Mecanismos de acción de los glucocorticoides. Aplicación al tratamiento de la inflamación respiratoria
Read
158086
Timeswas read the article
155229
Total PDF
2857
Total HTML
Share statistics
array:23 [ "pii" => "S030028961530689X" "issn" => "03002896" "doi" => "10.1016/S0300-2896(15)30689-X" "estado" => "S300" "fechaPublicacion" => "1996-12-01" "aid" => "70759" "copyright" => "Sociedad Española de Neumología y Cirugía Torácica" "copyrightAnyo" => "1996" "documento" => "article" "crossmark" => 0 "subdocumento" => "fla" "cita" => "Arch Bronconeumol. 1996;32:527-34" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 44155 "formatos" => array:3 [ "EPUB" => 90 "HTML" => 964 "PDF" => 43101 ] ] "itemSiguiente" => array:18 [ "pii" => "S0300289615306906" "issn" => "03002896" "doi" => "10.1016/S0300-2896(15)30690-6" "estado" => "S300" "fechaPublicacion" => "1996-12-01" "aid" => "70760" "copyright" => "Sociedad Española de Neumología y Cirugía Torácica" "documento" => "article" "crossmark" => 0 "subdocumento" => "fla" "cita" => "Arch Bronconeumol. 1996;32:535-40" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 3164 "formatos" => array:3 [ "EPUB" => 96 "HTML" => 2001 "PDF" => 1067 ] ] "es" => array:10 [ "idiomaDefecto" => true "titulo" => "Libros publicados en España sobre tabaquismo" "tienePdf" => "es" "tieneTextoCompleto" => 0 "tieneResumen" => array:2 [ 0 => "es" 1 => "en" ] "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "535" "paginaFinal" => "540" ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "The publication of books on tobacco dependence in Spain" ] ] "contieneResumen" => array:2 [ "es" => true "en" => true ] "contienePdf" => array:1 [ "es" => true ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "E. Guardiola, J. Sánchez-Carbonell" "autores" => array:2 [ 0 => array:2 [ "nombre" => "E." "apellidos" => "Guardiola" ] 1 => array:2 [ "nombre" => "J." "apellidos" => "Sánchez-Carbonell" ] ] ] ] ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0300289615306906?idApp=UINPBA00003Z" "url" => "/03002896/0000003200000010/v1_201506230103/S0300289615306906/v1_201506230103/es/main.assets" ] "itemAnterior" => array:18 [ "pii" => "S0300289615306888" "issn" => "03002896" "doi" => "10.1016/S0300-2896(15)30688-8" "estado" => "S300" "fechaPublicacion" => "1996-12-01" "aid" => "70758" "copyright" => "Sociedad Española de Neumología y Cirugía Torácica" "documento" => "article" "crossmark" => 0 "subdocumento" => "fla" "cita" => "Arch Bronconeumol. 1996;32:523-6" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 1495 "formatos" => array:3 [ "EPUB" => 69 "HTML" => 686 "PDF" => 740 ] ] "es" => array:10 [ "idiomaDefecto" => true "titulo" => "Estudio comparativo de los niveles de receptor soluble de interleucina 2 y adenosín-desaminasa en líquidos pleurales tuberculosos y de otras etiologías" "tienePdf" => "es" "tieneTextoCompleto" => 0 "tieneResumen" => array:2 [ 0 => "es" 1 => "en" ] "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "523" "paginaFinal" => "526" ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Comparative assessment of soluble interleukin 2 receptor and adenosin-desaminase levels in pleural fluid of patients with tubercsulosis or other diseases" ] ] "contieneResumen" => array:2 [ "es" => true "en" => true ] "contienePdf" => array:1 [ "es" => true ] "autores" => array:2 [ 0 => array:2 [ "autoresLista" => "M.J. Avilés Inglés, C. Contessotto" "autores" => array:2 [ 0 => array:2 [ "nombre" => "M.J." "apellidos" => "Avilés Inglés" ] 1 => array:2 [ "nombre" => "C." "apellidos" => "Contessotto" ] ] ] 1 => array:2 [ "autoresLista" => "J. Ontañón, M. Muro, P. Berlinches, J. de la Torre, F. Sánchez Gascón, M.R. Álvarez López" "autores" => array:6 [ 0 => array:2 [ "nombre" => "J." "apellidos" => "Ontañón" ] 1 => array:2 [ "nombre" => "M." "apellidos" => "Muro" ] 2 => array:2 [ "nombre" => "P." "apellidos" => "Berlinches" ] 3 => array:2 [ "nombre" => "J." "apellidos" => "de la Torre" ] 4 => array:2 [ "nombre" => "F." "apellidos" => "Sánchez Gascón" ] 5 => array:2 [ "nombre" => "M.R." "apellidos" => "Álvarez López" ] ] ] ] ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0300289615306888?idApp=UINPBA00003Z" "url" => "/03002896/0000003200000010/v1_201506230103/S0300289615306888/v1_201506230103/es/main.assets" ] "es" => array:10 [ "idiomaDefecto" => true "titulo" => "Mecanismos de acción de los glucocorticoides. Aplicación al tratamiento de la inflamación respiratoria" "tieneTextoCompleto" => 0 "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "527" "paginaFinal" => "534" ] ] "autores" => array:1 [ 0 => array:4 [ "autoresLista" => "J. Mullol, L. Pujols, C. Picado" "autores" => array:3 [ 0 => array:3 [ "nombre" => "J." "apellidos" => "Mullol" "referencia" => array:3 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">*</span>" "identificador" => "aff0005" ] 1 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">**</span>" "identificador" => "aff0010" ] 2 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">1</span>" "identificador" => "cor0005" ] ] ] 1 => array:3 [ "nombre" => "L." "apellidos" => "Pujols" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">**</span>" "identificador" => "aff0010" ] ] ] 2 => array:3 [ "nombre" => "C." "apellidos" => "Picado" "referencia" => array:2 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">*</span>" "identificador" => "aff0005" ] 1 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">**</span>" "identificador" => "aff0010" ] ] ] ] "afiliaciones" => array:2 [ 0 => array:3 [ "entidad" => "Servicio de Neumología. Departament de Medicina. Universitat de Barcelona. Barcelona" "etiqueta" => "*" "identificador" => "aff0005" ] 1 => array:3 [ "entidad" => "Servicio de Alergia Respiratoria. Fundació Clínic per a la Recerca Biomédica. Hospital Clínic i Universitari. Departament de Medicina. Universitat de Barcelona" "etiqueta" => "**" "identificador" => "aff0010" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "1" "correspondencia" => "Correspondencia: Servicio de Neumología y Alergia Respiratoria. Hospital Clínic i Universitari. Villarroel, 170. 08036 Barcelona." ] ] ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "1996-04-23" "fechaAceptado" => "1996-04-30" "bibliografia" => array:2 [ "titulo" => "Bibliografía" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:83 [ 0 => array:3 [ "identificador" => "bib0005" "etiqueta" => "1." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "On the constitutional and local effects of disease of the suprarenal capsules" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "T. Addison" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Libro" => array:3 [ "fecha" => "1855" "editorial" => "Samuel Highley" "editorialLocalizacion" => "Londres" ] ] ] ] ] ] 1 => array:3 [ "identificador" => "bib0010" "etiqueta" => "2." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Glucocorticosteroids. Their mechanisms of action and use in allergic diseases." "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "R.P. Schleimer" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "LibroEditado" => array:4 [ "titulo" => "Allergy. Principies and Practice" "paginaInicial" => "893" "paginaFinal" => "925" "serieFecha" => "1993" ] ] ] ] ] ] 2 => array:3 [ "identificador" => "bib0015" "etiqueta" => "3." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The basophil adenomas of the pituitary body and their clinical manifestations" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "H. Cushing" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Bull Johns Hopkins Hosp" "fecha" => "1932" "volumen" => "50" "paginaInicial" => "137" "paginaFinal" => "195" ] ] ] ] ] ] 3 => array:3 [ "identificador" => "bib0020" "etiqueta" => "4." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Chemistry of corticotrophin" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "E.B. Astwood" 1 => "M.S. Raben" 2 => "R.W. Payne" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Recent Prog Horm Res" "fecha" => "1952" "volumen" => "7" "paginaInicial" => "1" "paginaFinal" => "57" ] ] ] ] ] ] 4 => array:3 [ "identificador" => "bib0025" "etiqueta" => "5." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Neural control of the pituitary gland" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "G.W. Harris" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Physiol Rev" "fecha" => "1948" "volumen" => "28" "paginaInicial" => "139" "paginaFinal" => "179" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/18865220" "web" => "Medline" ] ] ] ] ] ] ] ] 5 => array:3 [ "identificador" => "bib0030" "etiqueta" => "6." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Characterization of a 41-residue ovine hypothalamic peptide that stimulates secretion of corticotropin and β-endorphin" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "W. Vale" 1 => "J. Spiess" 2 => "C. Rivier" 3 => "J. Rivier" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Science" "fecha" => "1981" "volumen" => "213" "paginaInicial" => "1.394" "paginaFinal" => "1.397" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/7268441" "web" => "Medline" ] ] ] ] ] ] ] ] 6 => array:3 [ "identificador" => "bib0035" "etiqueta" => "7." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The effect of a hormone of the adrenal cortex (17-hydroxy-l1-dehydrocorticosterone; compound E) and of pituitary adrenocorticotropic hormone on rheumatoid arthritis" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "P.S. Hensch" 1 => "E.C. Kendall" 2 => "C.H. Slocumb" 3 => "H.F. Polley" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Proc Staff Meet Mayo Clinic" "fecha" => "1949" "volumen" => "24" "paginaInicial" => "181" "paginaFinal" => "197" ] ] ] ] ] ] 7 => array:3 [ "identificador" => "bib0040" "etiqueta" => "8." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Adrenocorticotropic hormone: adrenocortical steroids and their synthetic analogs; inhibitor of the synthesis and actions of adrenocortical hormones" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "P. Schimmer" 1 => "K.L. Parker" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "LibroEditado" => array:4 [ "titulo" => "Goodman & Gilman's the pharmacological basis of therapeutics" "paginaInicial" => "1.459" "paginaFinal" => "1.485" "serieFecha" => "1996" ] ] ] ] ] ] 8 => array:3 [ "identificador" => "bib0045" "etiqueta" => "9." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Daily cortisol production rate in man determined by stable isotope dilution/mass spectrometry" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "N.V. Esteban" 1 => "T. Loughlin" 2 => "A.L. Yergey" 3 => "J.K. Zawadzki" 4 => "J.D. Booth" 5 => "J.C. Winterer" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1210/jcem-72-1-39" "Revista" => array:6 [ "tituloSerie" => "J Clin Endocrinol Metab" "fecha" => "1991" "volumen" => "72" "paginaInicial" => "39" "paginaFinal" => "45" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/1986026" "web" => "Medline" ] ] ] ] ] ] ] ] 9 => array:3 [ "identificador" => "bib0050" "etiqueta" => "10." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Efficacy and safety of inhaled corticosteroids in asthma" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "P.J. Barnes" 1 => "S. Pedersen" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Am Rev Respir Dis" "fecha" => "1993" "volumen" => "148" "paginaInicial" => "1" "paginaFinal" => "26" ] ] ] ] ] ] 10 => array:3 [ "identificador" => "bib0055" "etiqueta" => "11." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Fluticasone propionate: an update on preclinical and clinical experience" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "R. Fuller" 1 => "M. Johnson" 2 => "A. Bye" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Resp Med" "fecha" => "1995" "volumen" => "89" "numero" => "Supl A" "paginaInicial" => "3" "paginaFinal" => "18" ] ] ] ] ] ] 11 => array:3 [ "identificador" => "bib0060" "etiqueta" => "12." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Two signáis mediate hormone-dependent nuclear localization of the glucocorticoid receptor" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "D. Picard" 1 => "K.R. Yamamoto" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "EMBO J" "fecha" => "1987" "volumen" => "6" "paginaInicial" => "3.333" "paginaFinal" => "3.340" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16453815" "web" => "Medline" ] ] ] ] ] ] ] ] 12 => array:3 [ "identificador" => "bib0065" "etiqueta" => "13." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Intracellular localisation of the glucocorticoid receptor: evidence for cytoplasmic and nuclear localisation" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "A.C. Wikstrom" 1 => "O. Bakke" 2 => "S. Okret" 3 => "M. Brönnegärd" 4 => "J.A. Gustafsson" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1210/endo-120-6-2529" "Revista" => array:6 [ "tituloSerie" => "Endocrinology" "fecha" => "1987" "volumen" => "120" "paginaInicial" => "1.232" "paginaFinal" => "1.242" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/3569142" "web" => "Medline" ] ] ] ] ] ] ] ] 13 => array:3 [ "identificador" => "bib0070" "etiqueta" => "14." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The steroid and thyroid hormone receptor superfamily" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "R.M. Evans" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Science" "fecha" => "1988" "volumen" => "247" "paginaInicial" => "889" "paginaFinal" => "895" ] ] ] ] ] ] 14 => array:3 [ "identificador" => "bib0075" "etiqueta" => "15." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Primary structure and expression of a functional human glucocorticoid receptor cDNA" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "S.M. Hollenberg" 1 => "C. Weinberger" 2 => "E.S. Ong" 3 => "G. Cerelli" 4 => "A. Oro" 5 => "R. Lebo" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Nature" "fecha" => "1985" "volumen" => "318" "paginaInicial" => "635" "paginaFinal" => "641" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/2867473" "web" => "Medline" ] ] ] ] ] ] ] ] 15 => array:3 [ "identificador" => "bib0080" "etiqueta" => "16." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The genomic structure of the human glucocorticoid receptor" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "I.J. Encío" 1 => "S.D. Detera-Wadleigh" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "J Biol Chem" "fecha" => "1991" "volumen" => "266" "paginaInicial" => "7.182" "paginaFinal" => "7.188" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/1840597" "web" => "Medline" ] ] ] ] ] ] ] ] 16 => array:3 [ "identificador" => "bib0085" "etiqueta" => "17." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Functional domains of the human glucocorticoid receptor" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "V. Ciguère" 1 => "S.M. Hollenberg" 2 => "M.G. Rosenfield" 3 => "R.M. Evans" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Cell" "fecha" => "1986" "volumen" => "46" "paginaInicial" => "645" "paginaFinal" => "652" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/3742595" "web" => "Medline" ] ] ] ] ] ] ] ] 17 => array:3 [ "identificador" => "bib0090" "etiqueta" => "18." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Múltiple and cooperative trans-activation domains of the human glucocorticoid receptor" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "S.M. Hollenberg" 1 => "R.M. Evans" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Cell" "fecha" => "1988" "volumen" => "55" "paginaInicial" => "899" "paginaFinal" => "906" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/3191531" "web" => "Medline" ] ] ] ] ] ] ] ] 18 => array:3 [ "identificador" => "bib0095" "etiqueta" => "19." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Delineation of a small región within the major transactivation domain of the human glucocorticoid receptor that mediates transactivation of gene expression" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "K. Dahlman-Wright" 1 => "T. Almlof" 2 => "I.J. McEwan" 3 => "J.A. Gustafsson" 4 => "A.P.H. Wright" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Proc Natl Acad Sci USA" "fecha" => "1994" "volumen" => "91" "paginaInicial" => "1.619" "paginaFinal" => "1.623" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11607502" "web" => "Medline" ] ] ] ] ] ] ] ] 19 => array:3 [ "identificador" => "bib0100" "etiqueta" => "20." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Protein components of the nonactivated glucocorticoids receptor" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "M. Rexin" 1 => "W. Busch" 2 => "U. Gehring" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "J Biol Chem" "fecha" => "1991" "volumen" => "266" "paginaInicial" => "24.601" "paginaFinal" => "24.605" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/1761564" "web" => "Medline" ] ] ] ] ] ] ] ] 20 => array:3 [ "identificador" => "bib0105" "etiqueta" => "21." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Regulation of glucocorticoid receptors by glucocorticoids in cultured HeLa S, cells" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "J.A. Cidlowski" 1 => "N.B. Cidlowski" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1210/endo-109-6-2264" "Revista" => array:7 [ "tituloSerie" => "Endocrinology" "fecha" => "1981" "volumen" => "109" "paginaInicial" => "1.975" "paginaFinal" => "1.981" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/7308153" "web" => "Medline" ] ] "itemHostRev" => array:3 [ "pii" => "S0210569109001739" "estado" => "S300" "issn" => "02105691" ] ] ] ] ] ] ] 21 => array:3 [ "identificador" => "bib0110" "etiqueta" => "22." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Mechanism of glucocorticoid receptor down-regulation by glucocorticoids" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "S. Rosewicz" 1 => "A.R. McDonald" 2 => "B.A. Maddux" 3 => "I.D. Goldfine" 4 => "R.L. Miesfield" 5 => "C.D. Logsdon" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "J Biol Chem" "fecha" => "1988" "volumen" => "263" "paginaInicial" => "2.581" "paginaFinal" => "2.584" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/3198651" "web" => "Medline" ] ] ] ] ] ] ] ] 22 => array:3 [ "identificador" => "bib0115" "etiqueta" => "23." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Intragenic sequences of the human glucocorticoid receptor complementary DNA mediate hormone-inducible receptor messenger RNA downregulation through multiple mechanisms" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "K.L. Burnstein" 1 => "C.M. Jewell" 2 => "M. Sar" 3 => "J.A. Cidlowski" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1210/mend.8.12.7708066" "Revista" => array:7 [ "tituloSerie" => "Mol Endocrinol" "fecha" => "1994" "volumen" => "8" "paginaInicial" => "1.764" "paginaFinal" => "1.773" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/7708066" "web" => "Medline" ] ] "itemHostRev" => array:3 [ "pii" => "S0210569111003457" "estado" => "S300" "issn" => "02105691" ] ] ] ] ] ] ] 23 => array:3 [ "identificador" => "bib0120" "etiqueta" => "24." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Genes newly identified as regulated by glucocorticoids in murine thymocytes" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "G. Baughman" 1 => "M.T. Harrigan" 2 => "N.F. Campbell" 3 => "S.J. Nurrish" 4 => "S. Bourgeois" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1210/mend-5-5-637" "Revista" => array:6 [ "tituloSerie" => "Mol Endocrinol" "fecha" => "1991" "volumen" => "5" "paginaInicial" => "637" "paginaFinal" => "644" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/2072923" "web" => "Medline" ] ] ] ] ] ] ] ] 24 => array:3 [ "identificador" => "bib0125" "etiqueta" => "25." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Transcription factor interactions: selectors of positive or negative regulation from a single DNA element" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "M.I. Diamond" 1 => "J.N. Miner" 2 => "S.K. Yoshinaga" 3 => "K.R. Yamamoto" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Science" "fecha" => "1990" "volumen" => "249" "paginaInicial" => "1.266" "paginaFinal" => "1.272" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/2218499" "web" => "Medline" ] ] ] ] ] ] ] ] 25 => array:3 [ "identificador" => "bib0130" "etiqueta" => "26." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Glucocorticoid resistance in asthma" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "P.J. Barnes" 1 => "A.P. Greening" 2 => "G.K. Crompton" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1164/ajrccm.152.6.8520795" "Revista" => array:6 [ "tituloSerie" => "Am J Respir Crit Care Med" "fecha" => "1995" "volumen" => "152" "paginaInicial" => "5.125" "paginaFinal" => "5.142" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8520795" "web" => "Medline" ] ] ] ] ] ] ] ] 26 => array:3 [ "identificador" => "bib0135" "etiqueta" => "27." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The inducible transcription factor NF-kB: structure-function relationship of its protein subunits" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "S.M. Grimm" 1 => "P.A. Baeurle" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Biochem J" "fecha" => "1993" "volumen" => "290" "paginaInicial" => "297" "paginaFinal" => "308" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8452515" "web" => "Medline" ] ] ] ] ] ] ] ] 27 => array:3 [ "identificador" => "bib0140" "etiqueta" => "28." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Cytokine signal transduction" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "T. Kishimoto" 1 => "R. Taga" 2 => "S. Akira" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Cell" "fecha" => "1994" "volumen" => "76" "paginaInicial" => "253" "paginaFinal" => "262" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8293462" "web" => "Medline" ] ] ] ] ] ] ] ] 28 => array:3 [ "identificador" => "bib0145" "etiqueta" => "29." