Manejo de la patología pleural
Management of pleural disease
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array:22 [ "pii" => "S0300289609728546" "issn" => "03002896" "doi" => "10.1016/S0300-2896(09)72854-6" "estado" => "S300" "fechaPublicacion" => "2009-03-01" "aid" => "72854" "copyright" => "Sociedad Española de Neumología y Cirugía Torácica" "copyrightAnyo" => "2009" "documento" => "article" "crossmark" => 0 "subdocumento" => "fla" "cita" => "Arch Bronconeumol. 2009;45 Supl 3:22-7" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 11702 "formatos" => array:3 [ "EPUB" => 91 "HTML" => 8867 "PDF" => 2744 ] ] "itemAnterior" => array:18 [ "pii" => "S0300289609728534" "issn" => "03002896" "doi" => "10.1016/S0300-2896(09)72853-4" "estado" => "S300" "fechaPublicacion" => "2009-03-01" "aid" => "72853" "copyright" => "Sociedad Española de Neumología y Cirugía Torácica" "documento" => "article" "crossmark" => 0 "subdocumento" => "fla" "cita" => "Arch Bronconeumol. 2009;45 Supl 3:14-21" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 4546 "formatos" => array:3 [ "EPUB" => 103 "HTML" => 3344 "PDF" => 1099 ] ] "es" => array:10 [ "idiomaDefecto" => true "titulo" => "El síndrome de apnea-hipopnea del sueño en 2009" "tienePdf" => "es" "tieneTextoCompleto" => 0 "tieneResumen" => array:2 [ 0 => "es" 1 => "en" ] "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "14" "paginaFinal" => "21" ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Sleep apnea-hypopnea syndrome 2009" ] ] "contieneResumen" => array:2 [ "es" => true "en" => true ] "contienePdf" => array:1 [ "es" => true ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "Ana Camarasa Escrig, Demetrio González Vergara, José Carlos Serrano Rebollo, Ferran Barbé" "autores" => array:4 [ 0 => array:2 [ "nombre" => "Ana Camarasa" "apellidos" => "Escrig" ] 1 => array:2 [ "nombre" => "Demetrio González" "apellidos" => "Vergara" ] 2 => array:2 [ "nombre" => "José Carlos Serrano" "apellidos" => "Rebollo" ] 3 => array:2 [ "nombre" => "Ferran" "apellidos" => "Barbé" ] ] ] ] ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0300289609728534?idApp=UINPBA00003Z" "url" => "/03002896/00000045000000S3/v1_201305150247/S0300289609728534/v1_201305150247/es/main.assets" ] "es" => array:12 [ "idiomaDefecto" => true "titulo" => "Manejo de la patología pleural" "tieneTextoCompleto" => 0 "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "22" "paginaFinal" => "27" ] ] "autores" => array:1 [ 0 => array:4 [ "autoresLista" => "Francisco Rodríguez-Panadero, Myriam Aguilar Pérez, Manuel Alejandro Muñoz Moya, María Isabel Asensio Cruz" "autores" => array:4 [ 0 => array:4 [ "nombre" => "Francisco" "apellidos" => "Rodríguez-Panadero" "email" => array:1 [ 0 => "frpanad@ono.com" ] "referencia" => array:2 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff1" ] 1 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">¿</span>" "identificador" => "cor1" ] ] ] 1 => array:3 [ "nombre" => "Myriam Aguilar" "apellidos" => "Pérez" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff2" ] ] ] 2 => array:3 [ "nombre" => "Manuel Alejandro Muñoz" "apellidos" => "Moya" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">c</span>" "identificador" => "aff3" ] ] ] 3 => array:3 [ "nombre" => "María Isabel Asensio" "apellidos" => "Cruz" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff1" ] ] ] ] "afiliaciones" => array:3 [ 0 => array:3 [ "entidad" => "Unidad Médico-Quirúrgica de Enfermedades Respiratorias, Hospital