Aspectos relevantes en el manejo de la enfermedad pulmonar intersticial difusa
Key features in the management of diffuse interstitial pulmonary disease
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[ 0 => array:4 [ "autoresLista" => "David Iturbe Fernández, Ricardo Peris Sánchez, Alicia Ferreira Moreno, Estrella Fernández Fabrellas" "autores" => array:4 [ 0 => array:3 [ "nombre" => "David Iturbe" "apellidos" => "Fernández" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff1" ] ] ] 1 => array:3 [ "nombre" => "Ricardo Peris" "apellidos" => "Sánchez" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff2" ] ] ] 2 => array:3 [ "nombre" => "Alicia Ferreira" "apellidos" => "Moreno" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">c</span>" "identificador" => "aff3" ] ] ] 3 => array:4 [ "nombre" => "Estrella Fernández" "apellidos" => "Fabrellas" "email" => array:1 [ 0 => "fernandez_est@gva.es" ] "referencia" => array:2 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff2" ] 1 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">¿</span>" "identificador" => "cor1" ] ] ] ] "afiliaciones" => array:3 [ 0 => array:3 [ "entidad" => "Hospital Universitario Marqués de Valdecilla, Santander, España" "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff1" ] 1 => array:3 [ "entidad" => "Hospital Universitario Dr. Peset, Valencia, España" "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff2" ] 2 => array:3 [ "entidad" => "Hospital General Universitario Gregorio Marañón, Madrid, España" "etiqueta" => "<span class="elsevierStyleSup">c</span>" "identificador" => "aff3" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor1" "etiqueta" => "⁎" "correspondencia" => "Autor para correspondencia." ] ] ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Key features in the management of diffuse interstitial pulmonary disease" ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "PalabrasClave" => array:2 [ "es" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palabras clave" "identificador" => "xpalclavsec154412" "palabras" => array:4 [ 0 => "Enfermedad pulmonar intersicial difusa" 1 => "Exacerbación" 2 => "Factores pronósticos" 3 => "Opciones terapéuticas" ] ] ] "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Keywords" "identificador" => "xpalclavsec154413" "palabras" => array:4 [ 0 => "Diffuse interstitial lung disease" 1 => "Exacerbation" 2 => "Prognostic factors" 3 => "Therapeutic options" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "es" => array:2 [ "titulo" => "Resumen" "resumen" => "<p class="elsevierStyleSimplePara elsevierViewall">Las enfermedades pulmonares intersticiales difusas (EPID) son un grupo heterogéneo de entidades en las que el denominador común es la afectación de la zona anatómica existente entre la membrana basal del epitelio alveolar y el endotelio capilar, conocido como espacio intersticial. El abordaje diagnóstico, las complicaciones que pueden aparecer en la historia natural de estas enfermedades y sus escasas alternativas terapéuticas hacen de ellas un auténtico reto para el clínico. En esta breve revisión se incidirá en los aspectos más relevantes del manejo de las EPID como son los factores pronósticos, las opciones terapéuticas, incluido el papel del trasplante pulmonar, y el diagnóstico y tratamiento de dos complicaciones de trascendental relevancia en su evolución, como son las exacerbaciones y la hipertensión pulmonar asociada.</p>" ] "en" => array:2 [ "titulo" => "Abstract" "resumen" => "<p class="elsevierStyleSimplePara elsevierViewall">Diffuse interstitial lung disease is a heterogeneous group of diseases in which the common denominator is involvement of the area between the basement membrane of the alveolar epithelium and the capillary endothelium, known as the interstitial space. Diffuse interstitial lung disease poses a tremendous challenge to the clinician due to the diagnostic approach, the complications that can appear in the natural history of these entities, and the scarcity of available therapeutic resources. This brief review discusses key features of the management of diffuse interstitial pulmonary disease, such as prognostic factors, the therapeutic options –including the role of lung transplantation– and the diagnosis and treatment of two complications with crucial impact on the clinical course of the disease: exacerbations and associated pulmonary hypertension.</p>" ] ] "bibliografia" => array:2 [ "titulo" => "Bibliografía" "seccion" => array:1 [ 0 => array:1 [ "bibliografiaReferencia" => array:39 [ 0 => array:3 [ "identificador" => "bib1" "etiqueta" => "1." 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| Year/Month | Html | Total | |