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Effects of dexamethasone on cytokine and phorbol ester stimulated c-Fos and c-Jun DNA binding and gene expression in human lung" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "I.M. Adcock" 1 => "C.R. Brown" 2 => "H. Shirasaki" 3 => "P.J. Barnes" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Eur Respir J" "fecha" => "1994" "volumen" => "7" "paginaInicial" => "2.117" "paginaFinal" => "2.123" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/7713210" "web" => "Medline" ] ] ] ] ] ] ] ] 29 => array:3 [ "identificador" => "bib0150" "etiqueta" => "30." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Effects of glucocorticoids on transcription factor activation in human peripheral blood mononuclear cells" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "I.M. Adcock" 1 => "C.R. Brown" 2 => "C.M. Gelder" 3 => "H. Shirasaki" 4 => "M.J. Peters" 5 => "P.J. Barnes" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Am J Physiol" "fecha" => "1995" "volumen" => "268" "paginaInicial" => "C331" "paginaFinal" => "C338" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/7864072" "web" => "Medline" ] ] ] ] ] ] ] ] 30 => array:3 [ "identificador" => "bib0155" "etiqueta" => "31." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Actions of the glucocorticoid receptor on transcription factors within the cytoplasma" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "I.M. Adcock" 1 => "P.J. Barnes" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:4 [ "tituloSerie" => "Am J Respir Crit Care Med" "fecha" => "1995" "volumen" => "151" "paginaInicial" => "A195" ] ] ] ] ] ] 31 => array:3 [ "identificador" => "bib0160" "etiqueta" => "32." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Characterization of mechanisms involved in transrepression of NF-kB by activated glucocorticoid receptors" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "R.I. Scheinman" 1 => "A. Gualberto" 2 => "C.M. Jewell" 3 => "J.A. Cidlowski" 4 => "A.S. Baldwin Jr." ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Mol Cell Biol" "fecha" => "1995" "volumen" => "15" "paginaInicial" => "943" "paginaFinal" => "953" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/7823959" "web" => "Medline" ] ] ] ] ] ] ] ] 32 => array:3 [ "identificador" => "bib0165" "etiqueta" => "33." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Glucocorticoid receptor-cAMP response element-binding protein interaction and the response of the phosphoenolpyruvate carboxykinase gene to glucocorticoids" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "F. Imai" 1 => "J.N. Minger" 2 => "J.A. Mitchell" 3 => "K.R. Yamamoto" 4 => "D.K. Granner" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "J Biol Chem" "fecha" => "1993" "volumen" => "268" "paginaInicial" => "5.353" "paginaFinal" => "5.356" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8262987" "web" => "Medline" ] ] ] ] ] ] ] ] 33 => array:3 [ "identificador" => "bib0170" "etiqueta" => "34." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Beta-adrenoceptor agonists interfere with glucocorticoid receptor DNA-binding in rat lung" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "M.J. Peters" 1 => "I.M. Adcock" 2 => "C.R. Brown" 3 => "P.J. Barnes" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Eur J Pharmacol (Mol Pharm)" "fecha" => "1995" "volumen" => "289" "paginaInicial" => "275" "paginaFinal" => "281" ] ] ] ] ] ] 34 => array:3 [ "identificador" => "bib0175" "etiqueta" => "35." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Glucocorticoid effects on the production and action of immune cytokines" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "P.M. Guyre" 1 => "M.T. Girard" 2 => "P.M. Morganelli" 3 => "P.D. Manginiello" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "J Steroid Biochem" "fecha" => "1988" "volumen" => "30" "paginaInicial" => "89" "paginaFinal" => "93" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/2968487" "web" => "Medline" ] ] ] ] ] ] ] ] 35 => array:3 [ "identificador" => "bib0180" "etiqueta" => "36." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Dexamethaso-ne inhibition of interleukin-l-beta production by human monocytes" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "J.A. Kem" 1 => "R.J. Lamb" 2 => "J.L. Reed" 3 => "R.P. Daniele" 4 => "P.L. Nowell" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Post-transcriptional mechanisms. J Clin Invest" "fecha" => "1988" "volumen" => "81" "paginaInicial" => "237" "paginaFinal" => "244" ] ] ] ] ] ] 36 => array:3 [ "identificador" => "bib0185" "etiqueta" => "37." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Expression of interleukin-2, interferon-γ, and the IL-2 receptor by human peripheral blood lymphocytes" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "K. Grabstein" 1 => "S. Dower" 2 => "S. Gillis" 3 => "V. Urdal" 4 => "A. Larsen" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "J Immunol" "fecha" => "1986" "volumen" => "136" "paginaInicial" => "4.503" "paginaFinal" => "4.508" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/3711662" "web" => "Medline" ] ] ] ] ] ] ] ] 37 => array:3 [ "identificador" => "bib0190" "etiqueta" => "38." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Glucocorticoids inhibit the expression of an inducible, but not the constitutive nitric oxide synthase in vascular endothelial cells" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "M.W. Radomski" 1 => "R.M.J. Palmer" 2 => "S. Moneada" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Proc Natl Acad Sci USA" "fecha" => "1990" "volumen" => "87" "paginaInicial" => "10.043" "paginaFinal" => "10.049" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/2263643" "web" => "Medline" ] ] ] ] ] ] ] ] 38 => array:3 [ "identificador" => "bib0195" "etiqueta" => "39." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Glucocorticoid-andnon-glucocorticoid induction of lipocortins (annexins) 1 and 2 in rat peritoneal leucocytes in vivo" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "S.H. Peers" 1 => "F. Smillie" 2 => "A.J. Elderfield" 3 => "R.J. Flower" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Br J Pharmacol" "fecha" => "1993" "volumen" => "108" "paginaInicial" => "66" "paginaFinal" => "72" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8428216" "web" => "Medline" ] ] ] ] ] ] ] ] 39 => array:3 [ "identificador" => "bib0200" "etiqueta" => "40." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Cytokineand forskolin-induced synthesis of group II phospholipase A2 and prostaglandin E, in rat mesangial cells is prevented hy dexamethasone" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "C. Schalkwijk" 1 => "M. Vervoordeldonk" 2 => "J. Pfeilschifter" 3 => "F. Marki" 4 => "H. Vanden Bosch" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Biochem Biophys Res Commun" "fecha" => "1991" "volumen" => "180" "paginaInicial" => "46" "paginaFinal" => "52" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/1930239" "web" => "Medline" ] ] ] ] ] ] ] ] 40 => array:3 [ "identificador" => "bib0205" "etiqueta" => "41." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "cDNA cloning and functional activity of a glucocorticoid-regulated inflammatory cyclooxygenase" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "M.K. O’Banion" 1 => "V.D. Winn" 2 => "D.A. Young" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Proc Natl Acad Sci USA" "fecha" => "1992" "volumen" => "89" "paginaInicial" => "4.888" "paginaFinal" => "4.892" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/1465455" "web" => "Medline" ] ] ] ] ] ] ] ] 41 => array:3 [ "identificador" => "bib0210" "etiqueta" => "42." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Glucocorticoids induce neutral endopeptidase in transformed human tracheal epithelial cells" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "D.B. Borson" 1 => "S. Jew" 2 => "D.C. Gruenert" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Am J Physiol" "fecha" => "1991" "volumen" => "260" "paginaInicial" => "L83" "paginaFinal" => "L89" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/1847594" "web" => "Medline" ] ] ] ] ] ] ] ] 42 => array:3 [ "identificador" => "bib0215" "etiqueta" => "43." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Leukotriene B4 stimulates c-fos and c-jun gene transcription and AP-1 binding activity in human monocytes" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "J. Stankova" 1 => "M. Rola-Pleszczynski" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Biochem J" "fecha" => "1992" "volumen" => "282" "paginaInicial" => "625" "paginaFinal" => "629" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/1313226" "web" => "Medline" ] ] ] ] ] ] ] ] 43 => array:3 [ "identificador" => "bib0220" "etiqueta" => "44." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Glucocorticosteroids increase beta 2-adrenergic receptor transcription in human lung" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "J.C. Mak" 1 => "M. Nishikawa" 2 => "P.J. Barnes" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Am J Physiol" "fecha" => "1995" "volumen" => "268" "paginaInicial" => "L41" "paginaFinal" => "L46" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/7840227" "web" => "Medline" ] ] ] ] ] ] ] ] 44 => array:3 [ "identificador" => "bib0225" "etiqueta" => "45." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Increased tachykinin receptor gene expression in asthmatic lung and its modulation by steroids" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "I.M. Adcock" 1 => "M. Peters" 2 => "C. Gelder" 3 => "H. Shirasaki" 4 => "C.R. Brown" 5 => "P.J. Barnes" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "J Mol Endocrinol" "fecha" => "1993" "volumen" => "11" "paginaInicial" => "1" "paginaFinal" => "7" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8240667" "web" => "Medline" ] ] ] ] ] ] ] ] 45 => array:3 [ "identificador" => "bib0230" "etiqueta" => "46." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "A mechanism for the antiinflammatory effects of corticosteroids: the glucocorticoid receptor regulates leukocyte adhesion to endothelial cells and expression of endothelial-leukocyte adhesion molecule-1 and intercellular adhesion molecule-1" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "B.N. Cronstein" 1 => "S.C. Kimmel" 2 => "R.I. Levin" 3 => "F. Martiniuk" 4 => "G. Weissmann" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:7 [ "tituloSerie" => "Proc Natl Acad Sci USA" "fecha" => "1992" "volumen" => "89" "paginaInicial" => "9.991" "paginaFinal" => "9.995" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/1465455" "web" => "Medline" ] ] "itemHostRev" => array:3 [ "pii" => "S0210569111000763" "estado" => "S300" "issn" => "02105691" ] ] ] ] ] ] ] 46 => array:3 [ "identificador" => "bib0235" "etiqueta" => "47." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Comparison of the role of nasal polyp and normal nasal mucosal epithelial cells on in vitro eosinophil survival. Mediation by GM-CSF and inhibition of dexamethasone" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "A. Xaubet" 1 => "J. Mullol" 2 => "E. López" 3 => "J. Roca-Ferrer" 4 => "M. Rozman" 5 => "M. Carrión" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Clin Exp Allergy" "fecha" => "1994" "volumen" => "24" "paginaInicial" => "307" "paginaFinal" => "317" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8039016" "web" => "Medline" ] ] ] ] ] ] ] ] 47 => array:3 [ "identificador" => "bib0240" "etiqueta" => "48." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Effects of topical steroids on cytokine release from human nasal epithelial cells in vitro" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "A. Xaubet" 1 => "J. Mullol" 2 => "J. Roca-Ferrer" 3 => "E. López" 4 => "J.C. Fernández" 5 => "C. Picado" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:4 [ "tituloSerie" => "Am J Respir Crit Care Med" "fecha" => "1995" "volumen" => "151" "paginaInicial" => "A367" ] ] ] ] ] ] 48 => array:3 [ "identificador" => "bib0245" "etiqueta" => "49." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Identification of mRNAs associated with programmed cell death in immature thymocytes" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "G.P. Owens" 1 => "W.E. Hahn" 2 => "J.J. Cohen" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Mol Cell Biol" "fecha" => "1991" "volumen" => "11" "paginaInicial" => "4.177" "paginaFinal" => "4.188" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/1944288" "web" => "Medline" ] ] ] ] ] ] ] ] 49 => array:3 [ "identificador" => "bib0250" "etiqueta" => "50." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Glucocorticoids inhibit cytokine-mediated eosinophil survival" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "N. Wallen" 1 => "H. Kita" 2 => "D. Weiler" 3 => "G.J. Gleich" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "J Immunol" "fecha" => "1991" "volumen" => "147" "paginaInicial" => "3.490" "paginaFinal" => "3.495" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/1836480" "web" => "Medline" ] ] ] ] ] ] ] ] 50 => array:3 [ "identificador" => "bib0255" "etiqueta" => "51." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Vasocort: a novel glucocorticoid-induced anti-inflammatory protein" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "R. Carnuccio" 1 => "M. Di Rosa" 2 => "B. Guerrasio" 3 => "T. Iuvone" 4 => "L. Satebin" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Br J. Pharmacol" "fecha" => "1987" "volumen" => "90" "paginaInicial" => "443" "paginaFinal" => "445" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/2952212" "web" => "Medline" ] ] ] ] ] ] ] ] 51 => array:3 [ "identificador" => "bib0420" "etiqueta" => "52." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Dexamethasone inhibits respiratory glycoconjugate secretion from feline airways in vitro by the induction of lipocortin (lipomodulin) synthesis" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "J.D. Lundgren" 1 => "F. Hirata" 2 => "Z. Marom" 3 => "C. Logun" 4 => "L. Steel" 5 => "M. Kaliner" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1164/ajrccm/137.2.353" "Revista" => array:6 [ "tituloSerie" => "Am Rev Respir Dis" "fecha" => "1988" "volumen" => "137" "paginaInicial" => "353" "paginaFinal" => "357" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/2963568" "web" => "Medline" ] ] ] ] ] ] ] ] 52 => array:3 [ "identificador" => "bib0265" "etiqueta" => "53." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Direct inhibitory action of glucocorticoids on glycoconjugate secretion from airway submucosal glands" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "S. Shimura" 1 => "T. Sasaki" 2 => "K. Ikeda" 3 => "K. Yamauchi" 4 => "H. Sasaki" 5 => "T. Takishima" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1164/ajrccm/141.6.1569" "Revista" => array:6 [ "tituloSerie" => "Am Rev Respir Dis" "fecha" => "1990" "volumen" => "141" "paginaInicial" => "1.044" "paginaFinal" => "1.049" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/2350100" "web" => "Medline" ] ] ] ] ] ] ] ] 53 => array:3 [ "identificador" => "bib0270" "etiqueta" => "54." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Molecular physiology of the regulation of hepatic gluconeogenesis and glycolysis" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "S.J. Pilkis" 1 => "D.K. Granner" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1146/annurev.ph.54.030192.004321" "Revista" => array:6 [ "tituloSerie" => "Annu Rev Physiol" "fecha" => "1992" "volumen" => "54" "paginaInicial" => "885" "paginaFinal" => "909" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/1562196" "web" => "Medline" ] ] ] ] ] ] ] ] 54 => array:3 [ "identificador" => "bib0275" "etiqueta" => "55." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The hypothalamic-pituitary-adrenal axis and immune-mediated inflammation" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "G.P. Chrousos" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1056/NEJM199506293322611" "Revista" => array:6 [ "tituloSerie" => "N Engl J Med" "fecha" => "1995" "volumen" => "332" "paginaInicial" => "1.351" "paginaFinal" => "1.362" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/7760898" "web" => "Medline" ] ] ] ] ] ] ] ] 55 => array:3 [ "identificador" => "bib0280" "etiqueta" => "56." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Effect of systemic and inhaled glucocorticoid on eosinophil survival induced by epithelial cells from inflammatory and non-inflammatory respiratory mucosa" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "J. Mullol" 1 => "A. Xaubet" 2 => "E. López" 3 => "J. Roca-Ferrer" 4 => "J.M. Fabra" 5 => "C. Picado" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Thorax" "fecha" => "1995" "volumen" => "50" "paginaInicial" => "270" "paginaFinal" => "274" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/7660341" "web" => "Medline" ] ] ] ] ] ] ] ] 56 => array:3 [ "identificador" => "bib0285" "etiqueta" => "57." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Corticosteroid-induced osteoporosis" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "J.D. Adachi" 1 => "W.G. Bensen" 2 => "A.B. Hodsman" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Semin Arthritis Rheum" "fecha" => "1993" "volumen" => "22" "paginaInicial" => "375" "paginaFinal" => "384" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8342044" "web" => "Medline" ] ] ] ] ] ] ] ] 57 => array:3 [ "identificador" => "bib0290" "etiqueta" => "58." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Neurosteroids: biochemistry, modes of action, and clinical relevance" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "S.H. Mellon" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1210/jcem.78.6.7515391" "Revista" => array:4 [ "tituloSerie" => "J Clin Endocrinol Metab" "fecha" => "1994" "volumen" => "78" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/7515391" "web" => "Medline" ] ] ] ] ] ] ] ] 58 => array:3 [ "identificador" => "bib0295" "etiqueta" => "59." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Steroid resistance in bronchial asthma" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "H.J. Schwartz" 1 => "F.C. Lowell" 2 => "J.C. Melby" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Am J Int Med" "fecha" => "1968" "volumen" => "69" "paginaInicial" => "493" "paginaFinal" => "499" ] ] ] ] ] ] 59 => array:3 [ "identificador" => "bib0300" "etiqueta" => "60." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Familial and iatrogenic cortisol receptor resistance" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "S.W. Lamberts" 1 => "J.W. Koper" 2 => "F.H. De Jong" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "J Steroid Biochem Mol Biol" "fecha" => "1992" "volumen" => "43" "paginaInicial" => "385" "paginaFinal" => "388" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/1390287" "web" => "Medline" ] ] ] ] ] ] ] ] 60 => array:3 [ "identificador" => "bib0305" "etiqueta" => "61." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Glucocorticoid therapy for asthma: clinical pharmacology" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "S. Szefler" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "J Allergy Clin Immunol" "fecha" => "1991" "volumen" => "88" "paginaInicial" => "147" "paginaFinal" => "165" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/1880315" "web" => "Medline" ] ] ] ] ] ] ] ] 61 => array:3 [ "identificador" => "bib0310" "etiqueta" => "62." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Glucocorticoid resistance in chronic asthma. Glucocorticoid pharmacokinetics, glucocorticoid receptor characteristics, and inhibition of peripheral blood T cell proliferation by glucocorticoids in vitro" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "C.J. Corrigan" 1 => "P.H. Brown" 2 => "N.C. Barnes" 3 => "S.J. Szefler" 4 => "J.J. Tsai" 5 => "A.J. Frew" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1164/ajrccm/144.6.1342" "Revista" => array:6 [ "tituloSerie" => "Am Rev Respir Dis" "fecha" => "1991" "volumen" => "144" "paginaInicial" => "1.016" "paginaFinal" => "1.025" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/1835825" "web" => "Medline" ] ] ] ] ] ] ] ] 62 => array:3 [ "identificador" => "bib0315" "etiqueta" => "63." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Steroid-resistant asthma: immunologic and pharmacologic features" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "J. Álvarez" 1 => "W. Surs" 2 => "D.Y. Leung" 3 => "D. Ikle" 4 => "E.W. Gelfand" 5 => "S.J. Szefler" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "J Allergy Clin Immunol" "fecha" => "1992" "volumen" => "89" "paginaInicial" => "714" "paginaFinal" => "721" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/1545093" "web" => "Medline" ] ] ] ] ] ] ] ] 63 => array:3 [ "identificador" => "bib0320" "etiqueta" => "64." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Steroid-resistant asthma. Cellular mechanisms contributing to inadequate response to glucocorticoid therapy" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "E.R. Sher" 1 => "D.Y.M. Leung" 2 => "W. Surs" 3 => "J.C. Kam" 4 => "G. Zieg" 5 => "A.K. Kamada" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1172/JCI116963" "Revista" => array:6 [ "tituloSerie" => "J Clin Invest" "fecha" => "1994" "volumen" => "93" "paginaInicial" => "33" "paginaFinal" => "39" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8282803" "web" => "Medline" ] ] ] ] ] ] ] ] 64 => array:3 [ "identificador" => "bib0325" "etiqueta" => "65." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Combination of IL-2 and IL-4 reduces glucocorticoid-receptor binding affinity and T cell response to glucocorticoid" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "J.C. Kam" 1 => "S.J. Szefler" 2 => "W. Surs" 3 => "F.R. Sher" 4 => "D.Y.M. Leung" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "J Immunol" "fecha" => "1993" "volumen" => "151" "paginaInicial" => "3.460" "paginaFinal" => "3.466" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8258725" "web" => "Medline" ] ] ] ] ] ] ] ] 65 => array:3 [ "identificador" => "bib0330" "etiqueta" => "66." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Reduced glucocorticoid binding affinity in asthma is related to ongoing allergic inflammation" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "J.D. Spahn" 1 => "D.Y.M. Leung" 2 => "W. Surs" 3 => "R.J. Harbeck" 4 => "S. Nimmagadda" 5 => "S.J. Szefler" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1164/ajrccm.151.6.7767560" "Revista" => array:6 [ "tituloSerie" => "Am J Respir Crit Care Med" "fecha" => "1995" "volumen" => "151" "paginaInicial" => "1.709" "paginaFinal" => "1.714" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/7767560" "web" => "Medline" ] ] ] ] ] ] ] ] 66 => array:3 [ "identificador" => "bib0335" "etiqueta" => "67." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Circulating autoantibodies to recombinant lipocortin-1 in asthma" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "K.F. Chung" 1 => "M.R. Podgorski" 2 => "N.J. Goulding" 3 => "J.L. Godolphin" 4 => "P.R. Sharland" 5 => "B. O’Connor" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Respir Med" "fecha" => "1991" "volumen" => "85" "paginaInicial" => "121" "paginaFinal" => "124" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/1832234" "web" => "Medline" ] ] ] ] ] ] ] ] 67 => array:3 [ "identificador" => "bib0340" "etiqueta" => "68." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Differences in binding of glucocorticoid receptor to DNA in steroid-resistant asthma" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "I.M. Adcock" 1 => "S.J. Lane" 2 => "C.R. Brown" 3 => "M.J. Peters" 4 => "T.H. Lee" 5 => "P.J. Barnes" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "J Immunol" "fecha" => "1995" "volumen" => "154" "paginaInicial" => "3.500" "paginaFinal" => "3.505" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/7759895" "web" => "Medline" ] ] ] ] ] ] ] ] 68 => array:3 [ "identificador" => "bib0345" "etiqueta" => "69." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Abnormal glucocorticoid receptor-interaction in steroid-resistant asthma" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "I.M. Adcock" 1 => "S.J. Lane" 2 => "C.R. Brown" 3 => "T.H. Lee" 4 => "P.J. Barnes" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "J Exp Med" "fecha" => "1995" "volumen" => "182" "paginaInicial" => "1.951" "paginaFinal" => "1.958" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/7500055" "web" => "Medline" ] ] ] ] ] ] ] ] 69 => array:3 [ "identificador" => "bib0350" "etiqueta" => "70." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Cross-coupling of signal transduction pathways: zinc finger meets leucine zipper" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "R. Schüle" 1 => "R.M. Evans" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Trends Genet" "fecha" => "1991" "volumen" => "7" "paginaInicial" => "377" "paginaFinal" => "381" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/1668190" "web" => "Medline" ] ] ] ] ] ] ] ] 70 => array:3 [ "identificador" => "bib0355" "etiqueta" => "71." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "High concentrations of beta-adrenergic agonists inhibit DNA binding of glucocorticoids in human lung in vitro" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "I.M. Adcock" 1 => "M.J. Peters" 2 => "C.R. Brown" 3 => "D.A. Stevens" 4 => "P.J. Barnes" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:4 [ "tituloSerie" => "Biochem Soc Trans" "fecha" => "1995" "volumen" => "23" "paginaInicial" => "217" ] ] ] ] ] ] 71 => array:3 [ "identificador" => "bib0360" "etiqueta" => "72." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "National Asthma Education Program. Expert Panel Report. Guidelines for the diagnosis and management of asthma" "autores" => array:1 [ 0 => array:2 [ "colaboracion" => "National Heart. Lung Blood Institute" "etal" => false ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "J Allergy Clin Immunol" "fecha" => "1991" "volumen" => "83" "paginaInicial" => "425" "paginaFinal" => "534" ] ] ] ] ] ] 72 => array:3 [ "identificador" => "bib0365" "etiqueta" => "73." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Asthma\" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "R.A. Goldstein" 1 => "W.E. Paul" 2 => "D.D. Metcalfe" 3 => "W.W. Busse" 4 => "E.R. Reece" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Ann Intern Med" "fecha" => "1994" "volumen" => "121" "paginaInicial" => "698" "paginaFinal" => "708" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/7944080" "web" => "Medline" ] ] ] ] ] ] ] ] 73 => array:3 [ "identificador" => "bib0370" "etiqueta" => "74." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:1 [ "titulo" => "Drugs used in the treatment of asthma" ] ] "host" => array:1 [ 0 => array:1 [ "LibroEditado" => array:4 [ "titulo" => "Goodman & Gilman's the pharmacological basis of therapeutics." "paginaInicial" => "659" "paginaFinal" => "682" "serieFecha" => "1996" ] ] ] ] ] ] 74 => array:3 [ "identificador" => "bib0375" "etiqueta" => "75." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:1 [ "autores" => array:1 [ 0 => array:2 [ "colaboracion" => "International Rhinitis Management Group" "etal" => false ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:8 [ "titulo" => "International Consensus Report on the diagnosis and management of rhinitis" "tituloSerie" => "Allergy" "fecha" => "1994" "volumen" => "49" "numero" => "Supl 19" "paginaInicial" => "5" "paginaFinal" => "34" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10707472" "web" => "Medline" ] ] ] ] ] ] ] ] 75 => array:3 [ "identificador" => "bib0380" "etiqueta" => "76." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Practical application of the international consensus on the management of rhinitis" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "V.J. Lund" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Clin Immunother" "fecha" => "1995" "volumen" => "4" "paginaInicial" => "270" "paginaFinal" => "278" ] ] ] ] ] ] 76 => array:3 [ "identificador" => "bib0385" "etiqueta" => "77." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:1 [ "titulo" => "Position statement on nasal polyposis" ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Rhinology" "fecha" => "1994" "volumen" => "32" "paginaInicial" => "1.256" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/7701224" "web" => "Medline" ] ] ] ] ] ] ] ] 77 => array:3 [ "identificador" => "bib0390" "etiqueta" => "78." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Clinical pharmacology of corticosteroids in bronchial asthma" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "B.J. Lipworth" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Pharmacol Ther" "fecha" => "1993" "volumen" => "58" "paginaInicial" => "173" "paginaFinal" => "209" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8415878" "web" => "Medline" ] ] ] ] ] ] ] ] 78 => array:3 [ "identificador" => "bib0395" "etiqueta" => "79." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Pharmacokinetic optimisation of asthma treatment" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "A.M. Taburet" 1 => "B. Schmit" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.2165/00003088-199426050-00006" "Revista" => array:6 [ "tituloSerie" => "Clin Pharmacokinet" "fecha" => "1994" "volumen" => "26" "paginaInicial" => "396" "paginaFinal" => "418" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/7914480" "web" => "Medline" ] ] ] ] ] ] ] ] 79 => array:3 [ "identificador" => "bib0400" "etiqueta" => "80." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Inhaled glucocorticoids for asthma" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "P.J. Barnes" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1056/NEJM199503303321307" "Revista" => array:6 [ "tituloSerie" => "N Engl J Med" "fecha" => "1995" "volumen" => "332" "paginaInicial" => "868" "paginaFinal" => "875" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/7870143" "web" => "Medline" ] ] ] ] ] ] ] ] 80 => array:3 [ "identificador" => "bib0405" "etiqueta" => "81." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Regular inhaled beta-agonist treatment in hronchial asthma" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "M.R. Sears" 1 => "D.R. Taylor" 2 => "C.G. Print" 3 => "D.G. Lake" 4 => "Q. Li" 5 => "E.M. Flannery" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Lancet" "fecha" => "1990" "volumen" => "336" "paginaInicial" => "1.391" "paginaFinal" => "1.396" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/1979414" "web" => "Medline" ] ] ] ] ] ] ] ] 81 => array:3 [ "identificador" => "bib0410" "etiqueta" => "82." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "β2-agonists and corticosteroids: new developments and controversies" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "A.E. Tattersfield" 1 => "P.J. Barnes" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1164/ajrccm/146.6.1582" "Revista" => array:6 [ "tituloSerie" => "Am Rev Respir Dis" "fecha" => "1992" "volumen" => "146" "paginaInicial" => "1.637" "paginaFinal" => "1.641" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/1456579" "web" => "Medline" ] ] ] ] ] ] ] ] 82 => array:3 [ "identificador" => "bib0415" "etiqueta" => "83." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Regulation of β-adrenergic receptors by steroid hormones" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "A.O. Davies" 1 => "R.J. Lefkowitz" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1146/annurev.ph.46.030184.001003" "Revista" => array:6 [ "tituloSerie" => "Annu Rev Physiol" "fecha" => "1984" "volumen" => "46" "paginaInicial" => "119" "paginaFinal" => "130" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/6324653" "web" => "Medline" ] ] ] ] ] ] ] ] ] ] ] ] ] "idiomaDefecto" => "es" "url" => "/03002896/0000003200000010/v1_201506230103/S030028961530689X/v1_201506230103/es/main.assets" "Apartado" => array:4 [ "identificador" => "9299" "tipo" => "SECCION" "es" => array:2 [ "titulo" => "Revisiones" "idiomaDefecto" => true ] "idiomaDefecto" => "es" ] "PDF" => "https://static.elsevier.es/multimedia/03002896/0000003200000010/v1_201506230103/S030028961530689X/v1_201506230103/es/main.pdf?idApp=UINPBA00003Z&text.app=https://archbronconeumol.org/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S030028961530689X?idApp=UINPBA00003Z" ]
| Year/Month | Html | Total | |
|---|---|---|---|
| 2024 November | 4 | 72 | 76 |
| 2024 October | 52 | 545 | 597 |
| 2024 September | 48 | 350 | 398 |
| 2024 August | 46 | 257 | 303 |
| 2024 July | 46 | 265 | 311 |
| 2024 June | 62 | 247 | 309 |
| 2024 May | 67 | 1762 | 1829 |
| 2024 April | 55 | 4160 | 4215 |
| 2024 March | 48 | 2947 | 2995 |
| 2024 February | 35 | 2416 | 2451 |
| 2024 January | 0 | 1596 | 1596 |
| 2023 December | 0 | 1043 | 1043 |
| 2023 November | 0 | 3110 | 3110 |
| 2023 October | 0 | 2935 | 2935 |
| 2023 September | 0 | 2056 | 2056 |
| 2023 August | 0 | 1031 | 1031 |
| 2023 July | 0 | 312 | 312 |
| 2023 June | 0 | 52 | 52 |
| 2023 May | 0 | 15 | 15 |
| 2023 April | 0 | 12 | 12 |
| 2023 March | 5 | 245 | 250 |
| 2023 February | 45 | 1097 | 1142 |
| 2023 January | 45 | 846 | 891 |
| 2022 December | 44 | 976 | 1020 |
| 2022 November | 56 | 2337 | 2393 |
| 2022 October | 42 | 2217 | 2259 |
| 2022 September | 40 | 1937 | 1977 |
| 2022 August | 64 | 1487 | 1551 |
| 2022 July | 60 | 1365 | 1425 |
| 2022 June | 84 | 1617 | 1701 |
| 2022 May | 62 | 2188 | 2250 |
| 2022 April | 72 | 1624 | 1696 |
| 2022 March | 51 | 1836 | 1887 |
| 2022 February | 79 | 1303 | 1382 |
| 2022 January | 65 | 1076 | 1141 |
| 2021 December | 58 | 1416 | 1474 |
| 2021 November | 41 | 2012 | 2053 |
| 2021 October | 50 | 2178 | 2228 |
| 2021 September | 19 | 1588 | 1607 |
| 2021 August | 14 | 1376 | 1390 |
| 2021 July | 20 | 1611 | 1631 |
| 2021 June | 35 | 1503 | 1538 |
| 2021 May | 23 | 1511 | 1534 |
| 2021 April | 34 | 3140 | 3174 |
| 2021 March | 26 | 2118 | 2144 |
| 2021 February | 9 | 1429 | 1438 |
| 2021 January | 25 | 2192 | 2217 |
| 2020 December | 17 | 2910 | 2927 |
| 2020 November | 20 | 4355 | 4375 |
| 2020 October | 23 | 2563 | 2586 |
| 2020 September | 30 | 4634 | 4664 |
| 2020 August | 23 | 3145 | 3168 |
| 2020 July | 24 | 3509 | 3533 |
| 2020 June | 17 | 4061 | 4078 |
| 2020 May | 29 | 5177 | 5206 |
| 2020 April | 40 | 5865 | 5905 |
| 2020 March | 29 | 4812 | 4841 |
| 2020 February | 29 | 3594 | 3623 |
| 2020 January | 58 | 2450 | 2508 |
| 2019 December | 46 | 2662 | 2708 |
| 2019 November | 57 | 4754 | 4811 |
| 2019 October | 34 | 4747 | 4781 |
| 2019 September | 36 | 4216 | 4252 |
| 2019 August | 28 | 1980 | 2008 |
| 2019 July | 20 | 1988 | 2008 |
| 2019 June | 27 | 2809 | 2836 |
| 2019 May | 44 | 4196 | 4240 |
| 2019 April | 32 | 2753 | 2785 |
| 2019 March | 14 | 1530 | 1544 |
| 2019 February | 12 | 923 | 935 |
| 2019 January | 8 | 617 | 625 |
| 2018 December | 8 | 649 | 657 |
| 2018 November | 16 | 1502 | 1518 |
| 2018 October | 27 | 806 | 833 |
| 2018 September | 16 | 574 | 590 |
| 2018 May | 7 | 3 | 10 |
| 2018 April | 10 | 7 | 17 |
| 2018 March | 7 | 12 | 19 |
| 2018 February | 10 | 16 | 26 |
| 2018 January | 12 | 15 | 27 |
| 2017 December | 8 | 13 | 21 |
| 2017 November | 7 | 9 | 16 |
| 2017 October | 13 | 137 | 150 |
| 2017 September | 25 | 357 | 382 |
| 2017 August | 21 | 216 | 237 |
| 2017 July | 10 | 141 | 151 |
| 2017 June | 13 | 253 | 266 |
| 2017 May | 16 | 282 | 298 |
| 2017 April | 8 | 133 | 141 |
| 2017 March | 13 | 126 | 139 |
| 2017 February | 4 | 72 | 76 |
| 2017 January | 5 | 24 | 29 |
| 2016 December | 6 | 25 | 31 |
| 2016 November | 15 | 45 | 60 |
| 2016 October | 13 | 47 | 60 |
| 2016 September | 21 | 34 | 55 |
| 2016 August | 24 | 14 | 38 |
| 2016 July | 30 | 11 | 41 |
| 2016 June | 27 | 8 | 35 |
| 2016 May | 15 | 1 | 16 |
| 2016 April | 6 | 0 | 6 |
| 2016 March | 8 | 0 | 8 |
| 2016 February | 9 | 2 | 11 |
| 2016 January | 21 | 11 | 32 |
| 2015 December | 37 | 15 | 52 |
| 2015 November | 30 | 8 | 38 |
| 2015 October | 9 | 3 | 12 |
| 2015 September | 1 | 0 | 1 |
| 2015 June | 1 | 0 | 1 |
Show all