Universitario Virgen del Rocío, Sevilla, España" "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff1" ] 1 => array:3 [ "entidad" => "Servicio de Neumología, Hospital Universitario 12 de Octubre, Madrid, España" "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff2" ] 2 => array:3 [ "entidad" => "Unidad de Neumología, Consorcio hospitalario provincial de Castellón, Castellón, España" "etiqueta" => "<span class="elsevierStyleSup">c</span>" "identificador" => "aff3" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor1" "etiqueta" => "⁎" "correspondencia" => "Autor para correspondencia." ] ] ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Management of pleural disease" ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "PalabrasClave" => array:2 [ "es" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palabras clave" "identificador" => "xpalclavsec154420" "palabras" => array:8 [ 0 => "Adenosindesaminasa" 1 => "Derrame paraneumónico" 2 => "Derrame pleural" 3 => "Empiema" 4 => "Interferón gamma" 5 => "Mesotelina" 6 => "Mesotelioma" 7 => "Tuberculosis pleural" ] ] ] "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Keywords" "identificador" => "xpalclavsec154419" "palabras" => array:8 [ 0 => "Adenosine deaminase" 1 => "Parapneumonic effusion" 2 => "Pleural effusion" 3 => "Empyema" 4 => "Interferon gamma" 5 => "Mesothelin" 6 => "Mesothelioma" 7 => "Pleural tuberculosis" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "es" => array:2 [ "titulo" => "Resumen" "resumen" => "<p class="elsevierStyleSimplePara elsevierViewall">Teniendo en cuenta las ponencias presentadas en el I Foro Nacional de Neumólogos en Formación, nos centramos aquí en los derrames pleurales de origen infeccioso y sobre el estudio de posibles marcadores de malignización en sujetos con historia de exposición a asbesto. Se analiza el rendimiento de las distintas técnicas para el diagnóstico del derrame tuberculoso, haciendo hincapié en el estudio del esputo y de las muestras pleurales (líquido y tejido) para <span class="elsevierStyleItalic">Mycobacterium</span><span class="elsevierStyleItalic">tuberculosis,</span> y en el rendimiento de la adenosindesaminasa (ADA) (en ausencia de empiema, ADA > 70 U/l es diagnóstico de pleuritis tuberculosa, y niveles inferiores a 40 U/l la excluyen prácticamente) e interferón gamma en el líquido pleural (punto de corte: 3,7 UI/ml). El manejo de los derrames pleurales paraneumónicos se estratifica en cuatro categorías, atendiendo a las características anatomo-morfológicas (tamaño y eventual presencia de loculación), bacteriológicas (positividad o no del cultivo del líquido pleural) y bioquímicas (pH/glucosa) del derrame. Finalmente, se describen algunos marcadores desarrollados recientemente para el estudio y seguimiento de personas expuestas a asbesto, con especial hincapié en la determinación de niveles de mesotelina en suero, que parece muy prometedora como marcador del desarrollo de mesotelioma en estos casos. Niveles de SMRP (proteínas solubles relacionadas con la mesotelina) superiores a 0,55 nmol/l mostraron un 72% de sensibilidad y especificidad para el diagnóstico de mesotelioma maligno de estirpe epitelial en un estudio multicéntrico que actualmente se está llevando a cabo en nuestro país.