|---|---|---|---|
| 2024 November | 4 | 3 | 7 |
| 2024 October | 60 | 33 | 93 |
| 2024 September | 68 | 20 | 88 |
| 2024 August | 109 | 43 | 152 |
| 2024 July | 40 | 27 | 67 |
| 2024 June | 73 | 29 | 102 |
| 2024 May | 75 | 33 | 108 |
| 2024 April | 49 | 29 | 78 |
| 2024 March | 35 | 36 | 71 |
| 2024 February | 53 | 43 | 96 |
| 2023 June | 4 | 1 | 5 |
| 2023 March | 7 | 7 | 14 |
| 2023 February | 37 | 24 | 61 |
| 2023 January | 44 | 31 | 75 |
| 2022 December | 50 | 38 | 88 |
| 2022 November | 48 | 22 | 70 |
| 2022 October | 53 | 37 | 90 |
| 2022 September | 39 | 24 | 63 |
| 2022 August | 33 | 42 | 75 |
| 2022 July | 62 | 42 | 104 |
| 2022 June | 57 | 40 | 97 |
| 2022 May | 48 | 43 | 91 |
| 2022 April | 51 | 29 | 80 |
| 2022 March | 75 | 44 | 119 |
| 2022 February | 67 | 66 | 133 |
| 2022 January | 55 | 52 | 107 |
| 2021 December | 46 | 49 | 95 |
| 2021 November | 40 | 58 | 98 |
| 2021 October | 70 | 37 | 107 |
| 2021 September | 41 | 61 | 102 |
| 2021 August | 54 | 66 | 120 |
| 2021 July | 54 | 32 | 86 |
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| 2021 May | 42 | 36 | 78 |
| 2021 April | 98 | 81 | 179 |
| 2021 March | 59 | 27 | 86 |
| 2021 February | 34 | 30 | 64 |
| 2021 January | 23 | 20 | 43 |
| 2020 December | 32 | 22 | 54 |
| 2020 November | 28 | 18 | 46 |
| 2020 October | 24 | 18 | 42 |
| 2020 September | 15 | 15 | 30 |
| 2020 August | 42 | 25 | 67 |
| 2020 July | 43 | 35 | 78 |
| 2020 June | 29 | 13 | 42 |
| 2020 May | 41 | 27 | 68 |
| 2020 April | 64 | 16 | 80 |
| 2020 March | 34 | 30 | 64 |
| 2020 February | 53 | 27 | 80 |
| 2020 January | 46 | 40 | 86 |
| 2019 December | 26 | 24 | 50 |
| 2019 November | 24 | 15 | 39 |
| 2019 October | 29 | 27 | 56 |
| 2019 September | 38 | 40 | 78 |
| 2019 August | 47 | 20 | 67 |
| 2019 July | 26 | 30 | 56 |
| 2019 June | 42 | 18 | 60 |
| 2019 May | 49 | 54 | 103 |
| 2019 April | 53 | 38 | 91 |
| 2019 March | 68 | 45 | 113 |
| 2019 February | 52 | 113 | 165 |
| 2019 January | 36 | 25 | 61 |
| 2018 December | 41 | 27 | 68 |
| 2018 November | 60 | 43 | 103 |
| 2018 October | 84 | 39 | 123 |
| 2018 September | 53 | 35 | 88 |
| 2018 May | 18 | 2 | 20 |
| 2018 April | 54 | 10 | 64 |
| 2018 March | 33 | 11 | 44 |
| 2018 February | 16 | 19 | 35 |
| 2018 January | 13 | 10 | 23 |
| 2017 December | 27 | 24 | 51 |
| 2017 November | 58 | 25 | 83 |
| 2017 October | 63 | 20 | 83 |
| 2017 September | 55 | 37 | 92 |
| 2017 August | 67 | 50 | 117 |
| 2017 July | 54 | 46 | 100 |
| 2017 June | 57 | 63 | 120 |
| 2017 May | 65 | 60 | 125 |
| 2017 April | 51 | 44 | 95 |
| 2017 March | 74 | 81 | 155 |
| 2017 February | 24 | 50 | 74 |
| 2017 January | 11 | 102 | 113 |
| 2016 December | 27 | 91 | 118 |
| 2016 November | 32 | 143 | 175 |
| 2016 October | 30 | 144 | 174 |
| 2016 September | 86 | 229 | 315 |
| 2016 August | 200 | 212 | 412 |
| 2016 July | 166 | 215 | 381 |
| 2016 June | 161 | 183 | 344 |
| 2016 May | 117 | 107 | 224 |
| 2016 April | 40 | 3 | 43 |
| 2016 March | 32 | 3 | 35 |
| 2016 February | 56 | 17 | 73 |
| 2016 January | 139 | 139 | 278 |
| 2015 December | 150 | 147 | 297 |
| 2015 November | 269 | 237 | 506 |
| 2015 October | 187 | 18 | 205 |
| 2015 September | 198 | 0 | 198 |
| 2015 August | 142 | 0 | 142 |
| 2015 July | 139 | 0 | 139 |
| 2015 June | 116 | 0 | 116 |
| 2015 May | 197 | 0 | 197 |
| 2015 April | 133 | 0 | 133 |
| 2015 March | 124 | 0 | 124 |
| 2015 February | 71 | 0 | 71 |
| 2015 January | 135 | 0 | 135 |
| 2014 December | 96 | 0 | 96 |
| 2014 November | 122 | 0 | 122 |
| 2014 October | 185 | 0 | 185 |
| 2014 September | 134 | 0 | 134 |
| 2014 August | 144 | 0 | 144 |
| 2014 July | 122 | 0 | 122 |
| 2014 June | 125 | 0 | 125 |
| 2014 May | 154 | 0 | 154 |
| 2014 April | 115 | 0 | 115 |
| 2014 March | 112 | 0 | 112 |
| 2014 February | 103 | 0 | 103 |
| 2014 January | 86 | 0 | 86 |
| 2013 December | 78 | 0 | 78 |
| 2013 November | 89 | 0 | 89 |
| 2013 October | 95 | 0 | 95 |
| 2013 September | 82 | 0 | 82 |
| 2013 August | 100 | 0 | 100 |
| 2013 July | 111 | 0 | 111 |
| 2013 June | 73 | 0 | 73 |
| 2013 May | 106 | 0 | 106 |
| 2013 April | 68 | 0 | 68 |
| 2013 March | 56 | 0 | 56 |
| 2000 January | 690 | 0 | 690 |
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