | 0 | 2 | 2 |
| 2023 June | 0 | 2 | 2 |
| 2023 March | 6 | 3 | 9 |
| 2023 February | 31 | 27 | 58 |
| 2023 January | 30 | 39 | 69 |
| 2022 December | 53 | 26 | 79 |
| 2022 November | 45 | 17 | 62 |
| 2022 October | 33 | 31 | 64 |
| 2022 September | 27 | 21 | 48 |
| 2022 August | 39 | 39 | 78 |
| 2022 July | 26 | 35 | 61 |
| 2022 June | 22 | 28 | 50 |
| 2022 May | 34 | 31 | 65 |
| 2022 April | 44 | 29 | 73 |
| 2022 March | 35 | 39 | 74 |
| 2022 February | 29 | 20 | 49 |
| 2022 January | 31 | 32 | 63 |
| 2021 December | 14 | 38 | 52 |
| 2021 November | 21 | 31 | 52 |
| 2021 October | 19 | 40 | 59 |
| 2021 September | 18 | 33 | 51 |
| 2021 August | 22 | 31 | 53 |
| 2021 July | 22 | 26 | 48 |
| 2021 June | 18 | 35 | 53 |
| 2021 May | 14 | 28 | 42 |
| 2021 April | 15 | 28 | 43 |
| 2021 March | 25 | 9 | 34 |
| 2021 February | 20 | 14 | 34 |
| 2021 January | 14 | 14 | 28 |
| 2020 December | 18 | 16 | 34 |
| 2020 November | 15 | 13 | 28 |
| 2020 October | 22 | 9 | 31 |
| 2020 September | 16 | 13 | 29 |
| 2020 August | 20 | 7 | 27 |
| 2020 July | 32 | 19 | 51 |
| 2020 June | 18 | 10 | 28 |
| 2020 May | 23 | 10 | 33 |
| 2020 April | 24 | 13 | 37 |
| 2020 March | 15 | 17 | 32 |
| 2020 February | 18 | 17 | 35 |
| 2020 January | 25 | 24 | 49 |
| 2019 December | 22 | 14 | 36 |
| 2019 November | 7 | 15 | 22 |
| 2019 October | 25 | 9 | 34 |
| 2019 September | 13 | 40 | 53 |
| 2019 August | 6 | 4 | 10 |
| 2019 July | 12 | 24 | 36 |
| 2019 June | 8 | 23 | 31 |
| 2019 May | 12 | 40 | 52 |
| 2019 April | 26 | 64 | 90 |
| 2019 March | 12 | 29 | 41 |
| 2019 February | 8 | 11 | 19 |
| 2019 January | 5 | 8 | 13 |
| 2018 December | 4 | 15 | 19 |
| 2018 November | 16 | 18 | 34 |
| 2018 October | 31 | 12 | 43 |
| 2018 September | 13 | 6 | 19 |
| 2018 May | 3 | 1 | 4 |
| 2018 April | 3 | 7 | 10 |
| 2018 March | 11 | 10 | 21 |
| 2018 February | 9 | 10 | 19 |
| 2018 January | 7 | 6 | 13 |
| 2017 December | 9 | 13 | 22 |
| 2017 November | 6 | 6 | 12 |
| 2017 October | 5 | 17 | 22 |
| 2017 September | 7 | 10 | 17 |
| 2017 August | 11 | 10 | 21 |
| 2017 July | 4 | 5 | 9 |
| 2017 June | 15 | 17 | 32 |
| 2017 May | 13 | 9 | 22 |
| 2017 April | 4 | 5 | 9 |
| 2017 March | 4 | 6 | 10 |
| 2017 February | 2 | 9 | 11 |
| 2017 January | 9 | 11 | 20 |
| 2016 December | 13 | 5 | 18 |
| 2016 November | 23 | 11 | 34 |
| 2016 October | 29 | 24 | 53 |
| 2016 September | 26 | 13 | 39 |
| 2016 August | 17 | 7 | 24 |
| 2016 July | 18 | 7 | 25 |
| 2016 June | 17 | 7 | 24 |
| 2016 May | 17 | 4 | 21 |
| 2016 April | 8 | 0 | 8 |
| 2016 March | 5 | 0 | 5 |
| 2016 February | 13 | 1 | 14 |
| 2016 January | 28 | 15 | 43 |
| 2015 December | 25 | 20 | 45 |
| 2015 November | 30 | 10 | 40 |
| 2015 October | 6 | 2 | 8 |
| 2015 September | 1 | 0 | 1 |
| 2015 June | 1 | 0 | 1 |
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