</p>" ] "en" => array:2 [ "titulo" => "Abstract" "resumen" => "<p class="elsevierStyleSimplePara elsevierViewall">In view of the presentations in the First National Forum of Trainee Pneumologists, the present article focusses on infectious pleural effusions and on the study of possible markers of malignant disease in asbestos-exposed individuals. The yield of the distinct techniques for the diagnosis of tuberculous pleural effusion is assessed, with emphasis on analysis of sputum and pleural samples (fluid and tissue) for <span class="elsevierStyleItalic">Mycobacterium</span><span class="elsevierStyleItalic">tuberculosis</span>. The utility of adenosine deaminase (ADA) (in the absence of empyema, ADA > 70 U/l is diagnostic of tuberculous pleurisy, while values of less than 40 U/l exclude this diagnosis) and interferon gamma in pleural fluid (cut off: 3.7 Ul/ml) is also discussed. The management of complicated parapneumonic pleural effusions is stratified in four categories, depending on the anatomical and morphological (size and eventual presence of loculations), bacteriological (positivity or negativity of pleural fluid culture) and biochemical (pH/glucose) characteristics of the effusion. Finally, recently developed markers for the evaluation and follow-up of asbestos-exposed individuals are described, with special emphasis on serum determination of mesothelin levels, which seem highly promising as a marker of the development of mesothelioma in these cases. A multicenter study currently being performed in Spain found that soluble mesothelin-related protein (SMRP) levels higher than 0.55 nmol/L showed a sensitivity and specificity of 72% for the diagnosis of epithelial malignant mesothelioma.</p>" ] ] "bibliografia" => array:2 [ "titulo" => "Bibliografía" "seccion" => array:1 [ 0 => array:1 [ "bibliografiaReferencia" => array:42 [ 0 => array:3 [ "identificador" => "bib1" "etiqueta" => "1." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Diagnóstico y tratamiento del derrame pleural" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "V. Villena Garrido" 1 => "J. Ferrer Sancho" 2 => "L. 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Copin" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/j.clinbiochem.2009.03.007" "Revista" => array:6 [ "tituloSerie" => "Clin Biochem" "fecha" => "2009" "volumen" => "42" "paginaInicial" => "1046" "paginaFinal" => "1050" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/19302997" "web" => "Medline" ] ] ] ] ] ] ] ] ] ] ] ] ] "idiomaDefecto" => "es" "url" => "/03002896/00000045000000S3/v1_201305150247/S0300289609728546/v1_201305150247/es/main.assets" "Apartado" => null "PDF" => "https://static.elsevier.es/multimedia/03002896/00000045000000S3/v1_201305150247/S0300289609728546/v1_201305150247/es/main.pdf?idApp=UINPBA00003Z&text.app=https://archbronconeumol.org/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0300289609728546?idApp=UINPBA00003Z" ]
| Year/Month | Html | Total | |
|---|---|---|---|
| 2024 November | 8 | 5 | 13 |
| 2024 October | 51 | 29 | 80 |
| 2024 September | 60 | 31 | 91 |
| 2024 August | 74 | 48 | 122 |
| 2024 July | 37 | 25 | 62 |
| 2024 June | 48 | 37 | 85 |
| 2024 May | 72 | 28 | 100 |
| 2024 April | 52 | 31 | 83 |
| 2024 March | 52 | 35 | 87 |
| 2024 February | 42 | 30 | 72 |
| 2023 May | 0 | 2 | 2 |
| 2023 March | 6 | 3 | 9 |
| 2023 February | 34 | 26 | 60 |
| 2023 January | 27 | 25 | 52 |
| 2022 December | 32 | 30 | 62 |
| 2022 November | 46 | 23 | 69 |
| 2022 October | 41 | 27 | 68 |
| 2022 September | 39 | 23 | 62 |
| 2022 August | 63 | 50 | 113 |
| 2022 July | 40 | 44 | 84 |
| 2022 June | 43 | 32 | 75 |
| 2022 May | 43 | 47 | 90 |
| 2022 April | 47 | 26 | 73 |
