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Vol. 21. Issue 6.
Pages 266-268 (November - December 1985)
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Vol. 21. Issue 6.
Pages 266-268 (November - December 1985)
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Eosinofilia asociada a carcinoma pulmonar. Estudio clinico de 6 casos
Eosinophylia in association with cancer of the lung
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H. Verea Hernando, M.T. Martin Egaña, J. Masa Jimenez, L. Dominguez Juncal, J. Fontan Bueso
Sección de Neumología. C.S. Juan Canalejo. La Coruña
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Presentamos seis pacientes diagnosticados de carcinoma pulmonar (cuatro epidermoides, un indiferenciado de células grandes y un oat-cell) que cursaban con eosinofilia periférica (EP) entre 1.440 y 15.964/μl). En tres casos no se detectaron datos bioquímicos ni gammagráficos que sugiriesen metástasis. Aunque en tres pacientes la EP remitió con el tratamiento, en uno no se elevó significativamente con la recurrencia del proceso. La evolución fue más tórpida en los que tenian EP más elevada. Aunque, en ocasiones, puede facilitar la aparición de tromboembolias, su interés es de limitado valor en el manejo de la enfermedad de base.

The authors report seven patients with pulmonar) cancer (4 epidermoid, 1 undifferentiated giant cell and 1 oat cell) who presented peripherical eosinophylia (PE) between 1.440-15.964/ml. In 3 cases no biochemical nor gammagraphic data suggesting metastasis were found. Although in 3 of the patients the PE remitted with treatment, in another one recurrence of the process did not result in any significant elevation. Patients with the highest EP showed the slowest course. Although on certain occasions, PE may favour thromboembolisms, its presence in the particular patients is of limited value only.

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Bibliografía
[1.]
P.F. Weller.
Eosinophilia.
J Allergy Clin Immunol, 73 (1984), pp. 1-10
[2.]
W.J. Williams, E. Bentler, A. Erslen, M.A. Lichtman.
Hematology.
5 ed, Mac Graw Hill, (1983),
[3.]
D. Lowe, J. Jorizzo, M.S.R. Hutt.
Tumour-associated eosinophilia: a review.
J Clin Pathol, 34 (1981), pp. 1343-1348
[4.]
N.H. Isaacson, P. Rapaport.
Eosinophilia in malignant tumors: its significance.
Ann Intern Med, 25 (1946), pp. 893-902
[5.]
F. Lahoz.
Eosinofilia pulmonar. Introducción y clasificación. XII Congreso de la Sociedad Española de Alergia e Inmunología Clínica.
En: Allergol Immunopathol (Madrid), 7 (1980), pp. 39-40
[6.]
P.B. Beeson.
Cancer and eosinophilia (Editorial).
N Engl J Med, 309 (1983), pp. 792-793
[7.]
C. Noirot, F. Leynadier, H. Luce, N. Abuaf, Bernard PhF, J. Dry.
Hyperosinophilie au cours des cancers et des cirrhoses: M. térêt du compte absolu des eosinophiles.
Sem Hosp Paris, 58 (1982), pp. 133-137
[8.]
T.M. Healy.
Eosinophilia in bronchogenic carcinoma (Letter).
N Engl J Med, 291 (1974), pp. 794
[9.]
A.L. Dellon, R.B. Hume, P.B. Chretien.
Eosinophilia in bronchogenic carcinoma (Letter).
N Engl J Med, 291 (1974), pp. 207-208
[10.]
N.A. Ghossein, J.L. Bosworth, P. Stacey, F.M. Muggia, V. Krishnaswamy.
Radiation-related eosinophilia.
Radiology, 117 (1975), pp. 413-417
[11.]
S.I. Wasserman, E.J. Goetzl, L. Ellman, K.F. Ansten.
Tumor associated eosinophilotactic factor.
N Engl J Med, 290 (1974), pp. 420-424
[12.]
E.J. Goetzl, A.H. Tashjian, R.H. Rubin, F. Ansten.
Production of a low molecular weight eosinophil polimorphonuclear leukocyte chemotactic factor by anaplastic squamous cellcarcinomas of human lung.
J Clin Invest, 61 (1978), pp. 770-780
[13.]
A. Slungaard, J. Ascensao, E. Zangani, H. Jacols.
Pulmonary carcinoma with eosinophilia.
N Engl J Med, 309 (1983), pp. 778-781
[14.]
R.S. Ramaiah, R.W. Biagi.
Eosinophilia: an unusual presentaron of carcinoma of the lung.
Practicioner, 226 (1982), pp. 1805-1806
[15.]
A.J. Barrett, A. Barret.
Bronchial carcinoma with eosinophilia and cardiomegaly.
Brit J Dis Chest, 69 (1975), pp. 287-292
[16.]
R.J. Fahey.
Unusual leukocyte responses in primary carcinoma of the lung.
Cancer, 4 (1951), pp. 930-935
[17.]
A. Churg.
The fine structure of large cell indifferentiated carcinoma of the lung: evidence for its relation to squamous cell carcinomas and adenocarcinomas.
Human Pathol, 9 (1978), pp. 143-156
[18.]
T. Tada.
Regulation of reaginic antibody formation in animals.
Prog Allergy, 19 (1975), pp. 122-127
[19.]
A. Basten, P. Beeson.
Mechanism of eosinophilia II. Role of the lymphocite.
J Exp Med, (1970), pp. 1288-1305
[20.]
T. Takenaka, M. Okuda, K. Kubo, H. Uda.
Studies on interrelations between eosinophilia, serum IgE and tissue mast cells.
Clin Allergy, 5 (1975), pp. 175-180
[21.]
B. Hallgren, H. Arrendal, K. Hiesche, G. Lundquist, E. Nöu, O. Zetterström.
Elevated serum immunoglobulin E in bronchial carcinoma: its relation to the histology and prognosis of the cancer.
J Allergy Clin Immunol, 67 (1981), pp. 398-406
[22.]
E.G.J. Olsen, C.J.F. Spry.
The pathogenesis of Loeffler's endomyocardial disease and its relationship to endomyocardio Fibrosis.
Progres Cardiol, 8 (1979), pp. 281-303
[23.]
A.S. Fauci, (Moderador).
The idopathic hipereosinophilia syndrome. Clinical pathophysiologic and therapeutic considerations.
Ann Intern Med, 97 (1982), pp. 78-92
[24.]
E. Frigas, D.A. Loegerin, G.G. Gleich.
Cytotoxic effects of the guinea pig eosinophil major basic protein on tracheal epithelium.
Lab Invest, 42 (1980), pp. 35-43
Copyright © 1985. Sociedad Española de Neumología y Cirugía Torácica
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