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Sistemas de valoración clínica en el diagnóstico del tromboembolismo pulmonar (TEP)
Clinical evaluation systems for diagnosing pulmonary thromboembolism
R. Otero-Candelera*,1, A. Cayuela Domínguez**, M. Arenas*, A. Segado Soriano*, E. Barrot Cortés*, A. Verano Rodríguez*
* Servicios de Neumología, Hospital Universitario Virgen del Rocío. Sevilla
** Servicios de Epidemiología Clínica. Hospital Universitario Virgen del Rocío. Sevilla
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        "resumen" => "<span id="abst0005" class="elsevierStyleSection elsevierViewall"><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Nos propusimos desarrollar en nuestro medio los dos sistemas de valoraci&#243;n de la presencia de TEP a partir de la evaluaci&#243;n cl&#237;nica del paciente &#40;cuestionario estandarizado y modelos multivariantes&#41;&#46;</p><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Desde septiembre de 1993 hasta noviembre de 1994 se recogieron los datos &#40;historia cl&#237;nica&#44; exploraci&#243;n&#44; pruebas complementarias&#41; de los pacientes ingresados en nuestra planta de hospitalizaci&#243;n por sospecha de TEP&#46; Las <span class="elsevierStyleItalic">odds ratio</span> calculadas de cada una de las variables recogidas se utilizaron como pesos para determinar la pertenencia o no al grupo de riesgo de TEP&#46; Adem&#225;s&#44; se realiz&#243; un an&#225;lisis de regresi&#243;n log&#237;stica m&#250;ltiple&#46; El rendimiento de los dos sistemas de valoraci&#243;n creados &#40;sistemas de pesos y modelo log&#237;stico&#41; se estudi&#243; mediante la construcci&#243;n de las curvas ROC&#46; Fueron ingresados 82 pacientes&#58; 40 mujeres y 42 varones con una edad media de 60&#44;94<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>14&#44;39 a&#241;os&#46; Mediante el cuestionario se lleg&#243; a obtener una sensibilidad del 88&#37;&#44; una especificidad del 75&#37;&#44; un valor predictivo positivo del 94&#37; y un valor predictivo negativo del 60&#37;&#46; Con la aplicaci&#243;n de un modelo de regresi&#243;n log&#237;stica&#44; se obtuvo una sensibilidad del 96&#44;3&#37; para el diagn&#243;stico de TEP&#44; incluyendo las siguientes variables&#58; sexo femenino&#44; inmovilizaci&#243;n por causa m&#233;dica&#44; presencia cl&#237;nica de trombosis venosa profunda &#40;TVP&#41; en miembros inferiores y aparici&#243;n de disnea injustificada&#46; Comparando ambos m&#233;todos ninguno de ambos sistemas apareci&#243; claramente superior al otro en la valoraci&#243;n cl&#237;nica para el diagn&#243;stico de TEP&#46;</p></span>"
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        "resumen" => "<span id="abst0010" class="elsevierStyleSection elsevierViewall"><p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">We proposed developing two symptom-based systems for assessing the presence of pulmonary thromboembolism &#40;TEP&#41; in our practice&#44; using a standardized questionnaire and multivariate models&#46;</p><p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">Data were collected from September 1993 through November 1994 &#40;case reports&#44; physical examination findings and complementary test results&#41; of patients admitted to our ward with a suspicion of TEP&#46; The calculated odds ratio for each of the variables recorded were used as weights to determine their relevance or not for the group at risk for TEP&#46; The yield of the two systems developed &#40;a weights system and a logistical model&#41; were studied by plotting ROC curves&#46; Eighty-two patients &#40;40 women and 42 men&#44; mean age 60&#46;94<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>14&#46;39 years&#41; were admitted&#46; The questionnaire had a sensitivity of 88&#37; and a specificity of 75&#37;&#44; a positive predictive value of 94&#37; and a negative predictive value of 60&#37;&#46; The logistical regression model had a sensitivity of 96&#46;3&#37; for a diagnosis of TEP with inclusion of the following variables&#58; female sex&#44; disease-related immobility&#44; presence of deep venous thrombosis &#40;DVT&#41; in the lower extremities and the appearance of unexplained dyspnea&#46; Neither system was clearly superior to the other for arriving at a clinical diagnosis of TEP&#46;</p></span>"
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ISSN: 03002896
Original language: Spanish
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