| 2022 March | 67 | 39 | 106 |
| 2022 February | 45 | 34 | 79 |
| 2022 January | 56 | 40 | 96 |
| 2021 December | 44 | 49 | 93 |
| 2021 November | 44 | 52 | 96 |
| 2021 October | 61 | 49 | 110 |
| 2021 September | 61 | 66 | 127 |
| 2021 August | 20 | 43 | 63 |
| 2021 July | 41 | 47 | 88 |
| 2021 June | 47 | 46 | 93 |
| 2021 May | 42 | 51 | 93 |
| 2021 April | 126 | 98 | 224 |
| 2021 March | 100 | 46 | 146 |
| 2021 February | 75 | 33 | 108 |
| 2021 January | 55 | 53 | 108 |
| 2020 December | 31 | 33 | 64 |
| 2020 November | 38 | 23 | 61 |
| 2020 October | 41 | 14 | 55 |
| 2020 September | 42 | 24 | 66 |
| 2020 August | 39 | 30 | 69 |
| 2020 July | 54 | 27 | 81 |
| 2020 June | 35 | 19 | 54 |
| 2020 May | 47 | 29 | 76 |
| 2020 April | 32 | 12 | 44 |
| 2020 March | 47 | 30 | 77 |
| 2020 February | 37 | 25 | 62 |
| 2020 January | 56 | 28 | 84 |
| 2019 December | 50 | 27 | 77 |
| 2019 November | 41 | 24 | 65 |
| 2019 October | 40 | 33 | 73 |
| 2019 September | 67 | 44 | 111 |
| 2019 August | 44 | 31 | 75 |
| 2019 July | 63 | 36 | 99 |
| 2019 June | 59 | 49 | 108 |
| 2019 May | 72 | 44 | 116 |
| 2019 April | 107 | 102 | 209 |
| 2019 March | 83 | 49 | 132 |
| 2019 February | 49 | 34 | 83 |
| 2019 January | 55 | 21 | 76 |
| 2018 December | 54 | 42 | 96 |
| 2018 November | 84 | 31 | 115 |
| 2018 October | 96 | 30 | 126 |
| 2018 September | 97 | 25 | 122 |
| 2018 July | 1 | 0 | 1 |
| 2018 May | 34 | 1 | 35 |
| 2018 April | 64 | 10 | 74 |
| 2018 March | 23 | 5 | 28 |
| 2018 February | 16 | 16 | 32 |
| 2018 January | 16 | 11 | 27 |
| 2017 December | 36 | 22 | 58 |
| 2017 November | 106 | 40 | 146 |
| 2017 October | 67 | 18 | 85 |
| 2017 September | 71 | 41 | 112 |
| 2017 August | 55 | 41 | 96 |
| 2017 July | 52 | 43 | 95 |
| 2017 June | 55 | 57 | 112 |
| 2017 May | 19 | 42 | 61 |
| 2017 April | 29 | 51 | 80 |
| 2017 March | 30 | 80 | 110 |
| 2017 February | 41 | 97 | 138 |
| 2017 January | 17 | 47 | 64 |
| 2016 December | 40 | 82 | 122 |
| 2016 November | 68 | 160 | 228 |
| 2016 October | 60 | 195 | 255 |
| 2016 September | 84 | 213 | 297 |
| 2016 August | 169 | 146 | 315 |
| 2016 July | 132 | 81 | 213 |
| 2016 June | 107 | 71 | 178 |
| 2016 May | 120 | 65 | 185 |
| 2016 April | 34 | 0 | 34 |
| 2016 March | 39 | 2 | 41 |
| 2016 February | 72 | 11 | 83 |
| 2016 January | 131 | 107 | 238 |
| 2015 December | 153 | 130 | 283 |
| 2015 November | 242 | 180 | 422 |
| 2015 October | 227 | 9 | 236 |
| 2015 September | 170 | 0 | 170 |
| 2015 August | 168 | 0 | 168 |
| 2015 July | 164 | 0 | 164 |
| 2015 June | 154 | 0 | 154 |
| 2015 May | 252 | 0 | 252 |
| 2015 April | 181 | 0 | 181 |
| 2015 March | 183 | 0 | 183 |
| 2015 February | 125 | 0 | 125 |
| 2015 January | 129 | 0 | 129 |
| 2014 December | 106 | 0 | 106 |
| 2014 November | 171 | 0 | 171 |
| 2014 October | 210 | 0 | 210 |
| 2014 September | 203 | 0 | 203 |
| 2014 August | 188 | 0 | 188 |
| 2014 July | 175 | 0 | 175 |
| 2014 June | 192 | 0 | 192 |
| 2014 May | 205 | 0 | 205 |
| 2014 April | 132 | 0 | 132 |
| 2014 March | 123 | 0 | 123 |
| 2014 February | 103 | 0 | 103 |
| 2014 January | 80 | 0 | 80 |
| 2013 December | 87 | 0 | 87 |
| 2013 November | 133 | 0 | 133 |
| 2013 October | 134 | 0 | 134 |
| 2013 September | 138 | 0 | 138 |
| 2013 August | 156 | 0 | 156 |
| 2013 July | 138 | 0 | 138 |
| 2013 June | 92 | 0 | 92 |
| 2013 May | 120 | 0 | 120 |
| 2013 April | 115 | 0 | 115 |
| 2013 March | 82 | 0 | 82 |
| 2000 January | 704 | 0 | 704 |
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